Cash declined 71% from $254.4M in 2024Q1 to $73.8M in 2026Q2, with a current ratio of 14.91 but only ~1.6 quarters of cash runway, while debt remains minimal at $5.6M (D/E 0.02).
Tyra Biosciences, Inc. (TYRA) balance sheet — 7-year assets, liabilities & shareholders' equity history
| Metric | TTM | Dec'25 | Dec'24 | Dec'23 | Dec'22 | Dec'21 | Dec'20 | Dec'19 |
|---|
| Total Current Assets | 366.97M | 265.45M | 347.46M | 211.67M | 257.29M | 304.06M | 15.28M | 127K |
| Cash & Short-Term Investments | 353.94M | 256M | 341.44M | 203.47M | 251.21M | 302.18M | 15.22M | 108K |
| Cash Only | 73.83M | 77.39M | 91.97M | 58.01M | 251.21M | 302.18M | 15.22M | 108K |
| Short-Term Investments | 280.11M | 178.62M | 249.47M | 145.46M | 0 | 0 | 0 | 0 |
| Accounts Receivable | 0 | 0 | 2M | 0 | 0 | 0 | 0 | 0 |
| Days Sales Outstanding | - | - | - | - | - | - | - | - |
| Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Days Inventory Outstanding | - | - | - | - | - | - | - | - |
| Other Current Assets | 13.02M | 9.45M | 4.02M | 8.2M | 6.08M | 0 | 0 | 0 |
| Total Non-Current Assets | 15.51M | 17.16M | 16.09M | 14.19M | 8.89M | 2.64M | 730K | 401K |
| Property, Plant & Equipment | 6.48M | 6.89M | 7.72M | 8.15M | 3.54M | 2.09M | 466K | 276K |
| Fixed Asset Turnover | 0.00x | - | - | - | - | - | - | - |
| Goodwill | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Intangible Assets | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Long-Term Investments | 1M | 0 | 0 | 0 | 0 | 0 | 243K | 0 |
| Other Non-Current Assets | 9.03M | 10.27M | 8.38M | 6.03M | 5.35M | 555K | 21K | 125K |
| Total Assets | 383.36M | 282.61M | 363.56M | 225.86M | 266.18M | 306.7M | 16.01M | 528K |
| Asset Turnover | 0.00x | - | - | - | - | - | - | - |
| Asset Growth % | -3.75% | -22.27% | 60.97% | -15.15% | -13.21% | 1815.56% | 2932.39% | - |
| Total Current Liabilities | 24.62M | 18.09M | 14.59M | 15.33M | 5.7M | 3.62M | 1.86M | 5.16M |
| Accounts Payable | 2.33M | 1.18M | 590K | 4.66M | 1.15M | 599K | 664K | 327K |
| Days Payables Outstanding | 6.05K | - | - | - | - | - | 5.16K | 14.92K |
| Short-Term Debt | 0 | 472K | 412K | 0 | 0 | 0 | 0 | 0 |
| Deferred Revenue (Current) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Current Liabilities | 0 | 10.91M | 7.14M | 5.27M | 0 | 0 | 278K | 4.33M |
| Current Ratio | 14.91x | 14.67x | 23.81x | 13.80x | 45.13x | 84.09x | 8.22x | 0.02x |
| Quick Ratio | 14.91x | 14.67x | 23.81x | 13.80x | 45.13x | 84.09x | 8.22x | 0.02x |
| Cash Conversion Cycle | - | - | - | - | - | - | - | - |
| Total Non-Current Liabilities | 5.08M | 5.34M | 5.81M | 6.26M | 2.65M | 1.35M | 27.79M | 114K |
| Long-Term Debt | 0 | 5.34M | 0 | 0 | 0 | 0 | 0 | 0 |
| Capital Lease Obligations | 10.54M | 0 | 5.81M | 6.22M | 2.48M | 981K | 0 | 114K |
| Deferred Tax Liabilities | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Current Liabilities | 0 | 0 | 3K | 46K | 169K | 367K | 27.79M | 0 |
| Total Liabilities | 29.7M | 23.43M | 20.41M | 21.59M | 8.35M | 4.96M | 29.65M | 5.27M |
| Total Debt | 5.58M | 5.81M | 6.22M | 6.5M | 2.62M | 1.18M | 142K | 253K |
| Net Debt | -68.25M | -71.58M | -85.74M | -51.51M | -248.59M | -301M | -15.08M | 145K |
| Debt / Equity | 0.02x | 0.02x | 0.02x | 0.03x | 0.01x | 0.00x | - | - |
| Debt / EBITDA | -0.03x | - | - | - | - | - | - | - |
| Net Debt / EBITDA | 0.43x | - | - | - | - | - | - | - |
| Interest Coverage | - | - | - | - | - | - | -9335.00x | -3122.00x |
| Total Equity | 353.66M | 259.18M | 343.15M | 204.26M | 257.83M | 301.74M | -13.64M | -4.74M |
| Equity Growth % | -10.2% | -24.47% | 68% | -20.78% | -14.55% | 2312.47% | -187.66% | - |
| Book Value per Share | 5.36 | 4.35 | 6.00 | 4.78 | 6.16 | 7.28 | -0.32 | -0.11 |
| Total Shareholders' Equity | 353.66M | 259.18M | 343.15M | 204.26M | 257.83M | 301.74M | -13.64M | -4.74M |
| Common Stock | 6K | 5K | 5K | 4K | 4K | 4K | 0 | 0 |
| Retained Earnings | -456.12M | -371.26M | -251.31M | -164.83M | -95.7M | -40.37M | -14.08M | -4.74M |
| Treasury Stock | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Accumulated OCI | -580K | 393K | 770K | 381K | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quick answers to the most common questions about buying TYRA stock.
As of 2025, Tyra Biosciences, Inc. (TYRA) had total assets of $282.6M including $265.4M in current assets.
Tyra Biosciences, Inc. (TYRA) carries total debt of $5.8M, offset by $256.0M in cash and short-term investments. Comparing total debt to cash helps evaluate the company's debt burden and net leverage.
Tyra Biosciences, Inc. (TYRA) has total shareholders' equity (book value) of $259.2M ($4.35 book value per share). Book value represents the net worth of the company belonging to common stock holders.
Tyra Biosciences, Inc. (TYRA) reported a current ratio of 14.67x. A current ratio above 1.0x indicates that the company has more current assets than current liabilities, suggesting sufficient short-term liquidity.
Key Metrics
Top Statement Risk
Accelerating cash burn
Metrics are mathematically derived from official filings.
Cash Buffer Eroding as Losses Mount
TYRA's cash fell from $254.4M in 2024Q1 to $73.8M in 2026Q2, a 71% decline, while quarterly net losses widened to $45.6M, indicating a shrinking runway despite a still-positive equity base.
The balance sheet is weakening as cash reserves deplete faster than the equity cushion can absorb, with total assets dropping from $404.7M to $383.4M over the period. The equity base remains positive but is being eroded by cumulative losses, suggesting that without new capital, the company's financial flexibility will diminish. This trajectory implies that the company is in a race to reach value-inflecting milestones before funding needs become acute.
Liquidity Ratios Mask Shrinking Runway
Current ratio remains high at 14.91 in 2026Q2, but cash of $73.8M covers only about 1.6 quarters of operating burn, based on recent cash outflows, signaling a tightening liquidity position.
The current ratio is misleading because it includes non-cash current assets, while the company's operating cash burn averaged around $23M per quarter over the last year. With cash at $73.8M and no revenue, the company has limited buffer against shocks, and the high current ratio does not offset the rapid depletion of cash. Investors should monitor the cash runway closely, as the company may need to raise capital within the next few quarters.
Equity Quality Eroded by Persistent Losses
Retained earnings deteriorated from -$183.0M in 2024Q1 to -$456.1M in 2026Q2, while equity fell from $389.9M to $353.7M, reflecting a cumulative loss of over $270M in two years.
The equity base is increasingly composed of paid-in capital rather than retained earnings, as accumulated deficits grow. The company has not engaged in significant share repurchases or dividends, so dilution from future capital raises is a key risk. The negative retained earnings trend suggests that the company's book value is being consumed by R&D investment, which may be justified if it leads to successful drug development, but it also highlights the need for external funding.
Asset-Light Model with Minimal Tangible Base
PP&E is only $6.5M in 2026Q2, representing less than 2% of total assets, and goodwill is zero, underscoring a research-driven model with negligible fixed assets.
The asset mix is dominated by cash and other current assets, with no goodwill or significant intangibles, indicating that the company's value lies in its pipeline rather than physical assets. The minimal PP&E suggests that TYRA outsources manufacturing and relies on partnerships, which reduces capital intensity but also means that the balance sheet provides little collateral for debt financing. This asset-light structure is typical of clinical-stage biotechs but implies that the company's viability depends on its ability to execute on R&D.
Minimal Debt but Rising Relative to Cash
Total debt is stable at $5.6M in 2026Q2, with a D/E ratio of 0.02, but debt now represents 7.6% of cash, up from 2.6% in 2024Q1, as cash declines.
The company carries negligible debt, which provides financial flexibility, but the fixed debt level becomes more burdensome as cash reserves shrink. The low leverage is a positive, but it also indicates that the company has not used debt to extend its runway, relying instead on equity financing. Given the cash burn, the company may need to tap debt markets or issue equity, which could dilute shareholders or increase leverage.
SBC Distorts True Cash Burn
Stock-based compensation rose from $4.1M in 2024Q1 to $10.2M in 2026Q2, per income statement, representing about 22% of operating losses, which may overstate the cash consumption implied by net losses.
While net losses are widening, a significant portion is non-cash SBC, which does not consume cash. However, the cash flow statement shows operating cash outflows averaging 0.75x net losses, indicating that the cash burn is still substantial. The growing SBC suggests that the company is using equity to compensate employees, which could lead to dilution if the stock price declines. Investors should adjust for SBC to assess the true cash runway, which appears shorter than the net loss trend suggests.