Bull case
AMGN would need investors to value it at roughly 28x earnings — about 14x more generous than today's 15x forward P/E. That requires meaningful multiple expansion on top of continued earnings growth.
Wall Street verdict, consensus price target, and analyst rating breakdown — everything needed to frame the risk/reward at today's price.
Three scenarios for where AMGN stock could go
AMGN would need investors to value it at roughly 28x earnings — about 14x more generous than today's 15x forward P/E. That requires meaningful multiple expansion on top of continued earnings growth.
At 21x on FY1 earnings, the base case reflects a reasonable but not stretched valuation. It prices in continued growth without assuming an exceptional setup.
If investor confidence fades or macro conditions deteriorate, a 5x multiple contraction could push AMGN down roughly 31% from where it trades now.
Not financial advice. Model confidence reflects internal scenario assumptions, not a guarantee of returns. Past performance does not predict future results.

Amgen is a global biotechnology company that discovers, develops, manufactures, and markets innovative human therapeutics for serious illnesses. It generates revenue primarily from sales of its branded biologic medicines — with key products including Enbrel, Prolia, Otezla, and Repatha — across therapeutic areas like oncology, inflammation, bone health, and cardiovascular disease. The company's moat lies in its deep expertise in complex biologics manufacturing, extensive patent protection for its innovative therapies, and a robust pipeline of novel drug candidates.
Quarterly beat-or-miss track record against analyst estimates, plus forward revenue and EPS outlook for the next two fiscal years.
| Quarter | EPS (Actual / Est) | EPS Surprise | Revenue (Actual / Est) | Rev Surprise |
|---|---|---|---|---|
| Q3 2025 | $6.02/$5.28 | +14.0% | $9.2B/$8.9B | +2.6% |
| Q4 2025 | $5.64/$5.02 | +12.4% | $9.6B/$9.0B | +6.6% |
| Q1 2026 | $5.29/$4.73 | +11.8% | $9.9B/$9.5B | +4.1% |
| Q2 2026 | $5.15/$4.77 | +8.0% | $8.6B/$8.6B | +0.5% |
AMGN beat EPS estimates in 4 of 4 tracked quarters. A perfect track record raises the bar for the upcoming report.
Product and geographic revenue mix from the latest annual disclosure, with year-over-year growth by segment.
Latest annual revenue by segment or product family
Tap, hover, or focus a slice to inspect segment detail.
Latest annual revenue by reported region
Tap, hover, or focus a slice to inspect segment detail.
Current multiples compared to the S&P 500, the company's sector, and its own five-year average.
Fair value est. $354 — implies +7.3% from today's price.
| Metric | AMGN | S&P 500 | Healthcare | 5Y Avg AMGN |
|---|---|---|---|---|
| Forward PE | 14.8x | 19.1x-23% | 18.8x-22% | — |
| Trailing PE | 23.2x | 25.1x | 22.2x | 24.8x |
| PEG Ratio | 7.87x | 1.72x+359% | 1.53x+415% | — |
| EV/EBITDA | 14.1x | 15.2x | 14.0x | 14.7x |
| Price/FCF | 22.0x | 21.1x | 18.6x+18% | 17.6x+25% |
| Price/Sales | 4.8x | 3.1x+55% | 2.8x+73% | 5.0x |
| Dividend Yield | 2.87% | 1.87% | 1.42% | 3.06% |
Forward P/E and PEG reflect analyst consensus estimates. Historical averages use trailing ratios where forward data is unavailable.S&P 500 and sector benchmarks both use trailing median P/E — similar readings indicate the broader index and sector are priced alike.
Open valuation toolAMGN generates $8.6B in free cash flow at a 23.1% margin — 14.8% ROIC signals a durable competitive advantage · returns 2.9% of market cap to shareholders annually.
Revenue, margins, and cash generation
ROIC, leverage, and debt serviceability
~5.3 years to full repayment at current FCF run-rate
* Elevated by buyback-compressed equity — compare ROIC (14.8%) for an undistorted picture of capital efficiency.
How capital is returned to owners
All figures from the trailing twelve months. ROIC uses invested capital (equity + net debt). ROE marked * where buyback-compressed equity base may inflate the figure.
Open full ratios pageKey factors that could pressure the stock price, compress the multiple, or weigh on future results.
AI analysis · updated April 11, 2026
Amgen faces material adverse effects from the Inflation Reduction Act (IRA) and Medicare redesign, which impose drug pricing controls that could reduce sales and operations through the end of the decade. Medicare Part D has already set a price for Enbrel, expected to cut its profitability starting in 2026.
The entry of additional biosimilar and generic competitors threatens Amgen’s market share and pricing power. While Amgen holds early advantage with Pavblu and Wezlana, established products such as Prolia and Xgeva face biosimilar competition, and the success of its diabetes/obesity drug MariTide hinges on differentiation.
Amgen’s heavy R&D spend carries the risk of clinical trial failures or regulatory rejections, which could delay product launches and hurt financial performance. The commercial success of new drugs like MariTide is critical to offset erosion from older products.
Amgen relies on third‑party manufacturers for certain devices and processes; failures or delays in development, modification, or regulatory approval could increase costs and postpone market entry. Expansion of manufacturing capacity in a complex environment also exposes the company to supply‑chain and tariff risks.
Amgen’s net debt was $48.6 billion as of March 2025, and while interest coverage ratios suggest manageable debt, investors should monitor debt levels and potential impacts on capital raising and financial flexibility.
These are risk mechanisms, not predictions. The key question is which would force a cut to earnings estimates or a lower multiple than the market currently prices in.
Structural drivers behind the upside case and why the stock could outperform over the next 12 months.
AI analysis · updated April 11, 2026
Amgen’s diverse portfolio includes numerous drugs with double‑digit sales growth. High‑value assets span oncology, cardiovascular, inflammation, and rare diseases. Upcoming catalysts include new therapies for atopic dermatitis, a cholesterol‑lowering drug, gastric cancer trial readouts, and positive Phase 3 results for subcutaneous Tepezza.
The company posted a 12% year‑over‑year revenue increase, surpassing market expectations. 2025 forecasts show double‑digit growth in both revenue and EPS, with 14 products exceeding $1 billion in sales. EPS reached $5.29, beating analyst estimates.
Amgen’s obesity and cardiovascular drugs, along with a broad late‑stage pipeline, are expected to lift revenue and cash generation.
AI‑supported research and development, a global footprint, and potential M&A activities enable continuous product launches while managing pricing pressures. Operational execution and a diversified revenue base support sustained earnings momentum.
Amgen reports a return on equity of 148.37%, underscoring strong profitability and efficient capital use.
A real bull case compounds — each driver matters most when it strengthens margins, supports capital returns, and keeps the company above the market's minimum growth bar simultaneously.
52-week range context and price returns across multiple time horizons. Dividend contribution is shown separately in the Capital Return section.
Range context matters because valuation compression and earnings misses rarely hit from the same starting point. A stock already far below its high can still fall, but it is no longer carrying the same embedded optimism as one pressing a fresh peak.
Valuation, growth, and margin comparison against the closest publicly traded peers for this company.
| Company | Mkt Cap | Fwd PE | Rev Grw | Margin | Rating | Upside |
|---|---|---|---|---|---|---|
AMG AMGN Amgen Inc. | $177.9B | 14.8x | +4.5% | 20.9% | Buy | +6.4% |
GIL GILD Gilead Sciences, Inc. | $166.3B | 15.6x | +3.5% | 28.9% | Buy | +21.3% |
BII BIIB Biogen Inc. | $27.9B | 12.9x | -0.5% | 13.9% | Buy | +11.8% |
REG REGN Regeneron Pharmaceuticals, Inc. | $73.0B | 15.2x | +5.5% | 29.6% | Buy | +23.3% |
VRT VRTX Vertex Pharmaceuticals Incorporated | $107.9B | 22.1x | +9.3% | 35.4% | Buy | +30.1% |
BMY BMY Bristol-Myers Squibb Company | $116.2B | 9.0x | -0.6% | 15.0% | Hold | +8.9% |
This peer comparison reflects companies with similar business models, product lines, or market positioning, supplemented by industry grouping when direct matches are limited.
AMGN returns 2.9% total yield, led by a 2.87% dividend, raised 15 consecutive years.
Yield, cadence, and growth quality
How much per-share support comes from repurchases
| Year | Div / Share | YoY Grw | BB Yield | Total Yield |
|---|---|---|---|---|
| 2026 | $5.04 | — | — | — |
| 2025 | $9.52 | +5.8% | 0.0% | 2.9% |
| 2024 | $9.00 | +5.6% | 0.1% | 3.6% |
| 2023 | $8.52 | +9.8% | 0.0% | 2.9% |
| 2022 | $7.76 | +10.2% | 4.5% | 7.4% |
Common questions answered from live analyst data and company financials.
Amgen Inc. (AMGN) is rated Buy by Wall Street analysts as of 2026. Of 38 analysts covering the stock, 22 rate it Buy or Strong Buy, 13 rate it Hold, and 3 rate it Sell or Strong Sell. The consensus 12-month price target is $351, implying +6.4% from the current price of $330. The bear case scenario is $227 and the bull case is $633.
The Wall Street consensus price target for AMGN is $351 based on 38 analyst estimates. The high-end target is $432 (+31.1% from today), and the low-end target is $185 (-43.9%). The base case model target is $464.
AMGN trades at 14.8x times forward earnings. The stock's valuation is broadly in line with the broader market. Based on current multiples versus the peer group, the relative model signals slightly undervalued. Whether the stock is over or undervalued ultimately depends on whether consensus earnings estimates are achievable.
The primary risks for AMGN in 2026 are: (1) Legal & Regulatory — Amgen faces material adverse effects from the Inflation Reduction Act (IRA) and Medicare redesign, which impose drug pricing controls that could reduce sales and operations through the end of the decade. (2) Competition & Biosimilars — The entry of additional biosimilar and generic competitors threatens Amgen’s market share and pricing power. (3) Technology & Innovation — Amgen’s heavy R&D spend carries the risk of clinical trial failures or regulatory rejections, which could delay product launches and hurt financial performance. Each factor has the potential to pressure earnings or compress the stock's valuation multiple.
Analyst consensus estimates AMGN will report consensus revenue of $38.9B (+4.5% year-over-year) and EPS of $19.93 (+39.0% year-over-year) for the upcoming fiscal year. The following year, analysts project $41.9B in revenue.
A confirmed upcoming earnings date for AMGN is not yet available. Check the Earnings section above for the most recent quarterly report dates and forward estimates.
Amgen Inc. (AMGN) generated $8.6B in free cash flow over the trailing twelve months — a free cash flow margin of 23.1%. AMGN returns capital to shareholders through dividends (2.9% yield) and share repurchases ($0 TTM).