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Stock Comparison

AVBP vs LLY vs MRK vs AZN vs IQV

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
AVBP
ArriVent BioPharma, Inc. Common Stock

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.22B
5Y Perf.+33.9%
LLY
Eli Lilly and Company

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$921.16B
5Y Perf.+51.0%
MRK
Merck & Co., Inc.

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$277.34B
5Y Perf.-7.0%
AZN
AstraZeneca PLC

Drug Manufacturers - General

HealthcareNASDAQ • GB
Market Cap$282.96B
5Y Perf.+37.9%
IQV
IQVIA Holdings Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$30.32B
5Y Perf.-14.2%

AVBP vs LLY vs MRK vs AZN vs IQV — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
AVBP logoAVBP
LLY logoLLY
MRK logoMRK
AZN logoAZN
IQV logoIQV
IndustryBiotechnologyDrug Manufacturers - GeneralDrug Manufacturers - GeneralDrug Manufacturers - GeneralMedical - Diagnostics & Research
Market Cap$1.22B$921.16B$277.34B$282.96B$30.32B
Revenue (TTM)$0.00$72.25B$64.93B$60.44B$16.63B
Net Income (TTM)$-166M$25.27B$18.25B$10.39B$1.39B
Gross Margin83.5%74.2%81.7%26.1%
Operating Margin45.9%41.1%23.7%13.9%
Forward P/E28.2x21.9x17.7x14.1x
Total Debt$14K$42.50B$50.53B$29.70B$16.17B
Cash & Equiv.$46M$7.16B$14.56B$5.71B$1.98B

AVBP vs LLY vs MRK vs AZN vs IQVLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

AVBP
LLY
MRK
AZN
IQV
StockJan 24May 26Return
ArriVent BioPharma,… (AVBP)100133.9+33.9%
Eli Lilly and Compa… (LLY)100151.0+51.0%
Merck & Co., Inc. (MRK)10093.0-7.0%
AstraZeneca PLC (AZN)100137.9+37.9%
IQVIA Holdings Inc. (IQV)10085.8-14.2%

Price return only. Dividends and distributions are not included.

Quick Verdict: AVBP vs LLY vs MRK vs AZN vs IQV

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: LLY and MRK are tied at the top with 3 categories each (5-stock set) — the right choice depends on your priorities. Merck & Co., Inc. is the stronger pick specifically for capital preservation and lower volatility and dividend income and shareholder returns. IQV also leads in specific categories worth noting. As sector peers, any of these can serve as alternatives in the same allocation.
AVBP
ArriVent BioPharma, Inc. Common Stock
The Healthcare Pick

AVBP lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
LLY
Eli Lilly and Company
The Growth Play

LLY carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.

  • Rev growth 44.7%, EPS growth 96.0%, 3Y rev CAGR 31.7%
  • 12.4% 10Y total return vs AZN's 268.6%
  • 44.7% revenue growth vs AVBP's -42.5%
  • 35.0% margin vs IQV's 8.3%
Best for: growth exposure and long-term compounding
MRK
Merck & Co., Inc.
The Income Pick

MRK is the #2 pick in this set and the best alternative if income & stability and sleep-well-at-night is your priority.

  • Dividend streak 14 yrs, beta 0.48, yield 2.9%
  • Lower volatility, beta 0.48, Low D/E 96.0%, current ratio 1.54x
  • Beta 0.48, yield 2.9%, current ratio 1.54x
  • Beta 0.48 vs IQV's 1.33, lower leverage
Best for: income & stability and sleep-well-at-night
AZN
AstraZeneca PLC
The Lower-Volatility Pick

Among these 5 stocks, AZN doesn't own a clear edge in any measured category.

Best for: healthcare exposure
IQV
IQVIA Holdings Inc.
The Value Pick

IQV ranks third and is worth considering specifically for valuation efficiency.

  • PEG 0.35 vs MRK's 1.03
  • Lower P/E (14.1x vs 17.7x), PEG 0.35 vs 0.81
Best for: valuation efficiency
See the full category breakdown
CategoryWinnerWhy
GrowthLLY logoLLY44.7% revenue growth vs AVBP's -42.5%
ValueIQV logoIQVLower P/E (14.1x vs 17.7x), PEG 0.35 vs 0.81
Quality / MarginsLLY logoLLY35.0% margin vs IQV's 8.3%
Stability / SafetyMRK logoMRKBeta 0.48 vs IQV's 1.33, lower leverage
DividendsMRK logoMRK2.9% yield, 14-year raise streak, vs LLY's 0.6%, (2 stocks pay no dividend)
Momentum (1Y)MRK logoMRK+46.1% vs IQV's +16.5%
Efficiency (ROA)LLY logoLLY22.7% ROA vs AVBP's -58.1%

AVBP vs LLY vs MRK vs AZN vs IQV — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

AVBPArriVent BioPharma, Inc. Common Stock

Segment breakdown not available.

LLYEli Lilly and Company
FY 2025
Product
93.5%$61.0B
Collaboration and Other Revenue
6.5%$4.2B
MRKMerck & Co., Inc.
FY 2025
Pharmaceutical segment
89.4%$58.1B
Animal Health segment
9.8%$6.4B
Other Segments
0.8%$515M
AZNAstraZeneca PLC
FY 2025
Total Oncology
23.9%$23.7B
CVRM
12.9%$12.8B
Rare Disease
9.2%$9.1B
Farxiga
8.5%$8.4B
Tagrisso
7.3%$7.3B
Imfinzi
6.1%$6.1B
Ultomiris
4.8%$4.7B
Other (22)
27.3%$27.1B
IQVIQVIA Holdings Inc.
FY 2025
Research And Development Solutions
54.5%$8.9B
Technology And Analytics Solutions
40.6%$6.6B
Contract Sales And Medical Solutions
4.8%$788M

AVBP vs LLY vs MRK vs AZN vs IQV — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLLLYLAGGINGAZN

Income & Cash Flow (Last 12 Months)

LLY leads this category, winning 5 of 6 comparable metrics.

LLY and AVBP operate at a comparable scale, with $72.2B and $0 in trailing revenue. LLY is the more profitable business, keeping 35.0% of every revenue dollar as net income compared to IQV's 8.3%. On growth, LLY holds the edge at +55.5% YoY revenue growth, suggesting stronger near-term business momentum.

MetricAVBP logoAVBPArriVent BioPharm…LLY logoLLYEli Lilly and Com…MRK logoMRKMerck & Co., Inc.AZN logoAZNAstraZeneca PLCIQV logoIQVIQVIA Holdings In…
RevenueTrailing 12 months$0$72.2B$64.9B$60.4B$16.6B
EBITDAEarnings before interest/tax-$133M$34.7B$32.4B$20.1B$3.5B
Net IncomeAfter-tax profit-$166M$25.3B$18.3B$10.4B$1.4B
Free Cash FlowCash after capex-$161M$13.6B$12.4B$9.1B$2.7B
Gross MarginGross profit ÷ Revenue+83.5%+74.2%+81.7%+26.1%
Operating MarginEBIT ÷ Revenue+45.9%+41.1%+23.7%+13.9%
Net MarginNet income ÷ Revenue+35.0%+28.1%+17.2%+8.3%
FCF MarginFCF ÷ Revenue+18.8%+19.0%+15.1%+16.1%
Rev. Growth (YoY)Latest quarter vs prior year+55.5%+4.5%+12.5%+8.4%
EPS Growth (YoY)Latest quarter vs prior year-13.1%+169.9%-19.6%+5.3%+15.0%
LLY leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

IQV leads this category, winning 4 of 7 comparable metrics.

At 15.4x trailing earnings, MRK trades at a 64% valuation discount to LLY's 42.5x P/E. Adjusting for growth (PEG ratio), IQV offers better value at 0.56x vs LLY's 1.47x — a lower PEG means you pay less per unit of expected earnings growth.

MetricAVBP logoAVBPArriVent BioPharm…LLY logoLLYEli Lilly and Com…MRK logoMRKMerck & Co., Inc.AZN logoAZNAstraZeneca PLCIQV logoIQVIQVIA Holdings In…
Market CapShares × price$1.2B$921.2B$277.3B$283.0B$30.3B
Enterprise ValueMkt cap + debt − cash$1.2B$956.5B$313.3B$306.9B$44.5B
Trailing P/EPrice ÷ TTM EPS-6.68x42.48x15.42x27.91x22.79x
Forward P/EPrice ÷ next-FY EPS est.28.24x21.93x17.74x14.06x
PEG RatioP/E ÷ EPS growth rate1.47x0.73x1.28x0.56x
EV / EBITDAEnterprise value multiple30.60x10.68x15.76x12.97x
Price / SalesMarket cap ÷ Revenue14.13x4.27x4.82x1.86x
Price / BookPrice ÷ Book value/share3.61x32.99x5.35x5.85x4.67x
Price / FCFMarket cap ÷ FCF102.67x22.44x24.05x14.78x
IQV leads this category, winning 4 of 7 comparable metrics.

Profitability & Efficiency

LLY leads this category, winning 6 of 9 comparable metrics.

LLY delivers a 101.2% return on equity — every $100 of shareholder capital generates $101 in annual profit, vs $-62 for AVBP. AVBP carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to IQV's 2.44x. On the Piotroski fundamental quality scale (0–9), LLY scores 8/9 vs AVBP's 2/9, reflecting strong financial health.

MetricAVBP logoAVBPArriVent BioPharm…LLY logoLLYEli Lilly and Com…MRK logoMRKMerck & Co., Inc.AZN logoAZNAstraZeneca PLCIQV logoIQVIQVIA Holdings In…
ROE (TTM)Return on equity-62.5%+101.2%+36.1%+22.2%+22.1%
ROA (TTM)Return on assets-58.1%+22.7%+14.6%+9.1%+4.7%
ROICReturn on invested capital+41.8%+22.0%+14.9%+8.7%
ROCEReturn on capital employed+46.6%+23.8%+17.2%+11.0%
Piotroski ScoreFundamental quality 0–928484
Debt / EquityFinancial leverage0.00x1.60x0.96x0.61x2.44x
Net DebtTotal debt minus cash-$46M$35.3B$36.0B$24.0B$14.2B
Cash & Equiv.Liquid assets$46M$7.2B$14.6B$5.7B$2.0B
Total DebtShort + long-term debt$14,000$42.5B$50.5B$29.7B$16.2B
Interest CoverageEBIT ÷ Interest expense35.68x19.68x8.43x3.10x
LLY leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

LLY leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in LLY five years ago would be worth $51,115 today (with dividends reinvested), compared to $7,621 for IQV. Over the past 12 months, MRK leads with a +46.1% total return vs IQV's +16.5%. The 3-year compound annual growth rate (CAGR) favors LLY at 31.8% vs IQV's -2.0% — a key indicator of consistent wealth creation.

MetricAVBP logoAVBPArriVent BioPharm…LLY logoLLYEli Lilly and Com…MRK logoMRKMerck & Co., Inc.AZN logoAZNAstraZeneca PLCIQV logoIQVIQVIA Holdings In…
YTD ReturnYear-to-date+38.7%-9.6%+6.3%+1.1%-20.7%
1-Year ReturnPast 12 months+45.7%+26.3%+46.1%+33.9%+16.5%
3-Year ReturnCumulative with dividends+44.2%+129.1%+2.9%+30.4%-5.9%
5-Year ReturnCumulative with dividends+44.3%+411.1%+70.2%+82.2%-23.8%
10-Year ReturnCumulative with dividends+44.2%+1237.7%+166.5%+268.6%+166.5%
CAGR (3Y)Annualised 3-year return+13.0%+31.8%+0.9%+9.3%-2.0%
LLY leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — AVBP and MRK each lead in 1 of 2 comparable metrics.

MRK is the less volatile stock with a 0.48 beta — it tends to amplify market swings less than IQV's 1.33 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. AVBP currently trades 89.8% from its 52-week high vs IQV's 72.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricAVBP logoAVBPArriVent BioPharm…LLY logoLLYEli Lilly and Com…MRK logoMRKMerck & Co., Inc.AZN logoAZNAstraZeneca PLCIQV logoIQVIQVIA Holdings In…
Beta (5Y)Sensitivity to S&P 5001.21x0.71x0.48x0.67x1.33x
52-Week HighHighest price in past year$32.14$1133.95$125.14$212.71$247.05
52-Week LowLowest price in past year$16.10$623.78$73.31$91.44$134.65
% of 52W HighCurrent price vs 52-week peak+89.8%+86.0%+89.7%+85.8%+72.3%
RSI (14)Momentum oscillator 0–10057.461.446.739.158.5
Avg Volume (50D)Average daily shares traded509K2.6M7.3M1.9M1.6M
Evenly matched — AVBP and MRK each lead in 1 of 2 comparable metrics.

Analyst Outlook

MRK leads this category, winning 2 of 2 comparable metrics.

Analyst consensus: AVBP as "Buy", LLY as "Buy", MRK as "Buy", AZN as "Buy", IQV as "Buy". Consensus price targets imply 52.5% upside for AVBP (target: $44) vs 15.2% for MRK (target: $129). For income investors, MRK offers the higher dividend yield at 2.90% vs LLY's 0.61%.

MetricAVBP logoAVBPArriVent BioPharm…LLY logoLLYEli Lilly and Com…MRK logoMRKMerck & Co., Inc.AZN logoAZNAstraZeneca PLCIQV logoIQVIQVIA Holdings In…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$44.00$1258.47$129.31$211.00$225.63
# AnalystsCovering analysts645374144
Dividend YieldAnnual dividend ÷ price+0.6%+2.9%+1.8%
Dividend StreakConsecutive years of raises111442
Dividend / ShareAnnual DPS$6.00$3.26$3.25
Buyback YieldShare repurchases ÷ mkt cap0.0%+0.4%+1.8%+0.3%+4.1%
MRK leads this category, winning 2 of 2 comparable metrics.
Key Takeaway

LLY leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). IQV leads in 1 (Valuation Metrics). 1 tied.

Best OverallEli Lilly and Company (LLY)Leads 3 of 6 categories
Loading custom metrics...

AVBP vs LLY vs MRK vs AZN vs IQV: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is AVBP or LLY or MRK or AZN or IQV a better buy right now?

For growth investors, Eli Lilly and Company (LLY) is the stronger pick with 44.

7% revenue growth year-over-year, versus 1. 2% for Merck & Co. , Inc. (MRK). Merck & Co. , Inc. (MRK) offers the better valuation at 15. 4x trailing P/E (21. 9x forward), making it the more compelling value choice. Analysts rate ArriVent BioPharma, Inc. Common Stock (AVBP) a "Buy" — based on 6 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — AVBP or LLY or MRK or AZN or IQV?

On trailing P/E, Merck & Co.

, Inc. (MRK) is the cheapest at 15. 4x versus Eli Lilly and Company at 42. 5x. On forward P/E, IQVIA Holdings Inc. is actually cheaper at 14. 1x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: IQVIA Holdings Inc. wins at 0. 35x versus Merck & Co. , Inc. 's 1. 03x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — AVBP or LLY or MRK or AZN or IQV?

Over the past 5 years, Eli Lilly and Company (LLY) delivered a total return of +411.

1%, compared to -23. 8% for IQVIA Holdings Inc. (IQV). Over 10 years, the gap is even starker: LLY returned +1238% versus AVBP's +44. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — AVBP or LLY or MRK or AZN or IQV?

By beta (market sensitivity over 5 years), Merck & Co.

, Inc. (MRK) is the lower-risk stock at 0. 48β versus IQVIA Holdings Inc. 's 1. 33β — meaning IQV is approximately 180% more volatile than MRK relative to the S&P 500. On balance sheet safety, ArriVent BioPharma, Inc. Common Stock (AVBP) carries a lower debt/equity ratio of 0% versus 2% for IQVIA Holdings Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — AVBP or LLY or MRK or AZN or IQV?

By revenue growth (latest reported year), Eli Lilly and Company (LLY) is pulling ahead at 44.

7% versus 1. 2% for Merck & Co. , Inc. (MRK). On earnings-per-share growth, the picture is similar: AstraZeneca PLC grew EPS 190. 7% year-over-year, compared to -68. 8% for ArriVent BioPharma, Inc. Common Stock. Over a 3-year CAGR, LLY leads at 31. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — AVBP or LLY or MRK or AZN or IQV?

Eli Lilly and Company (LLY) is the more profitable company, earning 31.

7% net margin versus 0. 0% for ArriVent BioPharma, Inc. Common Stock — meaning it keeps 31. 7% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: LLY leads at 45. 6% versus 0. 0% for AVBP. At the gross margin level — before operating expenses — LLY leads at 83. 8%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is AVBP or LLY or MRK or AZN or IQV more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, IQVIA Holdings Inc. (IQV) is the more undervalued stock at a PEG of 0. 35x versus Merck & Co. , Inc. 's 1. 03x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, IQVIA Holdings Inc. (IQV) trades at 14. 1x forward P/E versus 28. 2x for Eli Lilly and Company — 14. 2x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for AVBP: 52. 5% to $44. 00.

08

Which pays a better dividend — AVBP or LLY or MRK or AZN or IQV?

In this comparison, MRK (2.

9% yield), AZN (1. 8% yield), LLY (0. 6% yield) pay a dividend. AVBP, IQV do not pay a meaningful dividend and should not be held primarily for income.

09

Is AVBP or LLY or MRK or AZN or IQV better for a retirement portfolio?

For long-horizon retirement investors, Eli Lilly and Company (LLY) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

71), 0. 6% yield, +1238% 10Y return). Both have compounded well over 10 years (LLY: +1238%, IQV: +166. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between AVBP and LLY and MRK and AZN and IQV?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: AVBP is a small-cap quality compounder stock; LLY is a large-cap high-growth stock; MRK is a large-cap deep-value stock; AZN is a large-cap quality compounder stock; IQV is a mid-cap quality compounder stock. LLY, MRK, AZN pay a dividend while AVBP, IQV do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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