Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in APRE held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | AIGH Capital Management LLC | 1.0M | $775K | +174.1% | 15.637% | 0.16% |
| 2 | Vestal Point Capital, LP | 350K | $267K | β | 5.389% | 0.01% |
| 3 | SPHERA FUNDS MANAGEMENT LTD. | 270K | $206K | 0.0% | 4.157% | 0.03% |
| 4 | Nantahala Capital Management, LLC | 206K | $157K | 0.0% | 3.168% | 0.01% |
| 5 | GEODE CAPITAL MANAGEMENT, LLC | 119K | $91K | +190.9% | 1.834% | 0.00% |
| 6 | Scientech Research LLC | 60K | $46K | β | 0.928% | 0.04% |
| 7 | BNP PARIBAS ARBITRAGE, SA | 40K | $30K | +45.7% | 0.613% | 0.00% |
| 8 | VANGUARD FIDUCIARY TRUST CO | 38K | $29K | β | 0.592% | 0.00% |
| 9 | RENAISSANCE TECHNOLOGIES LLC | 25K | $19K | β | 0.387% | 0.00% |
| 10 | MORGAN STANLEY | 22K | $17K | -71.0% | 0.344% | 0.00% |
| 11 | LPL Financial LLC | 21K | $16K | -19.2% | 0.324% | 0.00% |
| 12 | VANGUARD CAPITAL MANAGEMENT LLC | 20K | $15K | β | 0.302% | 0.00% |
| 13 | HighTower Advisors, LLC | 14K | $11K | 0.0% | 0.214% | 0.00% |
| 14 | TWO SIGMA SECURITIES, LLC | 14K | $10K | β | 0.208% | 0.00% |
| 15 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 13K | $10K | β | 0.200% | 0.00% |
| 16 | BlackRock, Inc. | 9K | $6K | 0.0% | 0.131% | 0.00% |
| 17 | Tower Research Capital LLC (TRC) | 5K | $4K | -34.5% | 0.079% | 0.00% |
| 18 | UBS Group AG | 2K | $2K | -12.5% | 0.033% | 0.00% |
| 19 | GROUP ONE TRADING, L.P. | 577 | $440 | 0.0% | 0.009% | 0.00% |
| 20 | ADVISOR GROUP HOLDINGS, INC. | 295 | $225 | -1.7% | 0.005% | 0.00% |
| 21 | WealthCollab, LLC | 158 | $121 | 0.0% | 0.002% | 0.00% |
| 22 | SBI Securities Co., Ltd. | 16 | $12 | +6.7% | 0.000% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in APRE β a direct measure of their conviction.
Filings activity in APRE during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 22 | +4.8% | 38.43% | +8.28 pp | $2M | +27% |
| Q4 2025 | 21 | 8.7% | 30.15% | 23.03 pp | $1M | 43% |
| Q3 2025 | 23 | 4.2% | 53.18% | 15.76 pp | $2M | 23% |
| Q2 2025 | 24 | 11% | 68.94% | 15.96 pp | $3M | 19% |
| Q1 2025 | 27 | +3.8% | 84.90% | 68.30 pp | $4M | 45% |
| Q4 2024 | 26 | +24% | 153.20% | +29.81 pp | $7M | +24% |
| Q3 2024 | 21 | 22% | 123.39% | 66.80 pp | $5M | 35% |
| Q2 2024 | 27 | β | 190.19% | β | $8M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying APRE stock.
Based on Q1 2026 13F filings, institutional ownership of Aprea Therapeutics, Inc. stands at 38.4%, held across 22 reporting institutions.
AIGH Capital Management LLC is the largest reported institutional holder of APRE, with approximately 1,015,541 shares worth $0.00B as of Q1 2026.
Yes β 3 widely-followed marquee investors appear among the top 25 institutional holders of APRE, including RENAISSANCE TECHNOLOGIES LLC, TWO SIGMA SECURITIES, LLC, SUSQUEHANNA INTERNATIONAL GROUP, LLP.
Our composite Smart Money Score for APRE is 72 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
7 institutions opened new positions in APRE during Q1 2026, while 6 fully exited. 3 added to existing positions and 12 trimmed.
APRE institutional ownership rose by 8.28 percentage points quarter-over-quarter, with a net change of +1 holders.
The top 10 institutions account for 95.6% of all reported 13F value in APRE, and the top 25 account for 100.0%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Aprea Therapeutics, Inc. (APRE) Institutional Ownership