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Stock Comparison

UTHR vs DBVT vs HALO vs IQV vs ALNY

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
UTHR
United Therapeutics Corporation

Biotechnology

HealthcareNASDAQ • US
Market Cap$23.98B
5Y Perf.+379.0%
DBVT
DBV Technologies S.A.

Biotechnology

HealthcareNASDAQ • FR
Market Cap$1690.08T
5Y Perf.-59.3%
HALO
Halozyme Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$7.55B
5Y Perf.+164.2%
IQV
IQVIA Holdings Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$30.33B
5Y Perf.+19.5%
ALNY
Alnylam Pharmaceuticals, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$39.37B
5Y Perf.+118.1%

UTHR vs DBVT vs HALO vs IQV vs ALNY — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
UTHR logoUTHR
DBVT logoDBVT
HALO logoHALO
IQV logoIQV
ALNY logoALNY
IndustryBiotechnologyBiotechnologyBiotechnologyMedical - Diagnostics & ResearchBiotechnology
Market Cap$23.98B$1690.08T$7.55B$30.33B$39.37B
Revenue (TTM)$3.17B$0.00$1.40B$16.63B$4.29B
Net Income (TTM)$1.29B$-168M$317M$1.39B$577M
Gross Margin86.6%81.9%26.1%80.9%
Operating Margin45.3%58.4%13.9%17.5%
Forward P/E19.9x8.0x14.0x39.9x
Total Debt$0.00$22M$0.00$16.17B$1.28B
Cash & Equiv.$1.56B$194M$134M$1.98B$1.66B

UTHR vs DBVT vs HALO vs IQV vs ALNYLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

UTHR
DBVT
HALO
IQV
ALNY
StockMay 20May 26Return
United Therapeutics… (UTHR)100479.0+379.0%
DBV Technologies S.… (DBVT)10040.7-59.3%
Halozyme Therapeuti… (HALO)100264.2+164.2%
IQVIA Holdings Inc. (IQV)100119.5+19.5%
Alnylam Pharmaceuti… (ALNY)100218.1+118.1%

Price return only. Dividends and distributions are not included.

Quick Verdict: UTHR vs DBVT vs HALO vs IQV vs ALNY

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: UTHR leads in 3 of 7 categories (5-stock set), making it the strongest pick for profitability and margin quality and capital preservation and lower volatility. DBV Technologies S.A. is the stronger pick specifically for recent price momentum and sentiment. HALO and ALNY also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
UTHR
United Therapeutics Corporation
The Income Pick

UTHR carries the broadest edge in this set and is the clearest fit for income & stability and sleep-well-at-night.

  • Dividend streak 1 yrs, beta 0.21
  • Lower volatility, beta 0.21, current ratio 6.60x
  • Beta 0.21, current ratio 6.60x
  • 40.6% margin vs DBVT's 0.3%
Best for: income & stability and sleep-well-at-night
DBVT
DBV Technologies S.A.
The Momentum Pick

DBVT is the #2 pick in this set and the best alternative if momentum is your priority.

  • +100.5% vs HALO's -5.3%
Best for: momentum
HALO
Halozyme Therapeutics, Inc.
The Long-Run Compounder

HALO ranks third and is worth considering specifically for long-term compounding.

  • 5.6% 10Y total return vs ALNY's 410.4%
  • Lower P/E (8.0x vs 39.9x)
Best for: long-term compounding
IQV
IQVIA Holdings Inc.
The Value Pick

IQV is the clearest fit if your priority is valuation efficiency.

  • PEG 0.34 vs UTHR's 1.03
Best for: valuation efficiency
ALNY
Alnylam Pharmaceuticals, Inc.
The Growth Play

ALNY is the clearest fit if your priority is growth exposure.

  • Rev growth 65.2%, EPS growth 206.9%, 3Y rev CAGR 53.0%
  • 65.2% revenue growth vs DBVT's -100.0%
Best for: growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthALNY logoALNY65.2% revenue growth vs DBVT's -100.0%
ValueHALO logoHALOLower P/E (8.0x vs 39.9x)
Quality / MarginsUTHR logoUTHR40.6% margin vs DBVT's 0.3%
Stability / SafetyUTHR logoUTHRBeta 0.21 vs IQV's 1.32
DividendsTieNone of these 5 stocks pay a meaningful dividend
Momentum (1Y)DBVT logoDBVT+100.5% vs HALO's -5.3%
Efficiency (ROA)UTHR logoUTHR17.2% ROA vs DBVT's -89.0%

UTHR vs DBVT vs HALO vs IQV vs ALNY — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

UTHRUnited Therapeutics Corporation
FY 2025
Tyvaso
59.0%$1.9B
Remodulin
16.6%$527M
Orenitram
15.6%$497M
Unituxin
7.1%$227M
Adcirca
0.9%$30M
Product and Service, Other
0.8%$24M
DBVTDBV Technologies S.A.

Segment breakdown not available.

HALOHalozyme Therapeutics, Inc.
FY 2025
Royalty
53.6%$868M
Product
23.3%$376M
Collaborative Agreements
9.4%$152M
Bulk rHuPH20
8.2%$133M
Sales-based milestone
4.3%$70M
Upfront Fees
1.1%$18M
IQVIQVIA Holdings Inc.
FY 2025
Research And Development Solutions
54.5%$8.9B
Technology And Analytics Solutions
40.6%$6.6B
Contract Sales And Medical Solutions
4.8%$788M
ALNYAlnylam Pharmaceuticals, Inc.
FY 2025
GIVLAARI
64.1%$308M
ONPATTRO
35.9%$173M

UTHR vs DBVT vs HALO vs IQV vs ALNY — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLUTHRLAGGINGALNY

Income & Cash Flow (Last 12 Months)

Evenly matched — UTHR and HALO and ALNY each lead in 2 of 6 comparable metrics.

IQV and DBVT operate at a comparable scale, with $16.6B and $0 in trailing revenue. UTHR is the more profitable business, keeping 40.6% of every revenue dollar as net income compared to IQV's 8.3%. On growth, ALNY holds the edge at +96.4% YoY revenue growth, suggesting stronger near-term business momentum.

MetricUTHR logoUTHRUnited Therapeuti…DBVT logoDBVTDBV Technologies …HALO logoHALOHalozyme Therapeu…IQV logoIQVIQVIA Holdings In…ALNY logoALNYAlnylam Pharmaceu…
RevenueTrailing 12 months$3.2B$0$1.4B$16.6B$4.3B
EBITDAEarnings before interest/tax$1.5B-$112M$945M$3.5B$677M
Net IncomeAfter-tax profit$1.3B-$168M$317M$1.4B$577M
Free Cash FlowCash after capex$1.0B-$151M$645M$2.7B$641M
Gross MarginGross profit ÷ Revenue+86.6%+81.9%+26.1%+80.9%
Operating MarginEBIT ÷ Revenue+45.3%+58.4%+13.9%+17.5%
Net MarginNet income ÷ Revenue+40.6%+22.7%+8.3%+13.5%
FCF MarginFCF ÷ Revenue+32.1%+46.2%+16.1%+15.0%
Rev. Growth (YoY)Latest quarter vs prior year-1.6%+51.6%+8.4%+96.4%
EPS Growth (YoY)Latest quarter vs prior year-12.2%+91.5%-2.1%+15.0%+4.4%
Evenly matched — UTHR and HALO and ALNY each lead in 2 of 6 comparable metrics.

Valuation Metrics

HALO leads this category, winning 3 of 7 comparable metrics.

At 20.3x trailing earnings, UTHR trades at a 84% valuation discount to ALNY's 126.6x P/E. Adjusting for growth (PEG ratio), IQV offers better value at 0.56x vs HALO's 1.09x — a lower PEG means you pay less per unit of expected earnings growth.

MetricUTHR logoUTHRUnited Therapeuti…DBVT logoDBVTDBV Technologies …HALO logoHALOHalozyme Therapeu…IQV logoIQVIQVIA Holdings In…ALNY logoALNYAlnylam Pharmaceu…
Market CapShares × price$24.0B$1690.08T$7.6B$30.3B$39.4B
Enterprise ValueMkt cap + debt − cash$22.4B$1690.08T$7.4B$44.5B$39.0B
Trailing P/EPrice ÷ TTM EPS20.28x-0.75x25.05x22.79x126.63x
Forward P/EPrice ÷ next-FY EPS est.19.89x7.96x13.96x39.92x
PEG RatioP/E ÷ EPS growth rate1.05x1.09x0.56x
EV / EBITDAEnterprise value multiple13.99x8.20x12.98x69.97x
Price / SalesMarket cap ÷ Revenue7.53x5.41x1.86x10.60x
Price / BookPrice ÷ Book value/share3.81x0.65x162.76x4.68x50.35x
Price / FCFMarket cap ÷ FCF23.04x11.72x14.79x84.59x
HALO leads this category, winning 3 of 7 comparable metrics.

Profitability & Efficiency

UTHR leads this category, winning 5 of 9 comparable metrics.

HALO delivers a 6.5% return on equity — every $100 of shareholder capital generates $6 in annual profit, vs $-130 for DBVT. DBVT carries lower financial leverage with a 0.13x debt-to-equity ratio, signaling a more conservative balance sheet compared to IQV's 2.44x. On the Piotroski fundamental quality scale (0–9), UTHR scores 7/9 vs IQV's 4/9, reflecting strong financial health.

MetricUTHR logoUTHRUnited Therapeuti…DBVT logoDBVTDBV Technologies …HALO logoHALOHalozyme Therapeu…IQV logoIQVIQVIA Holdings In…ALNY logoALNYAlnylam Pharmaceu…
ROE (TTM)Return on equity+19.2%-130.2%+6.5%+22.1%+98.3%
ROA (TTM)Return on assets+17.2%-89.0%+12.5%+4.7%+11.8%
ROICReturn on invested capital+21.5%+73.4%+8.7%+33.4%
ROCEReturn on capital employed+21.8%-145.7%+38.2%+11.0%+15.3%
Piotroski ScoreFundamental quality 0–974546
Debt / EquityFinancial leverage0.13x2.44x1.62x
Net DebtTotal debt minus cash-$1.6B-$172M-$134M$14.2B-$379M
Cash & Equiv.Liquid assets$1.6B$194M$134M$2.0B$1.7B
Total DebtShort + long-term debt$0$22M$0$16.2B$1.3B
Interest CoverageEBIT ÷ Interest expense99.37x-189.82x46.08x3.10x2.02x
UTHR leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

UTHR leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in UTHR five years ago would be worth $29,752 today (with dividends reinvested), compared to $3,172 for DBVT. Over the past 12 months, DBVT leads with a +100.5% total return vs HALO's -5.3%. The 3-year compound annual growth rate (CAGR) favors UTHR at 39.0% vs IQV's -2.0% — a key indicator of consistent wealth creation.

MetricUTHR logoUTHRUnited Therapeuti…DBVT logoDBVTDBV Technologies …HALO logoHALOHalozyme Therapeu…IQV logoIQVIQVIA Holdings In…ALNY logoALNYAlnylam Pharmaceu…
YTD ReturnYear-to-date+13.7%+3.6%-8.8%-20.7%-26.3%
1-Year ReturnPast 12 months+83.4%+100.5%-5.3%+16.6%+14.2%
3-Year ReturnCumulative with dividends+168.4%+18.1%+111.8%-5.9%+40.5%
5-Year ReturnCumulative with dividends+197.5%-68.3%+39.1%-22.8%+129.4%
10-Year ReturnCumulative with dividends+406.2%-87.1%+559.7%+166.6%+410.4%
CAGR (3Y)Annualised 3-year return+39.0%+5.7%+28.4%-2.0%+12.0%
UTHR leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

UTHR leads this category, winning 2 of 2 comparable metrics.

UTHR is the less volatile stock with a 0.21 beta — it tends to amplify market swings less than IQV's 1.32 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. UTHR currently trades 92.7% from its 52-week high vs ALNY's 59.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricUTHR logoUTHRUnited Therapeuti…DBVT logoDBVTDBV Technologies …HALO logoHALOHalozyme Therapeu…IQV logoIQVIQVIA Holdings In…ALNY logoALNYAlnylam Pharmaceu…
Beta (5Y)Sensitivity to S&P 5000.21x1.26x0.51x1.32x0.74x
52-Week HighHighest price in past year$609.35$26.18$82.22$247.05$495.55
52-Week LowLowest price in past year$272.12$7.53$47.50$134.65$245.96
% of 52W HighCurrent price vs 52-week peak+92.7%+75.3%+78.0%+72.3%+59.5%
RSI (14)Momentum oscillator 0–10050.647.447.760.339.9
Avg Volume (50D)Average daily shares traded508K252K1.4M1.5M1.1M
UTHR leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

IQV leads this category, winning 1 of 1 comparable metric.

Analyst consensus: UTHR as "Buy", DBVT as "Buy", HALO as "Buy", IQV as "Buy", ALNY as "Buy". Consensus price targets imply 134.8% upside for DBVT (target: $46) vs 11.2% for UTHR (target: $628).

MetricUTHR logoUTHRUnited Therapeuti…DBVT logoDBVTDBV Technologies …HALO logoHALOHalozyme Therapeu…IQV logoIQVIQVIA Holdings In…ALNY logoALNYAlnylam Pharmaceu…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$628.00$46.33$75.60$223.75$445.67
# AnalystsCovering analysts3015274452
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises102
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap+4.2%0.0%+4.5%+4.1%0.0%
IQV leads this category, winning 1 of 1 comparable metric.
Key Takeaway

UTHR leads in 3 of 6 categories (Profitability & Efficiency, Total Returns). HALO leads in 1 (Valuation Metrics). 1 tied.

Best OverallUnited Therapeutics Corpora… (UTHR)Leads 3 of 6 categories
Loading custom metrics...

UTHR vs DBVT vs HALO vs IQV vs ALNY: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is UTHR or DBVT or HALO or IQV or ALNY a better buy right now?

For growth investors, Alnylam Pharmaceuticals, Inc.

(ALNY) is the stronger pick with 65. 2% revenue growth year-over-year, versus 5. 9% for IQVIA Holdings Inc. (IQV). United Therapeutics Corporation (UTHR) offers the better valuation at 20. 3x trailing P/E (19. 9x forward), making it the more compelling value choice. Analysts rate United Therapeutics Corporation (UTHR) a "Buy" — based on 30 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — UTHR or DBVT or HALO or IQV or ALNY?

On trailing P/E, United Therapeutics Corporation (UTHR) is the cheapest at 20.

3x versus Alnylam Pharmaceuticals, Inc. at 126. 6x. On forward P/E, Halozyme Therapeutics, Inc. is actually cheaper at 8. 0x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: IQVIA Holdings Inc. wins at 0. 34x versus United Therapeutics Corporation's 1. 03x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — UTHR or DBVT or HALO or IQV or ALNY?

Over the past 5 years, United Therapeutics Corporation (UTHR) delivered a total return of +197.

5%, compared to -68. 3% for DBV Technologies S. A. (DBVT). Over 10 years, the gap is even starker: HALO returned +559. 7% versus DBVT's -87. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — UTHR or DBVT or HALO or IQV or ALNY?

By beta (market sensitivity over 5 years), United Therapeutics Corporation (UTHR) is the lower-risk stock at 0.

21β versus IQVIA Holdings Inc. 's 1. 32β — meaning IQV is approximately 536% more volatile than UTHR relative to the S&P 500. On balance sheet safety, DBV Technologies S. A. (DBVT) carries a lower debt/equity ratio of 13% versus 2% for IQVIA Holdings Inc. — giving it more financial flexibility in a downturn.

05

Which is growing faster — UTHR or DBVT or HALO or IQV or ALNY?

By revenue growth (latest reported year), Alnylam Pharmaceuticals, Inc.

(ALNY) is pulling ahead at 65. 2% versus 5. 9% for IQVIA Holdings Inc. (IQV). On earnings-per-share growth, the picture is similar: Alnylam Pharmaceuticals, Inc. grew EPS 206. 9% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, ALNY leads at 53. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — UTHR or DBVT or HALO or IQV or ALNY?

United Therapeutics Corporation (UTHR) is the more profitable company, earning 41.

9% net margin versus 0. 0% for DBV Technologies S. A. — meaning it keeps 41. 9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HALO leads at 58. 4% versus 0. 0% for DBVT. At the gross margin level — before operating expenses — UTHR leads at 87. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is UTHR or DBVT or HALO or IQV or ALNY more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, IQVIA Holdings Inc. (IQV) is the more undervalued stock at a PEG of 0. 34x versus United Therapeutics Corporation's 1. 03x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Halozyme Therapeutics, Inc. (HALO) trades at 8. 0x forward P/E versus 39. 9x for Alnylam Pharmaceuticals, Inc. — 32. 0x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for DBVT: 134. 8% to $46. 33.

08

Which pays a better dividend — UTHR or DBVT or HALO or IQV or ALNY?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

09

Is UTHR or DBVT or HALO or IQV or ALNY better for a retirement portfolio?

For long-horizon retirement investors, United Therapeutics Corporation (UTHR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

21), +406. 2% 10Y return). Both have compounded well over 10 years (UTHR: +406. 2%, DBVT: -87. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between UTHR and DBVT and HALO and IQV and ALNY?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

In terms of investment character: UTHR is a mid-cap quality compounder stock; DBVT is a mega-cap quality compounder stock; HALO is a small-cap high-growth stock; IQV is a mid-cap quality compounder stock; ALNY is a mid-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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