Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in ETON held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | Opaleye Management Inc. | 2.9M | $70.6M | 0.0% | 10.441% | 9.30% |
| 2 | EcoR1 Capital, LLC | 2.2M | $53.6M | +7.0% | 7.929% | 2.27% |
| 3 | BlackRock, Inc. | 1.7M | $42.4M | -1.2% | 6.269% | 0.00% |
| 4 | Nantahala Capital Management, LLC | 1.2M | $29.0M | 0.0% | 4.293% | 1.49% |
| 5 | VANGUARD CAPITAL MANAGEMENT LLC | 994K | $24.5M | β | 3.629% | 0.00% |
| 6 | GEODE CAPITAL MANAGEMENT, LLC | 578K | $14.3M | +2.2% | 2.109% | 0.00% |
| 7 | STATE STREET CORP | 530K | $13.1M | +5.6% | 1.936% | 0.00% |
| 8 | MORGAN STANLEY | 478K | $11.8M | -3.2% | 1.745% | 0.00% |
| 9 | Westside Investment Management, Inc. | 468K | $11.5M | -0.6% | 1.708% | 1.77% |
| 10 | OBERWEIS ASSET MANAGEMENT INC/ | 439K | $10.8M | +1.8% | 1.604% | 0.32% |
| 11 | Pillsbury Lake Capital LLC | 365K | $9.0M | β | 1.332% | 4.08% |
| 12 | CANNELL CAPITAL LLC | 342K | $8.4M | +57.7% | 1.248% | 5.32% |
| 13 | BNP PARIBAS ARBITRAGE, SA | 302K | $7.5M | +8.9% | 1.103% | 0.00% |
| 14 | NORTHERN TRUST CORP | 238K | $5.9M | +2.6% | 0.868% | 0.00% |
| 15 | GOLDMAN SACHS GROUP INC | 217K | $5.4M | +10.8% | 0.794% | 0.00% |
| 16 | PRELUDE CAPITAL MANAGEMENT, LLC | 189K | $4.7M | +316.6% | 0.689% | 0.36% |
| 17 | Aristides Capital LLC | 186K | $4.6M | +15.2% | 0.679% | 1.52% |
| 18 | Panoramic Capital, LLC | 185K | $4.6M | β | 0.675% | 3.21% |
| 19 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 180K | $4.4M | β | 0.656% | 0.00% |
| 20 | Lumbard & Kellner, LLC | 176K | $4.3M | +0.5% | 0.642% | 1.50% |
| 21 | Woodline Partners LP | 171K | $4.2M | +78.8% | 0.623% | 0.02% |
| 22 | UBS Group AG | 169K | $4.2M | +33.4% | 0.617% | 0.00% |
| 23 | Soleus Capital Management, L.P. | 166K | $4.1M | β | 0.607% | 0.17% |
| 24 | VANGUARD FIDUCIARY TRUST CO | 165K | $4.1M | β | 0.601% | 0.00% |
| 25 | RENAISSANCE TECHNOLOGIES LLC | 163K | $4.0M | -20.6% | 0.596% | 0.01% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in ETON β a direct measure of their conviction.
Filings activity in ETON during Q1 2026, grouped by how each filer changed its position.
Institutions that opened a new ETON position in Q1 2026
Institutions that fully closed their ETON position in Q1 2026
8 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 114 | +12% | 48.09% | +17.95 pp | $416M | +60% |
| Q4 2025 | 102 | +1.0% | 30.14% | 13.28 pp | $261M | 31% |
| Q3 2025 | 101 | +19% | 43.42% | +17.21 pp | $376M | +66% |
| Q2 2025 | 85 | +0.0% | 26.21% | +6.03 pp | $227M | +30% |
| Q1 2025 | 85 | +20% | 20.18% | +0.31 pp | $175M | +1.6% |
| Q4 2024 | 71 | +48% | 19.87% | +13.26 pp | $172M | +201% |
| Q3 2024 | 48 | +9.1% | 6.61% | +3.57 pp | $57M | +117% |
| Q2 2024 | 44 | β | 3.04% | β | $26M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying ETON stock.
Based on Q1 2026 13F filings, institutional ownership of Eton Pharmaceuticals, Inc. stands at 48.1%, held across 114 reporting institutions.
Opaleye Management Inc. is the largest reported institutional holder of ETON, with approximately 2,860,000 shares worth $0.07B as of Q1 2026.
Yes β 2 widely-followed marquee investors appear among the top 25 institutional holders of ETON, including SUSQUEHANNA INTERNATIONAL GROUP, LLP, RENAISSANCE TECHNOLOGIES LLC.
Our composite Smart Money Score for ETON is 68 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
33 institutions opened new positions in ETON during Q1 2026, while 21 fully exited. 69 added to existing positions and 10 trimmed.
ETON institutional ownership rose by 17.95 percentage points quarter-over-quarter, with a net change of +12 holders.
The top 10 institutions account for 67.7% of all reported 13F value in ETON, and the top 25 account for 86.7%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Eton Pharmaceuticals, Inc. (ETON) Institutional Ownership