Bull case
The bull case requires both strong earnings delivery and the market pricing BBIO more generously than it does today.
Wall Street verdict, consensus price target, and analyst rating breakdown — everything needed to frame the risk/reward at today's price.
Three scenarios for where BBIO stock could go
The bull case requires both strong earnings delivery and the market pricing BBIO more generously than it does today.
The base case reflects analyst consensus expectations — steady delivery without requiring a major catalyst or re-rating.
The bear case reflects a scenario where earnings shortfalls or multiple compression combine to materially reduce the stock from its current level.
Not financial advice. Model confidence reflects internal scenario assumptions, not a guarantee of returns. Past performance does not predict future results.

BridgeBio Pharma is a biopharmaceutical company focused on discovering and developing precision medicines for genetic diseases. It generates revenue primarily through drug development partnerships and potential future product sales — though currently in pre-revenue stage with multiple programs in clinical trials. The company's key advantage is its efficient hub-and-spoke operating model that allows rapid development of targeted therapies for rare genetic conditions.
Quarterly beat-or-miss track record against analyst estimates, plus forward revenue and EPS outlook for the next two fiscal years.
| Quarter | EPS (Actual / Est) | EPS Surprise | Revenue (Actual / Est) | Rev Surprise |
|---|---|---|---|---|
| Q2 2025 | $-0.88/$-1.00 | +12.0% | $117M/$68M | +70.5% |
| Q3 2025 | $-0.95/$-0.83 | -14.5% | $111M/$108M | +2.3% |
| Q4 2025 | $-0.95/$-0.88 | -8.0% | $121M/$148M | -18.5% |
| Q1 2026 | $-1.00/$-0.71 | -40.2% | $154M/$147M | +5.0% |
BBIO beat EPS estimates in 1 of 4 tracked quarters. Mixed delivery makes the upcoming report a key data point for re-rating.
Product and geographic revenue mix from the latest annual disclosure, with year-over-year growth by segment.
Latest annual revenue by segment or product family
Tap, hover, or focus a slice to inspect segment detail.
Latest annual revenue by reported region
Current multiples compared to the S&P 500, the company's sector, and its own five-year average.
Fair value est. $201 — implies +193.2% from today's price.
| Metric | BBIO | S&P 500 | Healthcare | 5Y Avg BBIO |
|---|---|---|---|---|
| Forward PE | — | 19.1x | 19.0x | — |
| Trailing PE | -18.0x | 25.2x-171% | 22.1x-181% | — |
| PEG Ratio | — | 1.75x | 1.52x | — |
| EV/EBITDA | — | 15.3x | 14.1x | — |
| Price/FCF | — | 21.3x | 18.7x | — |
| Price/Sales | 26.4x | 3.1x+743% | 2.8x+827% | 25.5x |
| Dividend Yield | — | 1.88% | 1.40% | — |
Forward P/E and PEG reflect analyst consensus estimates. Historical averages use trailing ratios where forward data is unavailable.S&P 500 and sector benchmarks both use trailing median P/E — similar readings indicate the broader index and sector are priced alike.
Open valuation toolKey financial metrics for BBIO are shown below.
Revenue, margins, and cash generation
ROIC, leverage, and debt serviceability
How capital is returned to owners
All figures from the trailing twelve months. ROIC uses invested capital (equity + net debt).
Open full ratios pageKey factors that could pressure the stock price, compress the multiple, or weigh on future results.
AI analysis · updated April 29, 2026
BridgeBio Pharma relies heavily on a pipeline of drug candidates, with no currently approved products on the market. This creates significant uncertainty regarding future revenue streams and the success of its research and development efforts.
The company's financial strength is rated poorly, posing a potential risk for investors. BridgeBio has negative shareholders' equity, which could impact its ability to fund operations and growth.
Significant insider selling has been observed, with insiders selling approximately $27.7 million worth of shares in the past three months without any corresponding purchases. This could indicate a lack of confidence from those closest to the company.
While some products like HypoThermosol® are not subject to specific FDA pre-market approval, there is no assurance that FDA approval won't be required in the future for other products. This uncertainty could impact the company's ability to bring products to market.
BBIO's stock is subject to market volatility, and a general 'risk-off' sentiment can put pressure on its shares. This is particularly relevant during periods when traders reassess optimism around key events like patent trials.
BridgeBio's lack of diversification and heavy dependence on specific drug candidates, such as Attruby for achondroplasia, poses a significant risk. Failure of these candidates could severely impact the company's financial health.
BBIO's high P/S ratio suggests that investors are paying a premium for its sales, indicating high growth expectations that may not be met. Some analysts consider the stock to be slightly overvalued, which could lead to price corrections.
The biopharmaceutical industry is highly competitive, and BridgeBio faces significant competition for its drug candidates. This competition could hinder the company's ability to capture market share and achieve projected revenues.
These are risk mechanisms, not predictions. The key question is which would force a cut to earnings estimates or a lower multiple than the market currently prices in.
Structural drivers behind the upside case and why the stock could outperform over the next 12 months.
AI analysis · updated April 29, 2026
Attruby (acoramidis), a treatment for transthyretin amyloid cardiomyopathy (ATTR-CM), has exceeded revenue expectations, with Q1 revenue tripling analyst estimates. Analysts project significant revenue growth for the drug in 2025 and 2026, positioning it as best-in-class for an underserved heart-failure population.
BridgeBio has a diverse pipeline with four late-stage programs targeting Mendelian disorders, oncology, and gene therapy. The company has filed an NDA for BBP-418, an oral therapy for limb-girdle muscular dystrophy type 2I/R9, with future FDA approvals anticipated for encaleret and ribitol, potentially leading to significant profitability by 2027.
A significant majority of analysts covering BBIO have a 'Buy' or 'Strong Buy' rating, indicating strong confidence in the stock. The consensus price target suggests considerable upside potential, driven by the company's robust pipeline and revenue potential from its drugs.
Despite current losses, BridgeBio maintains a healthy liquidity cushion with substantial cash reserves, enabling continued investment in R&D and commercialization. The company also boasts a high gross margin, supporting its financial stability.
While short-term trading may show mixed returns, the stock has demonstrated strong long-term performance, with significant total shareholder returns over the past year and three years.
A real bull case compounds — each driver matters most when it strengthens margins, supports capital returns, and keeps the company above the market's minimum growth bar simultaneously.
52-week range context and price returns across multiple time horizons. Dividend contribution is shown separately in the Capital Return section.
Range context matters because valuation compression and earnings misses rarely hit from the same starting point. A stock already far below its high can still fall, but it is no longer carrying the same embedded optimism as one pressing a fresh peak.
Valuation, growth, and margin comparison against the closest publicly traded peers for this company.
| Company | Mkt Cap | Fwd PE | Rev Grw | Margin | Rating | Upside |
|---|---|---|---|---|---|---|
BBI BBIO BridgeBio Pharma, Inc. | $13.3B | — | +54.3% | -145.3% | Buy | +47.7% |
KYM KYMR Kymera Therapeutics, Inc. | $7.0B | — | -16.7% | -612.2% | Buy | +35.7% |
ARR ARRY Array Technologies, Inc. | $1.2B | 11.6x | +17.1% | -5.6% | Buy | +12.9% |
RCU RCUS Arcus Biosciences, Inc. | $2.6B | — | -5.0% | -156.4% | Buy | +15.4% |
PRA PRAX Praxis Precision Medicines, Inc. | $7.6B | — | -25.7% | — | Buy | +61.1% |
VRT VRTX Vertex Pharmaceuticals Incorporated | $108.8B | 22.3x | +8.1% | 35.4% | Buy | +29.1% |
This peer comparison reflects companies with similar business models, product lines, or market positioning, supplemented by industry grouping when direct matches are limited.
BBIO returns 0.4% annually — null% through dividends and 0.4% through buybacks.
Yield, cadence, and growth quality
How much per-share support comes from repurchases
Common questions answered from live analyst data and company financials.
BridgeBio Pharma, Inc. (BBIO) is rated Buy by Wall Street analysts as of 2026. Of 26 analysts covering the stock, 25 rate it Buy or Strong Buy, 1 rate it Hold, and 0 rate it Sell or Strong Sell. The consensus 12-month price target is $101, implying +47.7% from the current price of $68.
The Wall Street consensus price target for BBIO is $101 based on 26 analyst estimates. The high-end target is $157 (+130.6% from today), and the low-end target is $83 (+21.9%).
Forward earnings data for BBIO is not currently available. Review the valuation table above for trailing P/E, EV/EBITDA, and price-to-sales comparisons against market and sector benchmarks.
The primary risks for BBIO in 2026 are: (1) Pipeline Uncertainty — BridgeBio Pharma relies heavily on a pipeline of drug candidates, with no currently approved products on the market. (2) Financial Weakness — The company's financial strength is rated poorly, posing a potential risk for investors. (3) Insider Selling Activity — Significant insider selling has been observed, with insiders selling approximately $27. Each factor has the potential to pressure earnings or compress the stock's valuation multiple.
Analyst consensus estimates BBIO will report consensus revenue of $775M (+54.3% year-over-year) and EPS of $-1.73 (+53.1% year-over-year) for the upcoming fiscal year. The following year, analysts project $1.1B in revenue.
A confirmed upcoming earnings date for BBIO is not yet available. Check the Earnings section above for the most recent quarterly report dates and forward estimates.
BridgeBio Pharma, Inc. (BBIO) had a free cash outflow of $458M in free cash flow over the trailing twelve months — a free cash flow margin of 91.1%. BBIO returns capital to shareholders through and share repurchases ($48M TTM).