Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in XRTX held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | TD Waterhouse Canada Inc. | 47 | $19 | — | 0.017% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in XRTX — a direct measure of their conviction.
Filings activity in XRTX during Q1 2026, grouped by how each filer changed its position.
No institutions trimmed their position this quarter.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 1 | 80% | 0.00% | 2.43 pp | $0M | 100% |
| Q4 2025 | 5 | 17% | 2.43% | 10.99 pp | $0M | 82% |
| Q3 2025 | 6 | 25% | 13.42% | +3.29 pp | $0M | +32% |
| Q2 2025 | 8 | +167% | 10.13% | +10.06 pp | $0M | +14682% |
| Q1 2025 | 3 | 57% | 0.07% | 53.46 pp | $0M | 100% |
| Q4 2024 | 7 | 13% | 53.53% | +46.75 pp | $0M | +690% |
| Q3 2024 | 8 | +33% | 6.78% | +1.96 pp | $0M | +41% |
| Q2 2024 | 6 | — | 4.82% | — | $0M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying XRTX stock.
Based on Q1 2026 13F filings, institutional ownership of XORTX Therapeutics Inc. stands at 0.0%, held across 1 reporting institutions.
TD Waterhouse Canada Inc. is the largest reported institutional holder of XRTX, with approximately 47 shares worth $0.00B as of Q1 2026.
No marquee "smart money" managers (Berkshire, Burry, ARK, Tiger Global, Pershing Square, Baupost, etc.) currently appear among the top 25 institutional holders of XRTX.
Our composite Smart Money Score for XRTX is 13 out of 100 (Heavy Distribution). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
1 institutions opened new positions in XRTX during Q1 2026, while 5 fully exited. 0 added to existing positions and 0 trimmed.
XRTX institutional ownership fell by 2.43 percentage points quarter-over-quarter, with a net change of -4 holders.
The top 10 institutions account for 100.0% of all reported 13F value in XRTX, and the top 25 account for 100.0%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
XORTX Therapeutics Inc. (XRTX) Institutional Ownership