| Caligan Partners LP |
| 3.2M |
| $58.5M |
| +93.5% |
| 7.256% |
| 2.75% |
| 5 | TCG Crossover Management, LLC | 3.0M | $55.8M | +308.6% | 6.920% | 1.34% |
| 6 | Affinity Asset Advisors, LLC | 2.9M | $53.6M | +116.3% | 6.651% | 2.42% |
| 7 | STATE STREET CORP | 2.9M | $53.4M | +3932.3% | 6.627% | 0.00% |
| 8 | FARALLON CAPITAL MANAGEMENT, L.L.C. | 2.5M | $46.2M | +172.7% | 5.729% | 0.21% |
| 9 | Point72 Asset Management, L.P. | 2.4M | $44.1M | +160.5% | 5.475% | 0.05% |
| 10 | Avoro Capital Advisors LLC | 2.3M | $43.1M | +65.5% | 5.351% | 0.39% |
| 11 | VANGUARD CAPITAL MANAGEMENT LLC | 2.3M | $41.8M | +214.6% | 5.193% | 0.00% |
| 12 | BVF INC/IL | 2.1M | $38.4M | +27.1% | 4.760% | 0.98% |
| 13 | BANK OF AMERICA CORP /DE/ | 1.9M | $35.4M | +197.6% | 4.389% | 0.00% |
| 14 | Nantahala Capital Management, LLC | 1.9M | $34.4M | +50.8% | 4.271% | 0.57% |
| 15 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 1.7M | $32.0M | +102.5% | 3.965% | 0.04% |
| 16 | Soleus Capital Management, L.P. | 1.7M | $30.6M | +274.4% | 3.796% | 1.05% |
| 17 | BRAIDWELL LP | 1.6M | $30.1M | — | 3.737% | 1.11% |
| 18 | ALLIANCEBERNSTEIN L.P. | 1.3M | $23.3M | — | 2.891% | 0.01% |
| 19 | UBS Group AG | 1.2M | $22.3M | +5.9% | 2.773% | 0.00% |
| 20 | Logos Global Management LP | 1.1M | $21.3M | -11.5% | 2.637% | 0.91% |
| 21 | GEODE CAPITAL MANAGEMENT, LLC | 1.1M | $20.4M | +550.5% | 2.535% | 0.00% |
| 22 | Commodore Capital LP | 1.0M | $18.8M | +110.8% | 2.336% | 1.12% |
| 23 | RA CAPITAL MANAGEMENT, L.P. | 1.0M | $18.5M | +50.8% | 2.293% | 0.16% |
| 24 | GOLDMAN SACHS GROUP INC | 946K | $17.5M | +1474.4% | 2.170% | 0.00% |
| 25 | Trails Edge Capital Partners, LP | 892K | $16.5M | — | 2.046% | 2.62% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in AVTX — a direct measure of their conviction.
Institutions that fully closed their AVTX position in Q2 2026
| 18.93% |
| +1.66 pp |
| $66M |
| +19% |
| Q4 2024 | 34 | +13% | 17.27% | +2.00 pp | $56M | 12% |
| Q3 2024 | 30 | — | 15.27% | — | $63M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
AVTX institutional ownership rose by 85.74 percentage points quarter-over-quarter, with a net change of +27 holders.
The top 10 institutions account for 45.9% of all reported 13F value in AVTX, and the top 25 account for 76.7%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Avalo Therapeutics, Inc. (AVTX) Institutional Ownership