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TYRATyra Biosciences, Inc.
$25.57$1.5B
Overview & Tools
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TYRA logo

Tyra Biosciences, Inc.

TYRA
NASDAQ · Biotechnology
$25.57
At close - Sep 22, 4:00 PM EDT - USD
Market Cap$1.53B
P/E-12.7x
52W High$40.65
Volume656.86K
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q2

Accelerating R&D Burn Challenges Cash Runway

Tyra Biosciences is a clinical-stage biotech with no revenue, aggressively investing in R&D, which grew 63% from $17.1M in 2024Q1 to $39.2M in 2026Q2, driving net losses to $45.6M in 2026Q2. The company's cash position has eroded from $254.4M to $73.8M over th...

GrowthDecelerating
ProfitabilityNegative
ValuationReview
TechnicalsWeak
Explore valuation models
MARKET ACTION

TYRA price & volume

Price trend, volume and key moving averages

Launch Terminal
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Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

5/12 Beats

EPS beat 5 of last 12 quarters

02

Valuation risk

-126% Peers

P/E is 126% below peer median

03

Market leadership

RS 18 · Lag

Laggard (Underperforming 82% of market)

04

Weak Trend

Below 200DMA

Price < 200DMA

Next CatalystEstimated earnings · Nov 4

Market performance

Price History →

Trailing total returns as of 9/23/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
TYRA-4.55%
S&P 500 (^GSPC)+13.20%
1-Year Return
TYRA+98.37%
S&P 500 (^GSPC)+15.98%
3-Year Return
TYRA+79.56%
S&P 500 (^GSPC)+74.03%
5-Year Return
TYRA+38.89%
S&P 500 (^GSPC)+88.76%

Growth & profitability

Annual revenue & EPS trend
Revenue
-
Net income
-$120M-38.7% YoY
Free cash flow
-$95M-35.3% YoY
Operating margin
-
ROIC (TTM)-44.8%
Avg ROIC 5Y-
ROE (TTM)-39.8%
Piotroski Score1 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate5/12 (42%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Aug 4, 2026
-$0.69-6.2%
vs -$0.65
—
vs —
Q2 2026
May 13, 2026
-$0.64-6.7%
vs -$0.60
—
vs —
Q2 2026
Mar 2, 2026
-$0.57-5.6%
vs -$0.54
—
vs —
Q4 2025
Nov 5, 2025
-$0.50+0.0%
vs -$0.50
—
vs —
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

5 Stories
PRNewsWire·Sep 14, 2026
Tyra Announces Pricing of $400 Million Underwritten Offering of Common Stock and Pre-Funded Warrants

CARLSBAD, Calif., Sept. 14, 2026 /PRNewswire/ -- Tyra Biosciences, Inc. (Nasdaq: TYRA), a clinical-stage biotechnology company focused on developing next-generation precision medicines that target large opportunities in Fibroblast Growth Factor Receptor (FGFR) biology, today announced the pricing of an underwritten offering of 9,079,000 shares of its common stock at a price of $22.03 per share and, in lieu of shares of common stock to certain investors, pre-funded warrants to purchase 9,078,529 shares of common stock at a purchase price of $22.029 per share, which equals the offering price per share of the common stock less the $0.001 exercise price per share of each pre-funded warrant.

Seeking Alpha·Sep 10, 2026
Tyra Biosciences, Inc. (TYRA) Discusses Initial SURF302 Results on Oral Dabogratinib for Intermediate Risk NMIBC Transcript

Tyra Biosciences, Inc. (TYRA) Discusses Initial SURF302 Results on Oral Dabogratinib for Intermediate Risk NMIBC Transcript

PRNewsWire·Sep 8, 2026
Tyra Biosciences to Present at the Cantor Global Healthcare Conference

CARLSBAD, Calif., Sept. 8, 2026 /PRNewswire/ -- Tyra Biosciences, Inc. (Nasdaq: TYRA), a clinical-stage biotechnology company focused on developing next-generation precision medicines that target large opportunities in Fibroblast Growth Factor Receptor (FGFR) biology, today announced participation at the following investor conference: Cantor Global Healthcare Conference 2026 Format: Virtual fireside chat and one-on-one investor meetingsPresentation Date/Time: Wednesday, September 9, 2026 at 1:00 PM ETLocation: New York, NY A live webcast of the presentation can be accessed by visiting the "For Investors" page on the Tyra Biosciences  website  and will be available for replay following the event.

Seeking Alpha·Sep 6, 2026
Tyra Biosciences: 'Hold' IR-NMIBC Data September 9th 2026, With Caution Ahead For 2027 Readouts

Tyra Biosciences is downgraded to "Hold" ahead of key phase 2 SURF302 data for dabogratinib in FGFR3-altered IR-NMIBC patients. Multiple phase 2 readouts, including SURF302, SURF303, and BEACH301, create significant near-term binary risk and opportunity for the company. Company's SNAP platform enables selective FGFR3 targeting, aiming to address efficacy and tolerability gaps left by pan-FGFR inhibitors.

Filtered for Tyra Biosciences, Inc.More Headlines
04

Compare before deciding

Benchmark TYRA against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Tyra Biosciences, Inc. (TYRA)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
TYRA logoTYRATyra Biosciences, Inc.Current
$25.57$1.53B-12.72——-39.83%—
KROS logoKROSKeros Therapeutics, Inc.
$11.73$375.34M5.106774.96%-553.88%-21.4%—
NUVL logoNUVLNuvalent, Inc.
$123.96$9.13B-21.19——-42.78%—
PRAX logoPRAXPraxis Precision Medicines, Inc.
$300.65$8.38B-22.30-100%—-34.15%—
MRUS logoMRUSMerus N.V.
$90.00$6.83B-26.87-12.38%-654.43%-50.62%—
ERAS logoERASErasca, Inc.
$15.55$5.4B-35.34——-80.43%—

Compare TYRA vs Peers

Tyra Biosciences, Inc. (TYRA) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs KROS

Most directly comparable listed peer for TYRA.

Scale Benchmark

vs MEDP

Larger-name benchmark to compare TYRA against a more recognizable public peer.

Peer Set

Compare Top 5

vs KROS, NUVL, PRAX, MRUS

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

TYRA SEC Filings & Documents

Tyra Biosciences, Inc. (TYRA) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Aug 4, 2026·SEC

Material company update

Jun 2, 2026·SEC

Material company update

May 13, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 2, 2026·SEC

FY 2025

Mar 27, 2025·SEC

FY 2024

Mar 19, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Aug 4, 2026·SEC

FY 2026

May 13, 2026·SEC

FY 2025

Nov 5, 2025·SEC

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TYRA Frequently Asked Questions

Tyra Biosciences, Inc. (TYRA) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is TYRA profitable?

Tyra Biosciences, Inc. (TYRA) reported a net loss of $148.6M for fiscal year 2025.

Dividend & Returns
What is TYRA's return on equity?

Tyra Biosciences, Inc. (TYRA) has a return on equity (ROE) of -39.8%. Negative ROE indicates the company is unprofitable.

What is Tyra Biosciences, Inc.'s free cash flow?

Tyra Biosciences, Inc. (TYRA) had negative free cash flow of $109.9M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in TYRA back in 2019?

Total return calculator · dividends reinvested · 7+ years of data

See returns →