Ranked by reported Q2 2026 13F market value
Share of total reported institutional value in BCRX held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | BlackRock, Inc. | 23.9M | $238.9M | +5.5% | 9.401% | 0.00% |
| 2 | RA CAPITAL MANAGEMENT, L.P. | 15.8M | $158.3M | 0.0% | 6.227% | 1.38% |
| 3 | STATE STREET CORP | 15.2M | $151.9M | +24.4% | 5.977% | 0.00% |
| 4 | DEERFIELD MANAGEMENT COMPANY, L.P. | 15.1M | $151.0M | +0.4% | 5.940% | 1.57% |
| 5 | VANGUARD CAPITAL MANAGEMENT LLC | 11.4M | $113.6M | +2.1% | 4.471% | 0.00% |
| 6 | VANGUARD PORTFOLIO MANAGEMENT LLC | 11.1M | $111.4M | -0.9% | 4.383% | 0.01% |
| 7 | TCG Crossover Management, LLC | 11.0M | $110.2M | 0.0% | 4.336% | 2.65% |
| 8 | PERCEPTIVE ADVISORS LLC | 10.3M | $103.1M | +38.7% | 4.056% | 1.55% |
| 9 | Jupiter Topco LLC | 9.5M | $95.3M | β | 3.754% | 0.04% |
| 10 | Vestal Point Capital, LP | 8.3M | $83.0M | +18.1% | 3.266% | 1.94% |
| 11 | TWO SIGMA INVESTMENTS, LP | 6.8M | $67.8M | +6.0% | 2.666% | 0.05% |
| 12 | GEODE CAPITAL MANAGEMENT, LLC | 6.2M | $62.5M | +8.1% | 2.458% | 0.00% |
| 13 | Aberdeen Group plc | 5.3M | $53.1M | +5.4% | 2.090% | 0.07% |
| 14 | UBS Group AG | 5.1M | $50.8M | +2.7% | 1.998% | 0.01% |
| 15 | BANK OF AMERICA CORP /DE/ | 4.8M | $48.0M | -5.7% | 1.889% | 0.00% |
| 16 | GOLDMAN SACHS GROUP INC | 4.5M | $44.8M | +90.9% | 1.763% | 0.00% |
| 17 | Frazier Life Sciences Management, L.P. | 4.0M | $40.1M | 0.0% | 1.577% | 0.87% |
| 18 | Nuveen, LLC | 4.0M | $40.1M | +4.9% | 1.577% | 0.01% |
| 19 | JANE STREET GROUP, LLC | 3.8M | $38.2M | +212.0% | 1.501% | 0.00% |
| 20 | MILLENNIUM MANAGEMENT LLC | 3.4M | $33.9M | +968.5% | 1.336% | 0.01% |
| 21 | DIMENSIONAL FUND ADVISORS LP | 2.7M | $27.2M | +1.1% | 1.070% | 0.00% |
| 22 | Fisher Asset Management, LLC | 2.6M | $26.0M | -4.7% | 1.024% | 0.01% |
| 23 | RENAISSANCE TECHNOLOGIES LLC | 2.5M | $25.3M | +225.7% | 0.996% | 0.03% |
| 24 | Kynam Capital Management, LP | 2.5M | $25.2M | -55.6% | 0.992% | 1.39% |
| 25 | Candriam S.C.A. | 2.5M | $25.1M | +10.0% | 0.989% | 0.11% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in BCRX β a direct measure of their conviction.
Filings activity in BCRX during Q2 2026, grouped by how each filer changed its position.
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q2 2026 | 317 | +6.0% | 103.79% | +4.72 pp | $2.59B | +11% |
| Q1 2026 | 299 | +11% | 99.07% | 0.03 pp | $2.33B | +45% |
| Q4 2025 | 270 | 3.2% | 99.10% | +6.04 pp | $1.60B | +11% |
| Q3 2025 | 279 | 2.8% | 93.06% | +0.20 pp | $1.45B | 14% |
| Q2 2025 | 287 | +7.1% | 92.86% | +9.75 pp | $1.68B | +33% |
| Q1 2025 | 268 | +7.2% | 83.11% | +2.49 pp | $1.26B | +3.2% |
| Q4 2024 | 250 | 0.4% | 80.62% | 2.39 pp | $1.22B | 1.7% |
| Q3 2024 | 251 | β | 83.01% | β | $1.24B | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying BCRX stock.
Based on Q2 2026 13F filings, institutional ownership of BioCryst Pharmaceuticals, Inc. stands at 103.8%, held across 317 reporting institutions.
BlackRock, Inc. is the largest reported institutional holder of BCRX, with approximately 23,893,036 shares worth $0.24B as of Q2 2026.
Yes β 5 widely-followed marquee investors appear among the top 25 institutional holders of BCRX, including TWO SIGMA INVESTMENTS, LP, JANE STREET GROUP, LLC, MILLENNIUM MANAGEMENT LLC, Fisher Asset Management, LLC, RENAISSANCE TECHNOLOGIES LLC.
Our composite Smart Money Score for BCRX is 80 out of 100 (Strong Smart Money). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
51 institutions opened new positions in BCRX during Q2 2026, while 36 fully exited. 186 added to existing positions and 71 trimmed.
BCRX institutional ownership rose by 4.72 percentage points quarter-over-quarter, with a net change of +18 holders.
The top 10 institutions account for 50.9% of all reported 13F value in BCRX, and the top 25 account for 74.4%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
BioCryst Pharmaceuticals, Inc. (BCRX) Institutional Ownership