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FULCFulcrum Therapeutics, Inc.
$3.69$200M
Overview & Tools
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FULC logo

Fulcrum Therapeutics, Inc.

FULC
NASDAQ · Biotechnology
$3.69
At close - Oct 2, 4:00 PM EDT - USD
Market Cap$200M
P/E-3.1x
52W High$15.74
Volume1.54M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q1

Clinical Development Costs Outpace Recurring Revenue Streams

Fulcrum Therapeutics remains a high-risk, pre-revenue biotechnology entity heavily reliant on the success of its FulcrumSeek platform and the Phase 3 REACH trial. While the firm maintains a temporary liquidity buffer, the persistent quarterly R&D burn rate of ...

GrowthContracting
ProfitabilityNegative
ValuationReview
TechnicalsWeak
Explore valuation models
MARKET ACTION

FULC price & volume

Price trend, volume and key moving averages

Launch Terminal
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Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

7/12 Beats

EPS beat 7 of last 12 quarters

02

Valuation risk

-109% Peers

P/E is 109% below peer median

03

Market leadership

RS 13 · Lag

Laggard (Underperforming 87% of market)

04

Weak Trend

Below 200DMA

Price < 200DMA

Next CatalystEstimated earnings · Oct 31

Market performance

Price History →

Trailing total returns as of 10/3/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
FULC-66.21%
S&P 500 (^GSPC)+12.66%
1-Year Return
FULC-61.20%
S&P 500 (^GSPC)+15.01%
3-Year Return
FULC-9.78%
S&P 500 (^GSPC)+80.50%
5-Year Return
FULC-86.07%
S&P 500 (^GSPC)+87.46%

Growth & profitability

Annual revenue & EPS trend
Revenue
-
Net income
-$75M-670.0% YoY
Free cash flow
-$60M-2319.0% YoY
Operating margin
-
ROIC (TTM)-36.2%
Avg ROIC 5Y-
ROE (TTM)-25.3%
Piotroski Score3 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate7/12 (58%)
Revenue Beat Rate2/12 (100%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Jul 31, 2026
-$0.34-39.7%
vs -$0.24
—
vs —
Q3 2026
Jul 30, 2026
-$0.34-39.7%
vs -$0.24
—
vs —
Q2 2026
Apr 27, 2026
-$0.25+19.4%
vs -$0.31
—
vs —
Q1 2026
Feb 24, 2026
-$0.31+0.0%
vs -$0.31
—
vs —
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

5 Stories
Newsfile Corp·2d ago
Kaplan Fox is Investigating Fulcrum Therapeutics, Inc. (FULC) and its Board for Possible Securities Law Violations

New York, New York--(Newsfile Corp. - September 30, 2026) - Kaplan Fox & Kilsheimer LLP is investigating potential securities violations against Fulcrum Therapeutics, Inc. ("Fulcrum Therapeutics" or the "Company") (NASDAQ: FULC). CLICK HERE TO RECEIVE MORE INFORMATION ABOUT THIS INVESTIGATION If you are a Fulcrum Therapeutics investor and have suffered losses, or if you have information that could assist in the Fulcrum Therapeutics investigation, you may CLICK HERE to contact us.

Defense World·6d ago
Fulcrum Therapeutics, Inc. (NASDAQ:FULC) Receives Consensus Rating of “Reduce” from Brokerages

Shares of Fulcrum Therapeutics, Inc. (NASDAQ: FULC - Get Free Report) have been assigned a consensus recommendation of "Reduce" from the twelve research firms that are presently covering the company, MarketBeat reports. Four investment analysts have rated the stock with a sell recommendation, seven have assigned a hold recommendation and one has assigned a buy recommendation

Newsfile Corp·Sep 24, 2026
Kaplan Fox Alerts Fulcrum Therapeutics, Inc. (FULC) Investors: The Firm is Investigating Possible Securities Law Violations

New York, New York--(Newsfile Corp. - September 24, 2026) - Kaplan Fox & Kilsheimer LLP is investigating potential securities violations against Fulcrum Therapeutics, Inc. ("Fulcrum Therapeutics" or the "Company") (NASDAQ: FULC). CLICK HERE TO RECEIVE MORE INFORMATION ABOUT THIS INVESTIGATION If you are a Fulcrum Therapeutics investor and have suffered losses, or if you have information that could assist in the Fulcrum Therapeutics investigation, you may CLICK HERE to contact us.

Defense World·Sep 17, 2026
Reviewing Fulcrum Therapeutics (NASDAQ:FULC) & Biogen (NASDAQ:BIIB)

Biogen (NASDAQ: BIIB - Get Free Report) and Fulcrum Therapeutics (NASDAQ: FULC - Get Free Report) are both healthcare companies, but which is the better investment? We will compare the two companies based on the strength of their institutional ownership, valuation, risk, analyst recommendations, earnings, dividends and profitability. Earnings and Valuation This table compares Biogen and Fulcrum

Filtered for Fulcrum Therapeutics, Inc.More Headlines
04

Compare before deciding

Benchmark FULC against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Fulcrum Therapeutics, Inc. (FULC)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
FULC logoFULCFulcrum Therapeutics, Inc.Current
$3.69$199.67M-3.13-100%—-25.3%—
ARWR logoARWRArrowhead Pharmaceuticals, Inc.
$64.19$9.04B-5261.4823258.15%-47.79%-60.05%—
SRPT logoSRPTSarepta Therapeutics, Inc.
$17.50$1.85B-2.4515.58%-6.93%-9.96%—
FOLD logoFOLDAmicus Therapeutics, Inc.
$14.49$4.55B-164.8520.05%-4.27%-12.02%—
RARE logoRAREUltragenyx Pharmaceutical Inc.
$15.22$1.5B-2.6120.13%-81.79%——
CRSP logoCRSPCRISPR Therapeutics AG
$55.43$5.35B-8.57-89.97%-3368.72%-24.39%—

Compare FULC vs Peers

Fulcrum Therapeutics, Inc. (FULC) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ARWR

Most directly comparable listed peer for FULC.

Scale Benchmark

vs IQV

Larger-name benchmark to compare FULC against a more recognizable public peer.

Peer Set

Compare Top 5

vs ARWR, SRPT, FOLD, RARE

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

FULC SEC Filings & Documents

Fulcrum Therapeutics, Inc. (FULC) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Jun 25, 2026·SEC

Material company update

Jun 11, 2026·SEC

Material company update

Jun 4, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 24, 2026·SEC

FY 2025

Feb 25, 2025·SEC

FY 2024

Feb 27, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Jul 30, 2026·SEC

FY 2026

Apr 27, 2026·SEC

FY 2025

Oct 29, 2025·SEC

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FULC Frequently Asked Questions

Fulcrum Therapeutics, Inc. (FULC) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
How fast is Fulcrum Therapeutics, Inc. growing?

Fulcrum Therapeutics, Inc. (FULC) saw revenue decline by 100.0% over the past year.

Is FULC profitable?

Fulcrum Therapeutics, Inc. (FULC) reported a net loss of $85.0M for fiscal year 2025.

Dividend & Returns
What is FULC's return on equity?

Fulcrum Therapeutics, Inc. (FULC) has a return on equity (ROE) of -25.3%. Negative ROE indicates the company is unprofitable.

What is Fulcrum Therapeutics, Inc.'s free cash flow?

Fulcrum Therapeutics, Inc. (FULC) had negative free cash flow of $66.1M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in FULC back in 2017?

Total return calculator · dividends reinvested · 9+ years of data

See returns →