Bull case
GILD would need investors to value it at roughly 16x earnings — about 0x more generous than today's 16x forward P/E. That requires meaningful multiple expansion on top of continued earnings growth.
Wall Street verdict, consensus price target, and analyst rating breakdown — everything needed to frame the risk/reward at today's price.
Three scenarios for where GILD stock could go
GILD would need investors to value it at roughly 16x earnings — about 0x more generous than today's 16x forward P/E. That requires meaningful multiple expansion on top of continued earnings growth.
This is close to how the market is already pricing GILD — at roughly 16x forward earnings. No dramatic re-rating needed, just steady execution on the core business.
If investor confidence fades or macro conditions deteriorate, a 14x multiple contraction could push GILD down roughly 90% from where it trades now.
Not financial advice. Model confidence reflects internal scenario assumptions, not a guarantee of returns. Past performance does not predict future results.

Gilead Sciences is a biopharmaceutical company focused on developing and commercializing medicines for serious diseases like HIV, viral hepatitis, and cancer. It generates revenue primarily from antiviral drugs — especially HIV treatments like Biktarvy which drive the majority of sales — along with oncology therapies and COVID-19 treatment Veklury. The company's moat lies in its deep expertise in antiviral drug development, a robust HIV franchise with high patient retention, and a pipeline of cell therapy and oncology assets.
Quarterly beat-or-miss track record against analyst estimates, plus forward revenue and EPS outlook for the next two fiscal years.
| Quarter | EPS (Actual / Est) | EPS Surprise | Revenue (Actual / Est) | Rev Surprise |
|---|---|---|---|---|
| Q2 2025 | $1.81/$1.78 | +1.7% | $6.7B/$6.8B | -2.1% |
| Q3 2025 | $2.01/$1.96 | +2.6% | $7.1B/$7.0B | +1.4% |
| Q4 2025 | $2.47/$2.13 | +16.0% | $7.8B/$7.4B | +4.3% |
| Q1 2026 | $1.86/$1.81 | +2.8% | $7.9B/$7.7B | +3.1% |
GILD beat EPS estimates in 4 of 4 tracked quarters. A perfect track record raises the bar for the upcoming report.
Product and geographic revenue mix from the latest annual disclosure, with year-over-year growth by segment.
Latest annual revenue by segment or product family
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Latest annual revenue by reported region
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Current multiples compared to the S&P 500, the company's sector, and its own five-year average.
Fair value est. $94 — implies -28.9% from today's price.
| Metric | GILD | S&P 500 | Healthcare | 5Y Avg GILD |
|---|---|---|---|---|
| Forward PE | 15.6x | 19.1x-18% | 18.8x-17% | — |
| Trailing PE | 351.3x | 25.1x+1299% | 22.2x+1483% | 18.8x+1771% |
| PEG Ratio | — | 1.72x | 1.53x | — |
| EV/EBITDA | 41.3x | 15.2x+172% | 14.0x+195% | 16.5x+150% |
| Price/FCF | 16.1x | 21.1x-23% | 18.6x-13% | 11.2x+44% |
| Price/Sales | 5.8x | 3.1x+85% | 2.8x+106% | 3.6x+60% |
| Dividend Yield | 2.34% | 1.87% | 1.42% | 3.83% |
Forward P/E and PEG reflect analyst consensus estimates. Historical averages use trailing ratios where forward data is unavailable.S&P 500 and sector benchmarks both use trailing median P/E — similar readings indicate the broader index and sector are priced alike.
Open valuation toolGILD generates $9.7B in free cash flow at a 32.8% margin — returns 3.0% of market cap to shareholders annually.
Revenue, margins, and cash generation
ROIC, leverage, and debt serviceability
~1.7 years to full repayment at current FCF run-rate
* Elevated by buyback-compressed equity — compare ROIC (3.2%) for an undistorted picture of capital efficiency.
How capital is returned to owners
All figures from the trailing twelve months. ROIC uses invested capital (equity + net debt). ROE marked * where buyback-compressed equity base may inflate the figure.
Open full ratios pageKey factors that could pressure the stock price, compress the multiple, or weigh on future results.
AI analysis · updated April 11, 2026
FDA has placed clinical holds on investigational HIV drugs GS‑1720 and GS‑4182 due to safety signals such as decreased CD4+ T‑cell counts. These holds can delay market entry, increase development costs, and postpone expected revenue streams.
Nearly 75% of Gilead’s product revenue comes from its HIV portfolio. A patent expiration for a top‑selling HIV drug is slated for 2033, exposing the company to significant revenue erosion if no new HIV products are launched.
Gilead’s growth depends on successful development and commercialization of new products. A Phase 3 trial of Trodelvy in breast cancer failed to meet its primary endpoint, illustrating the high risk of costly R&D failures.
The biopharma sector is highly competitive, with rivals advancing oncology and cell‑therapy products that could erode Gilead’s market share and pressure pricing.
Ongoing SEC investigations into oncology revenue reporting and class‑action lawsuits introduce potential fines, financial penalties, and reputational harm that could affect investor confidence.
A sizable portion of sales originates outside the U.S., making Gilead vulnerable to Euro and other currency swings that can compress earnings and cash flow.
These are risk mechanisms, not predictions. The key question is which would force a cut to earnings estimates or a lower multiple than the market currently prices in.
Structural drivers behind the upside case and why the stock could outperform over the next 12 months.
AI analysis · updated April 11, 2026
Gilead’s HIV business remains a consistent profit driver, with sales growing year‑over‑year and new products such as Yeztugo and Biktarvy expanding its market share. The company’s next‑generation therapies are positioned to capture additional revenue from patients seeking improved efficacy and tolerability.
Recent acquisitions—Arcellx’s CAR‑T therapy anito‑cel and Tubulis’s antibody‑drug conjugate technology—are bolstering Gilead’s oncology presence. Revenue estimates for Trodelvy have been raised, reflecting growing confidence in the company’s cancer drug portfolio.
Gilead is pursuing collaborations such as with Galapagos NV for autoimmune disease treatments and has acquired Ouro Medicines to advance its pipeline. These moves diversify revenue streams and reduce reliance on legacy products.
The company is entering its most active pipeline year in over a decade, with several near‑term launches planned and a strong focus on high‑value therapeutic areas. This heightened innovation activity is expected to drive future growth.
Gilead has shown steady revenue growth and a solid return on equity, while offering an attractive dividend yield. These financial fundamentals support a positive outlook for the stock.
A real bull case compounds — each driver matters most when it strengthens margins, supports capital returns, and keeps the company above the market's minimum growth bar simultaneously.
52-week range context and price returns across multiple time horizons. Dividend contribution is shown separately in the Capital Return section.
Range context matters because valuation compression and earnings misses rarely hit from the same starting point. A stock already far below its high can still fall, but it is no longer carrying the same embedded optimism as one pressing a fresh peak.
Valuation, growth, and margin comparison against the closest publicly traded peers for this company.
| Company | Mkt Cap | Fwd PE | Rev Grw | Margin | Rating | Upside |
|---|---|---|---|---|---|---|
GIL GILD Gilead Sciences, Inc. | $166.3B | 15.6x | +3.5% | 28.9% | Buy | +21.3% |
ABB ABBV AbbVie Inc. | $364.6B | 14.5x | +7.7% | 6.9% | Buy | +24.5% |
BMY BMY Bristol-Myers Squibb Company | $116.2B | 9.0x | -0.6% | 15.0% | Hold | +8.9% |
AMG AMGN Amgen Inc. | $177.9B | 14.8x | +4.5% | 20.9% | Buy | +6.4% |
BII BIIB Biogen Inc. | $27.9B | 12.9x | -0.5% | 13.9% | Buy | +11.8% |
REG REGN Regeneron Pharmaceuticals, Inc. | $73.0B | 15.2x | +5.5% | 29.6% | Buy | +23.3% |
This peer comparison reflects companies with similar business models, product lines, or market positioning, supplemented by industry grouping when direct matches are limited.
GILD returns 3.0% total yield, led by a 2.34% dividend, raised 10 consecutive years. Buybacks add another 0.7%.
Yield, cadence, and growth quality
How much per-share support comes from repurchases
| Year | Div / Share | YoY Grw | BB Yield | Total Yield |
|---|---|---|---|---|
| 2026 | $0.82 | — | — | — |
| 2025 | $3.16 | +2.6% | — | — |
| 2024 | $3.08 | +2.7% | 1.0% | 4.4% |
| 2023 | $3.00 | +2.7% | 1.0% | 4.7% |
| 2022 | $2.92 | +2.8% | 1.3% | 4.7% |
Common questions answered from live analyst data and company financials.
Gilead Sciences, Inc. (GILD) is rated Buy by Wall Street analysts as of 2026. Of 58 analysts covering the stock, 37 rate it Buy or Strong Buy, 20 rate it Hold, and 1 rate it Sell or Strong Sell. The consensus 12-month price target is $162, implying +21.3% from the current price of $133. The bear case scenario is $14 and the bull case is $136.
The Wall Street consensus price target for GILD is $162 based on 58 analyst estimates. The high-end target is $180 (+34.9% from today), and the low-end target is $133 (-0.4%). The base case model target is $133.
GILD trades at 15.6x times forward earnings. The stock trades at a notable premium to the broad market, which is typical for businesses with strong free cash flow and above-average growth expectations. Based on current multiples versus the peer group, the relative model signals overvalued. Whether the stock is over or undervalued ultimately depends on whether consensus earnings estimates are achievable.
The primary risks for GILD in 2026 are: (1) Regulatory Holds & Safety Signals — FDA has placed clinical holds on investigational HIV drugs GS‑1720 and GS‑4182 due to safety signals such as decreased CD4+ T‑cell counts. (2) HIV Revenue Concentration — Nearly 75% of Gilead’s product revenue comes from its HIV portfolio. (3) Drug Development Failure Risk — Gilead’s growth depends on successful development and commercialization of new products. Each factor has the potential to pressure earnings or compress the stock's valuation multiple.
Analyst consensus estimates GILD will report consensus revenue of $30.5B (+3.5% year-over-year) and EPS of $7.73 (+13.8% year-over-year) for the upcoming fiscal year. The following year, analysts project $32.2B in revenue.
Gilead Sciences, Inc. is expected to report its next earnings on approximately 2026-05-07. Consensus expects EPS of $1.89 and revenue of $6.9B. Over recent quarters, GILD has beaten EPS estimates 75% of the time.
Gilead Sciences, Inc. (GILD) generated $9.7B in free cash flow over the trailing twelve months — a free cash flow margin of 32.8%. GILD returns capital to shareholders through dividends (2.3% yield) and share repurchases ($1.1B TTM).