Biotechnology
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SANA vs DBVT vs IMVT vs NVAX vs REGN
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
Biotechnology
SANA vs DBVT vs IMVT vs NVAX vs REGN — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $918M | $1712.35T | $5.53B | $1.50B | $73.68B |
| Revenue (TTM) | $0.00 | $0.00 | $0.00 | $596M | $14.92B |
| Net Income (TTM) | $-234M | $-168M | $-464M | $-88M | $4.42B |
| Gross Margin | — | — | — | 84.6% | 84.5% |
| Operating Margin | — | — | — | -11.2% | 24.3% |
| Forward P/E | — | — | — | 3.6x | 15.3x |
| Total Debt | $94M | $22M | $98K | $249M | $2.71B |
| Cash & Equiv. | $128M | $194M | $714M | $241M | $3.12B |
SANA vs DBVT vs IMVT vs NVAX vs REGN — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Feb 21 | May 26 | Return |
|---|---|---|---|
| Sana Biotechnology,… (SANA) | 100 | 11.4 | -88.6% |
| DBV Technologies S.… (DBVT) | 100 | 37.4 | -62.6% |
| Immunovant, Inc. (IMVT) | 100 | 172.5 | +72.5% |
| Novavax, Inc. (NVAX) | 100 | 4.0 | -96.0% |
| Regeneron Pharmaceu… (REGN) | 100 | 157.4 | +57.4% |
Price return only. Dividends and distributions are not included.
Quick Verdict: SANA vs DBVT vs IMVT vs NVAX vs REGN
Each card shows where this stock fits in a portfolio — not just who wins on paper.
SANA lags the leaders in this set but could rank higher in a more targeted comparison.
DBVT ranks third and is worth considering specifically for momentum.
- +110.4% vs REGN's +27.1%
IMVT is the clearest fit if your priority is long-term compounding.
- 173.6% 10Y total return vs REGN's 90.0%
NVAX is the #2 pick in this set and the best alternative if growth exposure is your priority.
- Rev growth 64.7%, EPS growth 306.5%, 3Y rev CAGR -11.1%
- 64.7% revenue growth vs DBVT's -100.0%
- Lower P/E (3.6x vs 15.3x)
REGN carries the broadest edge in this set and is the clearest fit for income & stability and sleep-well-at-night.
- Dividend streak 1 yrs, beta 0.81, yield 0.5%
- Lower volatility, beta 0.81, Low D/E 8.7%, current ratio 4.13x
- Beta 0.81, yield 0.5%, current ratio 4.13x
- 29.6% margin vs NVAX's -14.7%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 64.7% revenue growth vs DBVT's -100.0% | |
| Value | Lower P/E (3.6x vs 15.3x) | |
| Quality / Margins | 29.6% margin vs NVAX's -14.7% | |
| Stability / Safety | Beta 0.81 vs SANA's 2.69, lower leverage | |
| Dividends | 0.5% yield; 1-year raise streak; the other 4 pay no meaningful dividend | |
| Momentum (1Y) | +110.4% vs REGN's +27.1% | |
| Efficiency (ROA) | 11.1% ROA vs DBVT's -89.0% |
SANA vs DBVT vs IMVT vs NVAX vs REGN — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
Segment breakdown not available.
SANA vs DBVT vs IMVT vs NVAX vs REGN — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
REGN leads in 2 of 6 categories
NVAX leads 1 • IMVT leads 1 • SANA leads 0 • DBVT leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
REGN leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
REGN and IMVT operate at a comparable scale, with $14.9B and $0 in trailing revenue. REGN is the more profitable business, keeping 29.6% of every revenue dollar as net income compared to NVAX's -14.7%. On growth, REGN holds the edge at +19.0% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $0 | $0 | $596M | $14.9B |
| EBITDAEarnings before interest/tax | -$225M | -$112M | -$487M | -$47M | $4.2B |
| Net IncomeAfter-tax profit | -$234M | -$168M | -$464M | -$88M | $4.4B |
| Free Cash FlowCash after capex | -$159M | -$151M | -$423M | -$96M | $4.2B |
| Gross MarginGross profit ÷ Revenue | — | — | — | +84.6% | +84.5% |
| Operating MarginEBIT ÷ Revenue | — | — | — | -11.2% | +24.3% |
| Net MarginNet income ÷ Revenue | — | — | — | -14.7% | +29.6% |
| FCF MarginFCF ÷ Revenue | — | — | — | -16.1% | +27.9% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — | — | -79.1% | +19.0% |
| EPS Growth (YoY)Latest quarter vs prior year | +36.0% | +91.5% | +19.7% | -102.0% | -7.2% |
Valuation Metrics
NVAX leads this category, winning 2 of 4 comparable metrics.
Valuation Metrics
At 3.6x trailing earnings, NVAX trades at a 79% valuation discount to REGN's 17.1x P/E. On an enterprise value basis, NVAX's 2.6x EV/EBITDA is more attractive than REGN's 17.8x.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $918M | $1712.35T | $5.5B | $1.5B | $73.7B |
| Enterprise ValueMkt cap + debt − cash | $885M | $1712.35T | $4.8B | $1.5B | $73.3B |
| Trailing P/EPrice ÷ TTM EPS | -3.02x | -0.76x | -9.97x | 3.63x | 17.09x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | — | 15.35x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | 2.70x |
| EV / EBITDAEnterprise value multiple | — | — | — | 2.56x | 17.78x |
| Price / SalesMarket cap ÷ Revenue | — | — | — | 1.34x | 5.14x |
| Price / BookPrice ÷ Book value/share | 3.23x | 0.66x | 5.83x | — | 2.46x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — | 18.06x |
Profitability & Efficiency
REGN leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
REGN delivers a 14.3% return on equity — every $100 of shareholder capital generates $14 in annual profit, vs $-130 for DBVT. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to SANA's 0.38x. On the Piotroski fundamental quality scale (0–9), NVAX scores 5/9 vs IMVT's 2/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -120.0% | -130.2% | -47.1% | — | +14.3% |
| ROA (TTM)Return on assets | -53.8% | -89.0% | -44.1% | -7.4% | +11.1% |
| ROICReturn on invested capital | -86.1% | — | — | — | +8.9% |
| ROCEReturn on capital employed | -57.0% | -145.7% | -66.1% | +100.4% | +10.2% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 4 | 2 | 5 | 5 |
| Debt / EquityFinancial leverage | 0.38x | 0.13x | 0.00x | — | 0.09x |
| Net DebtTotal debt minus cash | -$33M | -$172M | -$714M | $8M | -$412M |
| Cash & Equiv.Liquid assets | $128M | $194M | $714M | $241M | $3.1B |
| Total DebtShort + long-term debt | $94M | $22M | $98,000 | $249M | $2.7B |
| Interest CoverageEBIT ÷ Interest expense | — | -189.82x | — | -5.10x | 108.44x |
Total Returns (Dividends Reinvested)
IMVT leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in IMVT five years ago would be worth $16,241 today (with dividends reinvested), compared to $524 for NVAX. Over the past 12 months, DBVT leads with a +110.4% total return vs REGN's +27.1%. The 3-year compound annual growth rate (CAGR) favors IMVT at 12.1% vs SANA's -14.2% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -16.5% | +4.9% | +5.1% | +29.5% | -8.5% |
| 1-Year ReturnPast 12 months | +105.9% | +110.4% | +96.1% | +55.1% | +27.1% |
| 3-Year ReturnCumulative with dividends | -36.8% | +19.7% | +40.9% | +23.9% | -5.1% |
| 5-Year ReturnCumulative with dividends | -80.7% | -69.1% | +62.4% | -94.8% | +43.6% |
| 10-Year ReturnCumulative with dividends | -90.0% | -87.0% | +173.6% | -90.4% | +90.0% |
| CAGR (3Y)Annualised 3-year return | -14.2% | +6.2% | +12.1% | +7.4% | -1.7% |
Risk & Volatility
Evenly matched — IMVT and REGN each lead in 1 of 2 comparable metrics.
Risk & Volatility
REGN is the less volatile stock with a 0.81 beta — it tends to amplify market swings less than SANA's 2.69 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 90.5% from its 52-week high vs SANA's 53.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 2.69x | 1.26x | 1.37x | 2.11x | 0.81x |
| 52-Week HighHighest price in past year | $6.55 | $26.18 | $30.09 | $11.97 | $821.11 |
| 52-Week LowLowest price in past year | $1.60 | $7.53 | $13.36 | $5.80 | $476.49 |
| % of 52W HighCurrent price vs 52-week peak | +53.4% | +76.3% | +90.5% | +77.1% | +86.4% |
| RSI (14)Momentum oscillator 0–100 | 59.0 | 48.1 | 60.2 | 64.4 | 44.9 |
| Avg Volume (50D)Average daily shares traded | 3.1M | 252K | 1.4M | 4.4M | 631K |
Analyst Outlook
Evenly matched — NVAX and REGN each lead in 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: SANA as "Buy", DBVT as "Buy", IMVT as "Buy", NVAX as "Buy", REGN as "Buy". Consensus price targets imply 147.7% upside for SANA (target: $9) vs 22.1% for REGN (target: $866). REGN is the only dividend payer here at 0.48% yield — a key consideration for income-focused portfolios.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $8.67 | $46.33 | $45.50 | $18.00 | $865.68 |
| # AnalystsCovering analysts | 11 | 15 | 23 | 23 | 48 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | +0.5% |
| Dividend StreakConsecutive years of raises | — | 0 | — | 1 | 1 |
| Dividend / ShareAnnual DPS | — | — | — | — | $3.41 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | +0.3% | +5.4% |
REGN leads in 2 of 6 categories (Income & Cash Flow, Profitability & Efficiency). NVAX leads in 1 (Valuation Metrics). 2 tied.
SANA vs DBVT vs IMVT vs NVAX vs REGN: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is SANA or DBVT or IMVT or NVAX or REGN a better buy right now?
For growth investors, Novavax, Inc.
(NVAX) is the stronger pick with 64. 7% revenue growth year-over-year, versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). Novavax, Inc. (NVAX) offers the better valuation at 3. 6x trailing P/E, making it the more compelling value choice. Analysts rate Sana Biotechnology, Inc. (SANA) a "Buy" — based on 11 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — SANA or DBVT or IMVT or NVAX or REGN?
On trailing P/E, Novavax, Inc.
(NVAX) is the cheapest at 3. 6x versus Regeneron Pharmaceuticals, Inc. at 17. 1x.
03Which is the better long-term investment — SANA or DBVT or IMVT or NVAX or REGN?
Over the past 5 years, Immunovant, Inc.
(IMVT) delivered a total return of +62. 4%, compared to -94. 8% for Novavax, Inc. (NVAX). Over 10 years, the gap is even starker: IMVT returned +173. 6% versus NVAX's -90. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — SANA or DBVT or IMVT or NVAX or REGN?
By beta (market sensitivity over 5 years), Regeneron Pharmaceuticals, Inc.
(REGN) is the lower-risk stock at 0. 81β versus Sana Biotechnology, Inc. 's 2. 69β — meaning SANA is approximately 234% more volatile than REGN relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 38% for Sana Biotechnology, Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — SANA or DBVT or IMVT or NVAX or REGN?
By revenue growth (latest reported year), Novavax, Inc.
(NVAX) is pulling ahead at 64. 7% versus 1. 0% for Regeneron Pharmaceuticals, Inc. (REGN). On earnings-per-share growth, the picture is similar: Novavax, Inc. grew EPS 306. 5% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, REGN leads at 5. 6% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — SANA or DBVT or IMVT or NVAX or REGN?
Novavax, Inc.
(NVAX) is the more profitable company, earning 39. 2% net margin versus 0. 0% for Immunovant, Inc. — meaning it keeps 39. 2% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: NVAX leads at 50. 1% versus 0. 0% for IMVT. At the gross margin level — before operating expenses — NVAX leads at 93. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is SANA or DBVT or IMVT or NVAX or REGN more undervalued right now?
Analyst consensus price targets imply the most upside for SANA: 147.
7% to $8. 67.
08Which pays a better dividend — SANA or DBVT or IMVT or NVAX or REGN?
In this comparison, REGN (0.
5% yield) pays a dividend. SANA, DBVT, IMVT, NVAX do not pay a meaningful dividend and should not be held primarily for income.
09Is SANA or DBVT or IMVT or NVAX or REGN better for a retirement portfolio?
For long-horizon retirement investors, Regeneron Pharmaceuticals, Inc.
(REGN) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 81)). Novavax, Inc. (NVAX) carries a higher beta of 2. 11 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (REGN: +90. 0%, NVAX: -90. 4%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between SANA and DBVT and IMVT and NVAX and REGN?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: SANA is a small-cap quality compounder stock; DBVT is a mega-cap quality compounder stock; IMVT is a small-cap quality compounder stock; NVAX is a small-cap high-growth stock; REGN is a mid-cap deep-value stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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