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Rhythm Pharmaceuticals, Inc. (RYTM) Total Return Calculator with Dividends Reinvested

Rhythm Pharmaceuticals, Inc.

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The total return for Rhythm Pharmaceuticals, Inc. (RYTM) stock is +43.32% over the past 12 months. So far it's down 12.09% this year. The 5-year total return is +333.79%, meaning $10,000 invested in RYTM stock 5 years ago would be worth $43,379 today. Total return includes price appreciation plus reinvesting any dividends paid out.

If you invested $10,000 in RYTM 1 year ago, it would be worth $15,406 today — you'd have gained $5,406.

With Dividends Reinvested$15,406+54.06%

Price Only (No DRIP)$15,406+54.06%

Period2025-05-06 → 2026-05-06

Price

Total Return (DRIP)

S&P 500

If You Invested $10,000 in RYTM

1Y$14,332+$4,332 (+43.3%)43.3% CAGR

3Y$55,309+$45,309 (+453.1%)76.8% CAGR

5Y$43,379+$33,379 (+333.8%)34.1% CAGR

10Y$30,770+$20,770 (+207.7%)11.9% CAGR

15Y$30,770+$20,770 (+207.7%)7.8% CAGR

20Y$30,770+$20,770 (+207.7%)5.8% CAGR

30Y$30,770+$20,770 (+207.7%)3.8% CAGR

Rhythm Pharmaceuticals, Inc. did not pay dividends during this period. Total return = price return.

Loading RYTM total return...

As of 2026-05-06

Returns at a Glance

Period	Total Return	CAGR	Price Only	Div. Contrib.	$10K →
YTD	-12.09%	—	-12.09%	—	$8,791
1Y	+43.32%	43.32%	+43.32%	—	$14,332
3Y	+453.09%	76.85%	+453.09%	—	$55,309
5Y	+333.79%	34.11%	+333.79%	—	$43,379
10Y	+207.70%	11.90%	+207.70%	—	$30,770
15Y	+207.70%	7.78%	+207.70%	—	$30,770
20Y	+207.70%	5.78%	+207.70%	—	$30,770
30Y	+207.70%	3.82%	+207.70%	—	$30,770

Risk & Highlights

Best Year+172.91%2022

Worst Year-67.13%2021

Max Drawdown-35.54%2025-12-11 → 2026-03-27

Annual Returns

Year	Total Return	Price Return	Div.	S&P 500	vs S&P
2026YTD	-11.69%	-11.69%	—	+0.41%	-12.1pp
2025	+78.19%	+78.19%	—	+16.64%	+61.6pp
2024	+24.04%	+24.04%	—	+24.00%	+0.0pp
2023	+60.51%	+60.51%	—	+24.81%	+35.7pp
2022	+172.91%	+172.91%	—	-19.95%	+192.9pp

RYTM outperformed the S&P 500 by 14.88pp over the past year (+43.32% vs +28.44%).

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RYTM Peers' Total Return

Accurate peer set · 10 comparable names

Name	Mkt Cap	30D Rtn	YTD Total Rtn	1Y Total Rtn	Div Contrib	3Y Total Rtn	5Y Total Rtn	10Y Total Rtn
RYTMRhythm Pharmaceuticals, Inc.	$6.3B	+6.2%	-12.1%	+43.3%	—	+453.1%	+333.8%	+207.7%
HALOHalozyme Therapeutics, Inc.	$7.8B	+4.4%	-6.3%	+8.7%	—	+112.5%	+37.8%	+584.0%
RAREUltragenyx Pharmaceutical Inc.	$2.5B	+9.4%	+6.0%	-35.7%	—	-47.0%	-76.4%	-60.0%
FOLDAmicus Therapeutics, Inc.	$4.5B	+0.3%	+1.5%	+121.9%	—	+19.3%	+51.1%	+121.9%
ACMRACM Research, Inc.	$3.5B	+26.7%	+17.6%	+167.9%	—	+404.3%	+112.0%	+2723.5%
PTCTPTC Therapeutics, Inc.	$5.4B	-5.6%	-15.2%	+60.0%	—	+16.5%	+59.1%	+845.3%
KRYSKrystal Biotech, Inc.	$8.4B	+8.7%	+15.3%	+75.3%	—	+237.8%	+296.0%	+2574.5%
VNDAVanda Pharmaceuticals Inc.	$437M	+6.0%	-10.4%	+61.0%	—	+6.3%	-55.4%	-15.4%
MDGLMadrigal Pharmaceuticals, Inc.	$11.4B	-5.9%	-15.4%	+64.0%	—	+64.0%	+287.8%	+3581.1%
NKTRNektar Therapeutics	$1.7B	+12.6%	+93.8%	+716.3%	—	+584.2%	-70.0%	-58.9%
VKTXViking Therapeutics, Inc.	$3.6B	-7.7%	-11.6%	+6.2%	—	+37.0%	+427.1%	+2404.8%

Compare:RYTM vs HALO RYTM vs RARE RYTM vs FOLD RYTM vs HALO vs RARE

About RYTM Dividend Returns

Rhythm Pharmaceuticals, Inc. (RYTM) is a dividend-paying stock. When dividends are reinvested through a DRIP (Dividend Reinvestment Plan), they purchase additional shares, which then generate their own dividends—creating a compounding effect that can significantly boost long-term returns.

How We Calculate Total Return

Our total return calculator simulates dividend reinvestment (DRIP) by assuming each dividend payment is used to purchase additional shares at the closing price on the ex-dividend date. This methodology provides an accurate representation of how a dividend reinvestment plan would perform.

Frequently Asked Questions

Q1What is the total return of RYTM over the past year?

Rhythm Pharmaceuticals, Inc. (RYTM) delivered a total return of 43.32% over the past year when dividends are reinvested. The price-only return was 43.32%, meaning dividends contributed an additional 0.00 percentage points to total returns.

Q2How much would $10,000 invested in RYTM be worth today?

A $10,000 investment in Rhythm Pharmaceuticals, Inc. one year ago would be worth $14,332 today with dividends reinvested (DRIP). Without reinvesting dividends, the same investment would be worth $14,332. Dividend reinvestment added $0 to the portfolio value.

Q3Does RYTM pay dividends?

Yes, Rhythm Pharmaceuticals, Inc. (RYTM) pays dividends. In the last year, RYTM paid approximately $0.08 per share in dividends (0.09% yield). Reinvesting these dividends through a DRIP can significantly boost long-term returns — over 20+ years, dividend compounding can account for 30–50% of total returns for dividend-paying stocks.

Q4Did RYTM beat the S&P 500?

Yes, Rhythm Pharmaceuticals, Inc. (RYTM) outperformed the S&P 500 by 14.88 percentage points over the past year. RYTM delivered a total return of 43.32%, compared to the S&P 500's 28.44%. This 14.88pp alpha means investors in RYTM earned more than a passive S&P 500 index fund.

Q5What is RYTM's worst drawdown?

Rhythm Pharmaceuticals, Inc. (RYTM) experienced a maximum drawdown of -35.54% over the past year, declining from its peak on 2025-12-11 to its trough on 2026-03-27. The stock has not yet fully recovered to its prior peak. Maximum drawdown measures the worst peak-to-trough decline and is an important risk metric for investors.

Q6What is RYTM's long-term total return over 10, 20, or 30 years?

Here are Rhythm Pharmaceuticals, Inc. (RYTM)'s long-term returns with dividends reinvested. Over 10 years, the total return is 207.7% (11.9% CAGR) — $10,000 would have grown to $30,770. Over 20 years: 207.7% total return (5.8% CAGR) — $10,000 → $30,770. Over 30 years: 207.7% total return (3.8% CAGR) — $10,000 → $30,770. Long-term investors benefit from compounding: dividends buy additional shares, which generate their own dividends, creating an exponential growth effect.

Q7What was RYTM's best and worst year?

Rhythm Pharmaceuticals, Inc.'s best calendar year was 2022 with a total return of 172.9%. Its worst year was 2021 with a total return of -67.1%. This range shows the volatility investors should expect — the difference between the best and worst year is 240.0 percentage points.