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AVTX logoAvalo Therapeutics, Inc.(AVTX)Earnings, Financials & Key Ratios

AVTX•NASDAQ
$21.81
$404M mkt cap·Price updated May 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryImmunology and Inflammation Therapies
AboutAvalo Therapeutics, Inc., a clinical-stage precision medicine company, discovers, develops, and commercializes targeted therapeutics for patients with unmet clinical need in immunology, immuno-oncology, and rare genetic diseases. It develops AVTX-002, a fully human anti-LIGHT monoclonal antibody, which is under Phase II clinical trial for the treatment of non-eosinophilic asthma, as well as inflammatory bowel disease, including moderate to severe Crohn's disease, and ulcerative colitis; and Phase III clinical trial for the treatment of COVID-19 acute respiratory distress syndrome. The company also engages in developing AVTX-007, a fully human Anti-IL-18 monoclonal antibody that is under Phase I clinical trial for the treatment of still's disease, including adult-onset still's disease and systemic juvenile idiopathic arthritis. Its products for rare genetic diseases in Phase III clinical trials include AVTX-801, a D-galactose substrate replacement therapy for the treatment of phosphoglucomutase 1 deficiency (PGM1), also known as PGM1-CDG; and AVTX-803, a L-fucose substrate replacement therapy for the treatment of LADII, also known as SLC35C1-CDG. The company was formerly known as Cerecor Inc. and changed its name to Avalo Therapeutics, Inc. in August 2021. Avalo Therapeutics, Inc. was incorporated in 2011 and is headquartered in Rockville, Maryland.Show more
  • Revenue$59K-86.6%
  • EBITDA-$73M-6.7%
  • Net Income-$78M-122.8%
  • EPS (Diluted)-5.84-79.1%
  • EBITDA Margin-123601.69%-697.6%
  • Operating Margin-123601.69%-695.6%
  • Net Margin-132642.37%-1565.2%
  • ROE-72.43%-44.7%
  • ROIC-165.13%
Technical→

AVTX Key Insights

Avalo Therapeutics, Inc. (AVTX) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

No significant strengths identified

✗Weaknesses

  • ✗Weak Piotroski F-Score: 1/9
  • ✗Negative free cash flow
  • ✗Sales declining 61.2% over 5 years
  • ✗Shares diluted 24.3% in last year
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

AVTX Price & Volume

Avalo Therapeutics, Inc. (AVTX) stock price & volume — 10-year historical chart

Loading chart...

AVTX Growth Metrics

Avalo Therapeutics, Inc. (AVTX) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-61.19%
3 Years-85.16%
TTM-147.39%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-122.78%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM94.95%

Return on Capital

10 Years-98.42%
5 Years-126.4%
3 Years-114.18%
Last Year-58.98%

AVTX Recent Earnings

Avalo Therapeutics, Inc. (AVTX) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 2/12 qtrs (18%)●Beat Revenue 1/12 qtrs (33%)
Q2 2026Latest
Mar 23, 2026
EPS
$0.37
Est $1.54
+76.0%
Revenue
$59,000
Est $59,000
+0.0%
Q4 2025
Nov 6, 2025
EPS
$2.19
Est $1.67
-31.1%
Revenue
—
Q3 2025
Aug 7, 2025
EPS
$1.92
Est $1.43
-34.3%
Revenue
—
Q2 2025
May 12, 2025
EPS
$1.25
Est $1.07
-16.8%
Revenue
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMar 23, 2026
$0.37vs $1.54+76.0%
$59,000vs $59,000+0.0%
Q4 2025Nov 6, 2025
$2.19vs $1.67-31.1%
—
Q3 2025Aug 7, 2025
$1.92vs $1.43-34.3%
—
Q2 2025May 12, 2025
$1.25vs $1.07-16.8%
—
Based on last 12 quarters of dataView full earnings history →

AVTX Peer Comparison

Avalo Therapeutics, Inc. (AVTX) competitors in Immunology and Inflammation Therapies — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
IMVT logoIMVTImmunovant, Inc.Direct Competitor5.83B28.67-10.50-47.07%0.00
ARQT logoARQTArcutis Biotherapeutics, Inc.Direct Competitor3.02B24.17-185.9291.34%-0.57%-1.41%0.03
KYMR logoKYMRKymera Therapeutics, Inc.Direct Competitor7.04B86.26-23.38-16.72%-6.12%-25.02%0.05
PRAX logoPRAXPraxis Precision Medicines, Inc.Direct Competitor7.61B337.95-25.07-100%-58.74%0.00
TARS logoTARSTarsus Pharmaceuticals, Inc.Direct Competitor2.76B64.76-40.73146.71%-9.02%-14.19%0.27
NUVL logoNUVLNuvalent, Inc.Direct Competitor6.92B104.26-26.53-45.12%
RCKT logoRCKTRocket Pharmaceuticals, Inc.Product Competitor418.11M3.86-1.92-80.49%0.09
ALDX logoALDXAldeyra Therapeutics, Inc.Product Competitor104.68M1.74-1.85-87.71%0.22

Compare AVTX vs Peers

Avalo Therapeutics, Inc. (AVTX) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs IMVT

Most directly comparable listed peer for AVTX.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare AVTX against a more recognizable public peer.

Peer Set

Compare Top 5

vs IMVT, ARQT, KYMR, PRAX

AVTX Income Statement

Avalo Therapeutics, Inc. (AVTX) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Sales/Revenue27.81M18.33M6.75M6.7M5.4M18.05M1.92M441K59K
Revenue Growth %2312.24%-34.11%-63.17%-0.76%-19.42%234.4%-89.34%-77.08%-86.62%
Cost of Goods Sold635.65K7.48M-566.52K300K1.49M3.43M1.28M-366K0
COGS % of Revenue2.29%40.81%-8.39%4.48%27.62%19.02%66.74%-82.99%-
Gross Profit
27.18M▲ 0%
10.85M▼ 60.1%
7.32M▼ 32.6%
6.4M▼ 12.5%
3.91M▼ 38.9%
14.62M▲ 274.1%
640K▼ 95.6%
807K▲ 26.1%
0▼ 100.0%
Gross Margin %97.71%59.19%108.39%95.52%72.38%80.98%33.26%182.99%-
Gross Profit Growth %483.54%-60.08%-32.55%-12.54%-38.94%274.12%-95.62%26.09%-100%
Operating Expenses13.29M29.52M23.45M6.4M86.04M52.06M27.99M69.32M72.98M
OpEx % of Revenue47.77%161.07%347.45%95.52%1593.94%288.39%1454.83%15718.59%123701.69%
Selling, General & Admin8.91M19.2M11.61M19.76M24.66M20.71M10.3M17.24M22.9M
SG&A % of Revenue32.05%104.76%171.95%294.95%456.8%114.74%535.34%3909.52%38813.56%
Research & Development4.37M5.79M11.76M32.19M59.84M31.31M13.78M52.08M50.08M
R&D % of Revenue15.72%31.57%174.27%480.56%1108.47%173.44%716.42%11809.07%84888.14%
Other Operating Expenses013.66K83.11K-45.55M1.55M38K3.91M00
Operating Income
13.89M▲ 0%
-39.31M▼ 383.0%
-16.14M▲ 59.0%
0▲ 100.0%
-82.13M▲ 0%
-37.44M▲ 54.4%
-27.35M▲ 26.9%
-68.51M▼ 150.5%
-72.92M▼ 6.4%
Operating Margin %49.94%-214.52%-239.06%--1521.56%-207.41%-1421.57%-15535.6%-123601.69%
Operating Income Growth %186.38%-383.04%58.95%100%-54.42%26.95%-150.49%-6.44%
EBITDA14.32M-37.46M-12.25M-45.45M-80.48M-37.27M-27.19M-68.34M-72.92M
EBITDA Margin %51.47%-204.41%-181.53%-678.47%-1490.87%-206.49%-1413.36%-15497.28%-123601.69%
EBITDA Growth %189.18%-361.69%67.29%-270.91%-77.06%53.68%27.05%-151.33%-6.7%
D&A (Non-Cash Add-back)425.48K1.85M3.88M1.84M1.66M166K158K169K0
EBIT13.89M-14.9M-17.39M-47.29M-82.13M-37.44M-23.44M-68.51M0
Net Interest Income-24.02K16.26K121.33K49K-2.39M-4.17M-3.42M3.32M0
Interest Income016.26K121.33K49K0003.32M0
Interest Expense24.02K0002.39M4.17M3.42M00
Other Income/Expense-53.64K54.93K147.29K-67.18M-2.41M-4.19M-4.18M33.5M-5.17M
Pretax Income
13.84M▲ 0%
-40.09M▼ 389.7%
-15.99M▲ 60.1%
-67.18M▼ 320.1%
-84.55M▼ 25.9%
-41.63M▲ 50.8%
-31.53M▲ 24.3%
-35.02M▼ 11.1%
-78.09M▼ 123.0%
Pretax Margin %49.75%-218.73%-236.88%-1002.79%-1566.23%-230.62%-1638.77%-7939.91%-132362.71%
Income Tax1.97M-33.91K280.32K-2.79M-196K28K14K114K165K
Effective Tax Rate %14.21%0.08%-1.75%4.16%0.23%-0.07%-0.04%-0.33%-0.21%
Net Income
11.87M▲ 0%
-40.05M▼ 437.4%
-16.07M▲ 59.9%
-63.5M▼ 295.1%
-84.38M▼ 32.9%
-41.66M▲ 50.6%
-31.54M▲ 24.3%
-35.13M▼ 11.4%
-78.26M▼ 122.8%
Net Margin %42.68%-218.55%-238.1%-947.9%-1563.1%-230.78%-1639.5%-7965.76%-132642.37%
Net Income Growth %172.06%-437.43%59.87%-295.08%-32.88%50.63%24.28%-11.37%-122.78%
Net Income (Continuing)11.87M-35.27M-16.27M-64.38M-84.35M-41.66M-31.54M-35.13M-78.26M
Discontinued Operations00198.21K884K-27K0000
Minority Interest000000000
EPS (Diluted)
1822.74▲ 0%
-3317.28▼ 282.0%
-819.74▲ 75.3%
-2523.77▼ 207.9%
-2330.66▲ 7.7%
-1062.65▲ 54.4%
-113.58▲ 89.3%
-3.26▲ 97.1%
-5.84▼ 79.1%
EPS Growth %8411.63%-281.99%75.29%-207.87%7.65%54.41%89.31%97.13%-79.14%
EPS (Basic)1856.88-3317.28-819.74-2523.77-2330.66-1062.65-113.58-4.32-5.84
Diluted Shares Outstanding6.51K12.07K19.85K25.51K36.19K39.2K277.73K10.78M13.4M
Basic Shares Outstanding6.39K12.07K19.85K25.51K36.19K39.2K277.73K8.13M13.4M
Dividend Payout Ratio---------

AVTX Balance Sheet

Avalo Therapeutics, Inc. (AVTX) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Total Current Assets10.99M21.93M17.72M26M61.84M16.42M8.39M138.89M105.29M
Cash & Short-Term Investments2.47M10.65M11.24M18.92M54.59M13.17M7.42M134.55M98.34M
Cash Only2.47M10.65M3.61M18.92M54.59M13.17M7.42M134.55M15.86M
Short-Term Investments007.63M0000082.48M
Accounts Receivable2.94M6.08M5.24M4.38M4.8M1.92M136K611K0
Days Sales Outstanding38.52121.18283.45238.92324.538.825.8505.7-
Inventory382.15K1.11M21.33K3K38K20K000
Days Inventory Outstanding219.4454.22-13.753.659.32.13---
Other Current Assets4.18M9.41M515.11K38K51K1.3M844K3.73M6.95M
Total Non-Current Assets32.13M48.32M18.38M17.75M18.37M16.95M12.6M11.84M11.17M
Property, Plant & Equipment44.61K586.51K1.45M1.61M2.69M2.41M1.97M1.21M460K
Fixed Asset Turnover623.45x31.25x4.66x4.17x2.00x7.49x0.98x0.36x0.13x
Goodwill14.29M16.41M14.41M14.41M14.41M14.41M10.5M10.5M10.5M
Intangible Assets17.66M31.24M2.43M1.58M38K0000
Long-Term Investments131.35K81.72K0000000
Other Non-Current Assets131.35K-91.24K101.94K149K1.23M131K131K131K210K
Total Assets
43.12M▲ 0%
70.25M▲ 62.9%
36.11M▼ 48.6%
43.76M▲ 21.2%
80.21M▲ 83.3%
33.37M▼ 58.4%
20.99M▼ 37.1%
150.73M▲ 618.0%
116.46M▼ 22.7%
Asset Turnover0.64x0.26x0.19x0.15x0.07x0.54x0.09x0.00x0.00x
Asset Growth %647.51%62.9%-48.6%21.17%83.33%-58.4%-37.08%618.01%-22.74%
Total Current Liabilities11.41M26.22M12.16M15.22M19.89M22.11M4.62M6.96M12.94M
Accounts Payable1.3M1.45M2.08M2.57M3.37M2.88M446K283K137K
Days Payables Outstanding745.970.58-1.34K3.13K824.74306.33126.78-282.23-
Short-Term Debt000005.93M000
Deferred Revenue (Current)02.03M00088K000
Other Current Liabilities8.71M21.14M5.57M4.57M4.32M3.18M3.06M3.24M12.94M
Current Ratio0.96x0.84x1.46x1.71x3.11x0.74x1.82x19.96x8.14x
Quick Ratio0.93x0.79x1.46x1.71x3.11x0.74x1.82x19.96x8.14x
Cash Conversion Cycle-487.94104.811.61K-2.89K-490.94-265.4---
Total Non-Current Liabilities3.86M23.13M2.95M3.97M37.24M22.17M9.07M10.74M20.47M
Long-Term Debt000032.83M13.49M000
Capital Lease Obligations000000000
Deferred Tax Liabilities7.14K69.24K85.98K90K113K141K155K270K434K
Other Non-Current Liabilities3.85M23.06M2.87M3.88M4.3M8.54M8.92M10.47M20.04M
Total Liabilities15.26M49.34M15.11M19.19M57.13M44.28M13.69M17.7M33.41M
Total Debt015.38M155.81K426K33.32M19.95M537K568K0
Net Debt-2.47M4.73M-3.45M-18.49M-21.27M6.78M-6.88M-133.98M-15.86M
Debt / Equity-0.74x0.01x0.02x1.44x-0.07x0.00x-
Debt / EBITDA---------
Net Debt / EBITDA-0.17x--------
Interest Coverage578.36x----34.35x-8.98x-8.00x--
Total Equity
27.86M▲ 0%
20.91M▼ 25.0%
21M▲ 0.4%
24.56M▲ 17.0%
23.08M▼ 6.0%
-10.91M▼ 147.3%
7.3M▲ 166.9%
133.03M▲ 1721.4%
83.05M▼ 37.6%
Equity Growth %13358.75%-24.95%0.42%16.99%-6.03%-147.29%166.92%1721.36%-37.57%
Book Value per Share4278.141731.631057.76962.80637.78-278.4326.3012.346.20
Total Shareholders' Equity27.86M20.91M21M24.56M23.08M-10.91M7.3M133.03M83.05M
Common Stock2.69M40.8K44.38K75K9K01K10K18K
Retained Earnings-58.17M-98.22M-114.29M-177.79M-262.17M-303.82M-335.13M-370.26M-448.52M
Treasury Stock000000000
Accumulated OCI2.66M000000068K
Minority Interest000000000

AVTX Cash Flow Statement

Avalo Therapeutics, Inc. (AVTX) cash flow — operating, investing & free cash flow history

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Cash from Operations12.52M-3.13M-19.13M-40.54M-70.89M-26.75M-30.68M-49.06M-51.46M
Operating CF Margin %45.01%-17.07%-283.46%-605.15%-1313.3%-148.2%-1594.59%-11123.81%-87216.95%
Operating CF Growth %185.91%-124.99%-511.69%-111.87%-74.87%62.27%-14.69%-59.9%-4.9%
Net Income11.87M-40.05M-16.07M-63.5M-84.38M-41.66M-31.54M-35.13M-78.26M
Depreciation & Amortization425.48K4.55M3.88M1.84M1.66M166K158K169K344K
Stock-Based Compensation1.16M2.43M2.53M6.79M8.17M7.55M3.48M5.85M13.62M
Deferred Taxes-832.63K-16.75K16.74K197K22K28K14K114K165K
Other Non-Cash Items366.23K21.22M-7.47M18.57M794K7.22M6.46M-15.35M12.67M
Working Capital Changes-466.75K8.73M-2.03M-4.44M2.84M-60K-9.24M-4.71M0
Change in Receivables-247.19K-222.53K6.78M-2.79M1.12M2.88M1.78M-475K0
Change in Inventory-202.62K-311.2K532.95K18K-35K18K20K00
Change in Payables96.06K82.45K1.02M99K796K-487K-2.44M-163K-146K
Cash from Investing-18.91M865.46K-443K11.13M-113K-95K-133K356K-81.72M
Capital Expenditures-23.32K-564.41K-262.01K-63K-113K-95K-158K00
CapEx % of Revenue0.08%3.08%3.88%0.94%2.09%0.53%8.21%--
Acquisitions-18.89M1.43M011.2M000356K0
Investments---------
Other Investing0-1K-180.99K00025K0690K
Cash from Financing3.74M10.4M12.56M44.78M106.76M-14.7M25.04M175.85M14.59M
Debt Issued (Net)-2.37M0-256.14K032.9M-14.81M-21.24M00
Equity Issued (Net)6.34M3.86M12.68M44.45M71.93M107K46.22M115.63M0
Dividends Paid000000000
Share Repurchases0000000023K
Other Financing-232.38K6.55M131.07K332K1.93M067K60.22M14.59M
Net Change in Cash
-2.66M▲ 0%
8.14M▲ 406.5%
-7.02M▼ 186.2%
15.38M▲ 319.1%
35.76M▲ 132.5%
-41.45M▼ 215.9%
-5.77M▲ 86.1%
127.15M▲ 2303.2%
-118.59M▼ 193.3%
Free Cash Flow
12.5M▲ 0%
-3.69M▼ 129.5%
-19.4M▼ 425.3%
-40.6M▼ 109.3%
-71M▼ 74.9%
-26.85M▲ 62.2%
-30.84M▼ 14.9%
-49.06M▼ 59.1%
-51.46M▼ 4.9%
FCF Margin %44.93%-20.15%-287.34%-606.09%-1315.39%-148.72%-1602.81%-11123.81%-87216.95%
FCF Growth %185.54%-129.55%-425.29%-109.33%-74.88%62.19%-14.87%-59.08%-4.9%
FCF per Share1918.91-305.82-977.20-1591.55-1961.95-684.81-111.04-4.55-3.84
FCF Conversion (FCF/Net Income)1.05x0.08x1.19x0.64x0.84x0.64x0.97x1.40x0.66x
Interest Paid72.53K525K1.05M000000
Taxes Paid540K354K1.8M474K00000

AVTX Key Ratios

Avalo Therapeutics, Inc. (AVTX) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric2016201720182019202020212022202320242025
Return on Equity (ROE)-247.85%84.58%-164.26%-76.71%-278.77%-354.19%-684.77%-431.87%-50.06%-72.43%
Return on Invested Capital (ROIC)-91.3%-115.57%-56.06%--1562.67%--4815.32%--165.13%
Gross Margin-614.57%97.71%59.19%108.39%95.52%72.38%80.98%33.26%182.99%-
Net Margin-1428.53%42.68%-218.55%-238.1%-947.9%-1563.1%-230.78%-1639.5%-7965.76%-132642.37%
Debt / Equity11.37x-0.74x0.01x0.02x1.44x-0.07x0.00x-
Interest Coverage-34.64x578.36x----34.35x-8.98x-8.00x--
FCF Conversion0.88x1.05x0.08x1.19x0.64x0.84x0.64x0.97x1.40x0.66x
Revenue Growth-2312.24%-34.11%-63.17%-0.76%-19.42%234.4%-89.34%-77.08%-86.62%

AVTX SEC Filings & Documents

Avalo Therapeutics, Inc. (AVTX) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Mar 27, 2026·SEC

Material company update

Mar 23, 2026·SEC

Material company update

Jan 12, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 23, 2026·SEC

FY 2025

Mar 20, 2025·SEC

FY 2024

Mar 29, 2024·SEC

10-Q Quarterly Reports

6
FY 2025

Nov 6, 2025·SEC

FY 2025

Aug 7, 2025·SEC

FY 2025

May 12, 2025·SEC

AVTX Frequently Asked Questions

Avalo Therapeutics, Inc. (AVTX) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Avalo Therapeutics, Inc. (AVTX) reported $-0.2M in revenue for fiscal year 2025. This represents a 353% decrease from $0.1M in 2012.

Avalo Therapeutics, Inc. (AVTX) saw revenue decline by 86.6% over the past year.

Avalo Therapeutics, Inc. (AVTX) reported a net loss of $78.3M for fiscal year 2025.

Dividend & Returns

Avalo Therapeutics, Inc. (AVTX) has a return on equity (ROE) of -72.4%. Negative ROE indicates the company is unprofitable.

Avalo Therapeutics, Inc. (AVTX) had negative free cash flow of $51.5M in fiscal year 2025, likely due to heavy capital investments.

Explore More AVTX

Avalo Therapeutics, Inc. (AVTX) financial analysis — history, returns, DCA and operating performance tools

Total Return Calculator

Historical returns with dividends reinvested

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Dividend History

Yield, growth, payout safety & DRIP

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Earnings History

EPS trends, net income & profitability

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Price History

Long-term charts & historical price data

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Revenue History

Sales growth patterns & revenue breakdown

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Financial Ratios

30 years of market, efficiency and balance-sheet ratios

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Valuation

DCF intrinsic value, peer multiples & estimates

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