Spyre Therapeutics, Inc. (SYRE) quarterly income statement — complete revenue, gross profit & net income history
| Metric | Q1'26 | Q4'25 | Q3'25 | Q2'25 | Q1'25 | Q4'24 | Q3'24 | Q2'24 | Q1'24 | Q4'23 | Q3'23 | Q2'23 | Q1'23 | Q4'22 | Q3'22 | Q2'22 | Q1'22 | Q4'21 | Q3'21 | Q2'21 |
|---|
| Sales/Revenue | 0 | 90.49M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 688K | 198K | 168K | 174K | 625K | 1.36M | 3.64M | 1.4M | 13.7M |
| Revenue Growth % | - | - | - | - | - | - | - | -100% | -100% | -100% | -100% | 10.08% | -85.46% | -95.39% | -87.56% | -95.44% | - | - | - | - |
| Cost of Goods Sold | 0 | 45.25M | 45.25M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 548K | 490K | 502K | 475K | 497K | 502K | 14.85M | 13.58M |
| COGS % of Revenue | - | 50% | - | - | - | - | - | - | - | - | - | - | 276.77% | 291.67% | 288.51% | 76% | 36.49% | 13.78% | 1061.69% | 99.15% |
| Gross Profit | 0 | 45.25M | -45.25M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 688K | -350K | -322K | -328K | 150K | 865K | 3.14M | -13.45M | 117K |
| Gross Margin % | - | 50% | - | - | - | - | - | - | - | - | - | 100% | -176.77% | -191.67% | -188.51% | 24% | 63.51% | 86.22% | -961.69% | 0.85% |
| Gross Profit Growth % | - | - | - | - | - | - | - | -100% | 100% | 100% | 100% | 358.67% | -140.46% | -110.25% | 97.56% | 28.21% | - | - | - | - |
| Operating Expenses | 75.64M | 102.42M | 11.64M | 41.94M | 53.57M | 61.25M | 55.39M | 44.15M | 47.77M | 45.91M | 18.34M | 159.93M | 18.46M | 18.84M | 18.43M | 22.57M | 25.31M | 23.58M | 6.84M | 6.82M |
| OpEx % of Revenue | - | 113.18% | - | - | - | - | - | - | - | - | - | 23246.22% | 9321.21% | 11214.29% | 10590.23% | 3611.68% | 1858% | 647.2% | 488.85% | 49.81% |
| Selling, General & Admin | 15.23M | 12.53M | 11.64M | 11.79M | 11.94M | 10.77M | 10.65M | 11.51M | 12.85M | 14.07M | 8.58M | 12.06M | 4.68M | 4.59M | 6.45M | 7.2M | 8.33M | 6.8M | 6.84M | 6.82M |
| SG&A % of Revenue | - | 13.85% | - | - | - | - | - | - | - | - | - | 1753.2% | 2363.64% | 2731.55% | 3706.9% | 1152% | 611.45% | 186.66% | 488.85% | 49.81% |
| Research & Development | 60.41M | 44.64M | 45.25M | 40.15M | 41.62M | 50.48M | 44.74M | 32.64M | 34.93M | 33.68M | 24.66M | 17.39M | 13.78M | 14.25M | 11.98M | 15.37M | 16.98M | 16.78M | 14.85M | 13.58M |
| R&D % of Revenue | - | 49.33% | - | - | - | - | - | - | - | - | - | 2527.03% | 6957.58% | 8482.74% | 6883.33% | 2459.68% | 1246.55% | 460.54% | 1061.69% | 99.15% |
| Other Operating Expenses | 0 | 1000K | -1000K | -1000K | 0 | 0 | 0 | 0 | 0 | -1000K | -1000K | 1000K | 0 | 0 | 0 | 0 | 0 | 0 | -1000K | -1000K |
| Operating Income | -75.64M | -57.17M | -56.89M | -41.94M | -53.57M | -61.25M | -55.39M | -44.15M | -47.77M | -45.91M | -18.34M | -159.25M | -18.81M | -19.16M | -18.75M | -22.42M | -24.44M | -20.44M | -20.29M | -6.71M |
| Operating Margin % | - | -63.18% | - | - | - | - | - | - | - | - | - | -23146.22% | -9497.98% | -11405.95% | -10778.74% | -3587.68% | -1794.49% | -560.98% | -1450.54% | -48.96% |
| Operating Income Growth % | -41.21% | 6.66% | -2.7% | 5.01% | -12.13% | -33.41% | -202.08% | 72.28% | -154.04% | -139.61% | 2.23% | -610.19% | 23.06% | 6.26% | 7.58% | -234.42% | -34.22% | 10.25% | -11.97% | 68.9% |
| EBITDA | -75.64M | -62.53M | -11.18M | -51.94M | -53.57M | -61.25M | -55.39M | -44.15M | -47.77M | -46.13M | -33.24M | -158.83M | -18.26M | -18.67M | -18.25M | -21.95M | -23.94M | -19.94M | -19.88M | -6.31M |
| EBITDA Margin % | - | -69.1% | - | - | - | - | - | - | - | - | - | -23085.76% | -9221.21% | -11114.29% | -10490.23% | -3511.68% | -1758% | -547.2% | -1421.09% | -46.05% |
| EBITDA Growth % | -41.21% | -2.08% | 79.81% | -17.64% | -12.13% | -32.77% | -66.62% | 72.2% | -161.66% | -147.08% | -82.13% | -623.66% | 23.75% | 6.36% | 8.19% | -247.99% | -34.11% | 11.01% | -11.24% | 70.44% |
| D&A (Non-Cash Add-back) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -220K | 0 | 416K | 548K | 490K | 502K | 475K | 497K | 502K | 412K | 398K |
| EBIT | -75.64M | -62.53M | -11.18M | -51.94M | -53.57M | -61.25M | -55.39M | -44.15M | -47.77M | -47.75M | -33.24M | -28.76M | -18.46M | -18.78M | -18.44M | -22.31M | -24.44M | -20.42M | -20.29M | -6.71M |
| Net Interest Income | 7M | 7.14M | 5.38M | 5.87M | 6.49M | 5.78M | 5.18M | 5.92M | 4.43M | 4.13M | 1.25M | 350K | 420K | 410K | 288K | 104K | 35K | 34K | 36K | 19K |
| Interest Income | 7M | 7.14M | 5.38M | 5.87M | 6.49M | 5.78M | 5.18M | 5.92M | 4.43M | 4.13M | 1.25M | 350K | 420K | 410K | 288K | 104K | 35K | 34K | 36K | 19K |
| Interest Expense | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Income/Expense | 6.64M | -5.36M | 45.7M | 5.22M | 8.78M | 4.96M | -13.62M | 5.31M | 3.95M | -17.27M | -21.77M | -57.83M | 348K | 378K | 312K | 109K | 5K | 19K | 12K | -33K |
| Pretax Income | -69M | -62.53M | -11.18M | -36.72M | -44.79M | -56.3M | -69.01M | -38.84M | -43.83M | -63.18M | -40.1M | -217.07M | -18.46M | -18.78M | -18.44M | -22.31M | -24.44M | -20.42M | -20.28M | -6.74M |
| Pretax Margin % | - | -69.1% | - | - | - | - | - | - | - | - | - | -31551.45% | -9322.22% | -11180.95% | -10599.43% | -3570.24% | -1794.13% | -560.46% | -1449.68% | -49.2% |
| Income Tax | 0 | 0 | 0 | 0 | -15K | 1K | 18K | 0 | 32K | 0 | 3K | 7K | -36K | 38K | -209K | 9K | 0 | 23K | 26K | 92K |
| Effective Tax Rate % | 0% | 0% | 0% | 0% | 0.03% | -0% | -0.03% | 0% | -0.07% | 0% | -0.01% | -0% | 0.2% | -0.2% | 1.13% | -0.04% | 0% | -0.11% | -0.13% | -1.37% |
| Net Income | -69M | -62.53M | -11.18M | -36.72M | -44.77M | -56.3M | -69.03M | -38.84M | -43.86M | -63.18M | -40.11M | -217.08M | -18.42M | -18.82M | -18.23M | -22.32M | -24.44M | -20.45M | -20.31M | -6.83M |
| Net Margin % | - | -69.1% | - | - | - | - | - | - | - | - | - | -31552.47% | -9304.04% | -11203.57% | -10479.31% | -3571.68% | -1794.13% | -561.09% | -1451.54% | -49.87% |
| Net Income Growth % | -54.12% | -11.07% | 83.8% | 5.46% | -2.09% | 10.9% | -72.11% | 82.11% | -138.07% | -235.67% | -119.96% | -872.45% | 24.61% | 7.94% | 10.21% | -226.84% | -34.13% | 9.98% | -12.61% | 68.11% |
| Net Income (Continuing) | -69M | -62.53M | -11.18M | -36.72M | -44.77M | -56.3M | -69.03M | -38.84M | -43.86M | -63.18M | -40.11M | -217.08M | -18.42M | -18.82M | -18.23M | -22.32M | -24.44M | -20.45M | -20.31M | -6.83M |
| Discontinued Operations | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| EPS (Diluted) | -0.74 | -0.70 | -0.15 | -0.60 | -0.13 | -0.15 | -1.36 | -0.86 | -1.20 | -2.91 | -9.34 | -56.79 | -4.89 | -7.20 | -4.84 | -6.79 | -9.26 | -10.36 | -7.72 | -2.60 |
| EPS Growth % | -469.23% | -366.67% | 88.97% | 30.23% | 89.17% | 94.85% | 85.44% | 98.49% | 75.46% | 59.58% | -92.98% | -736.38% | 47.19% | 30.5% | 37.31% | -161.15% | -33.43% | -5.5% | -6.63% | 74.28% |
| EPS (Basic) | -0.74 | -0.69 | -0.15 | -0.60 | -0.13 | -0.15 | -1.36 | -0.86 | -1.20 | -2.91 | -9.34 | -56.79 | -4.89 | -7.20 | -4.84 | -6.79 | -9.26 | -10.36 | -7.72 | -2.60 |
| Diluted Shares Outstanding | 346.05M | 346.05M | 60.41M | 60.7M | 60.27M | 47.03M | 50.89M | 45.32M | 36.51M | 21.7M | 4.29M | 3.82M | 3.77M | 2.61M | 3.77M | 3.29M | 2.64M | 1.97M | 2.63M | 2.63M |
| Basic Shares Outstanding | 346.05M | 346.05M | 74.93M | 60.7M | 60.27M | 47.03M | 50.89M | 45.32M | 36.51M | 21.7M | 4.29M | 3.82M | 3.77M | 2.61M | 3.77M | 3.29M | 2.64M | 1.97M | 2.63M | 2.63M |
| Dividend Payout Ratio | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |