Last 48 quarters of trend data · Healthcare · Medical - Diagnostics & Research
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
CareDx, Inc's quarterly P/E stands at 86.8x.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | -53.60 | 86.80 | — | 116.51 | — | — | 3.54 | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/S Ratio | 2.92 | 1.96 | 2.22 | 1.95 | 3.06 | 2.90 | 3.60 | 4.98 | 2.20 | 1.90 | 2.41 | 1.41 | 1.63 |
| — | -32.3% | -38.3% | -60.8% | +39.4% | +52.5% | +49.2% | +253.2% | +34.9% | +19.7% | +30.2% | -50.8% | -54.1% | |
| P/B Ratio | 3.77 | 2.94 | 3.18 | 2.51 | 3.24 | 2.59 | 3.29 | 6.05 | 3.06 | 2.14 | 2.42 | 0.96 | 1.13 |
| — | +13.8% | -3.5% | -58.5% | +5.8% | +21.0% | +36.0% | +528.4% | +171.2% | +83.0% | +70.8% | -53.8% | -56.2% | |
| P/FCF | 30.66 | 448.61 | 12.20 | 5.42 | 29.85 | — | 15.30 | 38.11 | 11.81 | — | — | — | — |
| — | — | -20.2% | -85.8% | +152.7% | — | — | — | — | — | — | — | — | |
| EV / EBITDA | — | 179.94 | — | 25.00 | — | — | 3.65 | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBIT | — | — | — | 89.16 | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
CareDx, Inc's operating margin was 1.0% in Q1 2026, up 6.4 pp QoQ and up 16.8 pp YoY. The trailing four-quarter average of -3.8% lags the current quarter, suggesting the recent improvement is above-trend.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 67.0% | — | 66.6% | 68.7% | 66.9% | 66.4% | 67.5% | 66.7% | 69.7% | 64.0% | 60.9% | 63.5% | 63.2% |
| — | — | -1.2% | +3.0% | -3.9% | +3.8% | +10.7% | +5.1% | +10.3% | -3.6% | -5.1% | -1.3% | -4.1% | |
| Operating Margin | -5.5% | 1.0% | -5.4% | 2.0% | -12.8% | -15.8% | 86.3% | -12.7% | -7.9% | -26.8% | -187.0% | -42.8% | -39.3% |
| — | +106.4% | -106.3% | +115.9% | -61.6% | +41.2% | +146.1% | +70.4% | +79.8% | +14.8% | -705.9% | -96.1% | -45.9% | |
| Net Margin | -5.6% | 2.4% | -3.8% | 1.7% | -9.9% | -12.2% | 90.1% | -8.9% | -5.0% | -23.1% | -180.1% | -35.0% | -35.5% |
| — | +119.5% | -104.2% | +118.7% | -97.3% | +47.1% | +150.0% | +74.4% | +85.9% | +24.8% | -709.5% | -63.7% | -31.9% |
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -6.3% | 0.9% | -1.3% | 0.5% | -2.4% | -2.7% | 23.9% | -2.8% | -1.8% | -6.4% | -36.0% | -5.9% | -6.0% |
| — | +133.3% | -105.6% | +119.1% | -36.6% | +57.6% | +166.4% | +53.1% | +70.6% | -15.3% | -752.8% | -52.7% | -25.6% | |
| ROA | -4.7% | 0.7% | -1.0% | 0.4% | -1.8% | -2.1% | 16.1% | -1.6% | -1.0% | -3.6% | -24.4% | -4.6% | -4.8% |
| — | +132.3% | -106.0% | +124.3% | -82.4% | +41.7% | +166.1% | +66.0% | +79.0% | +18.3% | -623.9% | -48.2% | -20.0% | |
| ROIC | -5.7% | 0.4% | -1.7% | 0.6% | -2.7% | -3.3% | 22.4% | -3.9% | -2.8% | -7.1% | -32.5% | -6.1% | -5.6% |
| — | +110.7% | -107.8% | +114.6% | +1.3% | +53.8% | +169.0% | +36.8% | +50.7% | -48.2% | -775.6% | -61.8% | -3.9% |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
CareDx, Inc's Debt/EBITDA ratio is 14.9x — elevated, raising questions about debt serviceability. The current ratio has weakened 17.1% YoY to 3.40x, tightening the short-term liquidity position. Debt/Equity has declined for 3 consecutive quarters, reflecting a deleveraging trend.
| Metric | TTM | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.06 | 0.06 | 0.06 | 0.09 | 0.09 | 0.08 | 0.07 | 0.11 | 0.12 | 0.13 | 0.13 | 0.09 | 0.09 |
| — | -28.7% | -13.4% | -19.0% | -25.1% | -37.9% | -42.8% | +22.8% | +32.3% | +43.1% | +44.7% | -2.3% | +109.1% | |
| Debt / EBITDA | — | 14.89 | — | 3.85 | — | — | 0.36 | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Current Ratio | 2.86 | 3.40 | 2.86 | 3.03 | 3.30 | 4.11 | 3.94 | 4.10 | 4.09 | 4.32 | 4.02 | 4.75 | 4.84 |
| — | -17.1% | -27.3% | -26.1% | -19.4% | -4.9% | -2.0% | -13.6% | -15.5% | -16.5% | -21.3% | -14.0% | -5.9% | |
| Quick Ratio | 2.56 | 3.07 | 2.56 | 2.75 | 3.00 | 3.84 | 3.72 | 3.87 | 3.85 | 4.03 | 3.77 | 4.50 | 4.59 |
| — | -20.0% | -31.0% | -29.0% | -22.1% | -4.8% | -1.3% | -14.1% | -16.2% | -18.1% | -22.3% | -14.5% | -6.5% | |
| Interest Coverage | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — |
Includes 30+ ratios · 48 years · Updated daily
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CareDx, Inc's current P/E is -53.6x. The average P/E over the last 2 quarters is 101.7x. Quarterly P/E ratios can vary due to seasonal revenue patterns and one-time charges.
CareDx, Inc's current operating margin is -5.5%. Margins have been expanding over recent quarters. Quarterly margins are particularly useful for identifying trend inflections that annual data smooths over.
Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking CareDx, Inc's business trajectory between earnings reports.