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ENSCEnsysce Biosciences, Inc.
$0.30$2M
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HomeStocksENSCFinancials

Ensysce Biosciences, Inc. (ENSC) Financials

9Y historyFree accessUpdated daily

Revenue volatility remains extreme, with quarterly figures fluctuating between zero and $3.4 million, while the lack of a stable gross margin is evidenced by the 2025Q3 negative 5.0% margin.

ENSC Income Statement

Income StatementBalance SheetCash FlowRatios
AnnualQuarterly
MetricTTMDec'25Dec'24Dec'23Dec'22Dec'21Dec'20Dec'19Dec'18Dec'17
Sales/Revenue2.83M5.07M5.21M2.23M2.52M3.53M3.93M1.76M00
Revenue Growth %-54.6%-2.75%133.53%-11.59%-28.54%-10.18%122.86%---
Cost of Goods Sold4.88M07.22M7.59M19.84M1512013.4M1.56M0
COGS % of Revenue--138.56%340.07%786.08%0%0.01%192.88%--
Gross Profit-2.06M0-2.01M-5.36M-17.31M3.53M3.93M-1.64M-1.56M0
Gross Margin %-72.88%--38.57%-240.12%-686.08%100%99.99%-92.88%--
Gross Profit Growth %-100%62.49%69.06%-590.29%-10.17%339.94%-5.09%--
Operating Expenses9.78M10.24M4.72M5.36M6.91M23.4M5.54M6.93M-600K146.69K
OpEx % of Revenue-202.12%90.61%240.3%273.82%662.71%141.03%392.86%--
Selling, General & Admin4.71M4.93M4.72M5.36M6.91M18.71M1.15M6.93M0146.69K
SG&A % of Revenue-97.32%90.61%240.3%273.82%529.89%29.37%392.86%--
Research & Development11.84M10.38M7.22M7.59M19.84M4.69M4.39M3.4M00
R&D % of Revenue-204.81%138.56%340.07%786.08%132.82%111.66%192.88%--
Other Operating Expenses-3M-5.07M-7.22M-7.59M-19.84M00-3.4M00
Operating Income-11.84M-10.24M-6.73M-10.72M-24.22M-19.87M-1.61M-8.57M-959K-147K
Operating Margin %-418.88%-202.12%-129.17%-480.41%-959.91%-562.71%-41.04%-485.74%--
Operating Income Growth %--52.17%37.21%55.75%-21.9%-1131.67%81.17%-793.46%-552.38%-
EBITDA-6.32M-10.23M-6.73M-10.72M-24.22M-19.87M-1.61M-8.57M2.68M-27.55K
EBITDA Margin %-223.84%-202%-129.17%-480.41%-959.9%-562.71%-41.03%-485.73%--
EBITDA Growth %-395.61%-52.07%37.21%55.75%-21.9%-1131.82%81.17%-420.18%9811.49%-
D&A (Non-Cash Add-back)5.49M6.53K4-315115120120100
EBIT-11.8M-10.16M-6.73M-10.72M-24.22M-25.93M834.62K-8.57M2.68M-27.55K
Net Interest Income-18.83K-18.77K-1.29M-354K1.14M1.92M-276K4.25M00
Interest Income00001.25M3.21M719.65K4.25M3.63M0
Interest Expense18.83K18.77K1.29M353.94K109.53K1.29M995.5K000
Other Income/Expense48.64K64.76K-1.26M91.91K14.41K-9.28M1.45M-1.53M3.63M119.14K
Pretax Income-11.79M-10.18M-7.99M-10.63M-24.21M-29.15M-160.88K-10.1M2.68M-27.56K
Pretax Margin %-417.16%-200.85%-153.3%-476.29%-959.33%-825.38%-4.09%-572.7%--
Income Tax00000000553.92K3.63K
Effective Tax Rate %0%0%0%0%0%0%0%0%20.7%-13.19%
Net Income-11.79M-10.18M-7.99M-10.61M-24.17M-29.08M56.77K-10.1M-1.34M-31.19K
Net Margin %-417.14%-200.84%-153.3%-475.71%-957.93%-823.62%1.44%-572.7%--
Net Income Growth %-72.91%-27.4%24.74%56.09%16.89%-51330.78%100.56%-652.22%-4205.45%-
Net Income (Continuing)-11.79M-10.18M-7.99M-10.63M-24.21M-29.15M-160.88K-10.1M2.12M-31.19K
Discontinued Operations0000000000
Minority Interest-328.97K-328.97B-328.48K-328.41K-315.21K-279.81K-217.63K000
EPS (Diluted)-1.72-3.98-4.57-4.69-139.44-355.680.560.24-0.22-0.01
EPS Growth %36.79%12.91%2.56%96.64%60.8%-63614.29%133.33%209.09%--
EPS (Basic)--3.98-4.57-4.69-139.44-355.680.560.24-0.22-0.01
Diluted Shares Outstanding6.84M25.57M1.75M2.26M179.93K84.02K6.37M6.09M6.01M5.98M
Basic Shares Outstanding6.84M2.56M1.75M2.26M179.93K84.02K4.46M6.09M6.01M5.98M
Dividend Payout Ratio----------

Key Metrics

Growth RegimeMixed
ProfitabilityNegative
Balance SheetVulnerable
Cash FlowBurning
Top Statement Risk

Imminent liquidity and dilution

Verified Source

Metrics are mathematically derived from official filings.

SEC 10-K (2026Q1)

Grant-Dependent Revenue Volatility Persists

As reported in recent financial filings, Ensysce Biosciences exhibits highly erratic revenue patterns, with quarterly figures fluctuating between zero and $3.4 million, reflecting a total reliance on non-recurring federal research grants rather than any sustainable commercial product sales or predictable market-driven demand for its pipeline assets.

The absence of a consistent revenue base suggests that the company remains in a pre-commercial state where top-line performance is dictated by the timing of research milestones. Investors should interpret these figures as non-dilutive funding offsets rather than indicators of future commercial scalability or market penetration.

Clinical Trial Driven Expense Burn

Based on the company's historical income statements, R&D spending remains the primary driver of the cost structure, frequently exceeding $3 million per quarter, which underscores the significant capital intensity required to advance the TAAP platform through late-stage clinical trials without a commercial revenue buffer.

The high fixed-cost nature of these clinical programs implies that the company lacks operational flexibility, as expenses are tied to patient enrollment and regulatory milestones. This cost profile warrants close monitoring, as any delay in trial execution could exacerbate the existing cash burn without providing the necessary data readouts to justify further investment.

Structural Absence of Gross Profit

According to the provided income statement data, the company lacks a stable gross margin, with figures oscillating wildly between positive territory and deep negative values, confirming that the firm has not yet established a viable manufacturing or commercial supply chain for its prodrug technology.

The lack of a consistent gross margin is a fundamental characteristic of a clinical-stage entity that has yet to transition to product sales. Analysts should view the current margin volatility as a reflection of accounting adjustments related to grant-funded research rather than an indication of future pricing power or production efficiency.

Liquidity Constraints Threaten Operational Continuity

As indicated by the most recent financial disclosures, the company's cash position of approximately $3.5 million appears insufficient to sustain current R&D burn rates for more than a year, suggesting that the firm faces a high probability of significant equity dilution or potential insolvency risks.

The reliance on external financing to bridge the gap between grant funding and clinical progress creates a precarious situation for shareholders. Investors should consider whether the current valuation adequately accounts for the high likelihood of future capital raises, which may be necessary to maintain the development of the PF614-MPAR platform.

ENSC — Frequently Asked Questions

Quick answers to the most common questions about buying ENSC stock.

What was Ensysce Biosciences, Inc.'s (ENSC) revenue in 2025?

For fiscal year 2025, Ensysce Biosciences, Inc. (ENSC) reported total revenue of $5.1M.

Is Ensysce Biosciences, Inc. (ENSC) profitable?

Ensysce Biosciences, Inc. (ENSC) reported a net loss of $10.2M for the fiscal year ending 2025.

What is Ensysce Biosciences, Inc.'s operating profit margin?

Ensysce Biosciences, Inc. (ENSC) reported an operating income of $-10.2M, resulting in an operating profit margin of -202.1%. This margin reflects the operational efficiency of the business before interest and taxes.