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BHST vs SIGA vs NVAX vs GILD vs MRNA

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
BHST
BioHarvest Sciences Inc. Common Stock

Agricultural Inputs

Basic MaterialsNASDAQ • CA
Market Cap$93M
5Y Perf.-13.1%
SIGA
SIGA Technologies, Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$339M
5Y Perf.-34.5%
NVAX
Novavax, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.50B
5Y Perf.-4.0%
GILD
Gilead Sciences, Inc.

Drug Manufacturers - General

HealthcareNASDAQ • US
Market Cap$166.40B
5Y Perf.+50.9%
MRNA
Moderna, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$19.25B
5Y Perf.-10.7%

BHST vs SIGA vs NVAX vs GILD vs MRNA — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
BHST logoBHST
SIGA logoSIGA
NVAX logoNVAX
GILD logoGILD
MRNA logoMRNA
IndustryAgricultural InputsDrug Manufacturers - Specialty & GenericBiotechnologyDrug Manufacturers - GeneralBiotechnology
Market Cap$93M$339M$1.50B$166.40B$19.25B
Revenue (TTM)$33M$94M$596M$29.73B$2.23B
Net Income (TTM)$-12M$-4.04T$-88M$9.22B$-3.19B
Gross Margin59.2%61.8%84.6%63.0%-13.9%
Operating Margin-18.8%27.7%-11.2%38.2%-153.3%
Forward P/E2.8x3.6x15.7x
Total Debt$14M$595K$249M$24.59B$1.92B
Cash & Equiv.$2M$155M$241M$7.56B$2.60B

BHST vs SIGA vs NVAX vs GILD vs MRNALong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

BHST
SIGA
NVAX
GILD
MRNA
StockOct 24May 26Return
BioHarvest Sciences… (BHST)10086.9-13.1%
SIGA Technologies, … (SIGA)10065.5-34.5%
Novavax, Inc. (NVAX)10096.0-4.0%
Gilead Sciences, In… (GILD)100150.9+50.9%
Moderna, Inc. (MRNA)10089.3-10.7%

Price return only. Dividends and distributions are not included.

Quick Verdict: BHST vs SIGA vs NVAX vs GILD vs MRNA

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: GILD leads in 3 of 7 categories (5-stock set), making it the strongest pick for profitability and margin quality and capital preservation and lower volatility. SIGA Technologies, Inc. is the stronger pick specifically for valuation and capital efficiency and dividend income and shareholder returns. BHST and MRNA also each lead in at least one category. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
BHST
BioHarvest Sciences Inc. Common Stock
The Growth Play

BHST ranks third and is worth considering specifically for growth exposure.

  • Rev growth 98.8%, EPS growth 14.0%, 3Y rev CAGR 128.8%
  • 98.8% revenue growth vs MRNA's -39.2%
Best for: growth exposure
SIGA
SIGA Technologies, Inc.
The Income Pick

SIGA is the #2 pick in this set and the best alternative if income & stability and long-term compounding is your priority.

  • Dividend streak 4 yrs, beta 1.15, yield 12.7%
  • 7.6% 10Y total return vs GILD's 87.8%
  • Lower volatility, beta 1.15, Low D/E 0.3%, current ratio 11.83x
  • Beta 1.15, yield 12.7%, current ratio 11.83x
Best for: income & stability and long-term compounding
NVAX
Novavax, Inc.
The Value Angle

Among these 5 stocks, NVAX doesn't own a clear edge in any measured category.

Best for: healthcare exposure
GILD
Gilead Sciences, Inc.
The Quality Compounder

GILD carries the broadest edge in this set and is the clearest fit for quality and stability.

  • 31.0% margin vs SIGA's -43K%
  • Beta 0.66 vs NVAX's 2.11
  • 16.1% ROA vs BHST's -41.5%, ROIC 23.4% vs -70.4%
Best for: quality and stability
MRNA
Moderna, Inc.
The Momentum Pick

MRNA is the clearest fit if your priority is momentum.

  • +101.7% vs BHST's -35.7%
Best for: momentum
See the full category breakdown
CategoryWinnerWhy
GrowthBHST logoBHST98.8% revenue growth vs MRNA's -39.2%
ValueSIGA logoSIGABetter valuation composite
Quality / MarginsGILD logoGILD31.0% margin vs SIGA's -43K%
Stability / SafetyGILD logoGILDBeta 0.66 vs NVAX's 2.11
DividendsSIGA logoSIGA12.7% yield, 4-year raise streak, vs GILD's 2.4%, (3 stocks pay no dividend)
Momentum (1Y)MRNA logoMRNA+101.7% vs BHST's -35.7%
Efficiency (ROA)GILD logoGILD16.1% ROA vs BHST's -41.5%, ROIC 23.4% vs -70.4%

BHST vs SIGA vs NVAX vs GILD vs MRNA — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

BHSTBioHarvest Sciences Inc. Common Stock
FY 2024
Total
50.3%$25M
Products
49.7%$25M
SIGASIGA Technologies, Inc.
FY 2025
Product Sales and Supportive Services
93.1%$88M
Research and Development
6.9%$7M
NVAXNovavax, Inc.
FY 2025
Product
50.0%$685M
Nuvaxovid Sales
45.6%$625M
Supply Sales
4.4%$60M
GILDGilead Sciences, Inc.
FY 2025
Products, Other HIV
79.7%$20.8B
Cell Therapy Products, Total Cell Therapy Product Sales
8.4%$2.2B
Trodelvy
5.4%$1.4B
Veklury
3.5%$911M
Other Products, Total Other product sales
3.1%$799M
MRNAModerna, Inc.
FY 2025
Product Sales
100.0%$3.3B

BHST vs SIGA vs NVAX vs GILD vs MRNA — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLGILDLAGGINGMRNA

Income & Cash Flow (Last 12 Months)

GILD leads this category, winning 3 of 6 comparable metrics.

GILD is the larger business by revenue, generating $29.7B annually — 908.8x BHST's $33M. GILD is the more profitable business, keeping 31.0% of every revenue dollar as net income compared to SIGA's -43117.4%. On growth, MRNA holds the edge at +2.6% YoY revenue growth, suggesting stronger near-term business momentum.

MetricBHST logoBHSTBioHarvest Scienc…SIGA logoSIGASIGA Technologies…NVAX logoNVAXNovavax, Inc.GILD logoGILDGilead Sciences, …MRNA logoMRNAModerna, Inc.
RevenueTrailing 12 months$33M$94M$596M$29.7B$2.2B
EBITDAEarnings before interest/tax-$5M$26M-$47M$12.1B-$3.2B
Net IncomeAfter-tax profit-$12M-$4.04T-$88M$9.2B-$3.2B
Free Cash FlowCash after capex-$10M$33M-$96M$10.3B-$1.6B
Gross MarginGross profit ÷ Revenue+59.2%+61.8%+84.6%+63.0%-13.9%
Operating MarginEBIT ÷ Revenue-18.8%+27.7%-11.2%+38.2%-153.3%
Net MarginNet income ÷ Revenue-36.3%-43117.4%-14.7%+31.0%-143.6%
FCF MarginFCF ÷ Revenue-30.8%+35.2%-16.1%+34.8%-71.1%
Rev. Growth (YoY)Latest quarter vs prior year+38.7%-11.3%-79.1%+4.4%+2.6%
EPS Growth (YoY)Latest quarter vs prior year+12.5%-102.0%+54.8%-34.9%
GILD leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

SIGA leads this category, winning 3 of 6 comparable metrics.

At 3.6x trailing earnings, NVAX trades at a 82% valuation discount to GILD's 19.8x P/E. On an enterprise value basis, NVAX's 2.6x EV/EBITDA is more attractive than GILD's 17.0x.

MetricBHST logoBHSTBioHarvest Scienc…SIGA logoSIGASIGA Technologies…NVAX logoNVAXNovavax, Inc.GILD logoGILDGilead Sciences, …MRNA logoMRNAModerna, Inc.
Market CapShares × price$93M$339M$1.5B$166.4B$19.3B
Enterprise ValueMkt cap + debt − cash$105M$185M$1.5B$183.4B$18.6B
Trailing P/EPrice ÷ TTM EPS-5.14x14.33x3.63x19.77x-6.69x
Forward P/EPrice ÷ next-FY EPS est.2.78x15.69x
PEG RatioP/E ÷ EPS growth rate0.15x
EV / EBITDAEnterprise value multiple7.60x2.56x16.95x
Price / SalesMarket cap ÷ Revenue3.70x3.58x1.34x5.65x9.90x
Price / BookPrice ÷ Book value/share50.04x1.70x7.44x2.18x
Price / FCFMarket cap ÷ FCF6.96x17.60x
SIGA leads this category, winning 3 of 6 comparable metrics.

Profitability & Efficiency

GILD leads this category, winning 4 of 9 comparable metrics.

GILD delivers a 42.3% return on equity — every $100 of shareholder capital generates $42 in annual profit, vs $-12 for BHST. SIGA carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to BHST's 10.39x. On the Piotroski fundamental quality scale (0–9), GILD scores 9/9 vs MRNA's 3/9, reflecting strong financial health.

MetricBHST logoBHSTBioHarvest Scienc…SIGA logoSIGASIGA Technologies…NVAX logoNVAXNovavax, Inc.GILD logoGILDGilead Sciences, …MRNA logoMRNAModerna, Inc.
ROE (TTM)Return on equity-12.0%-10.7%+42.3%-36.7%
ROA (TTM)Return on assets-41.5%-7.4%-7.4%+16.1%-26.6%
ROICReturn on invested capital-70.4%+33.7%+23.4%-26.1%
ROCEReturn on capital employed-65.1%+11.3%+100.4%+25.1%-27.6%
Piotroski ScoreFundamental quality 0–965593
Debt / EquityFinancial leverage10.39x0.00x1.09x0.22x
Net DebtTotal debt minus cash$11M-$154M$8M$17.0B-$679M
Cash & Equiv.Liquid assets$2M$155M$241M$7.6B$2.6B
Total DebtShort + long-term debt$14M$595,169$249M$24.6B$1.9B
Interest CoverageEBIT ÷ Interest expense-1.10x-5.10x8.87x-1803.00x
GILD leads this category, winning 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

GILD leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in GILD five years ago would be worth $22,418 today (with dividends reinvested), compared to $524 for NVAX. Over the past 12 months, MRNA leads with a +101.7% total return vs BHST's -35.7%. The 3-year compound annual growth rate (CAGR) favors GILD at 22.2% vs MRNA's -28.3% — a key indicator of consistent wealth creation.

MetricBHST logoBHSTBioHarvest Scienc…SIGA logoSIGASIGA Technologies…NVAX logoNVAXNovavax, Inc.GILD logoGILDGilead Sciences, …MRNA logoMRNAModerna, Inc.
YTD ReturnYear-to-date-21.1%-15.0%+29.5%+10.9%+57.3%
1-Year ReturnPast 12 months-35.7%+1.5%+55.1%+38.8%+101.7%
3-Year ReturnCumulative with dividends-17.8%+22.2%+23.9%+82.4%-63.2%
5-Year ReturnCumulative with dividends-17.8%+1.4%-94.8%+124.2%-70.2%
10-Year ReturnCumulative with dividends-17.8%+764.0%-90.4%+87.8%+161.0%
CAGR (3Y)Annualised 3-year return-6.3%+6.9%+7.4%+22.2%-28.3%
GILD leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

GILD leads this category, winning 2 of 2 comparable metrics.

GILD is the less volatile stock with a 0.66 beta — it tends to amplify market swings less than NVAX's 2.11 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. GILD currently trades 85.2% from its 52-week high vs BHST's 32.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricBHST logoBHSTBioHarvest Scienc…SIGA logoSIGASIGA Technologies…NVAX logoNVAXNovavax, Inc.GILD logoGILDGilead Sciences, …MRNA logoMRNAModerna, Inc.
Beta (5Y)Sensitivity to S&P 5001.05x1.15x2.11x0.66x1.82x
52-Week HighHighest price in past year$12.80$9.62$11.97$157.29$59.55
52-Week LowLowest price in past year$4.10$4.29$5.80$95.30$22.28
% of 52W HighCurrent price vs 52-week peak+32.1%+49.2%+77.1%+85.2%+81.5%
RSI (14)Momentum oscillator 0–10042.547.064.452.647.0
Avg Volume (50D)Average daily shares traded26K688K4.4M5.8M6.9M
GILD leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Evenly matched — SIGA and GILD each lead in 1 of 2 comparable metrics.

Analyst consensus: BHST as "Buy", SIGA as "Buy", NVAX as "Buy", GILD as "Buy", MRNA as "Hold". Consensus price targets imply 143.3% upside for BHST (target: $10) vs -25.8% for MRNA (target: $36). For income investors, SIGA offers the higher dividend yield at 12.73% vs GILD's 2.38%.

MetricBHST logoBHSTBioHarvest Scienc…SIGA logoSIGASIGA Technologies…NVAX logoNVAXNovavax, Inc.GILD logoGILDGilead Sciences, …MRNA logoMRNAModerna, Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyHold
Price TargetConsensus 12-month target$10.00$18.00$161.88$36.00
# AnalystsCovering analysts11235827
Dividend YieldAnnual dividend ÷ price+12.7%+2.4%
Dividend StreakConsecutive years of raises41110
Dividend / ShareAnnual DPS$0.60$3.19
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%+0.3%+1.2%0.0%
Evenly matched — SIGA and GILD each lead in 1 of 2 comparable metrics.
Key Takeaway

GILD leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). SIGA leads in 1 (Valuation Metrics). 1 tied.

Best OverallGilead Sciences, Inc. (GILD)Leads 4 of 6 categories
Loading custom metrics...

BHST vs SIGA vs NVAX vs GILD vs MRNA: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is BHST or SIGA or NVAX or GILD or MRNA a better buy right now?

For growth investors, BioHarvest Sciences Inc.

Common Stock (BHST) is the stronger pick with 98. 8% revenue growth year-over-year, versus -39. 2% for Moderna, Inc. (MRNA). Novavax, Inc. (NVAX) offers the better valuation at 3. 6x trailing P/E, making it the more compelling value choice. Analysts rate BioHarvest Sciences Inc. Common Stock (BHST) a "Buy" — based on 1 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — BHST or SIGA or NVAX or GILD or MRNA?

On trailing P/E, Novavax, Inc.

(NVAX) is the cheapest at 3. 6x versus Gilead Sciences, Inc. at 19. 8x. On forward P/E, SIGA Technologies, Inc. is actually cheaper at 2. 8x — notably different from the trailing picture, reflecting expected earnings growth.

03

Which is the better long-term investment — BHST or SIGA or NVAX or GILD or MRNA?

Over the past 5 years, Gilead Sciences, Inc.

(GILD) delivered a total return of +124. 2%, compared to -94. 8% for Novavax, Inc. (NVAX). Over 10 years, the gap is even starker: SIGA returned +764. 0% versus NVAX's -90. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — BHST or SIGA or NVAX or GILD or MRNA?

By beta (market sensitivity over 5 years), Gilead Sciences, Inc.

(GILD) is the lower-risk stock at 0. 66β versus Novavax, Inc. 's 2. 11β — meaning NVAX is approximately 220% more volatile than GILD relative to the S&P 500. On balance sheet safety, SIGA Technologies, Inc. (SIGA) carries a lower debt/equity ratio of 0% versus 10% for BioHarvest Sciences Inc. Common Stock — giving it more financial flexibility in a downturn.

05

Which is growing faster — BHST or SIGA or NVAX or GILD or MRNA?

By revenue growth (latest reported year), BioHarvest Sciences Inc.

Common Stock (BHST) is pulling ahead at 98. 8% versus -39. 2% for Moderna, Inc. (MRNA). On earnings-per-share growth, the picture is similar: Gilead Sciences, Inc. grew EPS 1684% year-over-year, compared to -60. 2% for SIGA Technologies, Inc.. Over a 3-year CAGR, BHST leads at 128. 8% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — BHST or SIGA or NVAX or GILD or MRNA?

Novavax, Inc.

(NVAX) is the more profitable company, earning 39. 2% net margin versus -145. 2% for Moderna, Inc. — meaning it keeps 39. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: NVAX leads at 50. 1% versus -158. 1% for MRNA. At the gross margin level — before operating expenses — NVAX leads at 93. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is BHST or SIGA or NVAX or GILD or MRNA more undervalued right now?

On forward earnings alone, SIGA Technologies, Inc.

(SIGA) trades at 2. 8x forward P/E versus 15. 7x for Gilead Sciences, Inc. — 12. 9x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for BHST: 143. 3% to $10. 00.

08

Which pays a better dividend — BHST or SIGA or NVAX or GILD or MRNA?

In this comparison, SIGA (12.

7% yield), GILD (2. 4% yield) pay a dividend. BHST, NVAX, MRNA do not pay a meaningful dividend and should not be held primarily for income.

09

Is BHST or SIGA or NVAX or GILD or MRNA better for a retirement portfolio?

For long-horizon retirement investors, SIGA Technologies, Inc.

(SIGA) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 15), 12. 7% yield, +764. 0% 10Y return). Novavax, Inc. (NVAX) carries a higher beta of 2. 11 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (SIGA: +764. 0%, NVAX: -90. 4%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between BHST and SIGA and NVAX and GILD and MRNA?

These companies operate in different sectors (BHST (Basic Materials) and SIGA (Healthcare) and NVAX (Healthcare) and GILD (Healthcare) and MRNA (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: BHST is a small-cap high-growth stock; SIGA is a small-cap deep-value stock; NVAX is a small-cap high-growth stock; GILD is a mid-cap quality compounder stock; MRNA is a mid-cap quality compounder stock. SIGA, GILD pay a dividend while BHST, NVAX, MRNA do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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