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TRVITrevi Therapeutics, Inc.
$14.33$2.0B
Overview & Tools
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TRVI logo

Trevi Therapeutics, Inc.

TRVI
NASDAQ · Neuroscience Biotech
$14.33
At close - Nov 6, 4:00 PM EST - USD
Market Cap$2.03B
P/E-43.9x
52W High$20.22
Volume2.53M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q2

R&D Surge Extends Cash Runway Amid Dilution

Trevi Therapeutics is a pre-revenue biotech advancing a clinical pipeline, with R&D spend accelerating 54% quarter-over-quarter to $15.2M in 2026Q2, signaling intensified trial activity. A $135M equity raise bolstered cash to $54.3M, extending runway despite a $17.6M quarterly FCF burn.

GrowthMixed
ProfitabilityNegative
ValuationReview
TechnicalsWeak
Explore valuation models
MARKET ACTION

TRVI price & volume

Price trend, volume and key moving averages

Launch Terminal
Loading chart...
Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

7/12 Beats

EPS beat 7 of last 12 quarters

02

Valuation risk

-229% Peers

P/E is 229% below peer median

03

Market leadership

RS 52 · Avg

Average momentum (RS Rating: 52)

04

Weak Trend

Below 200DMA

Price < 200DMA

Next CatalystConfirmed earnings · Nov 9

Market performance

Price History →

Trailing total returns as of 11/8/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
TRVI+20.52%
S&P 500 (^GSPC)+7.63%
1-Year Return
TRVI+30.15%
S&P 500 (^GSPC)+9.69%
3-Year Return
TRVI+895.14%
S&P 500 (^GSPC)+104.59%
5-Year Return
TRVI+1074.59%
S&P 500 (^GSPC)+84.59%

Growth & profitability

Annual revenue & EPS trend
Revenue FY25
-
Net income FY25
-$43M+10.8% YoY
Free cash flow FY25
-$42M-10.0% YoY
Operating margin FY25
-
ROIC (FY25)-31.9%
Avg ROIC 5Y-43.9%
ROE (TTM)-23.6%
Piotroski Score4 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate7/12 (58%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Aug 6, 2026
-$0.11-0.5%
vs -$0.11
—
vs —
Q2 2026
May 5, 2026
-$0.09-28.6%
vs -$0.07
—
vs —
Q2 2026
Mar 17, 2026
-$0.06+40.0%
vs -$0.10
—
vs —
Q4 2025
Nov 13, 2025
-$0.08+20.0%
vs -$0.10
—
vs —
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

4 Stories
GlobeNewsWire·5d ago
Trevi Therapeutics to Report Third Quarter 2026 Financial Results and Provide a Corporate Update on November 9, 2026

NEW HAVEN, Conn., Nov. 02, 2026 (GLOBE NEWSWIRE) -- Trevi Therapeutics, Inc. (Nasdaq: TRVI), a clinical-stage biopharmaceutical company developing the investigational therapy Haduvio™ (oral nalbuphine ER) for the treatment of chronic cough in patients with idiopathic pulmonary fibrosis (IPF), non-IPF interstitial lung disease (non-IPF ILD), and refractory chronic cough (RCC), today announced that senior management will host a conference call and live audio webcast on Monday, November 9, 2026, at 4:30 p.m.

GlobeNewsWire·Oct 27, 2026
Trevi Therapeutics to Participate in Stifel's 2026 Healthcare Conference

Fireside chat with management on Wednesday, November 11, 2026, at 10:00 a.m. ET Fireside chat with management on Wednesday, November 11, 2026, at 10:00 a.m. ET

GlobeNewsWire·Oct 13, 2026
Trevi Therapeutics Announces Oral Presentation Accepted at the CHEST 2026 Annual Meeting

Professor Philip Molyneaux will present on the patient-reported outcomes from the Phase 2b CORAL trial of nalbuphine ER for the treatment of chronic cough in patients with idiopathic pulmonary fibrosis (IPF) Professor Philip Molyneaux will present on the patient-reported outcomes from the Phase 2b CORAL trial of nalbuphine ER for the treatment of chronic cough in patients with idiopathic pulmonary fibrosis (IPF)

Seeking Alpha·Sep 16, 2026
Trevi Therapeutics, Inc. (TRVI) Presents at Morgan Stanley 24th Annual Global Healthcare Conference Transcript

Trevi Therapeutics, Inc. (TRVI) Presents at Morgan Stanley 24th Annual Global Healthcare Conference Transcript

Filtered for Trevi Therapeutics, Inc.More Headlines
04

Compare before deciding

Benchmark TRVI against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Trevi Therapeutics, Inc. (TRVI)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
TRVI logoTRVITrevi Therapeutics, Inc.Current
$14.33$2.03B-43.92——-23.59%—
IDYA logoIDYAIDEAYA Biosciences, Inc.
$31.24$2.74B-7.663024.43%-1149.62%-39.52%—
PTCT logoPTCTPTC Therapeutics, Inc.
$65.44$5.43B-51.55114.51%-9.17%——
ACAD logoACADACADIA Pharmaceuticals Inc.
$21.23$3.64B10.2811.87%30.13%28.03%—
INVA logoINVAInnoviva, Inc.
$19.10$1.41B7.1218.52%43.79%15.84%—
PRAX logoPRAXPraxis Precision Medicines, Inc.
$277.62$7.74B-23.85-100%—-34.15%—

Compare TRVI vs Peers

Trevi Therapeutics, Inc. (TRVI) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs IDYA

Most directly comparable listed peer for TRVI.

Scale Benchmark

vs IQV

Larger-name benchmark to compare TRVI against a more recognizable public peer.

Peer Set

Compare Top 5

vs IDYA, PTCT, ACAD, INVA

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

TRVI SEC Filings & Documents

Trevi Therapeutics, Inc. (TRVI) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Aug 6, 2026·SEC

Material company update

Jun 4, 2026·SEC

Material company update

May 5, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 17, 2026·SEC

FY 2025

Mar 18, 2025·SEC

FY 2024

Mar 20, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Aug 6, 2026·SEC

FY 2026

May 5, 2026·SEC

FY 2025

Nov 13, 2025·SEC

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TRVI Frequently Asked Questions

Trevi Therapeutics, Inc. (TRVI) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is TRVI profitable?

No. Trevi Therapeutics, Inc. (TRVI) reported a net loss of $51.1M over the trailing twelve months.

Dividend & Returns
What is TRVI's return on equity?

Trevi Therapeutics, Inc. (TRVI) had a return on equity (ROE) of -23.6% over the trailing twelve months. A negative ROE means the company lost money over the period.

What is Trevi Therapeutics, Inc.'s free cash flow?

Trevi Therapeutics, Inc. (TRVI) had negative free cash flow of $39.4M over the trailing twelve months.

What if you invested $1,000 in TRVI back in 2016?

Total return calculator · dividends reinvested · 10+ years of data

See returns →