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AVTXAvalo Therapeutics, Inc.
$16.51$720M
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AVTX logo

Avalo Therapeutics, Inc.

AVTX
NASDAQ · Biotechnology
$16.51
At close - Sep 22, 4:00 PM EDT - USD
Market Cap$720M
P/E-2.8x
52W High$24.27
Volume585.1K
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q2

Phase 2 Success Offsets Accelerating Cash Burn

Avalo Therapeutics is a clinical-stage biotech whose lead asset, abdikibart, posted positive Phase 2 LOTUS results in hidradenitis suppurativa, de-risking the program and enabling a move toward registrational trials. The company's balance sheet was rebuilt via...

GrowthDecelerating
ProfitabilityNegative
ValuationReview
TechnicalsWeak
Explore valuation models
MARKET ACTION

AVTX price & volume

Price trend, volume and key moving averages

Launch Terminal
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Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

2/12 Beats

EPS beat 2 of last 12 quarters

02

Valuation risk

-107% Peers

P/E is 107% below peer median

03

Market leadership

RS 39 · Lag

Laggard (Underperforming 61% of market)

04

Weak Trend

Below 200DMA

Price < 200DMA

Next CatalystConfirmed earnings · Nov 5

Market performance

Price History →

Trailing total returns as of 9/23/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
AVTX-3.00%
S&P 500 (^GSPC)+13.20%
1-Year Return
AVTX+41.11%
S&P 500 (^GSPC)+15.98%
3-Year Return
AVTX-42.19%
S&P 500 (^GSPC)+64.59%
5-Year Return
AVTX-99.76%
S&P 500 (^GSPC)+78.78%

Growth & profitability

Annual revenue & EPS trend
Revenue
$59K-86.6% YoY
Net income
-$78M-122.8% YoY
Free cash flow
-$51M-4.9% YoY
Operating margin
-123601.7%-108066.1 pts YoY
ROIC (TTM)-159.3%
Avg ROIC 5Y-
ROE (TTM)-72.4%
Piotroski Score1 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate2/12 (18%)
Revenue Beat Rate0/12 (0%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Aug 6, 2026
-$0.83-42.4%
vs -$0.58
—
vs —
Q2 2026
May 13, 2026
-$0.98+2.0%
vs -$1.00
—
vs —
Q2 2026
Mar 23, 2026
-$0.74+51.9%
vs -$1.54
$79,500
vs —
Q4 2025
Nov 6, 2025
-$2.19-31.1%
vs -$1.67
—
vs —
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

5 Stories
GlobeNewsWire·Sep 4, 2026
Avalo Therapeutics Announces Inducement Grants to New Employees Under Nasdaq Listing Rule 5635(c)(4)

WAYNE, Pa., Sept. 04, 2026 (GLOBE NEWSWIRE) -- Avalo Therapeutics, Inc. (Nasdaq: AVTX), a clinical stage biotechnology company dedicated to developing therapeutics targeting the IL-1β pathway for immune-mediated inflammatory diseases, today announced the grant of inducement equity awards to six new employees. The Compensation Committee of the Board of Directors of Avalo approved the grants of nonstatutory stock options to purchase an aggregate of 78,000 shares of common stock (the “Options”) as inducements material to the employees entering into employment with the Company in accordance with Nasdaq Listing Rule 5635(c)(4).

Seeking Alpha·Sep 4, 2026
Avalo Therapeutics: Phase 2 Validation Has Created An IL-1β Franchise

Avalo Therapeutics (AVTX) is now a well-funded, registrational-stage biotech with validated Phase II data for abdakibart in hidradenitis suppurativa (HS). Abdakibart demonstrated statistically significant HiSCR75 response rates and clean safety, with monthly dosing and efficacy across both biologic-experienced and naive patients. AVTX's $472M cash position secures operations into 2029, reducing near-term dilution risk and enhancing negotiating leverage for Phase 3 and beyond.

GlobeNewsWire·Sep 3, 2026
Avalo Therapeutics to Participate in Upcoming Investor Conferences

WAYNE, Pa., Sept. 03, 2026 (GLOBE NEWSWIRE) -- Avalo Therapeutics, Inc. (Nasdaq: AVTX), a clinical stage biotechnology company dedicated to developing therapeutics targeting the IL-1β pathway for immune-mediated inflammatory diseases, today announced that management will participate in the following investor conferences:

GlobeNewsWire·Aug 6, 2026
Avalo Therapeutics Reports Second Quarter 2026 Financial Results and Recent Business Updates

WAYNE, Pa., Aug. 06, 2026 (GLOBE NEWSWIRE) -- Avalo Therapeutics, Inc. (Nasdaq: AVTX), a clinical stage biotechnology company dedicated to developing therapeutics targeting the IL-1β pathway for immune-mediated inflammatory diseases, today announced business updates and financial results for the second quarter of 2026.

Filtered for Avalo Therapeutics, Inc.More Headlines
04

Compare before deciding

Benchmark AVTX against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Avalo Therapeutics, Inc. (AVTX)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
AVTX logoAVTXAvalo Therapeutics, Inc.Current
$16.51$719.87M-2.83-86.62%-132642.37%-72.43%—
IMVT logoIMVTImmunovant, Inc.
$37.29$7.7B-13.46—-7585.86%-69.59%—
ARQT logoARQTArcutis Biotherapeutics, Inc.
$27.78$3.47B-213.6991.34%6.15%15.05%—
KYMR logoKYMRKymera Therapeutics, Inc.
$122.06$10.04B-33.08-16.72%-285.41%-21.5%—
PRAX logoPRAXPraxis Precision Medicines, Inc.
$300.65$8.38B-22.30-100%—-34.15%—
TARS logoTARSTarsus Pharmaceuticals, Inc.
$77.08$3.32B-48.48146.71%-7.67%-13.53%—

Compare AVTX vs Peers

Avalo Therapeutics, Inc. (AVTX) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs IMVT

Most directly comparable listed peer for AVTX.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare AVTX against a more recognizable public peer.

Peer Set

Compare Top 5

vs IMVT, ARQT, KYMR, PRAX

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

AVTX SEC Filings & Documents

Avalo Therapeutics, Inc. (AVTX) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Aug 6, 2026·SEC

Material company update

Jun 23, 2026·SEC

Material company update

Jun 16, 2026·SEC

10-K Annual Reports

2
FY 2026

Mar 23, 2026·SEC

FY 2025

Mar 20, 2025·SEC

10-Q Quarterly Reports

6
FY 2026

Aug 6, 2026·SEC

FY 2026

May 13, 2026·SEC

FY 2025

Nov 6, 2025·SEC

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AVTX Frequently Asked Questions

Avalo Therapeutics, Inc. (AVTX) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Avalo Therapeutics, Inc.'s revenue?

Avalo Therapeutics, Inc. (AVTX) reported $0.1M in revenue for fiscal year 2025. This represents a 29% decrease from $0.1M in 2012.

How fast is Avalo Therapeutics, Inc. growing?

Avalo Therapeutics, Inc. (AVTX) saw revenue decline by 86.6% over the past year.

Is AVTX profitable?

Avalo Therapeutics, Inc. (AVTX) reported a net loss of $100.3M for fiscal year 2025.

Dividend & Returns
What is AVTX's return on equity?

Avalo Therapeutics, Inc. (AVTX) has a return on equity (ROE) of -72.4%. Negative ROE indicates the company is unprofitable.

What is Avalo Therapeutics, Inc.'s free cash flow?

Avalo Therapeutics, Inc. (AVTX) had negative free cash flow of $66.4M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in AVTX back in 2012?

Total return calculator · dividends reinvested · 14+ years of data

See returns →