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Lipella Pharmaceuticals Inc. (LIPO) Total Return Calculator with Dividends Reinvested

Lipella Pharmaceuticals Inc.

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The total return for Lipella Pharmaceuticals Inc. (LIPO) stock is -99.09% over the past 12 months. So far it's down 86.84% this year. The 5-year total return is -99.61%, meaning $10,000 invested in LIPO stock 5 years ago would be worth $39 today. Total return includes price appreciation plus reinvesting any dividends paid out.

If you invested $10,000 in LIPO 1 year ago, it would be worth $93 today — you'd have lost $9,907.

With Dividends Reinvested$93-99.07%

Price Only (No DRIP)$93-99.07%

Period2025-05-07 → 2026-05-06

Price

Total Return (DRIP)

S&P 500

If You Invested $10,000 in LIPO

1Y$91-$9,909 (-99.1%)-99.1% CAGR

3Y$15-$9,985 (-99.9%)-88.6% CAGR

5Y$39-$9,961 (-99.6%)-67.0% CAGR

10Y$39-$9,961 (-99.6%)-42.6% CAGR

15Y$39-$9,961 (-99.6%)-30.9% CAGR

20Y$39-$9,961 (-99.6%)-24.2% CAGR

30Y$39-$9,961 (-99.6%)-16.9% CAGR

Lipella Pharmaceuticals Inc. did not pay dividends during this period. Total return = price return.

Loading LIPO total return...

As of 2026-05-07

Returns at a Glance

Period	Total Return	CAGR	Price Only	Div. Contrib.	$10K →
YTD	-86.84%	—	-86.84%	—	$1,316
1Y	-99.09%	-99.09%	-99.09%	—	$91
3Y	-99.85%	-88.58%	-99.85%	—	$15
5Y	-99.61%	-67.00%	-99.61%	—	$39
10Y	-99.61%	-42.56%	-99.61%	—	$39
15Y	-99.61%	-30.90%	-99.61%	—	$39
20Y	-99.61%	-24.21%	-99.61%	—	$39
30Y	-99.61%	-16.87%	-99.61%	—	$39

Risk & Highlights

Best Year+335.48%2022

Worst Year-94.34%2025

Max Drawdown-99.36%2025-06-05 → 2026-04-16

Annual Returns

Year	Total Return	Price Return	Div.	S&P 500	vs S&P
2026YTD	-6.43%	-6.43%	—	+0.41%	-6.8pp
2025	-94.34%	-94.34%	—	+16.64%	-111.0pp
2024	-59.50%	-59.50%	—	+24.00%	-83.5pp
2023	-68.13%	-68.13%	—	+24.81%	-92.9pp
2022	+335.48%	+335.48%	—	-19.95%	+355.4pp

LIPO underperformed the S&P 500 by 130.41pp over the past year (-99.09% vs +31.32%).

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LIPO Peers' Total Return

Accurate peer set · 10 comparable names

Name	Mkt Cap	30D Rtn	YTD Total Rtn	1Y Total Rtn	Div Contrib	3Y Total Rtn	5Y Total Rtn	10Y Total Rtn
LIPOLipella Pharmaceuticals Inc.	$23,584	+1.8%	-86.8%	-99.1%	—	-99.9%	-99.6%	-99.6%
SIGASIGA Technologies, Inc.	$337M	-9.6%	-15.5%	+0.6%	+11.4pp	+21.7%	+1.0%	+722.2%
NUVLNuvalent, Inc.	$6.9B	+0.5%	+3.4%	+52.9%	—	+176.1%	+456.1%	+456.1%
INVAInnoviva, Inc.	$1.9B	-2.2%	+13.3%	+20.4%	—	+92.8%	+95.5%	+90.5%
PRAXPraxis Precision Medicines, Inc.	$7.6B	+9.0%	+18.0%	+860.9%	—	+2005.6%	-18.4%	-19.0%
ALDXAldeyra Therapeutics, Inc.	$105M	+14.5%	-62.7%	-17.1%	—	-83.7%	-85.6%	-71.9%
RCKTRocket Pharmaceuticals, Inc.	$418M	+11.6%	+11.6%	-38.8%	—	-81.9%	-91.1%	-90.7%
HALOHalozyme Therapeutics, Inc.	$7.8B	+5.2%	-5.6%	+11.7%	—	+119.1%	+39.1%	+598.4%
PHATPhathom Pharmaceuticals, Inc.	$1.0B	+12.6%	-19.4%	+427.9%	—	+2.7%	-62.3%	-48.5%
ABBVAbbVie Inc.	$362.6B	-0.8%	-9.1%	+13.1%	+3.6pp	+52.0%	+102.8%	+306.7%
PFEPfizer Inc.	$150.8B	-4.8%	+7.0%	+23.4%	+7.5pp	-18.4%	-11.3%	+30.7%

Compare:LIPO vs SIGA LIPO vs NUVL LIPO vs INVA LIPO vs SIGA vs NUVL

About LIPO Dividend Returns

Lipella Pharmaceuticals Inc. (LIPO) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends.

How We Calculate Total Return

Our total return calculator simulates dividend reinvestment (DRIP) by assuming each dividend payment is used to purchase additional shares at the closing price on the ex-dividend date. This methodology provides an accurate representation of how a dividend reinvestment plan would perform.

Frequently Asked Questions

Q1What is the total return of LIPO over the past year?

Lipella Pharmaceuticals Inc. (LIPO) delivered a return of -99.09% over the past year. Since LIPO does not currently pay dividends, the total return equals the price-only return.

Q2How much would $10,000 invested in LIPO be worth today?

A $10,000 investment in Lipella Pharmaceuticals Inc. one year ago would be worth $91 today, representing a loss of $9,909.

Q3Does LIPO pay dividends?

Lipella Pharmaceuticals Inc. (LIPO) does not currently pay dividends. Many growth-focused companies reinvest profits back into the business rather than distributing them as dividends. For LIPO, the total return equals the price-only return.

Q4Did LIPO beat the S&P 500?

No, Lipella Pharmaceuticals Inc. (LIPO) underperformed the S&P 500 by 130.41 percentage points over the past year. LIPO delivered a total return of -99.09%, compared to the S&P 500's 31.32%. This means a passive S&P 500 index fund outperformed LIPO by 130.41pp during this period.

Q5What is LIPO's worst drawdown?

Lipella Pharmaceuticals Inc. (LIPO) experienced a maximum drawdown of -99.36% over the past year, declining from its peak on 2025-06-05 to its trough on 2026-04-16. The stock has not yet fully recovered to its prior peak. Maximum drawdown measures the worst peak-to-trough decline and is an important risk metric for investors.

Q6What is LIPO's long-term total return over 10, 20, or 30 years?

Here are Lipella Pharmaceuticals Inc. (LIPO)'s long-term returns with dividends reinvested. Over 10 years, the total return is -99.6% (-42.6% CAGR) — $10,000 would have grown to $39. Over 20 years: -99.6% total return (-24.2% CAGR) — $10,000 → $39. Over 30 years: -99.6% total return (-16.9% CAGR) — $10,000 → $39. Long-term investors benefit from compounding: dividends buy additional shares, which generate their own dividends, creating an exponential growth effect.

Q7What was LIPO's best and worst year?

Lipella Pharmaceuticals Inc.'s best calendar year was 2022 with a total return of 335.5%. Its worst year was 2025 with a total return of -94.3%. This range shows the volatility investors should expect — the difference between the best and worst year is 429.8 percentage points.