AstraZeneca PLC (AZN) — Estimates & Forecasts
Proprietary EPS, revenue & margin forecasts — FY+1 to FY+4
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Proprietary EPS, revenue & margin forecasts — FY+1 to FY+4
| Metric | 2023 | 2024 | 2025 | 2026E | 2027E | 2028E | 2029E |
|---|---|---|---|---|---|---|---|
| Net Income | $6.0B | $7.0B | $10.3B | $16.5B | $17.7B | $15.1B | $16.7B |
| EPS (Diluted) | $1.91 | $1.13 | $3.27 | $5.29 | $5.67 | $4.83 | $5.36 |
| YoY Growth | — | +18.1% | +45.8% | +60.9% | +7.1% | -14.7% | +10.7% |
| Net Margin | 13.0% | 13.0% | 17.5% | 25.6% | 24.9% | 19.3% | 19.8% |
| Metric | 2025A | 2026E | 2027E | 2028E | 2029E |
|---|---|---|---|---|---|
| Revenue | $58.7B | $64.5B | $71.1B | $78.1B | $84.3B |
| Net Income | $10.3B | $16.5B | $17.7B | $15.1B | $16.7B |
| EPS (Diluted) | $3.27 | $5.29 | $5.67 | $4.83 | $5.36 |
| Free Cash Flow | $11.8B | $23.4B | $26.6B | $30.1B | $33.4B |
Treat point estimates cautiously; use wider scenario ranges and position sizing discipline.
AstraZeneca PLC's projected EPS for the next fiscal year is $5.29. This estimate blends our quantitative model with Wall Street analyst consensus and carries a confidence score of 47/100. The model factors in revenue trajectory, margin path, and share buyback trends to arrive at this figure.
Our scenario-based model produces three price targets for AstraZeneca PLC: Bear case $34, Base case $361, and Bull case $272. These targets are derived by applying the median historical P/E ratio to forward EPS estimates under each growth scenario. They are not buy/sell recommendations.
AstraZeneca PLC's projected revenue growth for the next fiscal year is 9.9%, reaching approximately $64.5B in total revenue. Growth estimates are probability-weighted and blend analyst consensus with our CAGR extrapolation model. Outer years (FY+3, FY+4) fade toward industry median growth rates.
Accuracy depends on several measurable factors. Our model confidence score of 47/100 is computed from revenue predictability (25% weight), margin stability (20%), historical earnings beat rate (20%), data depth (15%), analyst coverage (10%), and model-consensus agreement (10%). Currently expanding margins support higher forecast reliability. No forecast model is perfect — always cross-reference with your own analysis.
AstraZeneca PLC's forward operating margin is estimated at 24.3% for the next fiscal year. The margin trend is currently "expanding". Our model tracks margin mean-reversion patterns and adjusts for sector-specific cost dynamics. Operating leverage is a key driver of EPS growth beyond top-line revenue expansion.
The v2 model uses a multi-step process: (1) Revenue is projected via blended CAGR with probability weighting, (2) Operating and net margins follow a mean-reversion path calibrated to sector norms, (3) EPS is derived from net income divided by projected diluted shares (accounting for buyback trends), (4) For FY+1 and FY+2, estimates are blended with analyst consensus based on coverage depth, (5) Price targets apply median historical P/E to forward EPS under bear/base/bull growth scenarios. All inputs are from public filings and third-party data providers.
The bear case ($34) assumes P25 revenue growth, worst-case margins, and multiple compression. Key risks include: unexpected margin contraction, revenue deceleration below model floor, regulatory headwinds, macro deterioration, or competitive disruption. A confidence score below 60 suggests higher estimate volatility. Always size positions according to the full scenario range, not just the base case.
Our model is below Wall Street consensus with a 48.5% gap. For FY+1, analyst estimates blend with our model at 23% analyst weight. By FY+3 and FY+4, estimates are purely model-driven as analyst coverage thins out at longer horizons.