Last 47 quarters of trend data · Healthcare · Medical - Diagnostics & Research
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
Qiagen N.V.'s quarterly P/E stands at 21.6x, down 22.6% year-over-year — suggesting improving earnings relative to price. EV/EBITDA has expanded 27.5% YoY to 21.2x, reflecting rising market expectations or slowing EBITDA growth.
| Metric | TTM | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | 18.11 | 21.62 | 18.62 | 27.31 | 24.48 | 27.93 | 26.63 | — | 30.71 | 26.16 | 30.68 | 33.16 | 32.04 |
| — | -22.6% | -30.1% | — | -20.3% | +6.7% | -13.2% | — | -4.2% | -20.8% | +0.9% | +11.3% | +65.3% | |
| P/S Ratio | 3.64 | 4.32 | 4.58 | 4.91 | 4.57 | 4.79 | 5.23 | 4.73 | 5.46 | 5.06 | 5.05 | 5.39 | 5.61 |
| — | -9.8% | -12.4% | +4.0% | -16.3% | -5.4% | +3.6% | -12.4% | -2.7% | -14.7% | +0.2% | -3.4% | +17.9% | |
| P/B Ratio | 2.03 | 2.47 | 2.67 | 2.99 | 2.59 | 2.80 | 2.97 | 2.75 | 2.78 | 2.71 | 2.60 | 2.95 | 3.06 |
| — | -11.7% | -10.1% | +8.6% | -6.8% | +3.4% | +14.4% | -6.5% | -9.0% | -20.6% | -14.0% | -16.0% | -17.1% | |
| P/FCF | 16.80 | 19.93 | 20.51 | 21.74 | 23.06 | 17.60 | 19.02 | 18.36 | 26.44 | 25.99 | 28.72 | 33.22 | 81.25 |
| — | +13.2% | +7.8% | +18.4% | -12.8% | -32.3% | -33.8% | -44.7% | -67.5% | -31.6% | +110.9% | +55.1% | +359.3% | |
| EV / EBITDA | 11.81 | 21.17 | 9.99 | 16.33 | 15.09 | 16.60 | 17.66 | — | 18.44 | 17.46 | 17.78 | 19.09 | 20.86 |
| — | +27.5% | -43.4% | — | -18.2% | -5.0% | -0.7% | — | -11.6% | -14.2% | -5.1% | +3.5% | +65.2% | |
| EV / EBIT | 16.20 | 21.29 | 18.42 | 20.82 | 18.94 | 19.95 | 22.37 | — | 24.45 | 21.57 | 23.29 | 25.81 | 25.18 |
| — | +6.7% | -17.7% | — | -22.5% | -7.5% | -3.9% | — | -2.9% | -19.7% | -5.9% | +4.7% | +60.4% |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
Qiagen N.V.'s operating margin was 28.5% in Q4 2025, up 4.2 pp QoQ and up 5.6 pp YoY. This marks the 3rd consecutive quarter of margin expansion, signaling a sustained improvement in operating efficiency. The trailing four-quarter average of 24.9% lags the current quarter, suggesting the recent improvement is above-trend. Gross margin contracted 8.2% YoY, suggesting cost inflation or competitive pricing pressure.
| Metric | TTM | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 61.8% | 58.7% | 62.2% | 62.7% | 63.8% | 63.9% | 61.4% | 7.0% | 63.4% | 62.1% | 62.6% | 63.1% | 63.3% |
| — | -8.2% | +1.2% | +794.6% | +0.7% | +3.0% | -1.9% | -88.9% | +0.1% | -2.6% | -2.6% | -1.8% | -4.1% | |
| Operating Margin | 24.9% | 28.5% | 24.3% | 22.8% | 23.9% | 22.9% | 22.3% | -46.0% | 20.7% | 21.7% | 20.4% | 21.3% | 19.9% |
| — | +24.6% | +8.6% | +149.6% | +15.3% | +5.2% | +9.4% | -316.0% | +3.9% | +3.5% | +4.5% | -10.1% | -39.5% | |
| Net Margin | 20.3% | 20.0% | 24.4% | 18.0% | 18.8% | 16.9% | 19.5% | -37.0% | 17.6% | 19.2% | 16.4% | 16.3% | 17.5% |
| — | +17.7% | +25.0% | +148.8% | +6.8% | -11.7% | +19.5% | -326.4% | +0.4% | +7.5% | -0.8% | -12.9% | -29.1% |
| Metric | TTM | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | 11.6% | 2.9% | 3.6% | 2.8% | 2.6% | 2.5% | 2.8% | -5.2% | 2.2% | 2.6% | 2.1% | 2.2% | 2.4% |
| — | +16.7% | +28.5% | +153.2% | +19.5% | -4.4% | +32.9% | -332.9% | -10.0% | -0.4% | -14.7% | -24.1% | -50.6% | |
| ROA | 7.1% | 1.7% | 2.1% | 1.7% | 1.6% | 1.5% | 1.7% | -3.2% | 1.4% | 1.6% | 1.3% | 1.3% | 1.4% |
| — | +13.6% | +27.0% | +152.6% | +19.4% | -9.1% | +30.2% | -351.7% | +0.0% | +17.1% | -2.3% | -18.3% | -46.3% | |
| ROIC | 8.6% | 2.6% | 2.2% | 2.2% | 2.0% | 2.0% | 1.9% | -3.9% | 1.5% | 1.8% | 1.5% | 1.6% | 1.5% |
| — | +28.9% | +16.7% | +156.3% | +31.7% | +12.9% | +25.2% | -344.1% | +1.1% | +0.6% | -7.2% | -22.8% | -58.6% |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
Qiagen N.V.'s Debt/EBITDA ratio is 13.8x, up from 8.1x last quarter — elevated, raising questions about debt serviceability. The current ratio has improved 8.1% YoY to 3.90x, strengthening the short-term liquidity position.
| Metric | TTM | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.44 | 0.44 | 0.58 | 0.41 | 0.41 | 0.45 | 0.54 | 0.41 | 0.42 | 0.44 | 0.40 | 0.52 | 0.53 |
| — | -2.9% | +7.2% | +0.1% | -1.0% | +1.6% | +35.5% | -21.0% | -20.9% | -18.3% | -41.6% | -11.6% | -12.0% | |
| Debt / EBITDA | 2.32 | 13.79 | 8.07 | 8.43 | 8.84 | 9.77 | 11.84 | — | 10.07 | 10.42 | 10.04 | 12.06 | 12.64 |
| — | +41.1% | -31.8% | — | -12.2% | -6.2% | +18.0% | — | -20.3% | -11.9% | -35.1% | +7.5% | +69.1% | |
| Current Ratio | 3.90 | 3.90 | 2.60 | 1.61 | 3.37 | 3.61 | 2.17 | 1.77 | 1.84 | 1.99 | 3.74 | 2.36 | 2.53 |
| — | +8.1% | +19.6% | -8.8% | +82.8% | +81.2% | -41.9% | -25.2% | -27.1% | -19.0% | +103.4% | +6.0% | +15.4% | |
| Quick Ratio | 3.31 | 3.31 | 2.30 | 1.35 | 2.83 | 3.09 | 1.89 | 1.46 | 1.45 | 1.62 | 2.98 | 1.96 | 2.10 |
| — | +6.9% | +21.8% | -7.2% | +94.6% | +90.8% | -36.6% | -25.7% | -30.9% | -22.4% | +83.6% | +3.7% | +13.3% | |
| Interest Coverage | 15.74 | 11.77 | 17.39 | 17.68 | 17.39 | 12.29 | 11.14 | -19.46 | 10.94 | 10.56 | 8.67 | 8.58 | 8.53 |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Includes 30+ ratios · 47 years · Updated daily
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Quick answers to the most common questions about buying QGEN stock.
Qiagen N.V.'s current P/E is 18.1x. The average P/E over the last 4 quarters is 23.0x. Quarterly P/E ratios can vary due to seasonal revenue patterns and one-time charges.
Qiagen N.V.'s current operating margin is 24.9%. Margins have been expanding over recent quarters. Quarterly margins are particularly useful for identifying trend inflections that annual data smooths over.
Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking Qiagen N.V.'s business trajectory between earnings reports.