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ASMBAssembly Biosciences, Inc.
$25.15$400M
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ASMB logoAssembly Biosciences, Inc.(ASMB)Earnings, Financials & Key Ratios

ASMB•NASDAQ
Price updated Jun 19, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryVaccines and Infectious Disease
AboutAssembly Biosciences, Inc., a clinical-stage biotechnology company, discovers and develops therapeutic candidates for the treatment of hepatitis B virus (HBV) infection in the United States. The company's lead product candidate is Vebicorvir, which as completed Phase 2 clinical trials to treat patients with chronic HBV infection. It is also developing ABI-H3733 that has completed Phase 1a clinical study, and ABI-4334, which is in pre-clinical trials for the treatment of HBV. The company has collaboration agreements with BeiGene, Ltd. and Arbutus Biopharma Corporation; and Antios Therapeutics, Inc. to evaluate a triple combination treatment in patients with chronic hepatitis B virus infection. It also has strategic license agreements with Indiana University Research and Technology Corporation; and Door Pharmaceuticals, LLC. The company was formerly known as Ventrus Biosciences, Inc. and changed its name to Assembly Biosciences, Inc. in June 2014. Assembly Biosciences, Inc. was incorporated in 2005 and is headquartered in South San Francisco, California.Show more
  • Revenue$72M+153.5%
  • EBITDA-$12M+73.5%
  • Net Income-$6M+84.8%
  • EPS (Diluted)-0.55+91.8%
  • Gross Margin99.82%-0.2%
  • EBITDA Margin-16.58%+89.6%
  • Operating Margin-16.76%+89.5%
  • Net Margin-8.47%+94.0%
  • ROE-5.1%+95.3%

ASMB Key Insights

Assembly Biosciences, Inc. (ASMB) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Company is almost debt free
  • ✓Strong 5Y profit CAGR of 37.1%
  • ✓High quality earnings: Operating CF exceeds net income
  • ✓Trading at only 1.3x book value

✗Weaknesses

  • ✗Negative free cash flow
  • ✗Shares diluted 86.7% in last year
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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ASMB Price & Volume

Assembly Biosciences, Inc. (ASMB) stock price & volume — 10-year historical chart

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ASMB Growth Metrics

Assembly Biosciences, Inc. (ASMB) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-1.78%
3 Years-
TTM121.11%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM84.01%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM90.91%

Return on Capital

10 Years-45.35%
5 Years-53.29%
3 Years-44.34%
Last Year-8.65%

ASMB Recent Earnings

Assembly Biosciences, Inc. (ASMB) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 8/12 qtrs (67%)●Beat Revenue 6/12 qtrs (75%)
Q2 2026Latest
May 7, 2026
Metric
Actual
Est
EPS
$0.54+26.0%
$0.73
Rev
$8M-11.4%
$9M
Q2 2026
Mar 19, 2026
Metric
Actual
Est
EPS
$2.48+586.3%
$0.51
Rev
$42M+472.2%
$7M
Q4 2025
Nov 10, 2025
Metric
Actual
Est
EPS
$0.72-44.0%
$0.50
Rev
$11M+44.6%
$7M
Q3 2025
Aug 6, 2025
Metric
Actual
Est
EPS
$1.33-103.6%
$0.65
Rev
$10M+3.2%
$9M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 7, 2026
$0.54vs $0.73+26.0%
$8Mvs $9M-11.4%
Q2 2026Mar 19, 2026
$2.48vs $0.51+586.3%
$42Mvs $7M+472.2%
Q4 2025Nov 10, 2025
$0.72vs $0.50-44.0%
$11Mvs $7M+44.6%
Q3 2025Aug 6, 2025
$1.33vs $0.65-103.6%
$10Mvs $9M+3.2%
Based on last 12 quarters of dataView full earnings history →

ASMB Peer Comparison

Assembly Biosciences, Inc. (ASMB) competitors in Vaccines and Infectious Disease — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
ARWR logoARWRArrowhead Pharmaceuticals, Inc.Direct Competitor11.52B81.82-6706.56232.58%-48.38%-55.09%0.73
RCKT logoRCKTRocket Pharmaceuticals, Inc.Direct Competitor365.8M3.35-1.67-70.79%0.09
REPL logoREPLReplimune Group, Inc.Direct Competitor841.41M10.19-3.32-102.69%0.18
GILD logoGILDGilead Sciences, Inc.Product Competitor153.66B123.7618.252.39%30.99%42.33%1.09
REGN logoREGNRegeneron Pharmaceuticals, Inc.Product Competitor63.37B609.9414.700.99%29.65%14.32%0.09
ALNY logoALNYAlnylam Pharmaceuticals, Inc.Product Competitor37.1B278.09119.3565.19%13.46%98.29%1.62
VRTX logoVRTXVertex Pharmaceuticals IncorporatedProduct Competitor114.88B451.6329.489.57%35.4%23.93%0.21
INCY logoINCYIncyte CorporationProduct Competitor19.62B98.2215.3221.22%26.71%29.31%0.01

Compare ASMB vs Peers

Assembly Biosciences, Inc. (ASMB) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ARWR

Most directly comparable listed peer for ASMB.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare ASMB against a more recognizable public peer.

Peer Set

Compare Top 5

vs ARWR, RCKT, REPL, GILD

ASMB Income Statement

Assembly Biosciences, Inc. (ASMB) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
9.02M14.8M15.96M79.11M6.25M07.16M28.52M72.3M71.1M
Revenue Growth %
-64.15%7.83%395.55%-92.09%-100%-298.16%153.52%121.11%
Cost of Goods Sold
44.23M72.74M85.32M101.34M069.08M48.9M0129K16.18M
COGS % of Revenue
490.37%491.36%534.51%128.1%--682.67%-0.18%-
Gross Profit
-35.21M▲ 0%
-57.94M▼ 64.6%
-69.36M▼ 19.7%
-22.23M▲ 67.9%
6.25M▲ 128.1%
-69.08M▼ 1204.6%
-41.74M▲ 39.6%
28.52M▲ 168.3%
72.17M▲ 153.1%
54.91M▲ 0%
Gross Margin %
-390.37%-391.36%-434.51%-28.1%100%--582.67%100%99.82%77.24%
Gross Profit Growth %
-43770.17%-64.56%-19.72%67.95%128.13%-1204.57%39.58%168.33%153.06%-
Operating Expenses
61.25M107.54M33.35M42.54M138.94M25.03M22.91M73.94M84.42M68.52M
OpEx % of Revenue
679.09%726.42%208.93%53.78%2221.65%-319.82%259.26%116.76%-
Selling, General & Admin
17.02M34.8M34.86M36.86M28.78M23.93M22.91M18.01M19.61M19.78M
SG&A % of Revenue
188.72%235.06%218.37%46.6%460.19%-319.82%63.14%27.12%-
Research & Development
44.23M72.74M85.76M106.82M68.52M69.98M48.9M55.93M64.81M64.86M
R&D % of Revenue
490.37%491.36%537.22%135.04%1095.68%-682.67%196.12%89.64%-
Other Operating Expenses
00-87.26M-101.14M41.64M-68.88M-48.9M00-1000K
Operating Income
-52.23M▲ 0%
-92.73M▼ 77.6%
-102.71M▼ 10.8%
-64.78M▲ 36.9%
-132.69M▼ 104.8%
-94.11M▲ 29.1%
-64.65M▲ 31.3%
-45.42M▲ 29.7%
-12.12M▲ 73.3%
-13.55M▲ 0%
Operating Margin %
-579.09%-626.42%-643.44%-81.89%-2121.65%--902.5%-159.26%-16.76%-19.05%
Operating Income Growth %
-15.35%-77.56%-10.76%36.94%-104.84%29.07%31.31%29.74%73.32%-
EBITDA
-52.01M-92.09M-102.22M-64.08M-132.22M-93.62M-64.2M-45.29M-11.99M-13.43M
EBITDA Margin %
-576.66%-622.08%-640.35%-81.01%-2114.2%--896.22%-158.8%-16.58%-18.88%
EBITDA Growth %
-15.07%-77.07%-11%37.31%-106.32%29.2%31.43%29.45%73.53%69.83%
D&A (Non-Cash Add-back)
219.22K643K494K691K466K498K450K129K129K122K
EBIT
-52.23M-92.73M-104.22M-59.09M-91.05M-93.01M-64.65M-45.42M-12.12M-11.86M
Net Interest Income
983K3.08M4.3M2.62M302K1.02M3.45M5.57M6M7.16M
Interest Income
983.21K3.08M4.3M2.62M302K1.02M3.45M5.57M6M7.16M
Interest Expense
0000000000
Other Income/Expense
368.2K3.08M5.85M2.62M302K1.02M3.45M5.57M6M7.16M
Pretax Income
-51.86M▲ 0%
-89.65M▼ 72.9%
-96.86M▼ 8.0%
-62.15M▲ 35.8%
-132.39M▼ 113.0%
-93.09M▲ 29.7%
-61.2M▲ 34.3%
-39.85M▲ 34.9%
-6.12M▲ 84.6%
-6.38M▲ 0%
Pretax Margin %
-575.01%-605.59%-606.78%-78.57%-2116.82%--854.32%-139.72%-8.47%-8.98%
Income Tax
-9.05M1.1M774K0-2.53M033K330K00
Effective Tax Rate %
17.45%-1.23%-0.8%0%1.91%0%-0.05%-0.83%0%0%
Net Income
-42.81M▲ 0%
-90.75M▼ 112.0%
-97.63M▼ 7.6%
-62.15M▲ 36.3%
-129.85M▼ 108.9%
-93.09M▲ 28.3%
-61.23M▲ 34.2%
-40.18M▲ 34.4%
-6.12M▲ 84.8%
-6.38M▲ 0%
Net Margin %
-474.66%-613.02%-611.63%-78.57%-2076.35%--854.78%-140.87%-8.47%-8.98%
Net Income Growth %
3.28%-111.99%-7.58%36.34%-108.93%28.31%34.23%34.38%84.76%84.01%
Net Income (Continuing)
-42.81M-90.75M-97.63M-62.15M-129.85M-93.09M-61.23M-40.18M-6.12M-6.38M
Discontinued Operations
0000000000
Minority Interest
0000000000
EPS (Diluted)
-24.10▲ 0%
-39.80▼ 65.1%
-27.80▲ 30.2%
-15.00▲ 46.0%
-36.00▼ 140.0%
-22.82▲ 36.6%
-13.38▲ 41.4%
-6.69▲ 50.0%
-0.55▲ 91.8%
-0.38▲ 0%
EPS Growth %
6.23%-65.15%30.15%46.04%-140%36.61%41.37%50%91.78%90.91%
EPS (Basic)
-24.10-39.80-27.80-15.00-36.00-22.82-13.38-6.69-0.55-
Diluted Shares Outstanding
1.78M2.28M3.51M3.97M3.61M4.03M4.58M6M11.21M16.9M
Basic Shares Outstanding
1.78M2.28M3.51M3.97M3.61M4.03M4.58M6M11.21M16.9M
Dividend Payout Ratio
----------

ASMB Balance Sheet

Assembly Biosciences, Inc. (ASMB) balance sheet — assets, liabilities & shareholders' equity

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
123.12M222.5M282.78M224.49M154.2M96.97M133.79M115.5M254.55M232.61M
Cash & Short-Term Investments
119.95M218.08M274.04M216.41M146.63M91.61M130.25M112.08M248.11M226.6M
Cash Only
82.03M41.47M46.73M59.44M45.63M52.42M19.84M38.34M58.45M31.12M
Short-Term Investments
37.91M176.61M227.31M156.97M101M39.19M110.41M73.73M189.66M195.48M
Accounts Receivable
2.27M2.43M3.37M1.23M336K944K43K400K974K451K
Days Sales Outstanding
92.0359.9177.155.6819.61-2.195.124.923
Inventory
000000-3.2M000
Days Inventory Outstanding
----------
Other Current Assets
01.99M5.36M00300K3.5M3.02M5.47M5.56M
Total Non-Current Assets
46.18M45.54M65.11M58.76M36.86M4.83M3.04M3.67M3.04M2.9M
Property, Plant & Equipment
860.03K557K13.8M10.73M7.18M3.94M2.72M3.35M2.73M2.58M
Fixed Asset Turnover
10.49x26.58x1.16x7.37x0.87x-2.63x8.51x26.49x25.42x
Goodwill
12.64M12.64M12.64M12.64M000000
Intangible Assets
29M29M29M29M000000
Long-Term Investments
3.35M00027.97M00000
Other Non-Current Assets
339.56K3.35M1.68M6.39M1.7M889K312K312K312K312K
Total Assets
169.3M▲ 0%
268.05M▲ 58.3%
347.89M▲ 29.8%
283.25M▼ 18.6%
191.06M▼ 32.5%
101.79M▼ 46.7%
136.82M▲ 34.4%
119.17M▼ 12.9%
257.59M▲ 116.2%
235.51M▲ 0%
Asset Turnover
0.05x0.06x0.05x0.28x0.03x-0.05x0.24x0.28x0.35x
Asset Growth %
72.55%58.32%29.79%-18.58%-32.55%-46.72%34.41%-12.9%116.16%363.42%
Total Current Liabilities
13.49M18.47M24.44M24.43M16.07M16.3M39.23M47.8M48.78M35M
Accounts Payable
2.12M3.69M1.73M4.6M2.66M2.49M461K585K1.17M1.13M
Days Payables Outstanding
17.5318.537.416.56-13.173.44-3.31K26.65
Short-Term Debt
003.19M00000569K590K
Deferred Revenue (Current)
5.23M5.1M6.41M00030.91M37.62M36.9M65.98M
Other Current Liabilities
6.85M4.67M7.8M7.02M6.43M599K1.15M9.13M10.14M4.2M
Current Ratio
9.13x12.05x11.57x9.19x9.59x5.95x3.41x2.42x5.22x6.65x
Quick Ratio
9.13x12.05x11.57x9.19x9.59x5.95x3.49x2.42x5.22x6.65x
Cash Conversion Cycle
----------23.65
Total Non-Current Liabilities
42.69M38.92M50.23M18.24M6.06M2.83M56.5M38.01M2.06M1.9M
Long-Term Debt
0000000001.9M
Capital Lease Obligations
009.08M6.72M3.33M101K1.12M2.63M2.06M6.62M
Deferred Tax Liabilities
2.14M3.25M10.51M2.53M000000
Other Non-Current Liabilities
0108K0002.73M035.38M00
Total Liabilities
56.18M57.39M74.67M42.68M22.13M19.13M95.73M85.81M50.84M36.9M
Total Debt
0012.27M10.13M6.48M3.46M2.34M3.09M2.63M2.49M
Net Debt
-82.03M-41.47M-34.46M-49.31M-39.15M-48.95M-17.5M-35.26M-55.82M-28.63M
Debt / Equity
--0.04x0.04x0.04x0.04x0.06x0.09x0.01x0.01x
Debt / EBITDA
----------0.19x
Net Debt / EBITDA
---------2.13x
Interest Coverage
----------
Total Equity
113.12M▲ 0%
210.65M▲ 86.2%
273.22M▲ 29.7%
240.58M▼ 11.9%
168.93M▼ 29.8%
82.66M▼ 51.1%
41.1M▼ 50.3%
33.36M▼ 18.8%
206.75M▲ 519.8%
198.61M▲ 0%
Equity Growth %
41.62%86.22%29.7%-11.95%-29.78%-51.07%-50.28%-18.83%519.78%1706.54%
Book Value per Share
63.7392.3977.8860.6346.8420.498.985.5618.4411.75
Total Shareholders' Equity
113.12M210.65M273.22M240.58M168.93M82.66M41.1M33.36M206.75M198.61M
Common Stock
20.14K25K32K34K48K4K5K7K16K16K
Retained Earnings
-251.04M-341.79M-439.42M-501.57M-631.43M-724.52M-785.75M-825.92M-832.05M-841.13M
Treasury Stock
0000000000
Accumulated OCI
-392.39K-347K-201K-270K-419K-803K-81K-211K-41K-368K
Minority Interest
0000000000

ASMB Cash Flow Statement

Assembly Biosciences, Inc. (ASMB) cash flow — operating, investing & free cash flow history

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
1.86M-64.96M-84.07M-62.96M-93.4M-84.46M22.74M-51.12M-41.09M-39.75M
Operating CF Margin %
20.62%-438.79%-526.64%-79.59%-1493.38%-317.51%-179.23%-56.83%-
Operating CF Growth %
105.33%-3592.21%-29.42%25.11%-48.35%9.56%126.93%-324.76%19.61%3606.5%
Net Income
-42.81M-90.75M-97.63M-62.15M-129.85M-93.09M-61.23M-40.18M-6.12M-6.38M
Depreciation & Amortization
219.22K643K494K691K466K498K450K129K129K96K
Stock-Based Compensation
8.6M28.48M20.56M21.85M5.24M6.59M5.12M3.12M4.68M3.96M
Deferred Taxes
-9.05M1.1M-774K0-2.53M00000
Other Non-Cash Items
615.13K-229K2.82M6.96M44.69M3.66M2.06M-2.24M-1.5M-652K
Working Capital Changes
44.28M-4.21M-9.53M-30.31M-11.4M-2.12M76.34M-11.95M-38.28M-36.78M
Change in Receivables
-2.27M-156K-944K2.14M894K-608K901K43K-974K-451K
Change in Inventory
1.1M-601K-3.01M0000000
Change in Payables
-244.19K1.57M-1.96M2.87M-1.94M-166K-2.03M124K586K254K
Cash from Investing
-15.64M-135.4M-50.32M68.07M26.52M90.64M-69.14M40.17M-113.47M-125.44M
Capital Expenditures
-864.56K-340K-1.55M-470K-3.1M-102K-255K-28K-66K-85K
CapEx % of Revenue
9.59%2.3%9.74%0.59%49.5%-3.56%0.1%0.09%0.12%
Acquisitions
-33.18B-48.88M-1.74M01.5M1.5M0000
Investments
----------
Other Investing
33.18B48.88M1.74M-1.75M857K024K02.35M1.21M
Cash from Financing
67.24M159.79M139.65M7.6M53.06M614K13.82M29.45M174.67M172.89M
Debt Issued (Net)
0000000000
Equity Issued (Net)
67.24M155.43M134.66M5.45M52.81M325K13.69M29.29M174.67M172.89M
Dividends Paid
0000000000
Share Repurchases
0000000000
Other Financing
04.37M4.99M2.15M258K289K129K155K00
Net Change in Cash
53.46M▲ 0%
-40.56M▼ 175.9%
5.26M▲ 113.0%
12.71M▲ 141.6%
-13.82M▼ 208.7%
6.79M▲ 149.1%
-32.58M▼ 579.7%
18.5M▲ 156.8%
20.11M▲ 8.7%
7.71M▲ 0%
Free Cash Flow
995.52K▲ 0%
-65.3M▼ 6659.2%
-85.62M▼ 31.1%
-65.18M▲ 23.9%
-96.49M▼ 48.0%
-84.56M▲ 12.4%
22.49M▲ 126.6%
-51.15M▼ 327.4%
-41.16M▲ 19.5%
-39.84M▲ 0%
FCF Margin %
11.04%-441.08%-536.37%-82.39%-1542.88%-313.95%-179.33%-56.93%-56.03%
FCF Growth %
102.84%-6659.2%-31.12%23.88%-48.05%12.36%126.59%-327.43%19.52%29.13%
FCF per Share
0.56-28.64-24.41-16.43-26.75-20.964.91-8.52-3.67-2.36
FCF Conversion (FCF/Net Income)
-0.04x0.72x0.86x1.01x0.72x0.91x-0.37x1.27x6.71x6.24x
Interest Paid
0000000000
Taxes Paid
0000000421K00

ASMB Key Ratios

Assembly Biosciences, Inc. (ASMB) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201720182019202020212022202320242025TTM
Return on Equity (ROE)
-44.36%-56.06%-40.36%-24.19%-63.42%-74%-98.95%-107.92%-5.1%-4.21%
Return on Invested Capital (ROIC)
-95.09%-69.46%-37.77%-22.6%-62%-86.35%-169.2%-313.93%-12.2%-8.45%
Gross Margin
-390.37%-391.36%-434.51%-28.1%100%--582.67%100%99.82%77.24%
Net Margin
-474.66%-613.02%-611.63%-78.57%-2076.35%--854.78%-140.87%-8.47%-8.98%
Debt / Equity
--0.04x0.04x0.04x0.04x0.06x0.09x0.01x0.01x
FCF Conversion
-0.04x0.72x0.86x1.01x0.72x0.91x-0.37x1.27x6.71x6.24x
Revenue Growth
-64.15%7.83%395.55%-92.09%-100%-298.16%153.52%121.11%
Related:ASMB Dividend History·ASMB Revenue History·ASMB Price History·ASMB P/E History·ASMB Financial Ratios·ASMB Institutional Holders

ASMB SEC Filings & Documents

Assembly Biosciences, Inc. (ASMB) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 7, 2026·SEC

Material company update

Mar 30, 2026·SEC

Material company update

Mar 19, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 19, 2026·SEC

FY 2025

Mar 20, 2025·SEC

FY 2024

Mar 28, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 7, 2026·SEC

FY 2025

Nov 10, 2025·SEC

FY 2025

Aug 6, 2025·SEC

ASMB Frequently Asked Questions

Assembly Biosciences, Inc. (ASMB) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Assembly Biosciences, Inc. (ASMB) reported $71.1M in revenue for fiscal year 2025.

Assembly Biosciences, Inc. (ASMB) grew revenue by 153.5% over the past year. This is strong growth.

Assembly Biosciences, Inc. (ASMB) reported a net loss of $6.4M for fiscal year 2025.

Dividend & Returns

Assembly Biosciences, Inc. (ASMB) has a return on equity (ROE) of -5.1%. Negative ROE indicates the company is unprofitable.

Assembly Biosciences, Inc. (ASMB) had negative free cash flow of $39.8M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in ASMB back in 2008?

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