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AVTXAvalo Therapeutics, Inc.
$6.93$382M
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AVTX logo

Avalo Therapeutics, Inc.

AVTX
NASDAQ · Immunology Biotech
$6.93
At close - Nov 6, 4:00 PM EST - USD
Market Cap$382M
P/E-4.3x
52W High$24.27
Volume1.11M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q2

Phase 2 Success Offsets Accelerating Cash Burn

Avalo Therapeutics is a clinical-stage biotech whose lead asset, abdikibart, posted positive Phase 2 LOTUS results in hidradenitis suppurativa, de-risking the program and enabling a move toward registrational trials.

GrowthDecelerating
ProfitabilityNegative
ValuationReview
TechnicalsWeak
Explore valuation models
MARKET ACTION

AVTX price & volume

Price trend, volume and key moving averages

Launch Terminal
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Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

3/12 Beats

EPS beat 3 of last 12 quarters

02

Valuation risk

-111% Peers

P/E is 111% below peer median

03

Market leadership

RS 7 · Lag

Laggard (Underperforming 93% of market)

04

Weak Trend

Below 200DMA

Price < 200DMA

Next CatalystEstimated earnings · Feb 5

Market performance

Price History →

Trailing total returns as of 11/8/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
AVTX-59.28%
S&P 500 (^GSPC)+7.63%
1-Year Return
AVTX-55.06%
S&P 500 (^GSPC)+9.69%
3-Year Return
AVTX-71.41%
S&P 500 (^GSPC)+72.90%
5-Year Return
AVTX-99.90%
S&P 500 (^GSPC)+58.40%

Growth & profitability

Annual revenue & EPS trend
Revenue FY25
$59K-86.6% YoY
Net income FY25
-$78M-122.8% YoY
Free cash flow FY25
-$51M-4.9% YoY
Operating margin FY25
-123601.7%-108066.1 pts YoY
ROIC (FY25)-159.3%
Avg ROIC 5Y-2179.1%
ROE (TTM)-34.2%
Piotroski Score1 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate3/12 (27%)
Revenue Beat Rate0/12 (0%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q4 2026Latest
Nov 5, 2026
-$0.34+42.2%
vs -$0.59
—
vs —
Q3 2026
Aug 6, 2026
-$0.83-42.4%
vs -$0.58
—
vs —
Q2 2026
May 13, 2026
-$0.98+2.0%
vs -$1.00
—
vs —
Q2 2026
Mar 23, 2026
-$0.74+51.9%
vs -$1.54
$79,500
vs —
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

4 Stories
GlobeNewsWire·2d ago
Avalo Therapeutics Reports Third Quarter 2026 Financial Results and Recent Business Updates

Advancing abdakibart toward a registrational Phase 3 program in hidradenitis suppurativa, with initiation planned for the first half of 2027 Advancing AVTX-010, a next-generation, long-acting anti-IL-1β antibody, toward an Investigational New Drug submission in the first half of 2027 Cash, cash equivalents and investments of $462.8 million as of September 30, 2026 , expected to fund operations into 2029 WAYNE, Pa., Nov. 05, 2026 (GLOBE NEWSWIRE) -- Avalo Therapeutics, Inc. (Nasdaq: AVTX), a clinical-stage biotechnology company focused on developing therapies targeting the IL-1β pathway for immune-mediated inflammatory diseases, today reported financial results for the third quarter of 2026 and provided a business update.

GlobeNewsWire·5d ago
Avalo Therapeutics to Participate in Upcoming Investor Conferences

WAYNE, Pa., Nov. 02, 2026 (GLOBE NEWSWIRE) -- Avalo Therapeutics, Inc. (Nasdaq: AVTX), a clinical stage biotechnology company dedicated to developing therapeutics targeting the IL-1β pathway for immune-mediated inflammatory diseases, today announced that management will participate in the following investor conferences:

Seeking Alpha·Oct 25, 2026
Avalo Therapeutics: Contrarian 'Buy' Ahead Of Abdakibart's Phase 3

Avalo Therapeutics' positive LOTUS results now support a pivotal trial, and its monthly dosing gives it a potential differentiating factor in HS. Their balance sheet has enough runway to meet their upcoming milestones as well. AVTX-010 offers follow-on potential, but its planned IND submission means that it's still years away from becoming a meaningful value driver for AVTX.

Benzinga·Oct 23, 2026
This Avalo Therapeutics Analyst Is No Longer Bullish; Here Are Top 5 Downgrades For Friday

Top Wall Street analysts changed their outlook on these top names. For a complete view of all analyst rating changes, including upgrades, downgrades and initiations, please see our analyst ratings page.

Filtered for Avalo Therapeutics, Inc.More Headlines
04

Compare before deciding

Benchmark AVTX against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Avalo Therapeutics, Inc. (AVTX)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
AVTX logoAVTXAvalo Therapeutics, Inc.Current
$6.93$381.57M-4.30-86.62%-150259.32%-34.21%—
IMVT logoIMVTImmunovant, Inc.
$30.53$6.3B-11.66—-7585.86%-69.59%—
ARQT logoARQTArcutis Biotherapeutics, Inc.
$25.55$3.2B116.8891.34%5.88%14.18%—
KYMR logoKYMRKymera Therapeutics, Inc.
$131.73$10.84B-37.73-16.72%-341.87%-22.39%—
PRAX logoPRAXPraxis Precision Medicines, Inc.
$277.62$7.74B-23.85-100%—-34.15%—
TARS logoTARSTarsus Pharmaceuticals, Inc.
$68.60$2.95B-4.53146.71%-102.93%-245.72%—

Compare AVTX vs Peers

Avalo Therapeutics, Inc. (AVTX) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs IMVT

Most directly comparable listed peer for AVTX.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare AVTX against a more recognizable public peer.

Peer Set

Compare Top 5

vs IMVT, ARQT, KYMR, PRAX

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

AVTX SEC Filings & Documents

Avalo Therapeutics, Inc. (AVTX) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Aug 6, 2026·SEC

Material company update

Jun 23, 2026·SEC

Material company update

Jun 16, 2026·SEC

10-K Annual Reports

2
FY 2026

Mar 23, 2026·SEC

FY 2025

Mar 20, 2025·SEC

10-Q Quarterly Reports

6
FY 2026

Aug 6, 2026·SEC

FY 2026

May 13, 2026·SEC

FY 2025

Nov 6, 2025·SEC

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AVTX Frequently Asked Questions

Avalo Therapeutics, Inc. (AVTX) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
What is Avalo Therapeutics, Inc.'s revenue?

Avalo Therapeutics, Inc. (AVTX) reported $0.1M in revenue in fiscal year 2025, which is also its trailing twelve months. That is 29% less than the $0.1M of fiscal year 2012.

How fast is Avalo Therapeutics, Inc. growing?

Avalo Therapeutics, Inc. (AVTX) revenue fell by 69.3% over the trailing twelve months, compared with the twelve months before.

Is AVTX profitable?

No. Avalo Therapeutics, Inc. (AVTX) reported a net loss of $88.7M over the trailing twelve months.

Dividend & Returns
What is AVTX's return on equity?

Avalo Therapeutics, Inc. (AVTX) had a return on equity (ROE) of -34.2% over the trailing twelve months. A negative ROE means the company lost money over the period.

What is Avalo Therapeutics, Inc.'s free cash flow?

Avalo Therapeutics, Inc. (AVTX) had negative free cash flow of $61.6M over the trailing twelve months.

What if you invested $1,000 in AVTX back in 2012?

Total return calculator · dividends reinvested · 14+ years of data

See returns →