Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in AVTX held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 2.9M | $43.0M | +1207.1% | 25.495% | 0.00% |
| 2 | Caligan Partners LP | 1.6M | $24.4M | +85.5% | 14.477% | 1.70% |
| 3 | BVF INC/IL | 1.6M | $24.4M | +20.5% | 14.458% | 0.78% |
| 4 | Avoro Capital Advisors LLC | 1.4M | $21.1M | β | 12.484% | 0.22% |
| 5 | Affinity Asset Advisors, LLC | 1.3M | $20.0M | +27.6% | 11.872% | 1.16% |
| 6 | Logos Global Management LP | 1.3M | $19.4M | β | 11.510% | 0.97% |
| 7 | Nantahala Capital Management, LLC | 1.2M | $18.4M | 0.0% | 10.935% | 0.95% |
| 8 | UBS Group AG | 1.1M | $17.0M | +139.0% | 10.111% | 0.00% |
| 9 | Caption Management, LLC | 1.1M | $16.2M | β | 9.622% | 0.16% |
| 10 | Point72 Asset Management, L.P. | 916K | $13.7M | +46.0% | 8.112% | 0.02% |
| 11 | FARALLON CAPITAL MANAGEMENT LLC | 916K | $13.7M | β | 8.110% | 0.09% |
| 12 | RTW INVESTMENTS, LP | 857K | $12.8M | β | 7.588% | 0.13% |
| 13 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 854K | $12.8M | +55.3% | 7.562% | 0.02% |
| 14 | MILLENNIUM MANAGEMENT LLC | 835K | $12.5M | +26.6% | 7.397% | 0.01% |
| 15 | TCG Crossover Management, LLC | 738K | $11.0M | +52.9% | 6.538% | 0.32% |
| 16 | BALYASNY ASSET MANAGEMENT LLC | 732K | $10.9M | +66.5% | 6.478% | 0.04% |
| 17 | VANGUARD CAPITAL MANAGEMENT LLC | 720K | $10.7M | β | 6.372% | 0.00% |
| 18 | RA CAPITAL MANAGEMENT, L.P. | 663K | $9.9M | 0.0% | 5.870% | 0.10% |
| 19 | BANK OF AMERICA CORP /DE/ | 643K | $9.6M | +3.5% | 5.693% | 0.00% |
| 20 | BOOTHBAY FUND MANAGEMENT, LLC | 486K | $7.3M | +121.6% | 4.301% | 0.18% |
| 21 | COMMODORE CAPITAL LP | 483K | $7.2M | 0.0% | 4.277% | 0.42% |
| 22 | ORBIMED ADVISORS LLC | 475K | $7.1M | -60.0% | 4.207% | 0.15% |
| 23 | JENNISON ASSOCIATES LLC | 471K | $7.0M | -1.0% | 4.168% | 0.00% |
| 24 | Soleus Capital Management, L.P. | 442K | $6.6M | 0.0% | 3.913% | 0.27% |
| 25 | BNP PARIBAS ARBITRAGE, SA | 423K | $6.3M | +113.8% | 3.743% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in AVTX β a direct measure of their conviction.
Filings activity in AVTX during Q1 2026, grouped by how each filer changed its position.
Institutions that opened a new AVTX position in Q1 2026
Institutions that fully closed their AVTX position in Q1 2026
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 94 | +13% | 199.99% | +0.00 pp | $453M | +25% |
| Q4 2025 | 83 | +26% | 199.99% | +82.05 pp | $363M | +85% |
| Q3 2025 | 66 | +83% | 117.94% | +94.46 pp | $197M | +402% |
| Q2 2025 | 36 | +2.9% | 23.48% | 16.14 pp | $39M | 41% |
| Q1 2025 | 35 | +2.9% | 39.62% | +6.23 pp | $66M | +19% |
| Q4 2024 | 34 | +13% | 33.39% | 4.52 pp | $56M | 12% |
| Q3 2024 | 30 | +43% | 37.91% | +36.18 pp | $63M | +2088% |
| Q2 2024 | 21 | β | 1.73% | β | $3M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying AVTX stock.
Based on Q1 2026 13F filings, institutional ownership of Avalo Therapeutics, Inc. stands at 200.0%, held across 94 reporting institutions.
FMR LLC is the largest reported institutional holder of AVTX, with approximately 2,879,481 shares worth $0.04B as of Q1 2026.
Yes β 2 widely-followed marquee investors appear among the top 25 institutional holders of AVTX, including Point72 Asset Management, L.P., MILLENNIUM MANAGEMENT LLC.
Our composite Smart Money Score for AVTX is 58 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
34 institutions opened new positions in AVTX during Q1 2026, while 23 fully exited. 21 added to existing positions and 39 trimmed.
AVTX institutional ownership rose by 0.00 percentage points quarter-over-quarter, with a net change of +11 holders.
The top 10 institutions account for 48.0% of all reported 13F value in AVTX, and the top 25 account for 80.1%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Avalo Therapeutics, Inc. (AVTX) Institutional Ownership