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GOVX vs DVAX vs NVAX vs SIGA vs MRNA

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
GOVX
GeoVax Labs, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$2M
5Y Perf.-96.5%
DVAX
Dynavax Technologies Corporation

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$1.82B
5Y Perf.+258.6%
NVAX
Novavax, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.66B
5Y Perf.-90.7%
SIGA
SIGA Technologies, Inc.

Drug Manufacturers - Specialty & Generic

HealthcareNASDAQ • US
Market Cap$344M
5Y Perf.-30.1%
MRNA
Moderna, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$21.55B
5Y Perf.-23.2%

GOVX vs DVAX vs NVAX vs SIGA vs MRNA — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
GOVX logoGOVX
DVAX logoDVAX
NVAX logoNVAX
SIGA logoSIGA
MRNA logoMRNA
IndustryBiotechnologyDrug Manufacturers - Specialty & GenericBiotechnologyDrug Manufacturers - Specialty & GenericBiotechnology
Market Cap$2M$1.82B$1.66B$344M$21.55B
Revenue (TTM)$2M$331M$596M$94M$2.23B
Net Income (TTM)$-21M$-43M$-88M$-4.04T$-3.19B
Gross Margin100.0%83.2%84.6%61.8%-13.9%
Operating Margin-8.7%3.2%-11.2%27.7%-153.3%
Forward P/E31.6x4.0x2.8x
Total Debt$843.17B$254M$249M$595K$1.92B
Cash & Equiv.$6M$96M$241M$155M$2.60B

GOVX vs DVAX vs NVAX vs SIGA vs MRNALong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

GOVX
DVAX
NVAX
SIGA
MRNA
StockSep 20May 26Return
GeoVax Labs, Inc. (GOVX)1003.5-96.5%
Dynavax Technologie… (DVAX)100358.6+258.6%
Novavax, Inc. (NVAX)1009.3-90.7%
SIGA Technologies, … (SIGA)10069.9-30.1%
Moderna, Inc. (MRNA)10076.8-23.2%

Price return only. Dividends and distributions are not included.

Quick Verdict: GOVX vs DVAX vs NVAX vs SIGA vs MRNA

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: DVAX and SIGA are tied at the top with 2 categories each (5-stock set) — the right choice depends on your priorities. SIGA Technologies, Inc. is the stronger pick specifically for valuation and capital efficiency and dividend income and shareholder returns. GOVX, NVAX, and MRNA also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
GOVX
GeoVax Labs, Inc.
The Niche Pick

GOVX ranks third and is worth considering specifically for efficiency.

  • -0.0% ROA vs MRNA's -26.6%, ROIC -0.0% vs -26.1%
Best for: efficiency
DVAX
Dynavax Technologies Corporation
The Defensive Pick

DVAX has the current edge in this matchup, primarily because of its strength in defensive.

  • Beta 0.80, current ratio 10.80x
  • -13.1% margin vs SIGA's -43K%
  • Beta 0.80 vs GOVX's 2.27
Best for: defensive
NVAX
Novavax, Inc.
The Growth Play

NVAX is the clearest fit if your priority is growth exposure.

  • Rev growth 64.7%, EPS growth 306.5%, 3Y rev CAGR -11.1%
  • 64.7% revenue growth vs MRNA's -39.2%
Best for: growth exposure
SIGA
SIGA Technologies, Inc.
The Income Pick

SIGA is the #2 pick in this set and the best alternative if income & stability and long-term compounding is your priority.

  • Dividend streak 4 yrs, beta 1.09, yield 12.5%
  • 7.7% 10Y total return vs DVAX's 2.9%
  • Lower volatility, beta 1.09, Low D/E 0.3%, current ratio 11.83x
  • Better valuation composite
Best for: income & stability and long-term compounding
MRNA
Moderna, Inc.
The Momentum Pick

MRNA is the clearest fit if your priority is momentum.

  • +122.9% vs SIGA's -0.7%
Best for: momentum
See the full category breakdown
CategoryWinnerWhy
GrowthNVAX logoNVAX64.7% revenue growth vs MRNA's -39.2%
ValueSIGA logoSIGABetter valuation composite
Quality / MarginsDVAX logoDVAX-13.1% margin vs SIGA's -43K%
Stability / SafetyDVAX logoDVAXBeta 0.80 vs GOVX's 2.27
DividendsSIGA logoSIGA12.5% yield; 4-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)MRNA logoMRNA+122.9% vs SIGA's -0.7%
Efficiency (ROA)GOVX logoGOVX-0.0% ROA vs MRNA's -26.6%, ROIC -0.0% vs -26.1%

GOVX vs DVAX vs NVAX vs SIGA vs MRNA — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

GOVXGeoVax Labs, Inc.
FY 2022
NIH Grants
100.0%$81,526
DVAXDynavax Technologies Corporation
FY 2024
H E P L I S A V B
96.8%$268M
Other Revenue
3.2%$9M
NVAXNovavax, Inc.
FY 2025
Product
50.0%$685M
Nuvaxovid Sales
45.6%$625M
Supply Sales
4.4%$60M
SIGASIGA Technologies, Inc.
FY 2025
Product Sales and Supportive Services
93.1%$88M
Research and Development
6.9%$7M
MRNAModerna, Inc.
FY 2025
Product Sales
100.0%$3.3B

GOVX vs DVAX vs NVAX vs SIGA vs MRNA — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLDVAXLAGGINGMRNA

Income & Cash Flow (Last 12 Months)

Evenly matched — DVAX and SIGA each lead in 2 of 6 comparable metrics.

MRNA is the larger business by revenue, generating $2.2B annually — 893.9x GOVX's $2M. DVAX is the more profitable business, keeping -13.1% of every revenue dollar as net income compared to SIGA's -43117.4%. On growth, MRNA holds the edge at +2.6% YoY revenue growth, suggesting stronger near-term business momentum.

MetricGOVX logoGOVXGeoVax Labs, Inc.DVAX logoDVAXDynavax Technolog…NVAX logoNVAXNovavax, Inc.SIGA logoSIGASIGA Technologies…MRNA logoMRNAModerna, Inc.
RevenueTrailing 12 months$2M$331M$596M$94M$2.2B
EBITDAEarnings before interest/tax-$22M$19M-$47M$26M-$3.2B
Net IncomeAfter-tax profit-$21M-$43M-$88M-$4.04T-$3.2B
Free Cash FlowCash after capex-$21M$81M-$97M$27M-$1.6B
Gross MarginGross profit ÷ Revenue+100.0%+83.2%+84.6%+61.8%-13.9%
Operating MarginEBIT ÷ Revenue-8.7%+3.2%-11.2%+27.7%-153.3%
Net MarginNet income ÷ Revenue-8.6%-13.1%-14.7%-43117.4%-143.6%
FCF MarginFCF ÷ Revenue-8.6%+24.4%-16.3%+29.2%-71.1%
Rev. Growth (YoY)Latest quarter vs prior year-100.0%+17.7%-79.1%-11.3%+2.6%
EPS Growth (YoY)Latest quarter vs prior year+86.9%+90.9%-102.0%-34.9%
Evenly matched — DVAX and SIGA each lead in 2 of 6 comparable metrics.

Valuation Metrics

Evenly matched — GOVX and SIGA each lead in 2 of 6 comparable metrics.

At 4.0x trailing earnings, NVAX trades at a 95% valuation discount to DVAX's 77.5x P/E. On an enterprise value basis, NVAX's 2.8x EV/EBITDA is more attractive than DVAX's 503.2x.

MetricGOVX logoGOVXGeoVax Labs, Inc.DVAX logoDVAXDynavax Technolog…NVAX logoNVAXNovavax, Inc.SIGA logoSIGASIGA Technologies…MRNA logoMRNAModerna, Inc.
Market CapShares × price$2M$1.8B$1.7B$344M$21.6B
Enterprise ValueMkt cap + debt − cash$843.2B$2.0B$1.7B$190M$20.9B
Trailing P/EPrice ÷ TTM EPS-0.07x77.50x3.98x14.55x-7.49x
Forward P/EPrice ÷ next-FY EPS est.31.59x2.82x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple503.23x2.83x7.81x
Price / SalesMarket cap ÷ Revenue0.64x6.56x1.48x3.64x11.09x
Price / BookPrice ÷ Book value/share0.00x3.46x1.73x2.44x
Price / FCFMarket cap ÷ FCF30.24x7.98x
Evenly matched — GOVX and SIGA each lead in 2 of 6 comparable metrics.

Profitability & Efficiency

SIGA leads this category, winning 3 of 9 comparable metrics.

GOVX delivers a -0.0% return on equity — every $100 of shareholder capital generates $-0 in annual profit, vs $-37 for MRNA. SIGA carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to DVAX's 0.43x. On the Piotroski fundamental quality scale (0–9), DVAX scores 6/9 vs MRNA's 3/9, reflecting solid financial health.

MetricGOVX logoGOVXGeoVax Labs, Inc.DVAX logoDVAXDynavax Technolog…NVAX logoNVAXNovavax, Inc.SIGA logoSIGASIGA Technologies…MRNA logoMRNAModerna, Inc.
ROE (TTM)Return on equity-0.0%-8.1%-10.7%-36.7%
ROA (TTM)Return on assets-0.0%-4.6%-7.4%-7.4%-26.6%
ROICReturn on invested capital-0.0%-0.4%+33.7%-26.1%
ROCEReturn on capital employed-0.0%-0.4%+100.4%+11.3%-27.6%
Piotroski ScoreFundamental quality 0–946553
Debt / EquityFinancial leverage0.22x0.43x0.00x0.22x
Net DebtTotal debt minus cash$843.2B$159M$8M-$154M-$679M
Cash & Equiv.Liquid assets$6M$96M$241M$155M$2.6B
Total DebtShort + long-term debt$843.2B$254M$249M$595,169$1.9B
Interest CoverageEBIT ÷ Interest expense-5.28x-6.40x-1803.00x
SIGA leads this category, winning 3 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

DVAX leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in DVAX five years ago would be worth $19,620 today (with dividends reinvested), compared to $201 for GOVX. Over the past 12 months, MRNA leads with a +122.9% total return vs SIGA's -0.7%. The 3-year compound annual growth rate (CAGR) favors DVAX at 12.4% vs GOVX's -44.9% — a key indicator of consistent wealth creation.

MetricGOVX logoGOVXGeoVax Labs, Inc.DVAX logoDVAXDynavax Technolog…NVAX logoNVAXNovavax, Inc.SIGA logoSIGASIGA Technologies…MRNA logoMRNAModerna, Inc.
YTD ReturnYear-to-date+706.8%+0.8%+41.8%-13.9%+76.1%
1-Year ReturnPast 12 months+72.2%+60.0%+51.8%-0.7%+122.9%
3-Year ReturnCumulative with dividends-83.3%+42.1%+35.7%+23.5%-58.7%
5-Year ReturnCumulative with dividends-98.0%+96.2%-93.7%+7.9%-65.7%
10-Year ReturnCumulative with dividends-96.2%+2.9%-89.4%+772.1%+192.2%
CAGR (3Y)Annualised 3-year return-44.9%+12.4%+10.7%+7.3%-25.6%
DVAX leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

DVAX leads this category, winning 2 of 2 comparable metrics.

DVAX is the less volatile stock with a 0.80 beta — it tends to amplify market swings less than GOVX's 2.27 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. DVAX currently trades 98.5% from its 52-week high vs GOVX's 38.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricGOVX logoGOVXGeoVax Labs, Inc.DVAX logoDVAXDynavax Technolog…NVAX logoNVAXNovavax, Inc.SIGA logoSIGASIGA Technologies…MRNA logoMRNAModerna, Inc.
Beta (5Y)Sensitivity to S&P 5002.27x0.80x2.22x1.09x1.81x
52-Week HighHighest price in past year$4.40$15.73$11.97$9.62$59.55
52-Week LowLowest price in past year$0.12$9.20$5.80$4.29$22.28
% of 52W HighCurrent price vs 52-week peak+38.0%+98.5%+84.5%+49.9%+91.3%
RSI (14)Momentum oscillator 0–10071.175.761.848.546.3
Avg Volume (50D)Average daily shares traded227K5.7M4.2M703K7.2M
DVAX leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

SIGA leads this category, winning 1 of 1 comparable metric.

Analyst consensus: DVAX as "Buy", NVAX as "Buy", SIGA as "Buy", MRNA as "Hold". Consensus price targets imply 78.0% upside for NVAX (target: $18) vs -28.2% for MRNA (target: $39). SIGA is the only dividend payer here at 12.54% yield — a key consideration for income-focused portfolios.

MetricGOVX logoGOVXGeoVax Labs, Inc.DVAX logoDVAXDynavax Technolog…NVAX logoNVAXNovavax, Inc.SIGA logoSIGASIGA Technologies…MRNA logoMRNAModerna, Inc.
Analyst RatingConsensus buy/hold/sellBuyBuyBuyHold
Price TargetConsensus 12-month target$27.00$18.00$39.00
# AnalystsCovering analysts1123127
Dividend YieldAnnual dividend ÷ price+12.5%
Dividend StreakConsecutive years of raises140
Dividend / ShareAnnual DPS$0.60
Buyback YieldShare repurchases ÷ mkt cap0.0%+5.5%+0.3%0.0%0.0%
SIGA leads this category, winning 1 of 1 comparable metric.
Key Takeaway

SIGA leads in 2 of 6 categories (Profitability & Efficiency, Analyst Outlook). DVAX leads in 2 (Total Returns, Risk & Volatility). 2 tied.

Best OverallDynavax Technologies Corpor… (DVAX)Leads 2 of 6 categories
Loading custom metrics...

GOVX vs DVAX vs NVAX vs SIGA vs MRNA: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is GOVX or DVAX or NVAX or SIGA or MRNA a better buy right now?

For growth investors, Novavax, Inc.

(NVAX) is the stronger pick with 64. 7% revenue growth year-over-year, versus -39. 2% for Moderna, Inc. (MRNA). Novavax, Inc. (NVAX) offers the better valuation at 4. 0x trailing P/E, making it the more compelling value choice. Analysts rate Dynavax Technologies Corporation (DVAX) a "Buy" — based on 11 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — GOVX or DVAX or NVAX or SIGA or MRNA?

On trailing P/E, Novavax, Inc.

(NVAX) is the cheapest at 4. 0x versus Dynavax Technologies Corporation at 77. 5x. On forward P/E, SIGA Technologies, Inc. is actually cheaper at 2. 8x — notably different from the trailing picture, reflecting expected earnings growth.

03

Which is the better long-term investment — GOVX or DVAX or NVAX or SIGA or MRNA?

Over the past 5 years, Dynavax Technologies Corporation (DVAX) delivered a total return of +96.

2%, compared to -98. 0% for GeoVax Labs, Inc. (GOVX). Over 10 years, the gap is even starker: SIGA returned +772. 1% versus GOVX's -96. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — GOVX or DVAX or NVAX or SIGA or MRNA?

By beta (market sensitivity over 5 years), Dynavax Technologies Corporation (DVAX) is the lower-risk stock at 0.

80β versus GeoVax Labs, Inc. 's 2. 27β — meaning GOVX is approximately 185% more volatile than DVAX relative to the S&P 500. On balance sheet safety, SIGA Technologies, Inc. (SIGA) carries a lower debt/equity ratio of 0% versus 43% for Dynavax Technologies Corporation — giving it more financial flexibility in a downturn.

05

Which is growing faster — GOVX or DVAX or NVAX or SIGA or MRNA?

By revenue growth (latest reported year), Novavax, Inc.

(NVAX) is pulling ahead at 64. 7% versus -39. 2% for Moderna, Inc. (MRNA). On earnings-per-share growth, the picture is similar: Dynavax Technologies Corporation grew EPS 503. 2% year-over-year, compared to -60. 2% for SIGA Technologies, Inc.. Over a 3-year CAGR, GOVX leads at 212. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — GOVX or DVAX or NVAX or SIGA or MRNA?

Novavax, Inc.

(NVAX) is the more profitable company, earning 39. 2% net margin versus -862. 3% for GeoVax Labs, Inc. — meaning it keeps 39. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: NVAX leads at 50. 1% versus -869. 3% for GOVX. At the gross margin level — before operating expenses — GOVX leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is GOVX or DVAX or NVAX or SIGA or MRNA more undervalued right now?

On forward earnings alone, SIGA Technologies, Inc.

(SIGA) trades at 2. 8x forward P/E versus 31. 6x for Dynavax Technologies Corporation — 28. 8x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for NVAX: 78. 0% to $18. 00.

08

Which pays a better dividend — GOVX or DVAX or NVAX or SIGA or MRNA?

In this comparison, SIGA (12.

5% yield) pays a dividend. GOVX, DVAX, NVAX, MRNA do not pay a meaningful dividend and should not be held primarily for income.

09

Is GOVX or DVAX or NVAX or SIGA or MRNA better for a retirement portfolio?

For long-horizon retirement investors, SIGA Technologies, Inc.

(SIGA) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1. 09), 12. 5% yield, +772. 1% 10Y return). GeoVax Labs, Inc. (GOVX) carries a higher beta of 2. 27 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (SIGA: +772. 1%, GOVX: -96. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between GOVX and DVAX and NVAX and SIGA and MRNA?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: GOVX is a small-cap quality compounder stock; DVAX is a small-cap high-growth stock; NVAX is a small-cap high-growth stock; SIGA is a small-cap deep-value stock; MRNA is a mid-cap quality compounder stock. SIGA pays a dividend while GOVX, DVAX, NVAX, MRNA do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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GOVX

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  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 60%
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High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 8%
  • Gross Margin > 49%
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NVAX

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  • Market Cap > $100B
  • Gross Margin > 50%
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SIGA

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  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 37%
  • Dividend Yield > 5.0%
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High-Growth Disruptor

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 131%
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Beat Both

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Revenue Growth>
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(GOVX: -100.0% · DVAX: 17.7%)

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