The capital structure now carries $269.6 million of total debt against $133.8 million of cash and only $10.6 million of equity (D/E of 25.47x), with debt ballooning roughly 23-fold from $15.1 million in 2025Q2 while total assets contracted 35.8% to $317.0 million.
AnaptysBio, Inc. (ANAB) balance sheet — 13-year assets, liabilities & shareholders' equity history
| Metric | TTM | Dec'25 | Dec'24 | Dec'23 | Dec'22 | Dec'21 | Dec'20 | Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 |
|---|
| Total Current Assets | 198.43M | 350.25M | 431.88M | 406.83M | 447.2M | 553.88M | 396.56M | 377.73M | 434.22M | 252.7M | 58.21M | 53.46M | 24.4M | 3.05M |
| Cash & Short-Term Investments | 164.14M | 311.64M | 385.37M | 390.9M | 441.24M | 548.1M | 393.65M | 374.23M | 427.08M | 248.41M | 51.23M | 51.68M | 22.19M | 2.81M |
| Cash Only | 133.83M | 238.2M | 123.08M | 35.97M | 71.31M | 495.73M | 250.46M | 171.02M | 113.6M | 81.19M | 51.23M | 51.68M | 22.19M | 2.81M |
| Short-Term Investments | 30.32M | 73.44M | 262.29M | 354.94M | 369.93M | 52.37M | 143.2M | 203.21M | 313.49M | 167.22M | 0 | 0 | 0 | 0 |
| Accounts Receivable | 31.63M | 33.85M | 40.77M | 6.85M | 1.42M | 876K | 0 | 0 | 174K | 1.6M | 5.34M | 1.23M | 1.46M | 0 |
| Days Sales Outstanding | 57.88 | 52.66 | 163.01 | 145.75 | 50.35 | 5.06 | - | - | 12.7 | 58.44 | 116.89 | 25.47 | 33.53 | - |
| Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Days Inventory Outstanding | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Other Current Assets | 2.65M | 4.76M | 5.74M | 9.08M | 4.54M | 0 | 0 | 0 | 0 | 0 | 0 | 554K | 758K | 0 |
| Total Non-Current Assets | 118.56M | 14.14M | 51.96M | 45.55M | 163.18M | 89.19M | 19.99M | 57.46M | 74.78M | 76.67M | 3.97M | 2.82M | 664K | 860K |
| Property, Plant & Equipment | 11.66M | 13.89M | 16.23M | 18.27M | 19.99M | 21.84M | 2.13M | 1.62M | 1.45M | 665K | 471K | 551K | 579K | 750K |
| Fixed Asset Turnover | 19.73x | 16.89x | 5.62x | 0.94x | 0.51x | 2.89x | 35.26x | 4.94x | 3.46x | 15.04x | 35.42x | 31.89x | 27.35x | 7.31x |
| Goodwill | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Intangible Assets | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Long-Term Investments | 7.7M | 0 | 35.47M | 27.03M | 142.94M | 67.1M | 17.55M | 54.3M | 73.13M | 75.9M | 60K | 60K | 0 | 0 |
| Other Non-Current Assets | 256K | 256K | 256K | 256K | 256K | 256K | 318K | 1.54M | 208K | 106K | 3.44M | 2.21M | 85K | 110K |
| Total Assets | 316.98M | 364.39M | 483.83M | 452.39M | 610.38M | 643.07M | 416.55M | 435.2M | 509M | 329.36M | 62.18M | 56.28M | 25.07M | 3.91M |
| Asset Turnover | 0.77x | 0.64x | 0.19x | 0.04x | 0.02x | 0.10x | 0.18x | 0.02x | 0.01x | 0.03x | 0.27x | 0.31x | 0.63x | 1.40x |
| Asset Growth % | -80.46% | -24.69% | 6.95% | -25.88% | -5.08% | 54.38% | -4.28% | -14.5% | 54.54% | 429.69% | 10.48% | 124.54% | 540.39% | - |
| Total Current Liabilities | 35.35M | 38.63M | 45.43M | 37.44M | 26.05M | 16.1M | 19.82M | 29.54M | 21.84M | 14.09M | 5.71M | 7.38M | 11.68M | 3.16M |
| Accounts Payable | 4.39M | 3.87M | 4M | 4.7M | 2.78M | 1.74M | 4.22M | 16.24M | 5.44M | 2.32M | 2.28M | 1.52M | 415K | 197K |
| Days Payables Outstanding | -22.43 | 583.13 | 8.92 | 12.96 | 11.44 | 6.45 | 19.23 | 59.66 | 35.35 | 28.8 | 53.92 | 32.08 | 17.58 | 8.15 |
| Short-Term Debt | 0 | 0 | 1.93M | 0 | 0 | 0 | 0 | 1.38M | 7.57M | 6.88M | 0 | 0 | 0 | 818K |
| Deferred Revenue (Current) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8.7M | 4.86M | 3.43M | 2.94M | 10.09M | 1.29M |
| Other Current Liabilities | 28.8M | 11.09M | 31.05M | 23.77M | 5.38M | 4.18M | 3.69M | 2.15M | 2.42M | 1.59M | 973K | 772K | 588K | 485K |
| Current Ratio | 5.61x | 9.07x | 9.51x | 10.87x | 17.16x | 34.40x | 20.01x | 12.79x | 19.89x | 17.93x | 10.20x | 7.25x | 2.09x | 0.97x |
| Quick Ratio | 5.61x | 9.07x | 9.51x | 10.87x | 17.16x | 34.40x | 20.01x | 12.79x | 19.89x | 17.93x | 10.20x | 7.25x | 2.09x | 0.97x |
| Cash Conversion Cycle | 80.31 | - | - | - | - | - | - | - | - | - | - | - | - | - |
| Total Non-Current Liabilities | 300.07M | 288.56M | 367.54M | 326.84M | 322.23M | 270.54M | 0 | 654K | 796K | 7.69M | 17.2M | 6.57M | 7.39M | 607K |
| Long-Term Debt | 256.49M | 12.03M | 353.43M | 0 | 0 | 0 | 0 | 0 | 625K | 7.55M | 13.81M | 4.9M | 4.79M | 0 |
| Capital Lease Obligations | 47.02M | 0 | 14.11M | 16.04M | 17.81M | 19.45M | 0 | 654K | 0 | 0 | 0 | 0 | 0 | 0 |
| Deferred Tax Liabilities | 29.02M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -171K | -140K | -154K | -115K | 0 | 0 |
| Other Non-Current Liabilities | 3.62M | 276.53M | 0 | 310.81M | 304.41M | 251.09M | 0 | 0 | 171K | 140K | 3.4M | 1.66M | 569K | 607K |
| Total Liabilities | 306.4M | 327.19M | 412.97M | 364.29M | 348.28M | 286.64M | 19.82M | 30.19M | 22.63M | 21.78M | 22.91M | 13.94M | 19.07M | 3.77M |
| Total Debt | 269.59M | 14.11M | 369.46M | 17.81M | 19.45M | 20.95M | 342K | 2.9M | 8.26M | 14.45M | 13.81M | 4.92M | 4.92M | 932K |
| Net Debt | 135.76M | -224.08M | 246.38M | -18.15M | -51.86M | -474.77M | -250.11M | -168.12M | -105.34M | -66.74M | -37.42M | -46.76M | -17.27M | -1.88M |
| Debt / Equity | 25.47x | 0.38x | 5.21x | 0.20x | 0.07x | 0.06x | 0.00x | 0.01x | 0.02x | 0.05x | 0.35x | 0.12x | 0.82x | 6.43x |
| Debt / EBITDA | 2.66x | 0.28x | - | - | - | - | - | - | - | - | - | - | 0.95x | - |
| Net Debt / EBITDA | 1.34x | -4.45x | - | - | - | - | - | - | - | - | - | - | -3.33x | - |
| Interest Coverage | 1.07x | 0.84x | -1.90x | -8.69x | -5.10x | -39.86x | - | -92.65x | -36.44x | -15.94x | -8.30x | -10.45x | 3.76x | -5.26x |
| Total Equity | 10.59M | 37.21M | 70.87M | 88.1M | 262.1M | 356.43M | 396.73M | 405.01M | 486.37M | 307.58M | 39.27M | 42.34M | 5.99M | 145K |
| Equity Growth % | -121.23% | -47.49% | -19.56% | -66.39% | -26.46% | -10.16% | -2.04% | -16.73% | 58.13% | 683.29% | -7.25% | 606.44% | 4033.1% | - |
| Book Value per Share | 0.28 | 1.19 | 2.50 | 3.27 | 9.31 | 12.99 | 14.53 | 14.97 | 19.71 | 15.55 | 14.89 | 16.60 | 2.42 | 0.13 |
| Total Shareholders' Equity | 10.59M | 37.21M | 70.87M | 88.1M | 262.1M | 356.43M | 396.73M | 405.01M | 486.37M | 307.58M | 39.27M | 42.34M | 5.99M | 145K |
| Common Stock | 30K | 28K | 30K | 27K | 29K | 28K | 27K | 27K | 27K | 24K | 3K | 3K | 17K | 17K |
| Retained Earnings | -641.56M | -772.56M | -759.33M | -614.1M | -450.48M | -321.75M | -263.96M | -244.03M | -146.69M | -85.03M | -54.92M | -50.66M | -45.26M | -48.79M |
| Treasury Stock | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Accumulated OCI | -151K | -24K | 305K | -797K | -5.25M | -422K | -4K | 338K | -223K | -426K | -3.8M | -3.58M | -3.35M | -3.11M |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quick answers to the most common questions about buying ANAB stock.
As of 2025, AnaptysBio, Inc. (ANAB) had total assets of $364.4M including $350.3M in current assets.
AnaptysBio, Inc. (ANAB) carries total debt of $14.1M, offset by $311.6M in cash and short-term investments. Comparing total debt to cash helps evaluate the company's debt burden and net leverage.
AnaptysBio, Inc. (ANAB) has total shareholders' equity (book value) of $37.2M ($1.19 book value per share). Book value represents the net worth of the company belonging to common stock holders.
AnaptysBio, Inc. (ANAB) reported a current ratio of 9.07x. A current ratio above 1.0x indicates that the company has more current assets than current liabilities, suggesting sufficient short-term liquidity.
Key Metrics
Top Statement Risk
Debt-funded capital allocation amid negative equity
Metrics are mathematically derived from official filings.
Debt Ballooned From Marginal to Dominant
Total debt surged from $15.1M in 2025Q2 to $346.4M by 2025Q3 — a nearly 23-fold expansion — before moderating to $269.6M in 2026Q2, with the debt-to-assets ratio now at 85.0%, per the reported balance sheets.
This appears to be a deliberate financing event rather than necessity-driven borrowing, given the timing relative to the equity trough of negative $44.7M in 2025Q2. However, at a D/E of 25.47, leverage is now extreme and the company's capacity to service this debt appears to depend heavily on milestone revenue that the income statement analysis has already flagged as lumpy and non-recurring. Investors should monitor whether debt maturity schedules create refinancing pressure before the internal pipeline generates sustainable cash flow.
Asset Base Shrinking Without Strategic Offset
Total assets have contracted from $493.4M in 2024Q3 to $317.0M in 2026Q2 — a 35.8% decline — with net PPE quietly eroding from $17.7M to $11.7M and zero goodwill recorded throughout, according to the company's quarterly filings.
The asset-light profile, with no goodwill or significant intangibles on the balance sheet, is consistent with the licensing-based business model and means there is no hidden impairment risk from acquired assets. However, the steady PPE decline without reinvestment may indicate underinvestment in the SHM platform's physical infrastructure, which warrants attention as the company pivots toward internal clinical execution.
Equity Wiped Out Then Partially Restored
Shareholders' equity collapsed to negative $44.7M in 2025Q2 before recovering to $10.6M in 2026Q2, while accumulated retained losses deepened to negative $837.3M at the trough and improved to negative $641.6M, per reported balance sheets.
The equity recovery appears to be driven by non-cash fair-value gains rather than operating profitability, consistent with the cash flow analysis showing that $183.9M of 2026Q2 net income failed to translate into positive operating cash flow. The fact that equity remains near zero against $269.6M of debt suggests the capital structure offers minimal cushion against further losses, making the balance sheet structurally fragile despite the headline improvement.
Cash Burn Outpacing Buffer Restoration
Cash reserves fell from $248.5M in 2026Q1 to $133.8M in 2026Q2 — a $114.7M sequential drawdown representing a 46.2% quarterly decline — even as the current ratio remained elevated at 5.61, based on the supplied balance sheet data.
The elevated current ratio masks a deteriorating liquidity trajectory, as the rapid cash depletion appears to outpace the milestone-driven revenue inflows. With cumulative free cash flow of approximately negative $169 million over ten quarters, the current cash position may represent less than a year of runway at recent burn rates, which reinforces the cash flow analysis finding that reported profitability has not converted into funding capacity.
Buybacks Funded While Debt Load Skyrocketed
Approximately $69 million in share repurchases were executed — concentrated in 2025Q2's $51.1 million outflow — during the same window when debt expanded from $15.1M to $346.4M, per the company's quarterly cash flow disclosures.
This capital allocation pattern is highly unusual for a company simultaneously experiencing negative equity and accumulating debt, and suggests either management conviction in the royalty stream's durability or a potential misallocation of capital relative to the company's stated clinical development needs. The distortion here is that headline equity recovery and the current ratio of 5.61 appear healthy in isolation, but the combination of buybacks, debt expansion, and negative operating cash flow suggests the balance sheet restoration may be more cosmetic than substantive, warranting closer scrutiny of management's capital deployment framework.