Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in PTCT held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | BlackRock, Inc. | 12.9M | $882.2M | +1.3% | 15.610% | 0.02% |
| 2 | RTW INVESTMENTS, LP | 7.7M | $527.8M | 0.0% | 9.339% | 5.25% |
| 3 | JANUS HENDERSON GROUP PLC | 7.2M | $490.0M | +48.3% | 8.672% | 0.24% |
| 4 | VANGUARD PORTFOLIO MANAGEMENT LLC | 4.8M | $327.3M | β | 5.792% | 0.02% |
| 5 | STATE STREET CORP | 4.3M | $296.1M | +3.3% | 5.240% | 0.01% |
| 6 | WELLINGTON MANAGEMENT GROUP LLP | 3.9M | $268.6M | +1.9% | 4.753% | 0.05% |
| 7 | VANGUARD CAPITAL MANAGEMENT LLC | 3.7M | $250.5M | β | 4.432% | 0.01% |
| 8 | TORONTO DOMINION BANK | 3.0M | $206.2M | -26.9% | 3.648% | 0.30% |
| 9 | ARMISTICE CAPITAL, LLC | 2.5M | $167.9M | -12.0% | 2.971% | 4.95% |
| 10 | GEODE CAPITAL MANAGEMENT, LLC | 2.2M | $150.6M | +9.6% | 2.664% | 0.01% |
| 11 | BANK OF AMERICA CORP /DE/ | 1.9M | $128.6M | +31.8% | 2.275% | 0.01% |
| 12 | Hood River Capital Management LLC | 1.7M | $113.4M | +66.0% | 2.007% | 1.14% |
| 13 | D. E. Shaw & Co., Inc. | 1.6M | $111.8M | -6.0% | 1.978% | 0.11% |
| 14 | FMR LLC | 1.5M | $104.1M | -9.1% | 1.843% | 0.01% |
| 15 | TANG CAPITAL MANAGEMENT LLC | 1.5M | $102.2M | 0.0% | 1.808% | 5.19% |
| 16 | UBS Group AG | 1.4M | $93.0M | +41.5% | 1.645% | 0.01% |
| 17 | Jefferies Financial Group Inc. | 1.4M | $92.3M | -18.3% | 1.633% | 0.64% |
| 18 | Pictet Asset Management Holding SA | 1.2M | $80.1M | +20.9% | 1.427% | 0.09% |
| 19 | FRANKLIN RESOURCES INC | 1.1M | $76.4M | -12.8% | 1.352% | 0.02% |
| 20 | DRIEHAUS CAPITAL MANAGEMENT LLC | 1.0M | $69.2M | -10.6% | 1.225% | 0.51% |
| 21 | Palo Alto Investors LP | 922K | $62.8M | +2.0% | 1.111% | 9.60% |
| 22 | BNP PARIBAS ARBITRAGE, SA | 920K | $62.7M | +11.1% | 1.110% | 0.03% |
| 23 | DIMENSIONAL FUND ADVISORS LP | 891K | $60.7M | +42.0% | 1.074% | 0.01% |
| 24 | Invesco Ltd. | 865K | $59.0M | +99.3% | 1.043% | 0.01% |
| 25 | GOLDMAN SACHS GROUP INC | 828K | $56.4M | -19.1% | 0.998% | 0.01% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in PTCT β a direct measure of their conviction.
Filings activity in PTCT during Q1 2026, grouped by how each filer changed its position.
Institutions that opened a new PTCT position in Q1 2026
Institutions that fully closed their PTCT position in Q1 2026
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 345 | +0.9% | 102.12% | 5.96 pp | $6.36B | 5.5% |
| Q4 2025 | 342 | +18% | 108.08% | +27.93 pp | $6.74B | +35% |
| Q3 2025 | 289 | +3.6% | 80.15% | +19.26 pp | $5.00B | +32% |
| Q2 2025 | 279 | +8.1% | 60.89% | 1.48 pp | $3.80B | 2.4% |
| Q1 2025 | 258 | +7.5% | 62.37% | +9.45 pp | $3.89B | +18% |
| Q4 2024 | 240 | +19% | 52.92% | +8.99 pp | $3.30B | +20% |
| Q3 2024 | 202 | +2.5% | 43.93% | +7.22 pp | $2.74B | +20% |
| Q2 2024 | 197 | β | 36.71% | β | $2.29B | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying PTCT stock.
Based on Q1 2026 13F filings, institutional ownership of PTC Therapeutics, Inc. stands at 102.1%, held across 345 reporting institutions.
BlackRock, Inc. is the largest reported institutional holder of PTCT, with approximately 12,948,717 shares worth $0.88B as of Q1 2026.
No marquee "smart money" managers (Berkshire, Burry, ARK, Tiger Global, Pershing Square, Baupost, etc.) currently appear among the top 25 institutional holders of PTCT.
Our composite Smart Money Score for PTCT is 27 out of 100 (Bearish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
64 institutions opened new positions in PTCT during Q1 2026, while 61 fully exited. 96 added to existing positions and 183 trimmed.
PTCT institutional ownership fell by 5.96 percentage points quarter-over-quarter, with a net change of +3 holders.
The top 10 institutions account for 56.0% of all reported 13F value in PTCT, and the top 25 account for 76.0%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
PTC Therapeutics, Inc. (PTCT) Institutional Ownership