Bull case
AMGN would need investors to value it at roughly 29x earnings — about 13x more generous than today's 15x forward P/E. That requires meaningful multiple expansion on top of continued earnings growth.
Wall Street verdict, consensus price target, and analyst rating breakdown — everything needed to frame the risk/reward at today's price.
Three scenarios for where AMGN stock could go
AMGN would need investors to value it at roughly 29x earnings — about 13x more generous than today's 15x forward P/E. That requires meaningful multiple expansion on top of continued earnings growth.
At 22x on FY1 earnings, the base case reflects a reasonable but not stretched valuation. It prices in continued growth without assuming an exceptional setup.
If investor confidence fades or macro conditions deteriorate, a 1x multiple contraction could push AMGN down roughly 10% from where it trades now.
Not financial advice. Model confidence reflects internal scenario assumptions, not a guarantee of returns. Past performance does not predict future results.

Amgen is a global biotechnology company that discovers, develops, manufactures, and markets innovative human therapeutics for serious illnesses. It generates revenue primarily from sales of its branded biologic medicines — with key products including Enbrel, Prolia, Otezla, and Repatha — across therapeutic areas like oncology, inflammation, bone health, and cardiovascular disease. The company's moat lies in its deep expertise in complex biologics manufacturing, extensive patent protection for its innovative therapies, and a robust pipeline of novel drug candidates.
Quarterly beat-or-miss track record against analyst estimates, plus forward revenue and EPS outlook for the next two fiscal years.
| Quarter | EPS (Actual / Est) | EPS Surprise | Revenue (Actual / Est) | Rev Surprise |
|---|---|---|---|---|
| Q3 2025 | $6.02/$5.28 | +14.0% | $9.2B/$8.9B | +2.6% |
| Q4 2025 | $5.64/$5.02 | +12.4% | $9.6B/$9.0B | +6.6% |
| Q1 2026 | $5.29/$4.73 | +11.8% | $9.9B/$9.5B | +4.1% |
| Q2 2026 | $5.15/$4.77 | +8.0% | $8.6B/$8.6B | +0.5% |
AMGN beat EPS estimates in 4 of 4 tracked quarters. A perfect track record raises the bar for the upcoming report.
Product and geographic revenue mix from the latest annual disclosure, with year-over-year growth by segment.
Latest annual revenue by segment or product family
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Latest annual revenue by reported region
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Current multiples compared to the S&P 500, the company's sector, and its own five-year average.
Fair value est. $274 — implies -18.8% from today's price.
| Metric | AMGN | S&P 500 | Healthcare | 5Y Avg AMGN |
|---|---|---|---|---|
| Forward PE | 15.1x | 18.8x-20% | 18.3x-18% | — |
| Trailing PE | 23.7x | 24.4x | 22.1x | 24.8x |
| PEG Ratio | 8.07x | 1.66x+386% | 1.59x+407% | — |
| EV/EBITDA | 14.4x | 15.2x | 14.2x | 14.7x |
| Price/FCF | 22.5x | 20.7x | 18.5x+21% | 17.6x+28% |
| Price/Sales | 5.0x | 3.1x+60% | 2.6x+88% | 5.0x |
| Dividend Yield | 2.80% | 1.91% | 1.50% | 3.06% |
Forward P/E and PEG reflect analyst consensus estimates. Historical averages use trailing ratios where forward data is unavailable.S&P 500 and sector benchmarks both use trailing median P/E — similar readings indicate the broader index and sector are priced alike.
Open valuation toolAMGN generates $8.6B in free cash flow at a 23.1% margin — 14.8% ROIC signals a durable competitive advantage · returns 2.8% of market cap to shareholders annually.
Revenue, margins, and cash generation
ROIC, leverage, and debt serviceability
~5.3 years to full repayment at current FCF run-rate
* Elevated by buyback-compressed equity — compare ROIC (14.8%) for an undistorted picture of capital efficiency.
How capital is returned to owners
All figures from the trailing twelve months. ROIC uses invested capital (equity + net debt). ROE marked * where buyback-compressed equity base may inflate the figure.
Open full ratios pageKey factors that could pressure the stock price, compress the multiple, or weigh on future results.
AI analysis · updated June 17, 2026
Amgen faces significant risks from patent expirations, which could lead to revenue loss as exclusivity ends for key products.
Increased competition from biosimilars threatens Amgen's market share and pricing power for its biologic drugs.
Amgen's revenue is heavily concentrated in a few key products, making it vulnerable to declines in any one of them.
Ongoing regulatory and market pressures on drug pricing could negatively impact Amgen's profitability and growth.
Amgen's ability to sustain growth depends on successfully developing and commercializing new drugs in its pipeline.
Any disruptions or failures in manufacturing could lead to supply shortages and harm Amgen's reputation and financial performance.
Stringent regulatory requirements and potential legal challenges could delay approvals or increase compliance costs.
Amgen faces legal risks, such as the recent $20 million patent liability case, which could impact financials and reputation.
Analyst forecasts suggest limited upside potential for AMGN stock, with minimal growth expected by 2026.
These are risk mechanisms, not predictions. The key question is which would force a cut to earnings estimates or a lower multiple than the market currently prices in.
Structural drivers behind the upside case and why the stock could outperform over the next 12 months.
AI analysis · updated June 17, 2026
Amgen focuses on discovering and developing innovative medicines for serious illnesses with limited treatment options, leveraging biology and technology.
Amgen has demonstrated robust earnings growth, contributing to a significant stock price appreciation.
The MariTide pipeline represents a key growth driver with substantial upside potential for Amgen.
Amgen's trailing and forward P/E ratios suggest attractive valuation metrics, indicating potential for further upside.
With operations in approximately 100 countries, Amgen has a broad and diversified global reach.
Amgen's inclusion in the Dow Jones Industrial Average and Nasdaq-100 Index underscores its market prominence and stability.
As one of the largest biomedical companies by revenue, Amgen holds a strong position in the biopharmaceutical industry.
A real bull case compounds — each driver matters most when it strengthens margins, supports capital returns, and keeps the company above the market's minimum growth bar simultaneously.
52-week range context and price returns across multiple time horizons. Dividend contribution is shown separately in the Capital Return section.
Range context matters because valuation compression and earnings misses rarely hit from the same starting point. A stock already far below its high can still fall, but it is no longer carrying the same embedded optimism as one pressing a fresh peak.
Valuation, growth, and margin comparison against the closest publicly traded peers for this company.
| Company | Mkt Cap | Fwd PE | Rev Grw | Margin | Rating | Upside |
|---|---|---|---|---|---|---|
AMG AMGN Amgen Inc. | $182.2B | 15.1x | +6.2% | 20.9% | Buy | +3.5% |
GIL GILD Gilead Sciences, Inc. | $153.7B | — | +7.1% | 31.0% | Buy | +30.7% |
BII BIIB Biogen Inc. | $29.0B | 13.5x | +2.8% | 13.9% | Buy | +11.1% |
REG REGN Regeneron Pharmaceuticals, Inc. | $63.4B | 13.1x | +9.0% | 29.6% | Buy | +37.1% |
VRT VRTX Vertex Pharmaceuticals Incorporated | $114.9B | 23.4x | +11.0% | 35.4% | Buy | +22.7% |
BMY BMY Bristol-Myers Squibb Company | $110.3B | 8.5x | +1.0% | 15.0% | Hold | +15.9% |
This peer comparison reflects companies with similar business models, product lines, or market positioning, supplemented by industry grouping when direct matches are limited.
AMGN returns 2.8% total yield, led by a 2.80% dividend, raised 15 consecutive years.
Yield, cadence, and growth quality
How much per-share support comes from repurchases
| Year | Div / Share | YoY Grw | BB Yield | Total Yield |
|---|---|---|---|---|
| 2026 | $5.04 | — | — | — |
| 2025 | $9.52 | +5.8% | 0.0% | 2.9% |
| 2024 | $9.00 | +5.6% | 0.1% | 3.6% |
| 2023 | $8.52 | +9.8% | 0.0% | 2.9% |
| 2022 | $7.76 | +10.2% | 4.5% | 7.4% |
Common questions answered from live analyst data and company financials.
Amgen Inc. (AMGN) is rated Buy by Wall Street analysts as of 2026. Of 38 analysts covering the stock, 22 rate it Buy or Strong Buy, 13 rate it Hold, and 3 rate it Sell or Strong Sell. The consensus 12-month price target is $349, implying +3.5% from the current price of $338. The bear case scenario is $305 and the bull case is $638.
The Wall Street consensus price target for AMGN is $349 based on 38 analyst estimates. The high-end target is $427 (+26.5% from today), and the low-end target is $185 (-45.2%). The base case model target is $485.
AMGN trades at 15.1x times forward earnings. The stock's valuation is broadly in line with the broader market. Based on current multiples versus the peer group, the relative model signals slightly expensive versus peers. Whether the stock is over or undervalued ultimately depends on whether consensus earnings estimates are achievable.
The primary risks for AMGN in 2026 are: (1) Patent expirations — Amgen faces significant risks from patent expirations, which could lead to revenue loss as exclusivity ends for key products. (2) Biosimilar competition — Increased competition from biosimilars threatens Amgen's market share and pricing power for its biologic drugs. (3) Revenue concentration — Amgen's revenue is heavily concentrated in a few key products, making it vulnerable to declines in any one of them. Each factor has the potential to pressure earnings or compress the stock's valuation multiple.
Analyst consensus estimates AMGN will report consensus revenue of $39.6B (+6.2% year-over-year) and EPS of $19.45 (+35.7% year-over-year) for the upcoming fiscal year. The following year, analysts project $40.7B in revenue.
Amgen Inc. is expected to report its next earnings on approximately 2026-08-04. Consensus expects EPS of $5.55 and revenue of $9.4B. Over recent quarters, AMGN has beaten EPS estimates 92% of the time.
Amgen Inc. (AMGN) generated $8.6B in free cash flow over the trailing twelve months — a free cash flow margin of 23.1%. AMGN returns capital to shareholders through dividends (2.8% yield) and share repurchases ($0 TTM).