Shuttle Pharmaceuticals Holdings, Inc. (SHPH) P/E Ratio History
Insufficient DataInsufficient historical P/E data to classify valuation. · Data 2026–2026
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P/E Ratio Analysis
As of June 22, 2026, Shuttle Pharmaceuticals Holdings, Inc. (SHPH) trades at a price-to-earnings ratio of -0.0x, with a stock price of $3.46 and trailing twelve-month earnings per share of $-21.51.
Compared to the Healthcare sector median P/E of 22.1x, SHPH trades at a 100% discount to its sector peers. The sector includes 234 companies with P/E ratios ranging from 0.0x to 197.0x.
Relative to the broader market, SHPH trades at a notable discount to the S&P 500 median P/E of 24.4x. Investors should consider the company's growth prospects, competitive position, and earnings quality when evaluating whether the current valuation is justified.
For a comprehensive intrinsic value estimate using discounted cash flow analysis, see our SHPH DCF Valuation Calculator →
Note: P/E ratio is just one valuation metric. It does not account for balance sheet strength, cash flow quality, or growth sustainability. Always conduct comprehensive due diligence before making investment decisions.
SHPH Cross-Benchmark Valuation
How does the current P/E compare to sector peers and the broader market?
SHPH P/E vs Peers
Therapy-focused branded biopharma peers sorted by market cap
| Company | Market Cap | P/E Ratio | PEG Ratio | EPS Growth (1Y) |
|---|---|---|---|---|
| $144B | 51.7 | 2.37 | +23% | |
| $27B | 19.8Lowest | 1.14Best | +37%Best | |
| $17B | 30.5 | - | -25% |
Lower P/E can signal a discount or weaker growth expectations; PEG adds growth context.
Intrinsic Valuation
DCF models, multiple analysis, and analyst estimates.
Historical Returns
10-year return with dividends reinvested.
DCA Calculator
See how regular investing compounds over time.
Peer Comparison
Compare growth, multiples, and margins vs sector.
SHPH — Frequently Asked Questions
Quick answers to the most common questions about buying SHPH stock.
What is SHPH's P/E ratio?
Shuttle Pharmaceuticals Holdings, Inc. (SHPH) trailing twelve-month P/E ratio is -0.0x, based on TTM diluted EPS of $-21.51. The 5-year average P/E is N/A and the historical range spans N/A to N/A.
Is SHPH stock overvalued or undervalued?
SHPH current P/E: -0.0x. 5-year average P/E: N/A. Percentile: N/A.
Is SHPH stock expensive?
SHPH is fairly valued relative to its own history. The current P/E of -0.0x is near the 5-year average of N/A (N/A percentile of historical range).
What is SHPH's historical P/E range?
Over the past 5 years, SHPH's P/E ratio has ranged from N/A to N/A, with a median of N/A and an average of N/A. The current P/E of -0.0x places the stock at the N/A percentile of this range. Full historical data spans 2026–2026.
How does SHPH's P/E compare to the S&P 500?
SHPH current P/E: -0.0x. S&P 500 median P/E: 24.4x.
How does SHPH's valuation compare to Healthcare peers?
Shuttle Pharmaceuticals Holdings, Inc. P/E of -0.0x can be benchmarked against Healthcare peers in the comparison table on this page.
What is SHPH's PEG ratio?
SHPH PEG ratio is N/A, based on a P/E of -0.0x and EPS growth of 99.2%. PEG normalises P/E by growth and helps compare stocks with different earnings trajectories.
What is SHPH's earnings yield?
SHPH earnings yield is N/A, the inverse of its -0.0x P/E ratio. Earnings yield represents the percentage of each dollar invested that the company earns. It can be compared directly to bond yields to assess relative attractiveness of stocks versus fixed income.