Cash flow remains erratic, evidenced by a 2026Q1 OCF/NI ratio of -0.90 and a $100 million share repurchase program that occurred despite the company reporting a negative $17.9 million free cash flow.
| Metric | TTM | Dec'25 | Dec'24 | Dec'23 | Dec'22 | Dec'21 | Dec'20 | Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 | Dec'09 | Dec'08 | Dec'07 | Dec'06 | Dec'05 | Dec'04 | Dec'03 | Dec'02 | Dec'01 | Dec'00 | Dec'99 | Dec'98 | Dec'97 | Dec'96 |
|---|
| Cash from Operations | -13.95M | -24.77M | -40.52M | -31.41M | -176.17M | -295.63M | -214.51M | -132.81M | -128.93M | -93.76M | -61.59M | -44.69M | -35.06M | -10.82M | -5.19M | -86.58K | -1.97M | -1.05M | -4.44M | -10.23M | -7.75M | -6.24M | -5.69M | -3.45M | -1.43M | -4.47M | -1.15M | -2.3M | -2.6M | -4.1M | -4M |
| Operating CF Margin % | - | -4.02% | -12.31% | -13.44% | -6325.67% | -4419.7% | -141123.03% | -87372.37% | -84819.08% | -61532.32% | -40419.3% | -29327.98% | -23008.06% | -7103.4% | -27236.27% | - | - | - | - | - | - | - | - | - | -286.51% | -164.99% | -21.52% | -191.67% | -86.67% | -4100% | -4000% |
| Operating CF Growth % | 158.98% | 38.86% | -28.98% | 82.17% | 40.41% | -37.82% | -61.52% | -3.01% | -37.5% | -52.23% | -37.82% | -27.47% | -223.9% | -108.64% | -5892.31% | 95.61% | -87.67% | 76.38% | 56.56% | -31.98% | -24.11% | -9.74% | -64.87% | -140.93% | 67.98% | -288.05% | 49.87% | 11.54% | 36.59% | -2.5% | - |
| Net Income | 461.9M | 447.18M | 23.38M | 12.67M | -198.34M | -348.1M | -279.38M | -172.87M | -173.48M | -118.48M | -78.25M | -62.95M | -55.78M | -20.48M | -26.18M | -889.07K | 623.64K | -2.79M | -4.27M | -12.03M | -9.7M | -19.14M | -5.9M | -5.96M | -1.55M | -1.73M | -5.8M | -2.4M | -2.8M | -5.2M | -3.6M |
| Depreciation & Amortization | 7.72M | 59K | 280K | 423K | 515K | 494K | 374K | 282K | 88K | 82.36K | 62.96K | 15.45K | 3.93K | 1.13K | 235 | 0 | 3.4K | 5.53K | 26.11K | 48.34K | 60.19K | 53.73K | 128.14K | 189.25K | 49.5K | 66.23K | 76.09K | 100K | 200K | 100K | 0 |
| Stock-Based Compensation | 49.7M | 64.67M | 42.54M | 37.93M | 19.18M | 61.27M | 80.29M | 11.34M | 12.89M | 15.95M | 7.51M | 15.7M | 21.11M | 5.2M | 3.42M | 86.49K | 217.48K | 353.44K | 463.89K | 1.68M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Deferred Taxes | 22.49M | -348M | 0 | 0 | 0 | 517K | -30K | -257K | -119K | 61.32K | 5.84B | 5.84B | 10.01M | 10.01M | 289K | 0 | 352.66K | 500K | 250K | -1.68M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | -340M | 5.86M | 2.58M | 2.22M | 4.11M | 2.4M | 4M | 3.52M | 3.94M | 58.74K | -5.84B | -5.84B | -4.35M | -9.63M | 16.58M | 297K | -3.36M | 1.1M | 56.9K | 1.76M | 1.68M | 11.8M | -66.59K | 2.46M | 12.89K | -763.71K | 2.9M | 100K | 100K | 900K | 200K |
| Working Capital Changes | -215.76M | -194.54M | -109.3M | -84.66M | -1.65M | -12.22M | -19.76M | 25.19M | 27.76M | 8.56M | 8.77M | 2.07M | -6.05M | 4.07M | 705.57K | 419K | 195.69K | -218.73K | -972.05K | -2.93K | 207.7K | 1.04M | 144.03K | -141.97K | 51.98K | -2.04M | 1.67M | -100K | -100K | 100K | -600K |
| Change in Receivables | -201.93M | -176.44M | -78.09M | -51.09M | 1.39M | -1.39M | -6K | -11K | 14K | -24.62K | 102.17K | -100.5K | 0 | 0 | 0 | 0 | -244.48K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Inventory | -422K | -33.45M | -66.85M | -36.94M | 0 | -15.99M | 6K | 11K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Payables | 24.31M | 55.88M | 0 | 192K | -11.01M | 15.99M | 11.63M | -4.79M | 10.96M | 11.02M | 6.49M | 5.47M | -603.38K | 4.03M | 595.76K | 0 | 0 | -326.9K | -737.19K | -224.19K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Cash from Investing | 16.87M | 13.8M | -1.04M | -50.65M | -20.01M | -332K | -24.51M | -718K | 1.18M | -8.21M | 26.55M | -24.69M | -18.36M | -4.93M | -1.4K | 10.39K | 516.52K | 0 | -8.97K | -9.13K | 968.78K | 3.47M | -4.21M | 160.64K | -5.46K | 2.89M | -317.97K | -100K | -200K | -200K | -100K |
| Capital Expenditures | -240K | -214K | -45K | 0 | -14K | -401K | -357K | -131K | -90K | -2.23K | -343.99K | -42.22K | -18.57K | -5.68K | -1.4K | 0 | -2.84K | 0 | -8.97K | -9.13K | -37.05K | -39.55K | -138.34K | -6.55K | -5.46K | -108.25K | -171.35K | -100K | -200K | -200K | -100K |
| CapEx % of Revenue | 0.03% | 0.03% | 0.01% | - | 0.5% | 5.99% | 234.87% | 86.18% | 59.21% | 1.46% | 225.74% | 27.7% | 12.19% | 3.73% | 7.34% | - | - | - | - | - | - | - | - | - | 1.09% | 3.99% | 3.2% | 8.33% | 6.67% | 200% | 100% |
| Acquisitions | 0 | 0 | 0 | 0 | 20M | -69K | 24.15M | 587K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10.39K | 519.37K | 0 | 0 | -1.01M | 0 | 6.78K | 0 | -32.81K | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Other Investing | 14.2M | 0 | 0 | 0 | -20M | 69K | -24.15M | -587K | 1.27M | -8.21M | 26.89M | -24.64M | -18.34M | -4.92M | 0 | 0 | 0 | 0 | 0 | -1K | 0 | 0 | 0 | 200K | 0 | 3M | 0 | 0 | 0 | 0 | 0 |
| Cash from Financing | 307.2M | -89.73M | 128.53M | 72.7M | -391K | 41.42M | 679.83M | 204.21M | 113.64M | 133.66M | 5.02M | 68.72M | 68.64M | 39.78M | 11.9M | 9.82M | 1.91M | 961.77K | 3.91M | 7.86M | -15.26K | 11.7M | 3.39M | 8.98M | -37.44K | 510.79K | 661.28K | 0 | 100K | 10.6M | 1.3M |
| Debt Issued (Net) | 490.06M | 0 | 137.26M | 25M | -975K | 40M | 0 | 29.99M | 0 | 0 | 0 | 0 | -677.78K | 0 | -200K | 0 | 0 | 434.77K | 1.06M | 0 | 0 | -651.4K | 0 | -806K | 778.5K | 0 | 0 | 0 | 0 | 0 | -200K |
| Equity Issued (Net) | -183.29M | -89.73M | -8.76M | 46.3M | 584K | 2.22M | 679.68M | 175.02M | 113.64M | 133.66M | 5.03M | 67.76M | 65.61M | 39.78M | 12.17M | 9.82M | 2.16M | 0 | 0 | 7.86M | -15.26K | 12.35M | 3.39M | 9.79M | 1.7M | 1.32M | 661.28K | 0 | 100K | 10.6M | 1.5M |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1.3K | 0 | 0 | -807 | -987 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | -185.11M | -91.24M | -8.76M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -149.8K | -84.54K | 0 | 0 | 0 | 0 | 0 | -15.26K | 0 | 0 | -300 | 0 | -617.07K | -511.81K | 0 | 0 | 0 | 0 |
| Other Financing | 432K | 0 | 25K | 1.41M | 0 | -800K | 147K | -795K | 0 | 0 | -13.47K | 963.17K | 3.71M | 0 | -75.9K | 0 | -249.22K | 527K | 2.85M | 0 | 0 | 0 | -1.29K | 0 | -2.52M | -811.11K | 0 | 0 | 0 | 0 | 0 |
| Net Change in Cash | 310.11M | -100.7M | 86.97M | -9.36M | -196.57M | -254.55M | 440.81M | 70.69M | -14.11M | 31.69M | -30.03M | -652.46K | 15.23M | 24.03M | 6.71M | 9.75M | 460.67K | -88.03K | -543.66K | -2.38M | -6.8M | 8.92M | -6.51M | 5.69M | -1.48M | -1.07M | -809.74K | -2.3M | -2.7M | 6.3M | -2.8M |
| Free Cash Flow | -14.19M | -24.99M | -40.56M | -31.41M | -176.18M | -296.04M | -214.86M | -132.94M | -129.01M | -93.77M | -61.94M | -44.73M | -35.08M | -10.83M | -5.19M | -86.58K | -1.97M | -1.05M | -4.45M | -10.24M | -7.79M | -6.28M | -5.83M | -3.46M | -1.44M | -4.58M | -1.32M | -2.4M | -2.8M | -4.3M | -4.1M |
| FCF Margin % | -2.03% | -4.05% | -12.33% | -13.44% | -6326.18% | -4425.7% | -141357.89% | -87458.55% | -84878.29% | -61533.78% | -40645.04% | -29355.69% | -23020.25% | -7107.13% | -27243.61% | - | - | - | - | - | - | - | - | - | -287.61% | -168.98% | -24.71% | -200% | -93.33% | -4300% | -4100% |
| FCF Growth % | 76.77% | 38.4% | -29.12% | 82.17% | 40.49% | -37.78% | -61.63% | -3.04% | -37.59% | -51.39% | -38.46% | -27.52% | -223.9% | -108.69% | -5893.93% | 95.61% | -87.94% | 76.42% | 56.51% | -31.47% | -23.92% | -7.82% | -68.56% | -140.47% | 68.62% | -246.01% | 44.82% | 14.29% | 34.88% | -4.88% | - |
| FCF per Share | -0.09 | -0.15 | -0.25 | -0.21 | -1.30 | -2.24 | -1.86 | -1.50 | -1.71 | -1.51 | -1.26 | -0.98 | -1.03 | -0.43 | -0.40 | -0.04 | -49.60 | -41.81 | -177.33 | -423.39 | -364.38 | -405.92 | -608.62 | -434.43 | -323.22 | -4037.55 | -3044.59 | -7017.54 | -8750.00 | -19724.77 | -19806.76 |
| FCF Conversion (FCF/Net Income) | -0.03x | -0.06x | -1.73x | -2.48x | 0.79x | 0.85x | 0.77x | 0.77x | 0.74x | 0.79x | 0.79x | 0.71x | 0.63x | 0.53x | 0.29x | 0.10x | -3.16x | 0.38x | 1.04x | 0.85x | 0.80x | 0.33x | 0.97x | 0.58x | 0.93x | 2.58x | 0.20x | 0.96x | 0.93x | 0.79x | 1.11x |
| Interest Paid | 12.2M | 0 | 18.47M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 1.96M | 0 | 500K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Persistent negative operating cash
As reported in financial statements, TGTX exhibits a persistent disconnect between net income and operating cash flow, evidenced by a 2026Q1 OCF/NI ratio of -0.90, which suggests that reported accounting profits are not currently translating into the actual cash generation required for long-term operational sustainability.
The consistent failure of net income to convert into positive operating cash flow indicates that the company's profitability is heavily reliant on non-cash items or accounting adjustments. Investors should monitor whether this divergence narrows as the Briumvi launch matures, as current trends suggest the core business remains cash-consumptive despite headline earnings.
Based on TGTX's reported figures, the free cash flow trajectory remains highly erratic, with a negative FCF margin of 8.8% in 2026Q1, highlighting the company's ongoing struggle to achieve self-sustaining cash flow despite the successful commercialization of its primary neurology asset in the US market.
The volatility in FCF, punctuated by occasional positive quarters, appears to be driven more by timing differences in working capital than by consistent operational efficiency. This pattern suggests that the company's cash flow profile is not yet stabilized, leaving it exposed to liquidity risks if revenue growth fails to outpace rising commercial costs.
According to recent SEC filings, TGTX has faced significant cash outflows related to working capital, including a $69.8 million drain in 2026Q1, which underscores the heavy burden of managing inventory and receivables during the aggressive scaling phase of its national commercial launch for Briumvi.
The recurring negative working capital changes suggest that the company is likely building inventory or extending payment terms to support its market penetration strategy. This aggressive use of cash to fuel growth warrants further investigation into whether these investments will yield the expected long-term persistence in patient adoption.
As indicated by historical data, TGTX has utilized cash for share repurchases, including $100 million in 2026Q1, even while operating cash flow remained negative, a strategy that appears to prioritize capital return over the preservation of liquidity for essential R&D and commercial expansion efforts.
This capital deployment strategy may indicate management's confidence in the Briumvi franchise, yet it simultaneously depletes the cash reserves necessary to navigate potential regulatory or competitive headwinds. Investors should consider whether such aggressive buybacks are premature given the company's ongoing reliance on external financing to fund its operations.
Quick answers to the most common questions about buying TGTX stock.
TG Therapeutics, Inc. (TGTX) generated $-24.8M in net cash from operating activities in 2025. This reflects the cash generated directly from core business operations.
TG Therapeutics, Inc. (TGTX) reported negative free cash flow of $25.0M in 2025, indicating capital requirements exceeded cash from operations.
TG Therapeutics, Inc. (TGTX) spent $0.2M on capital expenditures in 2025. CapEx represents the cash invested in physical assets like property, plant, and equipment to maintain or grow the business.
In 2025, TG Therapeutics, Inc. (TGTX) spent $91.2M on share repurchases. This shows the company's commitment to returning capital to its equity investors.