Ranked by reported Q2 2026 13F market value
Share of total reported institutional value in ANVS held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | Empery Asset Management, LP | 2.4M | $4.5M | β | 5.645% | 5.17% |
| 2 | MARSHALL WACE, LLP | 1.8M | $3.4M | +55.1% | 4.331% | 0.00% |
| 3 | VANGUARD CAPITAL MANAGEMENT LLC | 1.6M | $3.1M | +88.8% | 3.872% | 0.00% |
| 4 | TUDOR INVESTMENT CORP ET AL | 1.4M | $2.5M | β | 3.190% | 0.00% |
| 5 | RENAISSANCE TECHNOLOGIES LLC | 1.0M | $1.9M | +188.3% | 2.356% | 0.00% |
| 6 | TWO SIGMA INVESTMENTS, LP | 580K | $1.1M | -7.7% | 1.362% | 0.00% |
| 7 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 562K | $1.0M | +4.0% | 1.322% | 0.00% |
| 8 | CITADEL ADVISORS LLC | 506K | $942K | +382.8% | 1.191% | 0.00% |
| 9 | Caption Management, LLC | 475K | $883K | β | 1.116% | 0.00% |
| 10 | GEODE CAPITAL MANAGEMENT, LLC | 284K | $528K | +14.7% | 0.667% | 0.00% |
| 11 | BlackRock, Inc. | 250K | $465K | +79.1% | 0.587% | 0.00% |
| 12 | VANGUARD FIDUCIARY TRUST CO | 178K | $330K | +34.4% | 0.417% | 0.00% |
| 13 | Quadrature Capital Ltd | 91K | $169K | β | 0.214% | 0.00% |
| 14 | STATE STREET CORP | 78K | $145K | 0.0% | 0.183% | 0.00% |
| 15 | NORTHERN TRUST CORP | 68K | $127K | -52.0% | 0.160% | 0.00% |
| 16 | FIRST NATIONAL TRUST CO | 60K | $112K | +50.0% | 0.141% | 0.00% |
| 17 | JANE STREET GROUP, LLC | 59K | $110K | -32.1% | 0.138% | 0.00% |
| 18 | Sherry Group, Inc. | 57K | $107K | 0.0% | 0.135% | 0.10% |
| 19 | Headlands Technologies LLC | 48K | $89K | β | 0.113% | 0.01% |
| 20 | Wescott Financial Advisory Group, LLC | 42K | $77K | 0.0% | 0.098% | 0.01% |
| 21 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 38K | $70K | 0.0% | 0.089% | 0.00% |
| 22 | WELLS FARGO & COMPANY/MN | 30K | $56K | +111.8% | 0.071% | 0.00% |
| 23 | Dakota Wealth Management | 29K | $54K | +11.5% | 0.068% | 0.00% |
| 24 | CWA Asset Management Group, LLC | 28K | $52K | +64.7% | 0.066% | 0.00% |
| 25 | MILLENNIUM MANAGEMENT LLC | 23K | $44K | β | 0.055% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in ANVS β a direct measure of their conviction.
Filings activity in ANVS during Q2 2026, grouped by how each filer changed its position.
Institutions that opened a new ANVS position in Q2 2026
Institutions that fully closed their ANVS position in Q2 2026
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q2 2026 | 63 | +8.6% | 28.38% | +16.05 pp | $22M | +95% |
| Q1 2026 | 58 | +5.5% | 12.33% | +0.26 pp | $11M | 31% |
| Q4 2025 | 55 | +38% | 12.07% | +4.55 pp | $17M | +271% |
| Q3 2025 | 40 | 4.8% | 7.52% | +1.01 pp | $4M | +13% |
| Q2 2025 | 42 | 6.7% | 6.51% | 1.02 pp | $4M | +25% |
| Q1 2025 | 45 | +13% | 7.53% | +3.14 pp | $3M | 66% |
| Q4 2024 | 40 | +14% | 4.39% | +1.09 pp | $9M | 17% |
| Q3 2024 | 35 | β | 3.30% | β | $11M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying ANVS stock.
Based on Q2 2026 13F filings, institutional ownership of Annovis Bio, Inc. stands at 28.4%, held across 63 reporting institutions.
Empery Asset Management, LP is the largest reported institutional holder of ANVS, with approximately 2,401,476 shares worth $0.00B as of Q2 2026.
Yes β 6 widely-followed marquee investors appear among the top 25 institutional holders of ANVS, including RENAISSANCE TECHNOLOGIES LLC, TWO SIGMA INVESTMENTS, LP, SUSQUEHANNA INTERNATIONAL GROUP, LLP, CITADEL ADVISORS LLC, JANE STREET GROUP, LLC.
Our composite Smart Money Score for ANVS is 80 out of 100 (Strong Smart Money). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
15 institutions opened new positions in ANVS during Q2 2026, while 10 fully exited. 13 added to existing positions and 33 trimmed.
ANVS institutional ownership rose by 16.05 percentage points quarter-over-quarter, with a net change of +5 holders.
The top 10 institutions account for 89.0% of all reported 13F value in ANVS, and the top 25 account for 98.0%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Annovis Bio, Inc. (ANVS) Institutional Ownership