Bull case
The bull case requires both strong earnings delivery and the market pricing BBIO more generously than it does today.
Wall Street verdict, consensus price target, and analyst rating breakdown — everything needed to frame the risk/reward at today's price.
Three scenarios for where BBIO stock could go
The bull case requires both strong earnings delivery and the market pricing BBIO more generously than it does today.
The base case reflects analyst consensus expectations — steady delivery without requiring a major catalyst or re-rating.
The bear case reflects a scenario where earnings shortfalls or multiple compression combine to materially reduce the stock from its current level.
Not financial advice. Model confidence reflects internal scenario assumptions, not a guarantee of returns. Past performance does not predict future results.

BridgeBio Pharma is a biopharmaceutical company focused on discovering and developing precision medicines for genetic diseases. It generates revenue primarily through drug development partnerships and potential future product sales — though currently in pre-revenue stage with multiple programs in clinical trials. The company's key advantage is its efficient hub-and-spoke operating model that allows rapid development of targeted therapies for rare genetic conditions.
Quarterly beat-or-miss track record against analyst estimates, plus forward revenue and EPS outlook for the next two fiscal years.
| Quarter | EPS (Actual / Est) | EPS Surprise | Revenue (Actual / Est) | Rev Surprise |
|---|---|---|---|---|
| Q3 2025 | $-0.95/$-0.83 | -14.5% | $111M/$108M | +2.3% |
| Q4 2025 | $-0.95/$-0.88 | -8.0% | $121M/$148M | -18.5% |
| Q1 2026 | $-1.00/$-0.71 | -40.2% | $154M/$147M | +5.0% |
| Q2 2026 | $-0.84/$-0.68 | -23.8% | $195M/$178M | +9.2% |
BBIO beat EPS estimates in 0 of 4 tracked quarters. Mixed delivery makes the upcoming report a key data point for re-rating.
Product and geographic revenue mix from the latest annual disclosure, with year-over-year growth by segment.
Latest annual revenue by segment or product family
Tap, hover, or focus a slice to inspect segment detail.
Latest annual revenue by reported region
Current multiples compared to the S&P 500, the company's sector, and its own five-year average.
Benchmark comparison across market, sector, and history below.
| Metric | BBIO | S&P 500 | Healthcare | 5Y Avg BBIO |
|---|---|---|---|---|
| Forward PE | — | 18.8x | 18.3x | — |
| Trailing PE | -17.5x | 24.4x-172% | 22.1x-179% | — |
| PEG Ratio | — | 1.66x | 1.59x | — |
| EV/EBITDA | — | 15.2x | 14.2x | — |
| Price/FCF | — | 20.7x | 18.5x | — |
| Price/Sales | 25.9x | 3.1x+736% | 2.6x+881% | 25.5x |
| Dividend Yield | — | 1.91% | 1.50% | — |
Forward P/E and PEG reflect analyst consensus estimates. Historical averages use trailing ratios where forward data is unavailable.S&P 500 and sector benchmarks both use trailing median P/E — similar readings indicate the broader index and sector are priced alike.
Open valuation toolKey financial metrics for BBIO are shown below.
Revenue, margins, and cash generation
ROIC, leverage, and debt serviceability
How capital is returned to owners
All figures from the trailing twelve months. ROIC uses invested capital (equity + net debt).
Open full ratios pageKey factors that could pressure the stock price, compress the multiple, or weigh on future results.
AI analysis · updated June 18, 2026
Negative Earnings Yield and Altman Z-score indicate significant financial distress and potential insolvency risk.
High growth potential from its new heart drug is offset by high cash burn and significant financial risks.
Investors should track pipeline execution, particularly the planned NDA submission for encaleret in the first half to the FDA, followed by an EMA filing.
Market reaction to earnings uncertainty led to a 15.24% drop as investors reacted to growing uncertainty around its upcoming fourth quarter and full year 2025 results.
Despite a negative DCF value and Graham Number, the market has priced it with a Forward P/E suggesting optimism for future earnings.
These are risk mechanisms, not predictions. The key question is which would force a cut to earnings estimates or a lower multiple than the market currently prices in.
Structural drivers behind the upside case and why the stock could outperform over the next 12 months.
AI analysis · updated June 18, 2026
Interim Phase 3 FORTIFY trial data for BBP-418 in limb-girdle muscular dystrophy type 2I/R9 met efficacy endpoints, indicating strong clinical progress.
BridgeBio Pharma's Attruby has shown a strong U.S. launch, contributing to favorable competitive dynamics and revenue growth.
Analysts maintain a Buy rating on BBIO, citing strong clinical and commercial performance as key drivers.
Expanded results from the Phase 3 FORTIFY trial are anticipated, which could further validate BBP-418's efficacy and market potential.
A real bull case compounds — each driver matters most when it strengthens margins, supports capital returns, and keeps the company above the market's minimum growth bar simultaneously.
52-week range context and price returns across multiple time horizons. Dividend contribution is shown separately in the Capital Return section.
Range context matters because valuation compression and earnings misses rarely hit from the same starting point. A stock already far below its high can still fall, but it is no longer carrying the same embedded optimism as one pressing a fresh peak.
Valuation, growth, and margin comparison against the closest publicly traded peers for this company.
| Company | Mkt Cap | Fwd PE | Rev Grw | Margin | Rating | Upside |
|---|---|---|---|---|---|---|
BBI BBIO BridgeBio Pharma, Inc. | $13.0B | — | +26.3% | -125.2% | Buy | +57.8% |
KYM KYMR Kymera Therapeutics, Inc. | $7.4B | — | +23.7% | -612.2% | Buy | +24.5% |
ARR ARRY Array Technologies, Inc. | $1.2B | 11.0x | +15.1% | -5.6% | Buy | +22.5% |
RCU RCUS Arcus Biosciences, Inc. | $2.4B | — | +35.0% | -156.4% | Buy | +27.5% |
PRA PRAX Praxis Precision Medicines, Inc. | $8.2B | — | +14.7% | — | Buy | +106.9% |
VRT VRTX Vertex Pharmaceuticals Incorporated | $114.9B | 23.4x | +11.0% | 35.4% | Buy | +22.7% |
This peer comparison reflects companies with similar business models, product lines, or market positioning, supplemented by industry grouping when direct matches are limited.
BBIO returns 0.4% annually — null% through dividends and 0.4% through buybacks.
Yield, cadence, and growth quality
How much per-share support comes from repurchases
Common questions answered from live analyst data and company financials.
BridgeBio Pharma, Inc. (BBIO) is rated Buy by Wall Street analysts as of 2026. Of 26 analysts covering the stock, 24 rate it Buy or Strong Buy, 2 rate it Hold, and 0 rate it Sell or Strong Sell. The consensus 12-month price target is $105, implying +57.8% from the current price of $66.
The Wall Street consensus price target for BBIO is $105 based on 26 analyst estimates. The high-end target is $157 (+136.9% from today), and the low-end target is $83 (+25.2%).
Forward earnings data for BBIO is not currently available. Review the valuation table above for trailing P/E, EV/EBITDA, and price-to-sales comparisons against market and sector benchmarks.
The primary risks for BBIO in 2026 are: (1) Financial Distress — Negative Earnings Yield and Altman Z-score indicate significant financial distress and potential insolvency risk. (2) Cash Burn — High growth potential from its new heart drug is offset by high cash burn and significant financial risks. (3) Pipeline Execution — Investors should track pipeline execution, particularly the planned NDA submission for encaleret in the first half to the FDA, followed by an EMA filing. Each factor has the potential to pressure earnings or compress the stock's valuation multiple.
Analyst consensus estimates BBIO will report consensus revenue of $732M (+26.3% year-over-year) and EPS of $-0.88 (+76.3% year-over-year) for the upcoming fiscal year. The following year, analysts project $931M in revenue.
BridgeBio Pharma, Inc. is expected to report its next earnings on approximately 2026-08-04. Consensus expects EPS of $-0.63 and revenue of $220M. Over recent quarters, BBIO has beaten EPS estimates 33% of the time.
BridgeBio Pharma, Inc. (BBIO) had a free cash outflow of $454M in free cash flow over the trailing twelve months — a free cash flow margin of 78.3%. BBIO returns capital to shareholders through and share repurchases ($48M TTM).