8-K Announcements
6Apr 27, 2026·SEC
Feb 24, 2026·SEC
Jan 12, 2026·SEC
Fulcrum Therapeutics, Inc. (FULC) fundamental analysis — strengths, weaknesses & financial health based on data analysis
* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.
Fulcrum Therapeutics, Inc. (FULC) stock price & volume — 10-year historical chart
Fulcrum Therapeutics, Inc. (FULC) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR
Fulcrum Therapeutics, Inc. (FULC) EPS & revenue vs analyst estimates — last 4 quarters
| Quarter | Date | EPS (Act vs Est) | Revenue (Act vs Est) |
|---|---|---|---|
| Q2 2026Latest | Apr 27, 2026 | $0.25vs $0.31+19.4% | — |
| Q1 2026 | Feb 24, 2026 | $0.31vs $0.31+0.0% | — |
| Q4 2025 | Oct 29, 2025 | $0.31vs $0.29-6.9% | — |
| Q3 2025 | Jul 29, 2025 | $0.28vs $0.29+3.4% | — |
Fulcrum Therapeutics, Inc. (FULC) competitors in Commercial Rare Disease Biopharma — business model, growth, and fundamentals comparison
Fulcrum Therapeutics, Inc. (FULC) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.
Fulcrum Therapeutics, Inc. (FULC) annual income statement — 10-year revenue, gross profit & net income history
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 | TTM |
|---|---|---|---|---|---|---|---|---|---|---|
| Sales/Revenue | 0 | 0 | 0 | 8.82M | 19.16M | 6.34M | 2.81M | 80M | 0 | 0 |
| Revenue Growth % | - | - | - | - | 117.19% | -66.91% | -55.77% | 2752.05% | -100% | -100% |
| Cost of Goods Sold | 715K | 1.34M | 2.05M | 59.04M | 69.7M | 76.78M | 0 | 63.39M | 1.39M | 0 |
| COGS % of Revenue | - | - | - | 669.18% | 363.73% | 1210.69% | - | 79.23% | - | - |
| Gross Profit | -715K▲ 0% | -1.34M▼ 88.1% | -2.05M▼ 52.6% | -50.22M▼ 2346.1% | -50.54M▼ 0.6% | -70.44M▼ 39.4% | 2.81M▲ 104.0% | 16.61M▲ 492.3% | -1.39M▼ 108.4% | 0▲ 0% |
| Gross Margin % | - | - | - | -569.18% | -263.73% | -1110.69% | 100% | 20.77% | - | - |
| Gross Profit Growth % | - | -88.11% | -52.64% | -2346.13% | -0.64% | -39.38% | 103.98% | 492.3% | -108.37% | - |
| Operating Expenses | 22.99M | 33.5M | 56.57M | 21.39M | 30.52M | 42.12M | 113.47M | 38.51M | 83.38M | 86.55M |
| OpEx % of Revenue | - | - | - | 242.46% | 159.24% | 664.16% | 4045.24% | 48.14% | - | - |
| Selling, General & Admin | 4.5M | 8.31M | 13.14M | 21.39M | 30.52M | 41.69M | 41.67M | 36.45M | 28.67M | 29.77M |
| SG&A % of Revenue | - | - | - | 242.46% | 159.24% | 657.43% | 1485.49% | 45.56% | - | - |
| Research & Development | 18.49M | 25.18M | 43.43M | 59.04M | 69.7M | 76.78M | 71.8M | 63.39M | 56.1M | 56.78M |
| R&D % of Revenue | - | - | - | 669.18% | 363.73% | 1210.69% | 2559.75% | 79.23% | - | - |
| Other Operating Expenses | 28K | 392K | 0 | -59.04M | -69.7M | -76.36M | 0 | -61.32M | -1.39M | 0 |
| Operating Income | -22.99M▲ 0% | -33.5M▼ 45.7% | -58.63M▼ 75.0% | -71.61M▼ 22.1% | -81.05M▼ 13.2% | -112.56M▼ 38.9% | -110.66M▲ 1.7% | -21.9M▲ 80.2% | -84.77M▼ 287.1% | -86.55M▲ 0% |
| Operating Margin % | - | - | - | -811.64% | -422.97% | -1774.85% | -3945.24% | -27.37% | - | - |
| Operating Income Growth % | - | -45.69% | -75.01% | -22.15% | -13.19% | -38.87% | 1.69% | 80.21% | -287.13% | - |
| EBITDA | -22.28M | -32.15M | -56.57M | -69.23M | -78.54M | -110.15M | -108.49M | -20.3M | -83.38M | -85.52M |
| EBITDA Margin % | - | - | - | -784.68% | -409.85% | -1736.79% | -3867.81% | -25.38% | - | - |
| EBITDA Growth % | - | -44.33% | -75.95% | -22.38% | -13.44% | -40.24% | 1.5% | 81.29% | -310.65% | -677.48% |
| D&A (Non-Cash Add-back) | 715K | 1.34M | 2.05M | 2.38M | 2.52M | 2.41M | 2.17M | 1.59M | 1.39M | 1.04M |
| EBIT | -22.99M | -33.5M | -82.68M | -71.61M | -81.05M | -112.13M | -110.66M | -19.83M | -74.88M | -57.23M |
| Net Interest Income | 0 | 0 | 1.51M | 792K | 207K | 0 | 0 | 0 | 0 | 0 |
| Interest Income | 0 | 0 | 1.51M | 792K | 207K | 0 | 0 | 0 | 0 | 0 |
| Interest Expense | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Income/Expense | 29K | 910K | -24.05M | 792K | 207K | 2.69M | 13.33M | 12.17M | 9.89M | 10.44M |
| Pretax Income | -22.96M▲ 0% | -32.59M▼ 41.9% | -82.68M▼ 153.7% | -70.82M▲ 14.3% | -80.85M▼ 14.2% | -109.87M▼ 35.9% | -97.33M▲ 11.4% | -9.72M▲ 90.0% | -74.88M▼ 670.0% | -76.12M▲ 0% |
| Pretax Margin % | - | - | - | -802.66% | -421.89% | -1732.43% | -3470.05% | -12.16% | - | - |
| Income Tax | -1K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Effective Tax Rate % | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% |
| Net Income | -22.96M▲ 0% | -32.59M▼ 41.9% | -82.68M▼ 153.7% | -70.82M▲ 14.3% | -80.85M▼ 14.2% | -109.87M▼ 35.9% | -97.33M▲ 11.4% | -9.72M▲ 90.0% | -74.88M▼ 670.0% | -76.12M▲ 0% |
| Net Margin % | - | - | - | -802.66% | -421.89% | -1732.43% | -3470.05% | -12.16% | - | - |
| Net Income Growth % | - | -41.91% | -153.7% | 14.34% | -14.16% | -35.9% | 11.41% | 90.01% | -669.97% | -14824.71% |
| Net Income (Continuing) | -22.96M | -32.59M | -82.68M | -70.82M | -80.85M | -109.87M | -97.33M | -9.72M | -74.88M | -76.12M |
| Discontinued Operations | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| EPS (Diluted) | -1.36▲ 0% | -1.92▼ 41.2% | -3.49▼ 81.8% | -2.70▲ 22.6% | -2.22▲ 17.8% | -2.35▼ 5.9% | -1.59▲ 32.3% | -0.16▲ 89.9% | -1.18▼ 637.5% | -1.00▲ 0% |
| EPS Growth % | - | -41.18% | -81.77% | 22.64% | 17.78% | -5.86% | 32.34% | 89.94% | -637.5% | -1542.86% |
| EPS (Basic) | -1.36 | -1.92 | -3.49 | -2.70 | -2.22 | -2.35 | -1.59 | -0.16 | -1.18 | - |
| Diluted Shares Outstanding | 16.94M | 16.94M | 22.66M | 25.35M | 35.36M | 44.99M | 61.31M | 61.98M | 63.35M | 76.22M |
| Basic Shares Outstanding | 16.94M | 16.94M | 22.66M | 25.35M | 35.36M | 44.99M | 61.31M | 61.98M | 63.35M | 76.22M |
| Dividend Payout Ratio | - | - | - | - | - | - | - | - | - | - |
Fulcrum Therapeutics, Inc. (FULC) balance sheet — assets, liabilities & shareholders' equity
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 | TTM |
|---|---|---|---|---|---|---|---|---|---|---|
| Total Current Assets | 1.34M | 74.09M | 100.08M | 112.91M | 226M | 207.52M | 242.2M | 249.92M | 357.48M | 338.67M |
| Cash & Short-Term Investments | 407K | 72.8M | 96.71M | 112.91M | 218.16M | 202.92M | 236.22M | 241.02M | 352.31M | 333.32M |
| Cash Only | 407K | 72.8M | 96.71M | 57.05M | 35.41M | 35.1M | 25.56M | 58.21M | 197.53M | 50.26M |
| Short-Term Investments | 0 | 0 | 0 | 55.86M | 182.75M | 167.82M | 210.66M | 182.81M | 154.77M | 283.06M |
| Accounts Receivable | 39K | 501K | 111K | 2.71M | 4.11M | 1.08M | 2.25M | 3.34M | 1.07M | 0 |
| Days Sales Outstanding | - | - | - | 111.99 | 78.28 | 62.21 | 292.65 | 15.25 | - | - |
| Inventory | 734K | 559K | 2.98M | -2.78M | -473K | 0 | 0 | 0 | 0 | 0 |
| Days Inventory Outstanding | 374.7 | 151.7 | 528.92 | - | - | - | - | - | - | - |
| Other Current Assets | 248K | 238K | 284K | 74K | 0 | 0 | 0 | 0 | 5.17M | 5.35M |
| Total Non-Current Assets | 3M | 11.68M | 10.36M | 16.66M | 9M | 19.17M | 15.49M | 10.79M | 8.8M | 8.1M |
| Property, Plant & Equipment | 2.94M | 10.55M | 87.94M | 8.4M | 7.37M | 15.97M | 12.39M | 9.58M | 7.07M | 6.35M |
| Fixed Asset Turnover | - | - | - | 1.05x | 2.60x | 0.40x | 0.23x | 8.35x | - | 0.00x |
| Goodwill | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Intangible Assets | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Long-Term Investments | 0 | 1.09M | 1.09M | 1.09M | 1.09M | 1.09M | 0 | 0 | 0 | 0 |
| Other Non-Current Assets | 60K | 38K | -78.68M | 7.17M | 542K | 2.1M | 3.1M | 1.21M | 1.74M | 5.91M |
| Total Assets | 4.34M▲ 0% | 85.77M▲ 1876.3% | 110.44M▲ 28.8% | 129.58M▲ 17.3% | 235M▲ 81.4% | 226.69M▼ 3.5% | 257.69M▲ 13.7% | 260.72M▲ 1.2% | 366.28M▲ 40.5% | 346.77M▲ 0% |
| Asset Turnover | - | - | - | 0.07x | 0.08x | 0.03x | 0.01x | 0.31x | - | 0.00x |
| Asset Growth % | - | 1876.29% | 28.76% | 17.33% | 81.36% | -3.54% | 13.68% | 1.17% | 40.49% | 38.18% |
| Total Current Liabilities | 2.79M | 4.23M | 12.14M | 26.73M | 19.2M | 16.73M | 13.68M | 11.04M | 13.05M | 9.86M |
| Accounts Payable | 1.67M | 1.26M | 2.19M | 4.08M | 4.79M | 3.64M | 2.76M | 1.16M | 1.59M | 2.45M |
| Days Payables Outstanding | 854.05 | 342.75 | 388.65 | 25.22 | 25.07 | 17.29 | - | 6.7 | 418.04 | - |
| Short-Term Debt | 0 | 0 | 0 | 0 | 0 | 2.6M | 0 | 0 | 2.4M | 2.46M |
| Deferred Revenue (Current) | 0 | 2.8M | 3.99M | 14.91M | 4.71M | 934K | 0 | 0 | 0 | 0 |
| Other Current Liabilities | 20K | 781K | 3.68M | 4.79M | 4.71M | 5.34M | 396K | 463K | 9.05M | 4.95M |
| Current Ratio | 0.48x | 17.52x | 8.24x | 4.23x | 11.77x | 12.41x | 17.71x | 22.63x | 27.40x | 27.40x |
| Quick Ratio | 0.22x | 17.39x | 8.00x | 4.33x | 11.80x | 12.41x | 17.71x | 22.63x | 27.40x | 27.40x |
| Cash Conversion Cycle | - | - | - | - | - | - | - | - | - | - |
| Total Non-Current Liabilities | 233K | 5.54M | 11.15M | 7.67M | 4.26M | 11.02M | 8.83M | 6.64M | 4.24M | 3.6M |
| Long-Term Debt | 34.59M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.04M | 3.41M |
| Capital Lease Obligations | 0 | 0 | 0 | 0 | 0 | 10.82M | 8.63M | 6.44M | 0 | 9.94M |
| Deferred Tax Liabilities | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Current Liabilities | -34.35M | 5.54M | 5.13M | 4.7M | 4.26M | 0 | 197K | 197K | 197K | 788K |
| Total Liabilities | 3.02M | 9.77M | 23.29M | 34.4M | 23.46M | 27.74M | 22.5M | 17.68M | 17.28M | 13.47M |
| Total Debt | 34.59M | 46K | 50K | 17K | 0 | 13.42M | 10.82M | 8.63M | 6.44M | 5.87M |
| Net Debt | 34.18M | -72.75M | -96.66M | -57.03M | -35.41M | -21.68M | -14.74M | -49.58M | -191.09M | -44.39M |
| Debt / Equity | 26.16x | 0.00x | 0.00x | 0.00x | - | 0.07x | 0.05x | 0.04x | 0.02x | 0.02x |
| Debt / EBITDA | - | - | - | - | - | - | - | - | - | -0.07x |
| Net Debt / EBITDA | - | - | - | - | - | - | - | - | - | 0.52x |
| Interest Coverage | - | - | - | - | - | - | - | - | - | - |
| Total Equity | 1.32M▲ 0% | 76M▲ 5648.9% | 87.15M▲ 14.7% | 95.18M▲ 9.2% | 211.54M▲ 122.2% | 198.94M▼ 6.0% | 235.19M▲ 18.2% | 243.03M▲ 3.3% | 349M▲ 43.6% | 333.3M▲ 0% |
| Equity Growth % | - | 5648.87% | 14.67% | 9.21% | 122.25% | -5.95% | 18.22% | 3.33% | 43.6% | 44.87% |
| Book Value per Share | 0.08 | 4.49 | 3.85 | 3.75 | 5.98 | 4.42 | 3.84 | 3.92 | 5.51 | 4.37 |
| Total Shareholders' Equity | 1.32M | 76M | 87.15M | 95.18M | 211.54M | 198.94M | 235.19M | 243.03M | 349M | 333.3M |
| Common Stock | 1K | 16K | 23K | 28K | 41K | 52K | 62K | 54K | 67K | 67K |
| Retained Earnings | -35.54M | -68.12M | -150.8M | -221.62M | -302.47M | -412.34M | -509.67M | -519.4M | -594.28M | -613.17M |
| Treasury Stock | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Accumulated OCI | -893K | -1.96M | -110.44M | -2K | -397K | -797K | -136K | 130K | 0 | -513K |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fulcrum Therapeutics, Inc. (FULC) cash flow — operating, investing & free cash flow history
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 | TTM |
|---|---|---|---|---|---|---|---|---|---|---|
| Cash from Operations | -20.07M | -22.56M | -39.48M | -53.66M | -78.48M | -97.05M | -90.97M | -2.22M | -60.06M | -60.06M |
| Operating CF Margin % | - | - | - | -608.13% | -409.53% | -1530.27% | -3242.96% | -2.77% | - | - |
| Operating CF Growth % | - | -12.39% | -75% | -35.89% | -46.26% | -23.67% | 6.27% | 97.56% | -2608.07% | -120.98% |
| Net Income | -22.96M | -32.59M | -82.68M | -70.82M | -80.85M | -109.87M | -97.33M | -9.72M | -74.88M | -76.12M |
| Depreciation & Amortization | 715K | 1.34M | 2.05M | 2.38M | 2.52M | 2.41M | 2.17M | 1.59M | 1.39M | 1.33M |
| Stock-Based Compensation | 1.37M | 2.16M | 4.22M | 7.35M | 11.07M | 13.35M | 14.8M | 14.55M | 12.47M | 9.8M |
| Deferred Taxes | 0 | 0 | 0 | 1.93M | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | 2.59M | 4.87M | 25.59M | -2M | 673K | 152K | -5.99M | -4.39M | -2.95M | -2.71M |
| Working Capital Changes | 804K | 6.52M | 11.33M | 7.5M | -11.89M | -3.09M | -4.61M | -4.25M | 3.91M | 4.13M |
| Change in Receivables | 0 | 0 | 0 | -2M | -500K | 2.5M | -308K | -1.56M | 2.1M | 979K |
| Change in Inventory | 0 | 0 | 0 | 229K | 1.25M | 0 | 0 | 0 | 0 | 0 |
| Change in Payables | 208K | -20K | 803K | 1.77M | 973K | -1.18M | -853K | -1.59M | 428K | 943K |
| Cash from Investing | -1.91M | -8.98M | -944K | -57.14M | -129.67M | 12.41M | -36.69M | 32.23M | 30.72M | -96.71M |
| Capital Expenditures | -1.91M | -8.98M | -853K | -1.34M | -1.71M | -1.96M | -508K | -278K | -314K | -322K |
| CapEx % of Revenue | - | - | - | 15.21% | 8.94% | 30.95% | 18.11% | 0.35% | - | - |
| Acquisitions | 0 | 0 | 0 | 55.8M | 127.96M | -14.38M | 0 | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - | - |
| Other Investing | 0 | 0 | -91K | -55.8M | -127.96M | 14.38M | 0 | 0 | 0 | 0 |
| Cash from Financing | 17.66M | 105.03M | 64.34M | 71.13M | 186.51M | 84.32M | 118.12M | 2.75M | 168.67M | 168.35M |
| Debt Issued (Net) | 0 | -70K | -45K | -50K | -18K | 0 | 0 | 0 | 0 | 0 |
| Equity Issued (Net) | 0 | 105.08M | 64.14M | 69.95M | 182.86M | 80.8M | 117.34M | 2.75M | 168.67M | 168.67M |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing | 17.66M | 12K | 249K | 1.24M | 3.67M | 3.52M | 777K | 0 | 0 | -312K |
| Net Change in Cash | -4.32M▲ 0% | 73.48M▲ 1801.0% | 23.92M▼ 67.5% | -39.66M▼ 265.8% | -21.64M▲ 45.4% | -314K▲ 98.5% | -9.54M▼ 2936.6% | 32.76M▲ 443.6% | 139.32M▲ 325.3% | 8.09M▲ 0% |
| Free Cash Flow | -21.98M▲ 0% | -31.54M▼ 43.5% | -40.34M▼ 27.9% | -55M▼ 36.3% | -80.19M▼ 45.8% | -99.01M▼ 23.5% | -91.47M▲ 7.6% | -2.5M▲ 97.3% | -60.38M▼ 2319.0% | -63.88M▲ 0% |
| FCF Margin % | - | - | - | -623.34% | -418.47% | -1561.23% | -3261.07% | -3.12% | - | - |
| FCF Growth % | - | -43.49% | -27.88% | -36.35% | -45.81% | -23.47% | 7.62% | 97.27% | -2319.03% | -945.09% |
| FCF per Share | -1.30 | -1.86 | -1.78 | -2.17 | -2.27 | -2.20 | -1.49 | -0.04 | -0.95 | -0.95 |
| FCF Conversion (FCF/Net Income) | 0.87x | 0.69x | 0.48x | 0.76x | 0.97x | 0.88x | 0.93x | 0.23x | 0.80x | 0.84x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fulcrum Therapeutics, Inc. (FULC) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios
| Metric | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | TTM |
|---|---|---|---|---|---|---|---|---|---|
| Return on Equity (ROE) | -84.29% | -101.35% | -77.68% | -52.72% | -53.53% | -44.84% | -4.07% | -25.3% | -27.8% |
| Return on Invested Capital (ROIC) | -129.67% | - | -375.11% | -56.74% | -47.78% | -41.74% | -7.94% | -36.19% | -36.19% |
| Gross Margin | - | - | -569.18% | -263.73% | -1110.69% | 100% | 20.77% | - | - |
| Net Margin | - | - | -802.66% | -421.89% | -1732.43% | -3470.05% | -12.16% | - | - |
| Debt / Equity | 0.00x | 0.00x | 0.00x | - | 0.07x | 0.05x | 0.04x | 0.02x | 0.02x |
| FCF Conversion | 0.69x | 0.48x | 0.76x | 0.97x | 0.88x | 0.93x | 0.23x | 0.80x | 0.84x |
| Revenue Growth | - | - | - | 117.19% | -66.91% | -55.77% | 2752.05% | -100% | -100% |
Fulcrum Therapeutics, Inc. (FULC) SEC filings — annual & quarterly reports (10-K, 10-Q)
Apr 27, 2026·SEC
Feb 24, 2026·SEC
Jan 12, 2026·SEC
Fulcrum Therapeutics, Inc. (FULC) stock FAQ — growth, dividends, profitability & financials explained
Fulcrum Therapeutics, Inc. (FULC) saw revenue decline by 100.0% over the past year.
Fulcrum Therapeutics, Inc. (FULC) reported a net loss of $76.1M for fiscal year 2025.
Fulcrum Therapeutics, Inc. (FULC) has a return on equity (ROE) of -25.3%. Negative ROE indicates the company is unprofitable.
Fulcrum Therapeutics, Inc. (FULC) had negative free cash flow of $63.9M in fiscal year 2025, likely due to heavy capital investments.
Fulcrum Therapeutics, Inc. (FULC) financial analysis — history, returns, DCA and operating performance tools
Historical returns with dividends reinvested
Dollar cost averaging vs lump sum
Yield, growth, payout safety & DRIP
EPS trends, net income & profitability
Long-term charts & historical price data
Sales growth patterns & revenue breakdown
30 years of market, efficiency and balance-sheet ratios
DCF intrinsic value, peer multiples & estimates