Eton Pharmaceuticals, Inc. (ETON) P/E Ratio History
Deep ValueTrading at -339.3x · 0th percentile of 5-year range · Significant discount to historical valuation · Data 2023–2026
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P/E Ratio Analysis
As of September 26, 2026, Eton Pharmaceuticals, Inc. (ETON) trades at a price-to-earnings ratio of -339.3x, with a stock price of $57.68 and trailing twelve-month earnings per share of $0.39.
The current P/E is 525% below its 5-year average of 79.8x. Over the past five years, ETON's P/E has ranged from a low of 47.7x to a high of 97.7x, placing the current valuation at the 0th percentile of its historical range.
Compared to the Healthcare sector median P/E of 23.6x, ETON trades at a 1540% discount to its sector peers. The sector includes 225 companies with P/E ratios ranging from 0.0x to 167.0x.
Relative to the broader market, ETON trades at a notable discount to the S&P 500 median P/E of 25.0x. Investors should consider the company's growth prospects, competitive position, and earnings quality when evaluating whether the current valuation is justified.
For a comprehensive intrinsic value estimate using discounted cash flow analysis, see our ETON DCF Valuation Calculator →
Note: P/E ratio is just one valuation metric. It does not account for balance sheet strength, cash flow quality, or growth sustainability. Always conduct comprehensive due diligence before making investment decisions.
ETON Cross-Benchmark Valuation
How does the current P/E compare to sector peers and the broader market?
ETON P/E vs Peers
Commercial Rare Disease Biopharma peers sorted by market cap
| Company | Market Cap | P/E Ratio | PEG Ratio | EPS Growth (1Y) |
|---|---|---|---|---|
| $6B | 29.2 | - | -22% | |
| $12B | 141.6 | - | -33% | |
| $1B | 28.9Lowest | 3.87Best | +1883%Best |
Lower P/E can signal a discount or weaker growth expectations; PEG adds growth context.
ETON Historical P/E Data (2023–2026)
Quarterly P/E ratios calculated from closing price and TTM EPS
| Quarter | Period End | Price | TTM EPS | P/E Ratio | vs Avg |
|---|---|---|---|---|---|
| FY2026 Q2 | - | $36.20 | $0.38 | 94.1x | +18% |
| FY2024 Q1 | Mar 31 2024 | $3.75 | $0.04 | 97.7x | +22% |
| FY2023 Q3 | Sep 30 2023 | $4.17 | $0.09 | 47.7x | -40% |
Average P/E for displayed period: 79.8x
ETON Chart Terminal
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Intrinsic Valuation
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Historical Returns
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Peer Comparison
Compare growth, multiples, and margins vs sector.
ETON — Frequently Asked Questions
Quick answers to the most common questions about buying ETON stock.
What is ETON's P/E ratio?
Eton Pharmaceuticals, Inc. (ETON) trailing twelve-month P/E ratio is -339.3x, based on TTM diluted EPS of $0.39. The 5-year average P/E is 79.8x and the historical range spans 47.7x to 97.7x.
Is ETON stock overvalued or undervalued?
ETON trades at -339.3x P/E, below its 5-year average of 79.8x. At the 0th percentile of its historical range (47.7x–97.7x), the stock is priced at a discount to its own history.
Is ETON stock expensive?
No, ETON is not expensive on a historical basis. The current P/E of -339.3x is below the 5-year average of 79.8x and sits at the 0th percentile of its valuation range.
What is ETON's historical P/E range?
Over the past 5 years, ETON's P/E ratio has ranged from 47.7x to 97.7x, with a median of 94.1x and an average of 79.8x. The current P/E of -339.3x places the stock at the 0th percentile of this range. Full historical data spans 2023–2026.
How does ETON's P/E compare to the S&P 500?
ETON trades at -339.3x P/E versus the S&P 500 median of 25.0x. The 1457% discount to the market suggests lower growth expectations or perceived higher risk.
How does ETON's valuation compare to Healthcare peers?
Eton Pharmaceuticals, Inc. P/E of -339.3x compares to the Healthcare sector median of 23.6x. The discount suggests lower growth expectations, weaker margins, or higher perceived risk relative to peers. See the peer comparison table on this page for ticker-by-ticker P/E and PEG.
What is ETON's PEG ratio?
ETON PEG ratio is N/A, based on a P/E of -339.3x and EPS growth of -13.3%. PEG normalises P/E by growth and helps compare stocks with different earnings trajectories.
What is ETON's earnings yield?
ETON earnings yield is N/A, the inverse of its -339.3x P/E ratio. Earnings yield represents the percentage of each dollar invested that the company earns. It can be compared directly to bond yields to assess relative attractiveness of stocks versus fixed income.