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TRVITrevi Therapeutics, Inc.
$17.21$2.4B
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TRVI logoTrevi Therapeutics, Inc.(TRVI)Earnings, Financials & Key Ratios

TRVI•NASDAQ
Price updated Jun 19, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryNeuroscience and Psychiatry Therapies
AboutTrevi Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of Haduvio to treat serious neurologically mediated conditions. The company is developing Haduvio, an oral extended-release formulation of nalbuphine, which is in phase IIb/III clinical trial for the treatment of chronic pruritus, chronic cough in patients with idiopathic pulmonary fibrosis. It has a license agreement with Endo Pharmaceuticals Inc. to develop and commercialize products incorporating nalbuphine hydrochloride in any formulation. The company was incorporated in 2011 and is headquartered in New Haven, Connecticut.Show more
  • Revenue$0
  • EBITDA-$49M+4.3%
  • Net Income-$43M+10.8%
  • EPS (Diluted)-0.29+38.3%
  • ROE-30.23%+42.5%

TRVI Key Insights

Trevi Therapeutics, Inc. (TRVI) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Company is almost debt free
  • ✓Momentum leader: RS Rating 88 (top 12%)
  • ✓Trading near 52-week high

✗Weaknesses

  • ✗Shares diluted 43.6% in last year
  • ✗Expensive at 13.6x book value
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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TRVI Price & Volume

Trevi Therapeutics, Inc. (TRVI) stock price & volume — 10-year historical chart

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TRVI Growth Metrics

Trevi Therapeutics, Inc. (TRVI) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM3.67%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM28.06%

Return on Capital

10 Years-116.35%
5 Years-53.3%
3 Years-41.95%
Last Year-34.73%

TRVI Recent Earnings

Trevi Therapeutics, Inc. (TRVI) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 8/12 qtrs (67%)
Q2 2026Latest
May 5, 2026
Metric
Actual
Est
EPS
$0.09-28.6%
$0.07
Rev
—
—
Q2 2026
Mar 17, 2026
Metric
Actual
Est
EPS
$0.06+40.0%
$0.10
Rev
—
—
Q4 2025
Nov 13, 2025
Metric
Actual
Est
EPS
$0.08+20.0%
$0.10
Rev
—
—
Q3 2025
Aug 7, 2025
Metric
Actual
Est
EPS
$0.09+10.0%
$0.10
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 5, 2026
$0.09vs $0.07-28.6%
—
Q2 2026Mar 17, 2026
$0.06vs $0.10+40.0%
—
Q4 2025Nov 13, 2025
$0.08vs $0.10+20.0%
—
Q3 2025Aug 7, 2025
$0.09vs $0.10+10.0%
—
Based on last 12 quarters of dataView full earnings history →

TRVI Peer Comparison

Trevi Therapeutics, Inc. (TRVI) competitors in Neuroscience and Psychiatry Therapies — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
IDYA logoIDYAIDEAYA Biosciences, Inc.Direct Competitor2.74B31.23-24.4030.24%-62.17%-13.96%0.03
PTCT logoPTCTPTC Therapeutics, Inc.Direct Competitor6.55B78.9810.15114.51%-22.58%
ACAD logoACADACADIA Pharmaceuticals Inc.Direct Competitor3.7B21.629.4411.87%34.3%35.65%0.04
INVA logoINVAInnoviva, Inc.Direct Competitor1.66B22.496.8218.52%118.91%47.59%0.23
PRAX logoPRAXPraxis Precision Medicines, Inc.Direct Competitor8.15B282.31-20.94-100%-43.02%0.00
NKTR logoNKTRNektar TherapeuticsDirect Competitor1.19B60.98-6.27-43.89%-284.18%-87%1.66
AXSM logoAXSMAxsome Therapeutics, Inc.Product Competitor12.89B250.50-68.0765.55%-26.59%-260.01%2.73
CRL logoCRLCharles River Laboratories International, Inc.Supply Chain8.91B185.00-63.57-0.85%-4.59%-5.66%0.95

Compare TRVI vs Peers

Trevi Therapeutics, Inc. (TRVI) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs IDYA

Most directly comparable listed peer for TRVI.

Scale Benchmark

vs IQV

Larger-name benchmark to compare TRVI against a more recognizable public peer.

Peer Set

Compare Top 5

vs IDYA, PTCT, ACAD, INVA

TRVI Income Statement

Trevi Therapeutics, Inc. (TRVI) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
0000000000
Revenue Growth %
----------
Cost of Goods Sold
023K39K47K0000034K
COGS % of Revenue
----------
Gross Profit
0▲ 0%
-23K▲ 0%
-39K▼ 69.6%
-47K▼ 20.5%
0▲ 100.0%
0▲ 0%
0▲ 0%
0▲ 0%
0▲ 0%
-34K▲ 0%
Gross Margin %
----------
Gross Profit Growth %
100%--69.57%-20.51%100%-----
Operating Expenses
8.24M18.41M26.64M32.49M32.48M29.91M33.92M51.52M49.33M52.77M
OpEx % of Revenue
----------
Selling, General & Admin
2.14M4.34M7.31M10.16M9.49M10.07M10.24M12.15M15.85M17.16M
SG&A % of Revenue
----------
Research & Development
6.09M14.07M19.34M22.33M22.98M19.83M23.68M39.38M33.48M35.61M
R&D % of Revenue
----------
Other Operating Expenses
-24K000000000
Operating Income
-8.24M▲ 0%
-18.41M▼ 123.5%
-26.64M▼ 44.7%
-32.49M▼ 21.9%
-32.48M▲ 0.0%
-29.91M▲ 7.9%
-33.92M▼ 13.4%
-51.52M▼ 51.9%
-49.33M▲ 4.3%
-52.77M▲ 0%
Operating Margin %
----------
Operating Income Growth %
4.5%-123.48%-44.75%-21.93%0.04%7.91%-13.43%-51.89%4.26%-
EBITDA
-8.23M-18.39M-26.61M-32.44M-32.43M-29.86M-33.8M-51.38M-49.18M-52.63M
EBITDA Margin %
----------
EBITDA Growth %
4.5%-123.31%-44.72%-21.93%0.05%7.9%-13.18%-52%4.27%-3.32%
D&A (Non-Cash Add-back)
4K23K39K47K50K43K123K147K144K141K
EBIT
-8.24M-20.5M-26.64M-32.32M-32.76M-28.02M-28.71M-47.94M-42.82M-47.38M
Net Interest Income
-3.27M-18K792K-278K-1.19M960K4.36M3.6M6.54M7.11M
Interest Income
69K156K792K178K10K1.74M4.75M3.6M6.54M7.11M
Interest Expense
3.34M174K0456K1.2M780K391K4K00
Other Income/Expense
-4.65M-2.26M577K-287K-1.49M719K4.83M3.58M6.5M7.09M
Pretax Income
-12.89M▲ 0%
-20.67M▼ 60.4%
-26.07M▼ 26.1%
-32.78M▼ 25.7%
-33.96M▼ 3.6%
-29.19M▲ 14.1%
-29.1M▲ 0.3%
-47.94M▼ 64.8%
-42.82M▲ 10.7%
-45.68M▲ 0%
Pretax Margin %
----------
Income Tax
-26K-124K-18K-18K-21K-36K-32K-30K-64K-72K
Effective Tax Rate %
0.2%0.6%0.07%0.05%0.06%0.12%0.11%0.06%0.15%0.16%
Net Income
-12.86M▲ 0%
-20.55M▼ 59.8%
-26.05M▼ 26.8%
-32.76M▼ 25.8%
-33.94M▼ 3.6%
-29.15M▲ 14.1%
-29.07M▲ 0.3%
-47.91M▼ 64.8%
-42.76M▲ 10.8%
-45.61M▲ 0%
Net Margin %
----------
Net Income Growth %
-15.99%-59.76%-26.79%-25.75%-3.61%14.11%0.3%-64.84%10.75%3.67%
Net Income (Continuing)
-12.86M-20.55M-26.05M-32.76M-33.94M-29.15M-29.07M-47.91M-42.76M-45.61M
Discontinued Operations
0000000000
Minority Interest
0000000000
EPS (Diluted)
-1.43▲ 0%
-2.29▼ 60.1%
-1.46▲ 36.2%
-1.81▼ 24.0%
-1.49▲ 17.7%
-0.45▲ 69.8%
-0.29▲ 35.6%
-0.47▼ 62.1%
-0.29▲ 38.3%
-0.31▲ 0%
EPS Growth %
-107.25%-60.14%36.24%-23.97%17.68%69.8%35.56%-62.07%38.3%28.06%
EPS (Basic)
-1.43-2.29-1.46-1.81-1.49-0.45-0.29-0.47-0.29-
Diluted Shares Outstanding
8.97M8.97M17.83M18.06M22.84M64.54M99.03M101.04M145.1M145.59M
Basic Shares Outstanding
8.97M8.97M17.83M18.06M22.84M64.54M99.03M101.04M145.1M145.59M
Dividend Payout Ratio
----------

TRVI Balance Sheet

Trevi Therapeutics, Inc. (TRVI) balance sheet — assets, liabilities & shareholders' equity

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
22.16M18.79M59.55M46.27M37.96M122.62M87.55M109.43M191.66M176.12M
Cash & Short-Term Investments
22.02M17.16M57.31M45M36.83M120.51M82.97M107.62M188.26M171.78M
Cash Only
22.02M17.16M57.31M45M36.83M12.59M32.4M34.1M18.91M19.41M
Short-Term Investments
00000107.92M50.57M73.53M169.35M152.37M
Accounts Receivable
0184K558K0241K00532K986K0
Days Sales Outstanding
----------
Inventory
63K1.4M00000000
Days Inventory Outstanding
-22.15K--------
Other Current Assets
49K077K265K01.31M955K335K2.41M4.34M
Total Non-Current Assets
66K1.7M449K862K518K399K1.86M1.47M1.78M3.48M
Property, Plant & Equipment
14K149K430K330K184K194K1.56M1.23M855K875K
Fixed Asset Turnover
---------0.00x
Goodwill
0000000000
Intangible Assets
0000000000
Long-Term Investments
0000000000
Other Non-Current Assets
52K1.55M19K532K334K205K297K243K928K2.61M
Total Assets
22.23M▲ 0%
20.49M▼ 7.8%
60M▲ 192.8%
47.13M▼ 21.4%
38.48M▼ 18.4%
123.02M▲ 219.7%
89.4M▼ 27.3%
110.9M▲ 24.0%
193.44M▲ 74.4%
179.61M▲ 0%
Asset Turnover
---------0.00x
Asset Growth %
164.34%-7.82%192.84%-21.45%-18.37%219.73%-27.32%24.05%74.43%513.85%
Total Current Liabilities
7.13M2.68M5.2M5.55M12.72M13.4M5.82M10.51M9.75M7.12M
Accounts Payable
537K603K1.6M2.02M2.85M2.86M1.81M3.41M3.91M2.21M
Days Payables Outstanding
-9.57K14.96K15.66K-----31.69K
Short-Term Debt
5.29M0005.83M7M00307K318K
Deferred Revenue (Current)
0000000000
Other Current Liabilities
00776K0114K01.61M2.54M5.53M4.58M
Current Ratio
3.11x7.02x11.45x8.33x2.98x9.15x15.03x10.41x19.66x24.75x
Quick Ratio
3.10x6.50x11.45x8.33x2.98x9.15x15.03x10.41x19.66x24.75x
Cash Conversion Cycle
----------
Total Non-Current Liabilities
325K506K257K14.29M8.68M2.16M1.03M747K446K364K
Long-Term Debt
01.1M013.95M8.65M2.15M000364K
Capital Lease Obligations
046K257K144K24K2K1.03M747K446K1.58M
Deferred Tax Liabilities
0000000000
Other Non-Current Liabilities
325K460K0196K03K0000
Total Liabilities
7.45M3.18M5.46M19.85M21.4M15.56M6.86M11.26M10.2M7.48M
Total Debt
5.29M1.1M356K14.21M14.63M9.18M1.34M1.03M753K682K
Net Debt
-16.73M-16.07M-56.96M-30.79M-22.2M-3.41M-31.06M-33.06M-18.16M-18.73M
Debt / Equity
0.36x0.06x0.01x0.52x0.86x0.09x0.02x0.01x0.00x0.00x
Debt / EBITDA
----------0.01x
Net Debt / EBITDA
---------0.36x
Interest Coverage
-2.46x-117.79x--70.88x-27.25x-35.93x-73.42x-11984.25x--
Total Equity
14.78M▲ 0%
17.31M▲ 17.1%
54.55M▲ 215.2%
27.28M▼ 50.0%
17.07M▼ 37.4%
107.46M▲ 529.3%
82.55M▼ 23.2%
99.64M▲ 20.7%
183.24M▲ 83.9%
172.13M▲ 0%
Equity Growth %
184.88%17.11%215.16%-49.98%-37.41%529.34%-23.18%20.71%83.9%578.77%
Book Value per Share
1.651.933.061.510.751.660.830.991.261.18
Total Shareholders' Equity
14.78M17.31M54.55M27.28M17.07M107.46M82.55M99.64M183.24M172.13M
Common Stock
4K101K18K19K29K60K68K94K128K128K
Retained Earnings
-84.43M-109.5M-114.22M-146.98M-180.92M-210.07M-239.13M-287.05M-329.8M-343M
Treasury Stock
0000000000
Accumulated OCI
-23K-46K000-122K-29K61K148K-190K
Minority Interest
0000000000

TRVI Cash Flow Statement

Trevi Therapeutics, Inc. (TRVI) cash flow — operating, investing & free cash flow history

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
-7.97M-18.29M-23.09M-29M-28.95M-28.18M-31.71M-38.26M-42.09M-45.3M
Operating CF Margin %
----------
Operating CF Growth %
28.74%-129.35%-26.25%-25.58%0.19%2.66%-12.55%-20.64%-10.02%-33.92%
Net Income
-12.86M-20.55M-26.05M-32.76M-33.94M-29.15M-29.07M-47.91M-42.76M-45.61M
Depreciation & Amortization
4K23K39K47K50K43K123K147K144K141K
Stock-Based Compensation
205K496K1.13M2.42M2.54M2.33M2.25M3.59M5.18M6.17M
Deferred Taxes
1.35M000-82K00000
Other Non-Cash Items
2.6M2.3M215K236K974K-162K-1.17M-907K-1.17M-1.21M
Working Capital Changes
722K-568K1.58M1.06M1.51M-1.23M-3.85M6.83M-3.49M-4.79M
Change in Receivables
-30-135K-374K293K000000
Change in Inventory
0000000000
Change in Payables
92K66K777K417K831K9K-1.05M1.6M-598K-88K
Cash from Investing
-13K-158K-9K-32K0-107.37M59.43M-21.53M-94.11M-67.19M
Capital Expenditures
-13K-158K-9K-32K0-159K-137K-35K-12K-114K
CapEx % of Revenue
----------
Acquisitions
00000-829K0000
Investments
----------
Other Investing
00000829K01.37M1.64M981K
Cash from Financing
21.72M3.63K73.21M16.72M20.77M111.31M-7.91M61.48M121.01M112.53M
Debt Issued (Net)
-8.25M-4.81M014M-68K-5.83M-9.41M-126K00
Equity Issued (Net)
29.92M8.96M75.06M3.13M21.18M105.41M1.71M61.15M120.3M110.18M
Dividends Paid
0000000000
Share Repurchases
0-1.53M00000000
Other Financing
52K-520K-1.85M-415K-340K11.73M-211K464K714K2.35M
Net Change in Cash
13.73M▲ 0%
-14.82M▼ 207.9%
50.11M▲ 438.2%
-12.31M▼ 124.6%
-8.17M▲ 33.6%
-24.24M▼ 196.7%
19.81M▲ 181.7%
1.7M▼ 91.4%
-15.18M▼ 993.1%
38K▲ 0%
Free Cash Flow
-7.99M▲ 0%
-18.45M▼ 131.0%
-23.1M▼ 25.2%
-29.03M▼ 25.7%
-28.95M▲ 0.3%
-28.33M▲ 2.1%
-31.85M▼ 12.4%
-38.29M▼ 20.2%
-42.1M▼ 10.0%
-31.94M▲ 0%
FCF Margin %
----------
FCF Growth %
28.63%-130.96%-25.22%-25.67%0.3%2.11%-12.4%-20.23%-9.95%22.67%
FCF per Share
-0.89-2.06-1.30-1.61-1.27-0.44-0.32-0.38-0.29-0.22
FCF Conversion (FCF/Net Income)
0.62x0.89x0.89x0.89x0.85x0.97x1.09x0.80x0.98x0.70x
Interest Paid
000180K000000
Taxes Paid
0000000000

TRVI Key Ratios

Trevi Therapeutics, Inc. (TRVI) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201720182019202020212022202320242025TTM
Return on Equity (ROE)
-87.02%-128.07%-72.51%-80.07%-153.03%-46.82%-30.59%-52.59%-30.23%-24.53%
Return on Invested Capital (ROIC)
--1115.19%----45.35%-32.72%-65.46%-31.94%-29.62%
Debt / Equity
0.36x0.06x0.01x0.52x0.86x0.09x0.02x0.01x0.00x0.00x
Interest Coverage
-2.46x-117.79x--70.88x-27.25x-35.93x-73.42x-11984.25x--
FCF Conversion
0.62x0.89x0.89x0.89x0.85x0.97x1.09x0.80x0.98x0.70x
Related:TRVI Dividend History·TRVI Revenue History·TRVI Price History·TRVI P/E History·TRVI Financial Ratios·TRVI Institutional Holders

TRVI SEC Filings & Documents

Trevi Therapeutics, Inc. (TRVI) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 5, 2026·SEC

Material company update

Apr 17, 2026·SEC

Material company update

Mar 17, 2026·SEC

10-K Annual Reports

4
FY 2026

Mar 17, 2026·SEC

FY 2025

Mar 18, 2025·SEC

FY 2024

Mar 20, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 5, 2026·SEC

FY 2025

Nov 13, 2025·SEC

FY 2025

Aug 7, 2025·SEC

TRVI Frequently Asked Questions

Trevi Therapeutics, Inc. (TRVI) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Trevi Therapeutics, Inc. (TRVI) grew revenue by 0.0% over the past year. Growth has been modest.

Trevi Therapeutics, Inc. (TRVI) reported a net loss of $45.6M for fiscal year 2025.

Dividend & Returns

Trevi Therapeutics, Inc. (TRVI) has a return on equity (ROE) of -30.2%. Negative ROE indicates the company is unprofitable.

Trevi Therapeutics, Inc. (TRVI) had negative free cash flow of $31.9M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in TRVI back in 2016?

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