Biotechnology
Compare Stocks
5 / 10Stock Comparison
ZLAB vs DBVT vs IMVT vs AGEN vs RCUS
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
Biotechnology
ZLAB vs DBVT vs IMVT vs AGEN vs RCUS — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology | Biotechnology |
| Market Cap | $2.19B | $1712.35T | $5.53B | $132M | $2.50B |
| Revenue (TTM) | $460M | $0.00 | $0.00 | $114M | $236M |
| Net Income (TTM) | $-176M | $-168M | $-464M | $115K | $-369M |
| Gross Margin | 58.5% | — | — | 35.7% | 90.7% |
| Operating Margin | -49.9% | — | — | -17.7% | -168.6% |
| Forward P/E | — | — | — | 1.8x | — |
| Total Debt | $224M | $22M | $98K | $10M | $99M |
| Cash & Equiv. | $680M | $194M | $714M | $3M | $222M |
ZLAB vs DBVT vs IMVT vs AGEN vs RCUS — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | May 20 | May 26 | Return |
|---|---|---|---|
| Zai Lab Limited (ZLAB) | 100 | 26.6 | -73.4% |
| DBV Technologies S.… (DBVT) | 100 | 41.2 | -58.8% |
| Immunovant, Inc. (IMVT) | 100 | 106.1 | +6.1% |
| Agenus Inc. (AGEN) | 100 | 5.0 | -95.0% |
| Arcus Biosciences, … (RCUS) | 100 | 79.1 | -20.9% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ZLAB vs DBVT vs IMVT vs AGEN vs RCUS
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ZLAB carries the broadest edge in this set and is the clearest fit for growth exposure.
- Rev growth 15.3%, EPS growth 38.5%, 3Y rev CAGR 28.9%
- 15.3% revenue growth vs DBVT's -100.0%
- Beta 1.21 vs AGEN's 2.72
DBVT is the clearest fit if your priority is income & stability.
- Dividend streak 0 yrs, beta 1.26
IMVT is the #2 pick in this set and the best alternative if long-term compounding and sleep-well-at-night is your priority.
- 173.6% 10Y total return vs RCUS's 45.9%
- Lower volatility, beta 1.37, Low D/E 0.0%, current ratio 11.16x
- Beta 1.37, current ratio 11.16x
- 3.2% margin vs RCUS's -156.4%
AGEN ranks third and is worth considering specifically for efficiency.
- 0.1% ROA vs DBVT's -89.0%
RCUS is the clearest fit if your priority is momentum.
- +209.6% vs ZLAB's -30.3%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 15.3% revenue growth vs DBVT's -100.0% | |
| Quality / Margins | 3.2% margin vs RCUS's -156.4% | |
| Stability / Safety | Beta 1.21 vs AGEN's 2.72 | |
| Dividends | Tie | None of these 5 stocks pay a meaningful dividend |
| Momentum (1Y) | +209.6% vs ZLAB's -30.3% | |
| Efficiency (ROA) | 0.1% ROA vs DBVT's -89.0% |
ZLAB vs DBVT vs IMVT vs AGEN vs RCUS — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
ZLAB vs DBVT vs IMVT vs AGEN vs RCUS — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
AGEN leads in 3 of 6 categories
IMVT leads 1 • ZLAB leads 0 • DBVT leads 0 • RCUS leads 0 • 2 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
AGEN leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
ZLAB and IMVT operate at a comparable scale, with $460M and $0 in trailing revenue. AGEN is the more profitable business, keeping 0.1% of every revenue dollar as net income compared to RCUS's -156.4%. On growth, AGEN holds the edge at +27.5% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $460M | $0 | $0 | $114M | $236M |
| EBITDAEarnings before interest/tax | -$214M | -$112M | -$487M | -$10M | -$391M |
| Net IncomeAfter-tax profit | -$176M | -$168M | -$464M | $115,000 | -$369M |
| Free Cash FlowCash after capex | -$159M | -$151M | -$423M | -$159M | -$489M |
| Gross MarginGross profit ÷ Revenue | +58.5% | — | — | +35.7% | +90.7% |
| Operating MarginEBIT ÷ Revenue | -49.9% | — | — | -17.7% | -168.6% |
| Net MarginNet income ÷ Revenue | -38.1% | — | — | +0.1% | -156.4% |
| FCF MarginFCF ÷ Revenue | -34.5% | — | — | -139.1% | -2.1% |
| Rev. Growth (YoY)Latest quarter vs prior year | +17.0% | — | — | +27.5% | -39.3% |
| EPS Growth (YoY)Latest quarter vs prior year | +42.5% | +91.5% | +19.7% | +85.3% | +10.5% |
Valuation Metrics
AGEN leads this category, winning 2 of 3 comparable metrics.
Valuation Metrics
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $2.2B | $1712.35T | $5.5B | $132M | $2.5B |
| Enterprise ValueMkt cap + debt − cash | $1.7B | $1712.35T | $4.8B | $140M | $2.4B |
| Trailing P/EPrice ÷ TTM EPS | -12.35x | -0.76x | -9.97x | -1102.94x | -7.54x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | — | 1.79x | — |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | — | — |
| EV / EBITDAEnterprise value multiple | — | — | — | — | — |
| Price / SalesMarket cap ÷ Revenue | 4.75x | — | — | 1.16x | 10.11x |
| Price / BookPrice ÷ Book value/share | 3.03x | 0.66x | 5.83x | — | 4.22x |
| Price / FCFMarket cap ÷ FCF | — | — | — | — | — |
Profitability & Efficiency
Evenly matched — ZLAB and IMVT and AGEN each lead in 3 of 9 comparable metrics.
Profitability & Efficiency
ZLAB delivers a -22.8% return on equity — every $100 of shareholder capital generates $-23 in annual profit, vs $-130 for DBVT. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to ZLAB's 0.31x. On the Piotroski fundamental quality scale (0–9), AGEN scores 6/9 vs RCUS's 0/9, reflecting solid financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -22.8% | -130.2% | -47.1% | — | -69.0% |
| ROA (TTM)Return on assets | -15.0% | -89.0% | -44.1% | +0.1% | -35.3% |
| ROICReturn on invested capital | -42.8% | — | — | — | -64.1% |
| ROCEReturn on capital employed | -27.9% | -145.7% | -66.1% | — | -42.1% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 4 | 2 | 6 | 0 |
| Debt / EquityFinancial leverage | 0.31x | 0.13x | 0.00x | — | 0.16x |
| Net DebtTotal debt minus cash | -$455M | -$172M | -$714M | $7M | -$123M |
| Cash & Equiv.Liquid assets | $680M | $194M | $714M | $3M | $222M |
| Total DebtShort + long-term debt | $224M | $22M | $98,000 | $10M | $99M |
| Interest CoverageEBIT ÷ Interest expense | -33.25x | -189.82x | — | 1.11x | -13.38x |
Total Returns (Dividends Reinvested)
IMVT leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in IMVT five years ago would be worth $16,241 today (with dividends reinvested), compared to $611 for AGEN. Over the past 12 months, RCUS leads with a +209.6% total return vs ZLAB's -30.3%. The 3-year compound annual growth rate (CAGR) favors IMVT at 12.1% vs AGEN's -51.0% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +14.1% | +4.9% | +5.1% | +16.1% | +6.5% |
| 1-Year ReturnPast 12 months | -30.3% | +110.4% | +96.1% | +27.1% | +209.6% |
| 3-Year ReturnCumulative with dividends | -46.6% | +19.7% | +40.9% | -88.2% | +24.9% |
| 5-Year ReturnCumulative with dividends | -87.5% | -69.1% | +62.4% | -93.9% | -18.6% |
| 10-Year ReturnCumulative with dividends | -29.2% | -87.0% | +173.6% | -94.3% | +45.9% |
| CAGR (3Y)Annualised 3-year return | -18.9% | +6.2% | +12.1% | -51.0% | +7.7% |
Risk & Volatility
Evenly matched — ZLAB and IMVT each lead in 1 of 2 comparable metrics.
Risk & Volatility
ZLAB is the less volatile stock with a 1.21 beta — it tends to amplify market swings less than AGEN's 2.72 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 90.5% from its 52-week high vs ZLAB's 44.6% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.21x | 1.26x | 1.37x | 2.72x | 1.95x |
| 52-Week HighHighest price in past year | $44.34 | $26.18 | $30.09 | $7.34 | $28.72 |
| 52-Week LowLowest price in past year | $15.96 | $7.53 | $13.36 | $2.71 | $7.06 |
| % of 52W HighCurrent price vs 52-week peak | +44.6% | +76.3% | +90.5% | +51.1% | +86.3% |
| RSI (14)Momentum oscillator 0–100 | 47.7 | 48.1 | 60.2 | 48.8 | 60.5 |
| Avg Volume (50D)Average daily shares traded | 729K | 252K | 1.4M | 814K | 1.2M |
Analyst Outlook
AGEN leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: ZLAB as "Buy", DBVT as "Buy", IMVT as "Buy", AGEN as "Buy", RCUS as "Buy". Consensus price targets imply 131.8% upside for DBVT (target: $46) vs 21.0% for RCUS (target: $30).
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $35.00 | $46.33 | $45.50 | $7.33 | $30.00 |
| # AnalystsCovering analysts | 11 | 15 | 23 | 11 | 18 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | — |
| Dividend StreakConsecutive years of raises | — | 0 | — | 1 | — |
| Dividend / ShareAnnual DPS | — | — | — | — | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | +0.1% | 0.0% |
AGEN leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). IMVT leads in 1 (Total Returns). 2 tied.
ZLAB vs DBVT vs IMVT vs AGEN vs RCUS: Key Questions Answered
9 questions · data-driven answers · updated daily
01Is ZLAB or DBVT or IMVT or AGEN or RCUS a better buy right now?
For growth investors, Zai Lab Limited (ZLAB) is the stronger pick with 15.
3% revenue growth year-over-year, versus -4. 3% for Arcus Biosciences, Inc. (RCUS). Analysts rate Zai Lab Limited (ZLAB) a "Buy" — based on 11 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which is the better long-term investment — ZLAB or DBVT or IMVT or AGEN or RCUS?
Over the past 5 years, Immunovant, Inc.
(IMVT) delivered a total return of +62. 4%, compared to -93. 9% for Agenus Inc. (AGEN). Over 10 years, the gap is even starker: IMVT returned +173. 6% versus AGEN's -94. 3%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
03Which is safer — ZLAB or DBVT or IMVT or AGEN or RCUS?
By beta (market sensitivity over 5 years), Zai Lab Limited (ZLAB) is the lower-risk stock at 1.
21β versus Agenus Inc. 's 2. 72β — meaning AGEN is approximately 125% more volatile than ZLAB relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 31% for Zai Lab Limited — giving it more financial flexibility in a downturn.
04Which is growing faster — ZLAB or DBVT or IMVT or AGEN or RCUS?
By revenue growth (latest reported year), Zai Lab Limited (ZLAB) is pulling ahead at 15.
3% versus -4. 3% for Arcus Biosciences, Inc. (RCUS). On earnings-per-share growth, the picture is similar: Agenus Inc. grew EPS 100. 0% year-over-year, compared to -347. 5% for DBV Technologies S. A.. Over a 3-year CAGR, RCUS leads at 30. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
05Which has better profit margins — ZLAB or DBVT or IMVT or AGEN or RCUS?
Agenus Inc.
(AGEN) is the more profitable company, earning 0. 1% net margin versus -142. 9% for Arcus Biosciences, Inc. — meaning it keeps 0. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: DBVT leads at 0. 0% versus -156. 3% for RCUS. At the gross margin level — before operating expenses — RCUS leads at 96. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
06Is ZLAB or DBVT or IMVT or AGEN or RCUS more undervalued right now?
Analyst consensus price targets imply the most upside for DBVT: 131.
8% to $46. 33.
07Which pays a better dividend — ZLAB or DBVT or IMVT or AGEN or RCUS?
None of the stocks in this comparison currently pay a material dividend.
All are effectively zero-yield and should be held for capital appreciation rather than income.
08Is ZLAB or DBVT or IMVT or AGEN or RCUS better for a retirement portfolio?
For long-horizon retirement investors, Zai Lab Limited (ZLAB) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1.
21)). Agenus Inc. (AGEN) carries a higher beta of 2. 72 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (ZLAB: -29. 2%, AGEN: -94. 3%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
09What are the main differences between ZLAB and DBVT and IMVT and AGEN and RCUS?
Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.
In terms of investment character: ZLAB is a small-cap high-growth stock; DBVT is a mega-cap quality compounder stock; IMVT is a small-cap quality compounder stock; AGEN is a small-cap quality compounder stock; RCUS is a small-cap quality compounder stock. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
Find Stocks Like These
Explore pre-built screens for each stock's profile, or build a custom screen to find stocks that outperform all of them.
You Might Also Compare
Based on how these companies actually compete and overlap — not just which sector they're filed under.