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ICLR vs PRA vs CRL vs HCI vs IQV

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
ICLR
ICON Public Limited Company

Medical - Diagnostics & Research

HealthcareNASDAQ • IE
Market Cap$9.51B
5Y Perf.-26.1%
PRA
ProAssurance Corporation

Insurance - Property & Casualty

Financial ServicesNYSE • US
Market Cap$1.27B
5Y Perf.+79.0%
CRL
Charles River Laboratories International, Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$8.76B
5Y Perf.-1.1%
HCI
HCI Group, Inc.

Insurance - Property & Casualty

Financial ServicesNYSE • US
Market Cap$1.98B
5Y Perf.+239.4%
IQV
IQVIA Holdings Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$30.33B
5Y Perf.+19.5%

ICLR vs PRA vs CRL vs HCI vs IQV — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
ICLR logoICLR
PRA logoPRA
CRL logoCRL
HCI logoHCI
IQV logoIQV
IndustryMedical - Diagnostics & ResearchInsurance - Property & CasualtyMedical - Diagnostics & ResearchInsurance - Property & CasualtyMedical - Diagnostics & Research
Market Cap$9.51B$1.27B$8.76B$1.98B$30.33B
Revenue (TTM)$8.10B$1.08B$4.03B$927M$16.63B
Net Income (TTM)$599M$65M$-185M$303M$1.39B
Gross Margin26.9%25.5%31.9%66.5%26.1%
Operating Margin12.2%8.4%11.8%47.9%13.9%
Forward P/E10.7x21.7x16.0x8.9x14.0x
Total Debt$3.60B$435M$3.07B$68M$16.17B
Cash & Equiv.$539M$36M$214M$1.21B$1.98B

ICLR vs PRA vs CRL vs HCI vs IQVLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

ICLR
PRA
CRL
HCI
IQV
StockMay 20May 26Return
ICON Public Limited… (ICLR)10073.9-26.1%
ProAssurance Corpor… (PRA)100179.0+79.0%
Charles River Labor… (CRL)10098.9-1.1%
HCI Group, Inc. (HCI)100339.4+239.4%
IQVIA Holdings Inc. (IQV)100119.5+19.5%

Price return only. Dividends and distributions are not included.

Quick Verdict: ICLR vs PRA vs CRL vs HCI vs IQV

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: HCI leads in 5 of 7 categories (5-stock set), making it the strongest pick for growth and revenue expansion and valuation and capital efficiency. ProAssurance Corporation is the stronger pick specifically for capital preservation and lower volatility. CRL also leads in specific categories worth noting. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
ICLR
ICON Public Limited Company
The Value Angle

ICLR lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
PRA
ProAssurance Corporation
The Insurance Pick

PRA is the #2 pick in this set and the best alternative if sleep-well-at-night and defensive is your priority.

  • Lower volatility, beta 0.05, Low D/E 32.2%, current ratio 1.33x
  • Beta 0.05, current ratio 1.33x
  • Beta 0.05 vs ICLR's 1.64, lower leverage
Best for: sleep-well-at-night and defensive
CRL
Charles River Laboratories International, Inc.
The Momentum Pick

CRL ranks third and is worth considering specifically for momentum.

  • +25.7% vs ICLR's -10.1%
Best for: momentum
HCI
HCI Group, Inc.
The Insurance Pick

HCI carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.

  • Dividend streak 2 yrs, beta 0.38, yield 1.0%
  • Rev growth 20.2%, EPS growth 179.8%, 3Y rev CAGR 22.3%
  • 434.8% 10Y total return vs IQV's 166.6%
  • PEG 0.19 vs ICLR's 1.53
Best for: income & stability and growth exposure
IQV
IQVIA Holdings Inc.
The Value Angle

Among these 5 stocks, IQV doesn't own a clear edge in any measured category.

Best for: healthcare exposure
See the full category breakdown
CategoryWinnerWhy
GrowthHCI logoHCI20.2% revenue growth vs PRA's -2.7%
ValueHCI logoHCILower P/E (8.9x vs 14.0x), PEG 0.19 vs 0.34
Quality / MarginsHCI logoHCI32.6% margin vs CRL's -4.6%
Stability / SafetyPRA logoPRABeta 0.05 vs ICLR's 1.64, lower leverage
DividendsHCI logoHCI1.0% yield; 2-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)CRL logoCRL+25.7% vs ICLR's -10.1%
Efficiency (ROA)HCI logoHCI12.7% ROA vs CRL's -2.5%, ROIC 6.8% vs 6.3%

ICLR vs PRA vs CRL vs HCI vs IQV — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

ICLRICON Public Limited Company
FY 2012
Clinical Research
92.2%$1.0B
Central Laboratory
7.8%$87M
PRAProAssurance Corporation
FY 2025
Specialty Property and Casualty
77.5%$724M
Workers' Compensation Insurance Segment
17.6%$164M
Segregated Portfolio Cell Reinsurance
4.9%$46M
CRLCharles River Laboratories International, Inc.
FY 2025
Discovery and Safety Assessment
59.8%$2.4B
Research Models and Services
21.1%$846M
Manufacturing Support
19.1%$766M
HCIHCI Group, Inc.
FY 2025
Real Estate Operations
100.0%$15M
IQVIQVIA Holdings Inc.
FY 2025
Research And Development Solutions
54.5%$8.9B
Technology And Analytics Solutions
40.6%$6.6B
Contract Sales And Medical Solutions
4.8%$788M

ICLR vs PRA vs CRL vs HCI vs IQV — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLHCILAGGINGIQV

Income & Cash Flow (Last 12 Months)

HCI leads this category, winning 5 of 6 comparable metrics.

IQV is the larger business by revenue, generating $16.6B annually — 17.9x HCI's $927M. HCI is the more profitable business, keeping 32.6% of every revenue dollar as net income compared to CRL's -4.6%. On growth, HCI holds the edge at +11.9% YoY revenue growth, suggesting stronger near-term business momentum.

MetricICLR logoICLRICON Public Limit…PRA logoPRAProAssurance Corp…CRL logoCRLCharles River Lab…HCI logoHCIHCI Group, Inc.IQV logoIQVIQVIA Holdings In…
RevenueTrailing 12 months$8.1B$1.1B$4.0B$927M$16.6B
EBITDAEarnings before interest/tax$1.4B$101M$824M$454M$3.5B
Net IncomeAfter-tax profit$599M$65M-$185M$303M$1.4B
Free Cash FlowCash after capex$996M-$17M$391M$282M$2.7B
Gross MarginGross profit ÷ Revenue+26.9%+25.5%+31.9%+66.5%+26.1%
Operating MarginEBIT ÷ Revenue+12.2%+8.4%+11.8%+47.9%+13.9%
Net MarginNet income ÷ Revenue+7.4%+6.0%-4.6%+32.6%+8.3%
FCF MarginFCF ÷ Revenue+12.3%-1.6%+9.7%+30.4%+16.1%
Rev. Growth (YoY)Latest quarter vs prior year+0.6%-2.0%+1.2%+11.9%+8.4%
EPS Growth (YoY)Latest quarter vs prior year-98.7%+2.5%-160.0%+23.4%+15.0%
HCI leads this category, winning 5 of 6 comparable metrics.

Valuation Metrics

HCI leads this category, winning 4 of 7 comparable metrics.

At 6.1x trailing earnings, HCI trades at a 75% valuation discount to PRA's 24.9x P/E. Adjusting for growth (PEG ratio), HCI offers better value at 0.13x vs ICLR's 1.86x — a lower PEG means you pay less per unit of expected earnings growth.

MetricICLR logoICLRICON Public Limit…PRA logoPRAProAssurance Corp…CRL logoCRLCharles River Lab…HCI logoHCIHCI Group, Inc.IQV logoIQVIQVIA Holdings In…
Market CapShares × price$9.5B$1.3B$8.8B$2.0B$30.3B
Enterprise ValueMkt cap + debt − cash$12.6B$1.7B$11.6B$836M$44.5B
Trailing P/EPrice ÷ TTM EPS13.06x24.95x-61.04x6.12x22.79x
Forward P/EPrice ÷ next-FY EPS est.10.73x21.73x16.00x8.94x13.96x
PEG RatioP/E ÷ EPS growth rate1.86x0.13x0.56x
EV / EBITDAEnterprise value multiple7.92x19.51x12.75x1.90x12.98x
Price / SalesMarket cap ÷ Revenue1.15x1.16x2.18x2.20x1.86x
Price / BookPrice ÷ Book value/share1.09x0.95x2.74x1.76x4.68x
Price / FCFMarket cap ÷ FCF8.50x16.90x4.45x14.79x
HCI leads this category, winning 4 of 7 comparable metrics.

Profitability & Efficiency

HCI leads this category, winning 9 of 9 comparable metrics.

HCI delivers a 30.8% return on equity — every $100 of shareholder capital generates $31 in annual profit, vs $-6 for CRL. HCI carries lower financial leverage with a 0.06x debt-to-equity ratio, signaling a more conservative balance sheet compared to IQV's 2.44x. On the Piotroski fundamental quality scale (0–9), HCI scores 8/9 vs PRA's 3/9, reflecting strong financial health.

MetricICLR logoICLRICON Public Limit…PRA logoPRAProAssurance Corp…CRL logoCRLCharles River Lab…HCI logoHCIHCI Group, Inc.IQV logoIQVIQVIA Holdings In…
ROE (TTM)Return on equity+6.3%+5.0%-5.7%+30.8%+22.1%
ROA (TTM)Return on assets+3.6%+1.2%-2.5%+12.7%+4.7%
ROICReturn on invested capital+6.5%+3.2%+6.3%+6.8%+8.7%
ROCEReturn on capital employed+7.8%+4.0%+8.1%+40.6%+11.0%
Piotroski ScoreFundamental quality 0–973484
Debt / EquityFinancial leverage0.38x0.32x0.95x0.06x2.44x
Net DebtTotal debt minus cash$3.1B$399M$2.9B-$1.1B$14.2B
Cash & Equiv.Liquid assets$539M$36M$214M$1.2B$2.0B
Total DebtShort + long-term debt$3.6B$435M$3.1B$68M$16.2B
Interest CoverageEBIT ÷ Interest expense3.96x4.53x4.29x67.37x3.10x
HCI leads this category, winning 9 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

HCI leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in HCI five years ago would be worth $21,408 today (with dividends reinvested), compared to $5,336 for CRL. Over the past 12 months, CRL leads with a +25.7% total return vs ICLR's -10.1%. The 3-year compound annual growth rate (CAGR) favors HCI at 45.6% vs ICLR's -13.1% — a key indicator of consistent wealth creation.

MetricICLR logoICLRICON Public Limit…PRA logoPRAProAssurance Corp…CRL logoCRLCharles River Lab…HCI logoHCIHCI Group, Inc.IQV logoIQVIQVIA Holdings In…
YTD ReturnYear-to-date-34.0%+2.8%-12.3%-17.0%-20.7%
1-Year ReturnPast 12 months-10.1%+7.8%+25.7%-0.7%+16.6%
3-Year ReturnCumulative with dividends-34.4%+32.4%-6.5%+208.3%-5.9%
5-Year ReturnCumulative with dividends-44.8%+0.2%-46.6%+114.1%-22.8%
10-Year ReturnCumulative with dividends+90.2%-18.6%+114.0%+434.8%+166.6%
CAGR (3Y)Annualised 3-year return-13.1%+9.8%-2.2%+45.6%-2.0%
HCI leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

PRA leads this category, winning 2 of 2 comparable metrics.

PRA is the less volatile stock with a 0.05 beta — it tends to amplify market swings less than ICLR's 1.64 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. PRA currently trades 99.4% from its 52-week high vs ICLR's 59.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricICLR logoICLRICON Public Limit…PRA logoPRAProAssurance Corp…CRL logoCRLCharles River Lab…HCI logoHCIHCI Group, Inc.IQV logoIQVIQVIA Holdings In…
Beta (5Y)Sensitivity to S&P 5001.64x0.05x1.44x0.38x1.32x
52-Week HighHighest price in past year$211.00$24.85$228.88$210.50$247.05
52-Week LowLowest price in past year$66.57$22.72$132.58$136.37$134.65
% of 52W HighCurrent price vs 52-week peak+59.0%+99.4%+77.6%+72.3%+72.3%
RSI (14)Momentum oscillator 0–10062.849.157.446.660.3
Avg Volume (50D)Average daily shares traded1.1M798K792K167K1.5M
PRA leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Evenly matched — HCI and IQV each lead in 1 of 1 comparable metric.

Analyst consensus: ICLR as "Buy", PRA as "Hold", CRL as "Buy", HCI as "Buy", IQV as "Buy". Consensus price targets imply 25.2% upside for IQV (target: $224) vs -25.8% for PRA (target: $18). HCI is the only dividend payer here at 0.98% yield — a key consideration for income-focused portfolios.

MetricICLR logoICLRICON Public Limit…PRA logoPRAProAssurance Corp…CRL logoCRLCharles River Lab…HCI logoHCIHCI Group, Inc.IQV logoIQVIQVIA Holdings In…
Analyst RatingConsensus buy/hold/sellBuyHoldBuyBuyBuy
Price TargetConsensus 12-month target$152.13$18.33$206.43$126.50$223.75
# AnalystsCovering analysts3011361444
Dividend YieldAnnual dividend ÷ price+1.0%
Dividend StreakConsecutive years of raises0122
Dividend / ShareAnnual DPS$1.50
Buyback YieldShare repurchases ÷ mkt cap+5.3%0.0%+4.1%+0.1%+4.1%
Evenly matched — HCI and IQV each lead in 1 of 1 comparable metric.
Key Takeaway

HCI leads in 4 of 6 categories (Income & Cash Flow, Valuation Metrics). PRA leads in 1 (Risk & Volatility). 1 tied.

Best OverallHCI Group, Inc. (HCI)Leads 4 of 6 categories
Loading custom metrics...

ICLR vs PRA vs CRL vs HCI vs IQV: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is ICLR or PRA or CRL or HCI or IQV a better buy right now?

For growth investors, HCI Group, Inc.

(HCI) is the stronger pick with 20. 2% revenue growth year-over-year, versus -2. 7% for ProAssurance Corporation (PRA). HCI Group, Inc. (HCI) offers the better valuation at 6. 1x trailing P/E (8. 9x forward), making it the more compelling value choice. Analysts rate ICON Public Limited Company (ICLR) a "Buy" — based on 30 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — ICLR or PRA or CRL or HCI or IQV?

On trailing P/E, HCI Group, Inc.

(HCI) is the cheapest at 6. 1x versus ProAssurance Corporation at 24. 9x. On forward P/E, HCI Group, Inc. is actually cheaper at 8. 9x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: HCI Group, Inc. wins at 0. 19x versus ICON Public Limited Company's 1. 53x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — ICLR or PRA or CRL or HCI or IQV?

Over the past 5 years, HCI Group, Inc.

(HCI) delivered a total return of +114. 1%, compared to -46. 6% for Charles River Laboratories International, Inc. (CRL). Over 10 years, the gap is even starker: HCI returned +434. 8% versus PRA's -18. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — ICLR or PRA or CRL or HCI or IQV?

By beta (market sensitivity over 5 years), ProAssurance Corporation (PRA) is the lower-risk stock at 0.

05β versus ICON Public Limited Company's 1. 64β — meaning ICLR is approximately 3233% more volatile than PRA relative to the S&P 500. On balance sheet safety, HCI Group, Inc. (HCI) carries a lower debt/equity ratio of 6% versus 2% for IQVIA Holdings Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — ICLR or PRA or CRL or HCI or IQV?

By revenue growth (latest reported year), HCI Group, Inc.

(HCI) is pulling ahead at 20. 2% versus -2. 7% for ProAssurance Corporation (PRA). On earnings-per-share growth, the picture is similar: HCI Group, Inc. grew EPS 179. 8% year-over-year, compared to -1555. 0% for Charles River Laboratories International, Inc.. Over a 3-year CAGR, HCI leads at 22. 3% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — ICLR or PRA or CRL or HCI or IQV?

HCI Group, Inc.

(HCI) is the more profitable company, earning 33. 2% net margin versus -3. 6% for Charles River Laboratories International, Inc. — meaning it keeps 33. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HCI leads at 47. 7% versus 6. 6% for PRA. At the gross margin level — before operating expenses — HCI leads at 73. 2%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is ICLR or PRA or CRL or HCI or IQV more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, HCI Group, Inc. (HCI) is the more undervalued stock at a PEG of 0. 19x versus ICON Public Limited Company's 1. 53x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, HCI Group, Inc. (HCI) trades at 8. 9x forward P/E versus 21. 7x for ProAssurance Corporation — 12. 8x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for IQV: 25. 2% to $223. 75.

08

Which pays a better dividend — ICLR or PRA or CRL or HCI or IQV?

In this comparison, HCI (1.

0% yield) pays a dividend. ICLR, PRA, CRL, IQV do not pay a meaningful dividend and should not be held primarily for income.

09

Is ICLR or PRA or CRL or HCI or IQV better for a retirement portfolio?

For long-horizon retirement investors, HCI Group, Inc.

(HCI) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 38), 1. 0% yield, +434. 8% 10Y return). ICON Public Limited Company (ICLR) carries a higher beta of 1. 64 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (HCI: +434. 8%, ICLR: +90. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between ICLR and PRA and CRL and HCI and IQV?

These companies operate in different sectors (ICLR (Healthcare) and PRA (Financial Services) and CRL (Healthcare) and HCI (Financial Services) and IQV (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: ICLR is a small-cap deep-value stock; PRA is a small-cap quality compounder stock; CRL is a small-cap quality compounder stock; HCI is a small-cap high-growth stock; IQV is a mid-cap quality compounder stock. HCI pays a dividend while ICLR, PRA, CRL, IQV do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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ICLR

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Net Margin > 5%
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PRA

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  • Sector: Financial Services
  • Market Cap > $100B
  • Net Margin > 5%
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CRL

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  • Sector: Healthcare
  • Market Cap > $100B
  • Gross Margin > 19%
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HCI

Quality Mega-Cap Compounder

  • Sector: Financial Services
  • Market Cap > $100B
  • Revenue Growth > 5%
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IQV

Quality Business

  • Sector: Healthcare
  • Market Cap > $100B
  • Revenue Growth > 5%
  • Net Margin > 5%
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Custom Screen

Beat Both

Find stocks that outperform ICLR and PRA and CRL and HCI and IQV on the metrics below

Revenue Growth>
%
(ICLR: 0.6% · PRA: -2.0%)
Net Margin>
%
(ICLR: 7.4% · PRA: 6.0%)
P/E Ratio<
x
(ICLR: 13.1x · PRA: 24.9x)

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