27 years of historical data (1999–2025) · Healthcare · Medical - Diagnostics & Research
Percentile shows where the current value sits in 30-year historical distribution. Sparklines show 5-year trend.
Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow
Exact Sciences Corporation currently has a negative P/E ratio, indicating the company is operating at a loss on a trailing-twelve-month basis. On a free-cash-flow basis, the stock trades at 56.1x P/FCF, 72% below the 5-year average of 203.3x.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Market Cap | $20.0B | $19.2B | $10.4B | $13.3B | $8.7B | $13.3B | $20.0B | $12.1B | $7.7B | $6.1B | $1.4B |
| Enterprise Value | $21.6B | $20.7B | $12.5B | $15.3B | $10.9B | $15.4B | $20.9B | $12.9B | $8.2B | $6.0B | $1.3B |
| P/E Ratio → | -95.37 | — | — | — | — | — | — | — | — | — | — |
| P/S Ratio | 6.16 | 5.90 | 3.75 | 5.33 | 4.19 | 7.55 | 13.43 | 13.85 | 16.97 | 22.85 | 13.76 |
| P/B Ratio | 8.24 | 7.98 | 4.31 | 4.24 | 2.87 | 3.94 | 8.96 | 5.31 | 11.32 | 11.68 | 4.08 |
| P/FCF | 56.10 | 53.71 | 138.84 | 417.40 | — | — | 277.61 | — | — | — | — |
| P/OCF | 40.73 | 38.99 | 49.16 | 85.36 | — | — | 146.72 | — | — | — | — |
P/E links to full P/E history page with 30-year chart
Enterprise-value multiples — capital-structure-neutral measures of total business value
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| EV / Revenue | — | 6.38 | 4.53 | 6.11 | 5.25 | 8.72 | 13.99 | 14.74 | 18.13 | 22.58 | 13.32 |
| EV / EBITDA | — | — | — | — | — | — | — | — | — | — | — |
| EV / EBIT | — | — | — | — | — | — | — | — | — | — | — |
| EV / FCF | — | 58.10 | 167.73 | 478.45 | — | — | 289.25 | — | — | — | — |
Margins and return-on-capital ratios measuring operating efficiency
Exact Sciences Corporation earns an operating margin of -6.4%. Operating margins have expanded from -8.6% to -6.4% over the past 3 years, signaling improving operational efficiency. A negative ROE of -8.7% indicates the company is currently destroying shareholder equity.
Full margin charts and quarterly trend are on the Earnings History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 69.7% | 69.7% | 69.5% | 70.5% | 68.3% | 74.0% | 76.2% | 75.3% | 74.0% | 70.2% | 54.5% |
| Operating Margin | -6.4% | -6.4% | -38.0% | -8.6% | -28.5% | -48.4% | -51.5% | -26.7% | -35.1% | -44.5% | -170.1% |
| Net Profit Margin | -6.4% | -6.4% | -37.3% | -8.2% | -29.9% | -33.7% | -55.2% | -24.3% | -38.5% | -43.0% | -168.3% |
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -8.7% | -8.7% | -37.1% | -6.6% | -19.4% | -21.2% | -36.4% | -14.4% | -29.2% | -26.7% | -50.5% |
| ROA | -3.5% | -3.5% | -16.6% | -3.2% | -9.7% | -10.3% | -19.5% | -8.5% | -16.5% | -23.5% | -45.1% |
| ROIC | -3.6% | -3.6% | -16.3% | -3.1% | -8.3% | -15.0% | -18.8% | -8.2% | -14.4% | -24.0% | -43.4% |
| ROCE | -4.0% | -4.0% | -18.8% | -3.7% | -9.9% | -16.4% | -20.3% | -10.0% | -16.6% | -27.0% | -49.4% |
Solvency and debt-coverage ratios — lower is generally safer
Net debt stands at $1.6B ($2.5B total debt minus $956M cash).
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 1.05 | 1.05 | 1.15 | 0.81 | 0.80 | 0.70 | 1.04 | 0.42 | 1.01 | 0.01 | 0.02 |
| Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — |
| Net Debt / Equity | — | 0.65 | 0.90 | 0.62 | 0.72 | 0.61 | 0.38 | 0.34 | 0.78 | -0.14 | -0.13 |
| Net Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — |
| Debt / FCF | — | 4.39 | 28.89 | 61.05 | — | — | 11.64 | — | — | — | — |
| Interest Coverage | — | — | -32.80 | -8.80 | -42.68 | -66.44 | -44.84 | -4.58 | -4.33 | -574.32 | -793.50 |
Short-term solvency ratios and asset-utilisation metrics
Exact Sciences Corporation's current ratio of 2.43x is well above the 1.0 safety threshold, indicating strong short-term liquidity with ample room to cover current liabilities. The current ratio has improved from 2.32x to 2.43x over the past 3 years.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 2.43 | 2.43 | 2.15 | 2.32 | 2.38 | 2.76 | 3.47 | 2.34 | 8.99 | 7.15 | 10.87 |
| Quick Ratio | 2.17 | 2.17 | 1.92 | 2.07 | 2.09 | 2.56 | 3.33 | 2.08 | 8.70 | 6.77 | 10.65 |
| Cash Ratio | 1.50 | 1.50 | 1.42 | 1.51 | 1.53 | 1.99 | 2.91 | 1.37 | 8.23 | 6.23 | 10.14 |
| Asset Turnover | — | 0.55 | 0.47 | 0.39 | 0.33 | 0.26 | 0.30 | 0.25 | 0.30 | 0.44 | 0.26 |
| Inventory Turnover | 5.92 | 5.92 | 5.17 | 5.79 | 5.59 | 4.37 | 3.84 | 3.51 | 3.01 | 3.04 | 6.61 |
| Days Sales Outstanding | — | 33.57 | 32.94 | 29.73 | 27.68 | 44.75 | 57.07 | 54.30 | 36.41 | 36.25 | 31.32 |
Earnings, FCF, buyback, and dividend yields — total returns to shareholders
Exact Sciences Corporation returns 0.1% to shareholders annually primarily through share buybacks.
Full dividend history and growth charts are on the Dividend History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Dividend Yield | — | — | — | — | — | — | — | — | — | — | — |
| Payout Ratio | — | — | — | — | — | — | — | — | — | — | — |
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Earnings Yield | — | — | — | — | — | — | — | — | — | — | — |
| FCF Yield | 1.8% | 1.9% | 0.7% | 0.2% | — | — | 0.4% | — | — | — | — |
| Buyback Yield | 0.1% | 0.1% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.1% | 0.0% | 0.0% |
| Total Shareholder Yield | 0.1% | 0.1% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.1% | 0.0% | 0.0% |
| Shares Outstanding | — | $189M | $184M | $180M | $176M | $171M | $151M | $131M | $122M | $116M | $102M |
Compare EXAS with 10 similar companies in its peer group
| Company | Market Cap | P/E | EV/EBITDA | P/FCF | Gross Margin | Op Margin | ROE | ROIC | Debt/EBITDA |
|---|---|---|---|---|---|---|---|---|---|
| $20B | -95.4 | — | 56.1 | 69.7% | -6.4% | -8.7% | -3.6% | — | |
| $12B | -27.8 | — | — | 64.5% | -44.4% | — | -34.9% | — | |
| $31B | -144.6 | — | 285.5 | 64.8% | -13.4% | -14.3% | -36.1% | — | |
| $21B | 25.5 | 19.6 | 22.6 | 66.7% | 19.9% | 33.4% | 16.8% | 2.3 | |
| $21B | 24.7 | 12.7 | 17.6 | 26.8% | 10.9% | 10.5% | 7.8% | 3.3 | |
| $21B | 21.8 | 12.7 | 15.5 | 31.9% | 14.5% | 14.0% | 8.8% | 3.2 | |
| $2B | -1.8 | 20.7 | — | 47.1% | 1.1% | -41.9% | 0.2% | 6.8 | |
| $1B | -53.6 | — | 30.7 | 67.0% | -5.5% | -6.3% | -5.7% | — | |
| $176B | 26.8 | 19.0 | 28.0 | 37.7% | 18.2% | 13.1% | 7.5% | 3.8 | |
| $124B | 34.9 | 18.2 | 23.6 | 60.9% | 20.9% | 7.1% | 5.9% | 2.4 | |
| $7B | 9.2 | 16.7 | 18.5 | 52.0% | 10.5% | 10.8% | 2.6% | 3.2 | |
| Healthcare Median | — | 22.3 | 14.4 | 18.5 | 63.9% | -5.2% | -33.7% | -11.2% | 3.3 |
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Includes 30+ ratios · 27 years · Updated daily
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Exact Sciences Corporation's current P/E ratio is -95.4x. This places it at the 50th percentile of its historical range.
Exact Sciences Corporation's return on equity (ROE) is -8.7%. The historical average is -66.0%.
Based on historical data, Exact Sciences Corporation is trading at a P/E of -95.4x. This is at the 50th percentile of its historical P/E range. Compare with industry peers and growth rates for a complete picture.
Exact Sciences Corporation has 69.7% gross margin and -6.4% operating margin.