Ranked by reported Q2 2026 13F market value
Share of total reported institutional value in TGTX held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | BlackRock, Inc. | 22.1M | $1.21B | -0.9% | 14.404% | 0.02% |
| 2 | VANGUARD PORTFOLIO MANAGEMENT LLC | 8.0M | $437.5M | -3.8% | 5.202% | 0.02% |
| 3 | STATE STREET CORP | 7.8M | $427.8M | -10.0% | 5.086% | 0.01% |
| 4 | VANGUARD CAPITAL MANAGEMENT LLC | 6.1M | $337.8M | -6.9% | 4.017% | 0.01% |
| 5 | GEODE CAPITAL MANAGEMENT, LLC | 3.6M | $200.1M | +4.1% | 2.379% | 0.01% |
| 6 | D. E. Shaw & Co., Inc. | 3.5M | $191.1M | +474.7% | 2.272% | 0.09% |
| 7 | Soleus Capital Management, L.P. | 2.9M | $160.9M | -27.3% | 1.913% | 5.54% |
| 8 | Clearbridge Investments, LLC | 2.7M | $145.6M | -17.5% | 1.731% | 0.12% |
| 9 | CONGRESS ASSET MANAGEMENT CO | 2.6M | $142.9M | +19.9% | 1.699% | 0.88% |
| 10 | TWO SIGMA INVESTMENTS, LP | 2.5M | $137.7M | +62.5% | 1.638% | 0.10% |
| 11 | JANE STREET GROUP, LLC | 2.4M | $129.7M | -25.1% | 1.542% | 0.01% |
| 12 | GOLDMAN SACHS GROUP INC | 2.3M | $127.1M | -24.8% | 1.512% | 0.01% |
| 13 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1.9M | $106.0M | -3.2% | 1.260% | 0.01% |
| 14 | Pictet Asset Management Holding SA | 1.8M | $98.1M | +2.2% | 1.167% | 0.09% |
| 15 | Nuveen, LLC | 1.6M | $89.3M | +12.4% | 1.062% | 0.02% |
| 16 | MORGAN STANLEY | 1.6M | $88.0M | +13.7% | 1.046% | 0.00% |
| 17 | Hood River Capital Management LLC | 1.6M | $87.9M | +2.0% | 1.046% | 0.64% |
| 18 | NORTHERN TRUST CORP | 1.5M | $84.4M | +6.6% | 1.004% | 0.01% |
| 19 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1.3M | $72.1M | +1.4% | 0.858% | 0.01% |
| 20 | BANK OF AMERICA CORP /DE/ | 1.3M | $72.0M | -10.4% | 0.856% | 0.00% |
| 21 | CITADEL ADVISORS LLC | 1.2M | $68.2M | -49.2% | 0.810% | 0.00% |
| 22 | DIMENSIONAL FUND ADVISORS LP | 1.2M | $66.5M | +11.6% | 0.791% | 0.01% |
| 23 | FMR LLC | 1.0M | $56.0M | +263.3% | 0.665% | 0.00% |
| 24 | VANGUARD FIDUCIARY TRUST CO | 962K | $52.8M | -0.7% | 0.628% | 0.01% |
| 25 | BARCLAYS PLC | 958K | $52.6M | +721.1% | 0.626% | 0.01% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in TGTX — a direct measure of their conviction.
Filings activity in TGTX during Q2 2026, grouped by how each filer changed its position.
Institutions that opened a new TGTX position in Q2 2026
Institutions that fully closed their TGTX position in Q2 2026
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q2 2026 | 435 | +20% | 75.23% | +3.63 pp | $6.08B | +70% |
| Q1 2026 | 364 | +4.3% | 71.60% | +2.61 pp | $3.59B | +13% |
| Q4 2025 | 349 | +1.7% | 68.99% | +3.01 pp | $3.16B | 13% |
| Q3 2025 | 343 | 0.6% | 65.98% | +0.54 pp | $3.62B | +1.5% |
| Q2 2025 | 345 | 3.9% | 65.44% | +2.65 pp | $3.57B | 6.7% |
| Q1 2025 | 359 | +12% | 62.79% | 1.32 pp | $3.83B | +22% |
| Q4 2024 | 321 | +8.8% | 64.11% | 2.17 pp | $3.13B | +32% |
| Q3 2024 | 295 | — | 66.28% | — | $2.37B | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying TGTX stock.
Based on Q2 2026 13F filings, institutional ownership of TG Therapeutics, Inc. stands at 75.2%, held across 435 reporting institutions.
BlackRock, Inc. is the largest reported institutional holder of TGTX, with approximately 22,050,045 shares worth $1.21B as of Q2 2026.
Yes — 4 widely-followed marquee investors appear among the top 25 institutional holders of TGTX, including TWO SIGMA INVESTMENTS, LP, JANE STREET GROUP, LLC, SUSQUEHANNA INTERNATIONAL GROUP, LLP, CITADEL ADVISORS LLC.
Our composite Smart Money Score for TGTX is 83 out of 100 (Strong Smart Money). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
101 institutions opened new positions in TGTX during Q2 2026, while 32 fully exited. 292 added to existing positions and 31 trimmed.
TGTX institutional ownership rose by 3.63 percentage points quarter-over-quarter, with a net change of +71 holders.
The top 10 institutions account for 55.8% of all reported 13F value in TGTX, and the top 25 account for 76.3%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.