Last 48 quarters of trend data · Healthcare · Biotechnology
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | -5.11 | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/S Ratio | 20.32 | 3539.35 | 4998.26 | 6.25 | 3802.26 | 3807.36 | 5328.47 | 4392.61 | 2884.54 | 3714.74 | 3757.19 | 2325.21 | 3572.92 |
| — | -7.0% | -6.2% | -99.9% | +31.8% | +2.5% | +41.8% | +88.9% | -19.3% | +35.5% | +33.3% | +1506.0% | +1039.0% | |
| P/B Ratio | 1.99 | 3.14 | 3.65 | 3.51 | 2.21 | 1.81 | 2.28 | 2.14 | 1.57 | 1.84 | 2.45 | 2.36 | 3.26 |
| — | +73.0% | +59.9% | +64.3% | +41.1% | -1.2% | -6.7% | -9.6% | -51.8% | -40.1% | -18.3% | +39.6% | +43.9% | |
| P/FCF | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBIT | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
Viridian Therapeutics, Inc.'s operating margin was -82389.4% in Q1 2026, up 10602.3 pp QoQ and up 47980.1 pp YoY. The trailing four-quarter average of -79448.4% exceeds the current quarter, suggesting the latest result may reflect seasonal weakness or a one-off headwind. Gross margin contracted 85.8% YoY, suggesting cost inflation or competitive pricing pressure.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 100.0% | 14.2% | -142.4% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% |
| — | -85.8% | -242.4% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | +100.3% | +105.7% | +101.2% | |
| Operating Margin | -512.9% | -82389.4% | -92991.7% | -56.7% | -142356.0% | -130369.4% | -121488.9% | -97069.8% | -100259.7% | -77634.7% | -99275.0% | -71144.4% | -82326.4% |
| — | +36.8% | +23.5% | +99.9% | -42.0% | -67.9% | -22.4% | -36.4% | -21.8% | -5.0% | -112.4% | -2754.4% | -612.9% | |
| Net Margin | -483.6% | -74397.9% | -91178.0% | -49.0% | -134313.3% | -120711.1% | -110729.2% | -89173.3% | -90268.1% | -67419.4% | -92861.1% | -66194.4% | -76476.4% |
| — | +38.4% | +17.7% | +99.9% | -48.8% | -79.0% | -19.2% | -34.7% | -18.0% | +3.1% | -113.0% | -2636.6% | -563.9% |
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -49.2% | -15.4% | -19.6% | -6.8% | -18.0% | -13.6% | -11.6% | -12.4% | -11.7% | -9.5% | -18.4% | -15.9% | -16.5% |
| — | -13.4% | -69.9% | +45.2% | -53.9% | -43.7% | +37.3% | +22.0% | +29.3% | +48.2% | -61.8% | -51.5% | +13.6% | |
| ROA | -41.7% | -12.4% | -16.3% | -6.0% | -16.2% | -12.4% | -10.5% | -11.3% | -10.7% | -8.7% | -16.3% | -14.0% | -14.9% |
| — | -0.3% | -54.8% | +47.2% | -51.6% | -43.0% | +35.5% | +19.4% | +28.4% | +47.8% | -56.1% | -48.0% | +10.7% | |
| ROIC | -47.3% | -16.3% | -20.1% | -7.7% | -17.2% | -12.8% | -11.7% | -12.9% | -11.3% | -9.6% | -19.4% | -18.0% | -17.7% |
| — | -27.4% | -71.5% | +40.1% | -52.0% | -32.8% | +39.6% | +28.3% | +36.0% | +54.7% | +17.1% | +25.2% | -0.8% |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
The current ratio has weakened 22.3% YoY to 15.15x, tightening the short-term liquidity position. Debt/Equity has risen for 7 consecutive quarters, indicating increasing financial leverage that investors should watch closely.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.07 | 0.08 | 0.07 | 0.05 | 0.04 | 0.04 | 0.03 | 0.03 | 0.04 | 0.04 | 0.05 | 0.07 | 0.02 |
| — | +129.2% | +123.5% | +58.7% | +4.6% | -2.9% | -34.0% | -59.4% | +126.9% | +138.5% | +257.8% | +480.1% | -52.1% | |
| Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Current Ratio | 12.65 | 15.15 | 12.65 | 11.28 | 11.01 | 19.49 | 15.43 | 18.55 | 15.82 | 23.99 | 18.26 | 13.93 | 12.09 |
| — | -22.3% | -18.0% | -39.2% | -30.4% | -18.8% | -15.5% | +33.2% | +30.9% | +89.9% | +43.5% | -19.7% | +55.6% | |
| Quick Ratio | 12.65 | 15.15 | 12.65 | 11.28 | 11.01 | 19.49 | 15.43 | 18.55 | 15.82 | 23.99 | 18.26 | 13.93 | 12.09 |
| — | -22.3% | -18.0% | -39.2% | -30.4% | -18.8% | -15.5% | +33.2% | +30.9% | +85.5% | +41.3% | -19.7% | +55.6% | |
| Interest Coverage | -68.24 | -33.56 | -17.21 | -60.78 | -194.98 | -147.31 | -91.92 | -75.38 | -107.87 | -81.70 | -71.99 | -85.37 | -330.70 |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Includes 30+ ratios · 48 years · Updated daily
Price is only half the story. See total return with reinvested dividends.
Launch CalculatorDCF intrinsic value, peer multiples, and analyst estimates — see what the stock is really worth.
View ValuationCompare business quality, growth, and profitability against top sector peers.
Start ComparisonQuick answers to the most common questions about buying VRDN stock.
Viridian Therapeutics, Inc.'s current P/E is -5.1x. Quarterly P/E ratios can vary due to seasonal revenue patterns and one-time charges.
Viridian Therapeutics, Inc.'s current operating margin is -512.9%. Margins have been expanding over recent quarters. Quarterly margins are particularly useful for identifying trend inflections that annual data smooths over.
Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking Viridian Therapeutics, Inc.'s business trajectory between earnings reports.