Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in TRVI held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | NEA Management Company, LLC | 13.2M | $157.7M | 0.0% | 9.313% | 8.97% |
| 2 | BlackRock, Inc. | 10.2M | $122.2M | +1.1% | 7.212% | 0.00% |
| 3 | Frazier Life Sciences Management, L.P. | 9.9M | $118.6M | -3.1% | 7.001% | 3.05% |
| 4 | FMR LLC | 8.0M | $95.9M | +23.7% | 5.661% | 0.01% |
| 5 | WELLINGTON MANAGEMENT GROUP LLP | 5.2M | $61.9M | +52.4% | 3.655% | 0.01% |
| 6 | Vivo Capital, LLC | 5.1M | $60.8M | 0.0% | 3.588% | 5.07% |
| 7 | VANGUARD CAPITAL MANAGEMENT LLC | 5.0M | $59.4M | β | 3.506% | 0.00% |
| 8 | MARSHALL WACE, LLP | 4.0M | $47.3M | -13.4% | 2.793% | 0.05% |
| 9 | Rubric Capital Management LP | 3.7M | $44.3M | -1.4% | 2.615% | 0.54% |
| 10 | MPM Oncology Impact Management LP | 3.3M | $39.4M | +0.4% | 2.323% | 3.04% |
| 11 | VIKING GLOBAL INVESTORS LP | 3.2M | $38.2M | 0.0% | 2.253% | 0.11% |
| 12 | ALLIANCEBERNSTEIN L.P. | 2.8M | $35.6M | -7.7% | 2.004% | 0.01% |
| 13 | GEODE CAPITAL MANAGEMENT, LLC | 2.8M | $33.2M | +15.1% | 1.957% | 0.00% |
| 14 | STATE STREET CORP | 2.7M | $31.8M | +9.5% | 1.877% | 0.00% |
| 15 | EVENTIDE ASSET MANAGEMENT, LLC | 2.6M | $31.3M | 0.0% | 1.847% | 0.52% |
| 16 | ORBIMED ADVISORS LLC | 2.5M | $29.3M | -23.1% | 1.729% | 0.62% |
| 17 | Logos Global Management LP | 2.4M | $28.6M | +54.8% | 1.690% | 1.43% |
| 18 | Vestal Point Capital, LP | 2.2M | $25.8M | β | 1.526% | 0.72% |
| 19 | ACORN CAPITAL ADVISORS, LLC | 2.1M | $25.6M | 0.0% | 1.511% | 7.27% |
| 20 | Artia Global Partners LP | 2.0M | $24.0M | 0.0% | 1.418% | 4.91% |
| 21 | Affinity Asset Advisors, LLC | 2.0M | $23.9M | -7.0% | 1.409% | 1.39% |
| 22 | FRONTIER CAPITAL MANAGEMENT CO LLC | 2.0M | $23.8M | +79.9% | 1.405% | 0.24% |
| 23 | EMERALD ADVISERS, LLC | 1.8M | $21.9M | -2.8% | 1.296% | 0.69% |
| 24 | Siren, L.L.C. | 1.8M | $21.3M | -21.9% | 1.259% | 0.59% |
| 25 | RAYMOND JAMES FINANCIAL INC | 1.8M | $20.9M | -6.7% | 1.259% | 0.01% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in TRVI β a direct measure of their conviction.
Filings activity in TRVI during Q1 2026, grouped by how each filer changed its position.
Institutions that opened a new TRVI position in Q1 2026
Institutions that fully closed their TRVI position in Q1 2026
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 197 | +8.2% | 80.28% | 0.74 pp | $1.62B | 0.9% |
| Q4 2025 | 182 | +12% | 81.02% | +21.77 pp | $1.63B | +37% |
| Q3 2025 | 162 | +5.9% | 59.25% | +28.55 pp | $1.20B | +93% |
| Q2 2025 | 153 | +11% | 30.70% | +3.79 pp | $619M | +14% |
| Q1 2025 | 138 | +28% | 26.91% | +10.85 pp | $543M | +68% |
| Q4 2024 | 108 | +17% | 16.06% | +6.70 pp | $324M | +72% |
| Q3 2024 | 92 | +19% | 9.36% | +1.31 pp | $189M | +16% |
| Q2 2024 | 77 | β | 8.05% | β | $162M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying TRVI stock.
Based on Q1 2026 13F filings, institutional ownership of Trevi Therapeutics, Inc. stands at 80.3%, held across 197 reporting institutions.
NEA Management Company, LLC is the largest reported institutional holder of TRVI, with approximately 13,222,228 shares worth $0.16B as of Q1 2026.
Yes β 1 widely-followed marquee investor appear among the top 25 institutional holders of TRVI, including VIKING GLOBAL INVESTORS LP.
Our composite Smart Money Score for TRVI is 47 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
42 institutions opened new positions in TRVI during Q1 2026, while 27 fully exited. 52 added to existing positions and 102 trimmed.
TRVI institutional ownership fell by 0.74 percentage points quarter-over-quarter, with a net change of +15 holders.
The top 10 institutions account for 49.9% of all reported 13F value in TRVI, and the top 25 account for 75.5%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.