Biotechnology
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5 / 10Stock Comparison
UTHR vs DBVT vs HALO vs IQV vs ALNY
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Medical - Diagnostics & Research
Biotechnology
UTHR vs DBVT vs HALO vs IQV vs ALNY — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Medical - Diagnostics & Research | Biotechnology |
| Market Cap | $23.98B | $1690.08T | $7.55B | $30.33B | $39.37B |
| Revenue (TTM) | $3.17B | $0.00 | $1.40B | $16.63B | $4.29B |
| Net Income (TTM) | $1.29B | $-168M | $317M | $1.39B | $577M |
| Gross Margin | 86.6% | — | 81.9% | 26.1% | 80.9% |
| Operating Margin | 45.3% | — | 58.4% | 13.9% | 17.5% |
| Forward P/E | 19.9x | — | 8.0x | 14.0x | 39.9x |
| Total Debt | $0.00 | $22M | $0.00 | $16.17B | $1.28B |
| Cash & Equiv. | $1.56B | $194M | $134M | $1.98B | $1.66B |
UTHR vs DBVT vs HALO vs IQV vs ALNY — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| United Therapeutics… (UTHR) | 100 | 479.0 | +379.0% |
| DBV Technologies S.… (DBVT) | 100 | 40.7 | -59.3% |
| Halozyme Therapeuti… (HALO) | 100 | 264.2 | +164.2% |
| IQVIA Holdings Inc. (IQV) | 100 | 119.5 | +19.5% |
| Alnylam Pharmaceuti… (ALNY) | 100 | 218.1 | +118.1% |
Price return only. Dividends and distributions are not included.
Quick Verdict: UTHR vs DBVT vs HALO vs IQV vs ALNY
Each card shows where this stock fits in a portfolio — not just who wins on paper.
UTHR carries the broadest edge in this set and is the clearest fit for income & stability and sleep-well-at-night.
- Dividend streak 1 yrs, beta 0.21
- Lower volatility, beta 0.21, current ratio 6.60x
- Beta 0.21, current ratio 6.60x
- 40.6% margin vs DBVT's 0.3%
DBVT is the #2 pick in this set and the best alternative if momentum is your priority.
- +100.5% vs HALO's -5.3%
HALO ranks third and is worth considering specifically for long-term compounding.
- 5.6% 10Y total return vs ALNY's 410.4%
- Lower P/E (8.0x vs 39.9x)
IQV is the clearest fit if your priority is valuation efficiency.
- PEG 0.34 vs UTHR's 1.03
ALNY is the clearest fit if your priority is growth exposure.
- Rev growth 65.2%, EPS growth 206.9%, 3Y rev CAGR 53.0%
- 65.2% revenue growth vs DBVT's -100.0%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 65.2% revenue growth vs DBVT's -100.0% | |
| Value | Lower P/E (8.0x vs 39.9x) | |
| Quality / Margins | 40.6% margin vs DBVT's 0.3% | |
| Stability / Safety | Beta 0.21 vs IQV's 1.32 | |
| Dividends | Tie | None of these 5 stocks pay a meaningful dividend |
| Momentum (1Y) | +100.5% vs HALO's -5.3% | |
| Efficiency (ROA) | 17.2% ROA vs DBVT's -89.0% |
UTHR vs DBVT vs HALO vs IQV vs ALNY — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
UTHR vs DBVT vs HALO vs IQV vs ALNY — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
UTHR leads in 3 of 6 categories
HALO leads 1 • IQV leads 1 • DBVT leads 0 • ALNY leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
Evenly matched — UTHR and HALO and ALNY each lead in 2 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
IQV and DBVT operate at a comparable scale, with $16.6B and $0 in trailing revenue. UTHR is the more profitable business, keeping 40.6% of every revenue dollar as net income compared to IQV's 8.3%. On growth, ALNY holds the edge at +96.4% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $3.2B | $0 | $1.4B | $16.6B | $4.3B |
| EBITDAEarnings before interest/tax | $1.5B | -$112M | $945M | $3.5B | $677M |
| Net IncomeAfter-tax profit | $1.3B | -$168M | $317M | $1.4B | $577M |
| Free Cash FlowCash after capex | $1.0B | -$151M | $645M | $2.7B | $641M |
| Gross MarginGross profit ÷ Revenue | +86.6% | — | +81.9% | +26.1% | +80.9% |
| Operating MarginEBIT ÷ Revenue | +45.3% | — | +58.4% | +13.9% | +17.5% |
| Net MarginNet income ÷ Revenue | +40.6% | — | +22.7% | +8.3% | +13.5% |
| FCF MarginFCF ÷ Revenue | +32.1% | — | +46.2% | +16.1% | +15.0% |
| Rev. Growth (YoY)Latest quarter vs prior year | -1.6% | — | +51.6% | +8.4% | +96.4% |
| EPS Growth (YoY)Latest quarter vs prior year | -12.2% | +91.5% | -2.1% | +15.0% | +4.4% |
Valuation Metrics
HALO leads this category, winning 3 of 7 comparable metrics.
Valuation Metrics
At 20.3x trailing earnings, UTHR trades at a 84% valuation discount to ALNY's 126.6x P/E. Adjusting for growth (PEG ratio), IQV offers better value at 0.56x vs HALO's 1.09x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $24.0B | $1690.08T | $7.6B | $30.3B | $39.4B |
| Enterprise ValueMkt cap + debt − cash | $22.4B | $1690.08T | $7.4B | $44.5B | $39.0B |
| Trailing P/EPrice ÷ TTM EPS | 20.28x | -0.75x | 25.05x | 22.79x | 126.63x |
| Forward P/EPrice ÷ next-FY EPS est. | 19.89x | — | 7.96x | 13.96x | 39.92x |
| PEG RatioP/E ÷ EPS growth rate | 1.05x | — | 1.09x | 0.56x | — |
| EV / EBITDAEnterprise value multiple | 13.99x | — | 8.20x | 12.98x | 69.97x |
| Price / SalesMarket cap ÷ Revenue | 7.53x | — | 5.41x | 1.86x | 10.60x |
| Price / BookPrice ÷ Book value/share | 3.81x | 0.65x | 162.76x | 4.68x | 50.35x |
| Price / FCFMarket cap ÷ FCF | 23.04x | — | 11.72x | 14.79x | 84.59x |
Profitability & Efficiency
UTHR leads this category, winning 5 of 9 comparable metrics.
Profitability & Efficiency
HALO delivers a 6.5% return on equity — every $100 of shareholder capital generates $6 in annual profit, vs $-130 for DBVT. DBVT carries lower financial leverage with a 0.13x debt-to-equity ratio, signaling a more conservative balance sheet compared to IQV's 2.44x. On the Piotroski fundamental quality scale (0–9), UTHR scores 7/9 vs IQV's 4/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | +19.2% | -130.2% | +6.5% | +22.1% | +98.3% |
| ROA (TTM)Return on assets | +17.2% | -89.0% | +12.5% | +4.7% | +11.8% |
| ROICReturn on invested capital | +21.5% | — | +73.4% | +8.7% | +33.4% |
| ROCEReturn on capital employed | +21.8% | -145.7% | +38.2% | +11.0% | +15.3% |
| Piotroski ScoreFundamental quality 0–9 | 7 | 4 | 5 | 4 | 6 |
| Debt / EquityFinancial leverage | — | 0.13x | — | 2.44x | 1.62x |
| Net DebtTotal debt minus cash | -$1.6B | -$172M | -$134M | $14.2B | -$379M |
| Cash & Equiv.Liquid assets | $1.6B | $194M | $134M | $2.0B | $1.7B |
| Total DebtShort + long-term debt | $0 | $22M | $0 | $16.2B | $1.3B |
| Interest CoverageEBIT ÷ Interest expense | 99.37x | -189.82x | 46.08x | 3.10x | 2.02x |
Total Returns (Dividends Reinvested)
UTHR leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in UTHR five years ago would be worth $29,752 today (with dividends reinvested), compared to $3,172 for DBVT. Over the past 12 months, DBVT leads with a +100.5% total return vs HALO's -5.3%. The 3-year compound annual growth rate (CAGR) favors UTHR at 39.0% vs IQV's -2.0% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +13.7% | +3.6% | -8.8% | -20.7% | -26.3% |
| 1-Year ReturnPast 12 months | +83.4% | +100.5% | -5.3% | +16.6% | +14.2% |
| 3-Year ReturnCumulative with dividends | +168.4% | +18.1% | +111.8% | -5.9% | +40.5% |
| 5-Year ReturnCumulative with dividends | +197.5% | -68.3% | +39.1% | -22.8% | +129.4% |
| 10-Year ReturnCumulative with dividends | +406.2% | -87.1% | +559.7% | +166.6% | +410.4% |
| CAGR (3Y)Annualised 3-year return | +39.0% | +5.7% | +28.4% | -2.0% | +12.0% |
Risk & Volatility
UTHR leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
UTHR is the less volatile stock with a 0.21 beta — it tends to amplify market swings less than IQV's 1.32 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. UTHR currently trades 92.7% from its 52-week high vs ALNY's 59.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.21x | 1.26x | 0.51x | 1.32x | 0.74x |
| 52-Week HighHighest price in past year | $609.35 | $26.18 | $82.22 | $247.05 | $495.55 |
| 52-Week LowLowest price in past year | $272.12 | $7.53 | $47.50 | $134.65 | $245.96 |
| % of 52W HighCurrent price vs 52-week peak | +92.7% | +75.3% | +78.0% | +72.3% | +59.5% |
| RSI (14)Momentum oscillator 0–100 | 50.6 | 47.4 | 47.7 | 60.3 | 39.9 |
| Avg Volume (50D)Average daily shares traded | 508K | 252K | 1.4M | 1.5M | 1.1M |
Analyst Outlook
IQV leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: UTHR as "Buy", DBVT as "Buy", HALO as "Buy", IQV as "Buy", ALNY as "Buy". Consensus price targets imply 134.8% upside for DBVT (target: $46) vs 11.2% for UTHR (target: $628).
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $628.00 | $46.33 | $75.60 | $223.75 | $445.67 |
| # AnalystsCovering analysts | 30 | 15 | 27 | 44 | 52 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | — |
| Dividend StreakConsecutive years of raises | 1 | 0 | — | 2 | — |
| Dividend / ShareAnnual DPS | — | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | +4.2% | 0.0% | +4.5% | +4.1% | 0.0% |
UTHR leads in 3 of 6 categories (Profitability & Efficiency, Total Returns). HALO leads in 1 (Valuation Metrics). 1 tied.
UTHR vs DBVT vs HALO vs IQV vs ALNY: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is UTHR or DBVT or HALO or IQV or ALNY a better buy right now?
For growth investors, Alnylam Pharmaceuticals, Inc.
(ALNY) is the stronger pick with 65. 2% revenue growth year-over-year, versus 5. 9% for IQVIA Holdings Inc. (IQV). United Therapeutics Corporation (UTHR) offers the better valuation at 20. 3x trailing P/E (19. 9x forward), making it the more compelling value choice. Analysts rate United Therapeutics Corporation (UTHR) a "Buy" — based on 30 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — UTHR or DBVT or HALO or IQV or ALNY?
On trailing P/E, United Therapeutics Corporation (UTHR) is the cheapest at 20.
3x versus Alnylam Pharmaceuticals, Inc. at 126. 6x. On forward P/E, Halozyme Therapeutics, Inc. is actually cheaper at 8. 0x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: IQVIA Holdings Inc. wins at 0. 34x versus United Therapeutics Corporation's 1. 03x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — UTHR or DBVT or HALO or IQV or ALNY?
Over the past 5 years, United Therapeutics Corporation (UTHR) delivered a total return of +197.
5%, compared to -68. 3% for DBV Technologies S. A. (DBVT). Over 10 years, the gap is even starker: HALO returned +559. 7% versus DBVT's -87. 1%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — UTHR or DBVT or HALO or IQV or ALNY?
By beta (market sensitivity over 5 years), United Therapeutics Corporation (UTHR) is the lower-risk stock at 0.
21β versus IQVIA Holdings Inc. 's 1. 32β — meaning IQV is approximately 536% more volatile than UTHR relative to the S&P 500. On balance sheet safety, DBV Technologies S. A. (DBVT) carries a lower debt/equity ratio of 13% versus 2% for IQVIA Holdings Inc. — giving it more financial flexibility in a downturn.
05Which is growing faster — UTHR or DBVT or HALO or IQV or ALNY?
By revenue growth (latest reported year), Alnylam Pharmaceuticals, Inc.
(ALNY) is pulling ahead at 65. 2% versus 5. 9% for IQVIA Holdings Inc. (IQV). On earnings-per-share growth, the picture is similar: Alnylam Pharmaceuticals, Inc. grew EPS 206. 9% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, ALNY leads at 53. 0% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — UTHR or DBVT or HALO or IQV or ALNY?
United Therapeutics Corporation (UTHR) is the more profitable company, earning 41.
9% net margin versus 0. 0% for DBV Technologies S. A. — meaning it keeps 41. 9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: HALO leads at 58. 4% versus 0. 0% for DBVT. At the gross margin level — before operating expenses — UTHR leads at 87. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is UTHR or DBVT or HALO or IQV or ALNY more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, IQVIA Holdings Inc. (IQV) is the more undervalued stock at a PEG of 0. 34x versus United Therapeutics Corporation's 1. 03x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Halozyme Therapeutics, Inc. (HALO) trades at 8. 0x forward P/E versus 39. 9x for Alnylam Pharmaceuticals, Inc. — 32. 0x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for DBVT: 134. 8% to $46. 33.
08Which pays a better dividend — UTHR or DBVT or HALO or IQV or ALNY?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
09Is UTHR or DBVT or HALO or IQV or ALNY better for a retirement portfolio?
For long-horizon retirement investors, United Therapeutics Corporation (UTHR) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.
21), +406. 2% 10Y return). Both have compounded well over 10 years (UTHR: +406. 2%, DBVT: -87. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between UTHR and DBVT and HALO and IQV and ALNY?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: UTHR is a mid-cap quality compounder stock; DBVT is a mega-cap quality compounder stock; HALO is a small-cap high-growth stock; IQV is a mid-cap quality compounder stock; ALNY is a mid-cap high-growth stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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