The company maintains minimal leverage with a debt-to-equity ratio of 0.02 and a robust current ratio of 4.26, but its equity base of $130.4M is entirely dependent on external capital infusions, as evidenced by a deepening accumulated deficit of -$138.0M.
Gyre Therapeutics, Inc. (GYRE) balance sheet — 22-year assets, liabilities & shareholders' equity history
| Metric | TTM | Dec'25 | Dec'24 | Dec'23 | Dec'22 | Dec'21 | Dec'20 | Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 | Dec'10 | Dec'09 | Dec'08 | Dec'07 | Dec'06 | Dec'05 | Dec'04 |
|---|
| Total Current Assets | 122.07M | 102.37M | 64.79M | 57.22M | 49.65M | 51.48M | 89.51M | 96.07M | 123.99M | 39.11M | 37.52M | 68.7M | 108.14M | 145.05M | 187.71M | 198.69M | 218.08M | 314.43M | 91.97M | 92.41M | 78.85M | 25.74M | 55.39M |
| Cash & Short-Term Investments | 74.8M | 52.42M | 26.67M | 33.51M | 25.18M | 46.85M | 79.35M | 76.86M | 120.13M | 32.44M | 17.06M | 32.5M | 107.39M | 143.78M | 184.93M | 195M | 214.02M | 111.07M | 88.36M | 87.04M | 54.19M | 24.85M | 53.08M |
| Cash Only | 43.29M | 37.07M | 11.81M | 33.51M | 25.18M | 44.35M | 30.36M | 15.37M | 31.21M | 14.47M | 10.26M | 29.1M | 56.43M | 54.48M | 82.24M | 107.28M | 165.85M | 83.91M | 51.2M | 53.4M | 41.74M | 24.85M | 53.08M |
| Short-Term Investments | 31.51M | 15.36M | 14.86M | 0 | 0 | 2.5M | 48.99M | 61.5M | 88.91M | 17.97M | 6.8M | 3.4M | 50.95M | 37.84M | 42.72M | 87.72M | 48.17M | 27.16M | 37.16M | 33.64M | 12.45M | 0 | 0 |
| Accounts Receivable | 28.25M | 36.95M | 29.15M | 16.84M | 15.61M | 1.82M | 3.31M | 15M | 0 | 24K | 31K | 492K | 141K | 278K | 1.38M | 218K | 838K | 201.8M | 2.07M | 4.2M | 23.37M | 118.16K | 484.56K |
| Days Sales Outstanding | 90.81 | 115.67 | 100.62 | 54.18 | 55.72 | 90.43 | 57.73 | - | - | 8.61 | 28.36 | 102.62 | 187.15 | 27.96 | 8.71 | 0.81 | 3.57 | 2.94K | 37.67 | 132.35 | 309.73 | 36.55 | 47.31 |
| Inventory | 11.43M | 10.17M | 6.34M | 4.28M | 6.12M | 898.12K | 0 | 0 | 0 | 5.31M | 19.47M | 33.79M | -141K | -999K | -2.78M | -218K | -838K | 1.56M | 100K | 140.41K | 173.69K | 41.94K | 102.64K |
| Days Inventory Outstanding | 560.41 | 685.45 | 595.52 | 337.05 | 466.21 | 42.74 | - | - | - | 150.84 | 673.22 | 2.07K | - | - | - | - | - | 825.08 | 48.73 | 71.64 | 138.65 | 31.83 | 188.78 |
| Other Current Assets | 7.6M | 2.83M | 1.44M | 1.04M | 2.37M | 1.91M | 6.84M | 4.2M | 3.86M | 1.33M | 958K | 1.91M | 756K | 0 | 0 | 3.69M | 4.06M | 0 | 0 | 1.04M | 0 | 0 | 0 |
| Total Non-Current Assets | 77.18M | 63.76M | 60.62M | 59.32M | 35.1M | 4.19M | 5.34M | 2.49M | 929K | 404K | 569K | 823K | 3.86M | 819K | 1.87M | 59.43M | 44.71M | 4.95M | 6.58M | 6.55M | 2.52M | 2.26M | 2.81M |
| Property, Plant & Equipment | 27.28M | 24.73M | 25.7M | 23.78M | 18.38M | 3.71M | 2.27M | 2.23M | 386K | 276K | 444K | 698K | 428K | 682K | 1.64M | 5.04M | 6.07M | 4.78M | 6.4M | 6.11M | 2.04M | 1.75M | 2.26M |
| Fixed Asset Turnover | 4.81x | 4.71x | 4.12x | 4.77x | 5.57x | 1.98x | 9.25x | - | 0.02x | 3.69x | 0.90x | 2.51x | 0.64x | 5.32x | 35.30x | 19.39x | 14.12x | 5.24x | 3.14x | 1.89x | 13.50x | 0.68x | 1.65x |
| Goodwill | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Intangible Assets | 4.53M | 4.73M | 1.71M | 1.7M | 1.86M | 3.26M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 97K | 115K | 132K | 149K | 167K | 184K | 437.44K | 475.21K | 512.97K | 484.56K |
| Long-Term Investments | 73.25M | 0 | 24.57M | 23.43M | 7.39M | 0 | 2.54M | 0 | 0 | 0 | 125K | 125K | 3.42M | 51.45M | 59.97M | 54.27M | 38.49M | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Current Assets | 36.09M | 27.43M | 3.03M | 5.72M | 7.47M | -2.79M | 528K | 257K | 543K | 128K | 0 | 0 | 12K | 137K | 231K | 54.27M | 38.49M | 0 | 0 | 0 | 0 | 0 | 0 |
| Total Assets | 199.25M | 166.13M | 125.41M | 116.54M | 84.75M | 55.66M | 94.85M | 98.55M | 124.92M | 39.51M | 38.09M | 69.52M | 112M | 145.87M | 189.58M | 258.13M | 262.79M | 319.38M | 98.55M | 98.96M | 81.37M | 28M | 58.2M |
| Asset Turnover | 0.70x | 0.70x | 0.84x | 0.97x | 1.21x | 0.13x | 0.22x | - | 0.00x | 0.03x | 0.01x | 0.03x | 0.00x | 0.02x | 0.31x | 0.38x | 0.33x | 0.08x | 0.20x | 0.12x | 0.34x | 0.04x | 0.06x |
| Asset Growth % | 115.1% | 32.48% | 7.61% | 37.5% | 52.26% | -41.31% | -3.76% | -21.11% | 216.15% | 3.74% | -45.21% | -37.93% | -23.22% | -23.05% | -26.56% | -1.77% | -17.72% | 224.07% | -0.42% | 21.63% | 190.59% | -51.89% | - |
| Total Current Liabilities | 28.66M | 18.29M | 19.52M | 20.05M | 12.24M | 14.16M | 17.8M | 28.9M | 4.8M | 8.74M | 21.96M | 37.76M | 2.91M | 10.98M | 11.35M | 78.61M | 98.66M | 101.16M | 13.79M | 15.2M | 8.95M | 5.21M | 5.31M |
| Accounts Payable | 1.24M | 124K | 108K | 355K | 122K | 6.42M | 5.93M | 4.28M | 1.25M | 747K | 837K | 939K | 405K | 1.3M | 2.06M | 3.49M | 4.72M | 1.27M | 1.5M | 2.3M | 1.98M | 1.17M | 1.85M |
| Days Payables Outstanding | 29.24 | 8.36 | 10.15 | 27.95 | 9.29 | 305.47 | 236.26 | 10.7K | 21.21 | 21.22 | 28.94 | 57.53 | 28.07 | 72.14 | - | - | - | 673.48 | 730.97 | 1.17K | 1.58K | 890.65 | 3.41K |
| Short-Term Debt | 0 | 0 | 0 | 0 | 0 | 1.98M | 663K | 483K | 0 | 5.08M | 19.4M | 33.74M | 0 | 853K | 851K | 1.24M | 1.71M | 1.44M | 1.39M | 918.6K | 593.33K | 783.89K | 1.11M |
| Deferred Revenue (Current) | 553K | 111K | 156K | 79K | 167K | 230K | 1.98M | 15M | 0 | 212K | 283K | 438K | 0 | -2.15M | 2.36M | 57.71M | 81.71M | 77.28M | 6.52M | 6.52M | 2.48M | 2.85M | 1.94M |
| Other Current Liabilities | 100K | 2.67M | 5.7M | 648K | 646K | 4.07M | 6.74M | 7.03M | 3.55M | 2.69M | 1.44M | 2.64M | 2.51M | 10.98M | 6.08M | 16.17M | 10.52M | 21.16M | 4.38M | 5.46M | 3.89M | 402.65K | 402.65K |
| Current Ratio | 4.26x | 5.60x | 3.32x | 2.85x | 4.06x | 3.63x | 5.03x | 3.32x | 25.83x | 4.48x | 1.71x | 1.82x | 37.11x | 13.21x | 16.54x | 2.53x | 2.21x | 3.11x | 6.67x | 6.08x | 8.81x | 4.94x | 10.43x |
| Quick Ratio | 3.86x | 5.04x | 2.99x | 2.64x | 3.56x | 3.57x | 5.03x | 3.32x | 25.83x | 3.87x | 0.82x | 0.92x | 37.16x | 13.30x | 16.78x | 2.53x | 2.22x | 3.09x | 6.66x | 6.07x | 8.79x | 4.93x | 10.41x |
| Cash Conversion Cycle | 621.98 | 792.76 | 685.99 | 363.28 | 512.63 | -172.3 | - | - | - | 138.22 | 672.63 | 2.12K | - | - | - | - | - | 3.09K | -644.57 | -967.36 | -1.13K | -822.27 | -3.17K |
| Total Non-Current Liabilities | 5.67M | 5.56M | 7.49M | 82.54M | 294K | 408K | 981K | 1.32M | 174K | 0 | 54K | 340K | 0 | 283K | 2.31M | 5.23M | 72.28M | 149.23M | 27.39M | 32.18M | 7.42M | 185.27M | 175.86M |
| Long-Term Debt | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 283K | 1.14M | 1.99M | 1.35M | 1.97M | 3.41M | 1.69M | 816.07K | 1.41M | 3.44M |
| Capital Lease Obligations | 2.95M | 303K | 885K | 199K | 121K | 408K | 981K | 1.32M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Deferred Tax Liabilities | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -67K | -109K | -30.35B | -6.6B | 0 | 0 |
| Other Non-Current Liabilities | 2.81M | 4.41M | 5.67M | 82.13M | 173K | 0 | 0 | 0 | 174K | 0 | 7K | 48K | 0 | 0 | 0 | 0 | 0 | 67K | 109K | 30.5M | 6.6M | 183.86M | 171.78M |
| Total Liabilities | 34.34M | 23.85M | 27M | 102.59M | 12.54M | 14.57M | 18.78M | 30.22M | 4.97M | 8.74M | 22.02M | 38.1M | 2.91M | 11.26M | 13.66M | 83.84M | 170.94M | 250.39M | 41.18M | 47.38M | 16.37M | 190.48M | 181.17M |
| Total Debt | 3.42M | 939K | 1.6M | 409K | 613K | 2.38M | 1.64M | 1.8M | 0 | 5.08M | 19.4M | 33.74M | 0 | 283K | 1.14M | 3.23M | 3.06M | 3.41M | 4.8M | 2.6M | 1.41M | 2.19M | 4.56M |
| Net Debt | -39.87M | -36.13M | -10.21M | -33.1M | -24.56M | -41.96M | -28.72M | -13.57M | -31.21M | -9.39M | 9.14M | 4.65M | -56.43M | -54.2M | -81.1M | -104.06M | -162.79M | -80.5M | -46.4M | -50.8M | -40.33M | -22.66M | -48.52M |
| Debt / Equity | 0.02x | 0.01x | 0.02x | 0.03x | 0.01x | 0.06x | 0.02x | 0.03x | - | 0.17x | 1.21x | 1.07x | - | 0.00x | 0.01x | 0.02x | 0.03x | 0.05x | 0.08x | 0.05x | 0.02x | - | - |
| Debt / EBITDA | -0.23x | 0.07x | 0.09x | - | 0.06x | - | - | - | - | - | - | - | - | - | - | - | 0.20x | - | - | - | 3.38x | - | - |
| Net Debt / EBITDA | 2.73x | -2.58x | -0.58x | - | -2.38x | - | - | - | - | - | - | - | - | - | - | - | -10.77x | - | - | - | -96.67x | - | - |
| Interest Coverage | - | - | - | - | - | - | - | - | - | - | - | -8.99x | -287.52x | -880.09x | -81.55x | -63.61x | 95.28x | -180.99x | -101.24x | - | - | - | - |
| Total Equity | 164.92M | 142.28M | 98.4M | 13.95M | 72.22M | 41.09M | 76.07M | 68.34M | 119.94M | 30.77M | 16.07M | 31.43M | 109.08M | 134.61M | 175.91M | 174.29M | 91.85M | 68.99M | 57.37M | 51.58M | 65M | -162.48M | -122.97M |
| Equity Growth % | 142.88% | 44.59% | 605.44% | -80.68% | 75.76% | -45.98% | 11.32% | -43.03% | 289.76% | 91.49% | -48.86% | -71.19% | -18.96% | -23.48% | 0.93% | 89.76% | 33.13% | 20.25% | 11.22% | -20.64% | 140% | -32.14% | - |
| Book Value per Share | 1.64 | 1.38 | 0.96 | 0.21 | 0.95 | 1.34 | 3.97 | 5.69 | 10.70 | 8.99 | 20.64 | 106.43 | 339.07 | 420.15 | 551.76 | 578.44 | 319.86 | 282.57 | 244.25 | 274.65 | 501.99 | -65122.69 | -58919.92 |
| Total Shareholders' Equity | 130.36M | 106.03M | 63.32M | -15.83M | 42.52M | 41.09M | 76.07M | 68.34M | 119.94M | 30.77M | 16.07M | 31.43M | 109.08M | 134.61M | 175.91M | 174.29M | 91.85M | 68.99M | 57.37M | 51.58M | 65M | -162.48M | -122.97M |
| Common Stock | 106K | 91 | 86K | 77K | 64K | 31K | 22K | 12K | 12K | 6K | 1K | 11K | 34K | 34K | 34K | 33K | 29K | 28K | 25K | 20.5K | 19.13K | 270 | 257 |
| Retained Earnings | -137.96M | -68.43M | -73.45M | -85.54M | 10.05M | -402.69M | -314.76M | -258.52M | -203.34M | -173.49M | -147.98M | -131.04M | -313.26M | -280.63M | -233.93M | -226.93M | -218.4M | -229.3M | -189.9M | -164.23M | -136.16M | -174.98M | -134.75M |
| Treasury Stock | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Accumulated OCI | 5.14M | 2.32M | 501K | 1.45M | -392K | 0 | 5K | 34K | -4K | 0 | -1K | 1K | 4K | 87K | 201K | 36K | 225K | 0 | 0 | 0 | -81.37B | 213.71K | 0 |
| Minority Interest | 34.56M | 36.25M | 35.08M | 29.78M | 29.7M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quick answers to the most common questions about buying GYRE stock.
As of 2025, Gyre Therapeutics, Inc. (GYRE) had total assets of $166.1M including $102.4M in current assets.
Gyre Therapeutics, Inc. (GYRE) carries total debt of $0.9M, offset by $52.4M in cash and short-term investments. Comparing total debt to cash helps evaluate the company's debt burden and net leverage.
Gyre Therapeutics, Inc. (GYRE) has total shareholders' equity (book value) of $106.0M ($1.38 book value per share). Book value represents the net worth of the company belonging to common stock holders.
Gyre Therapeutics, Inc. (GYRE) reported a current ratio of 5.60x. A current ratio above 1.0x indicates that the company has more current assets than current liabilities, suggesting sufficient short-term liquidity.
Key Metrics
Top Statement Risk
Sustained cash burn eroding equity base
Metrics are mathematically derived from official filings.
Asset Growth Driven by Equity Infusion
Total assets have expanded 63% from $122.0M in 2024Q1 to $199.3M in 2026Q2, a growth driven almost entirely by equity contributions rather than retained earnings, as evidenced by the concurrent deepening of the accumulated deficit to -$138.0M.
The balance sheet expansion appears to be a direct result of external capital raises, not operational success. This interpretation is supported by the fact that equity grew from $56.6M to $130.4M over the period while retained earnings deteriorated further into negative territory. The trajectory suggests the company is successfully funding its operations through equity markets, but the underlying business has yet to generate the profitability needed to self-sustain or grow the equity base organically.
Robust Liquidity Buffer Amid Operational Losses
Gyre's cash position surged to $43.3M in 2026Q2, representing a 189% increase from $15.0M in 2025Q1, providing a substantial liquidity buffer as indicated by a current ratio of 4.26.
The sharp increase in cash, particularly the $5.8M jump from 2026Q1 to 2026Q2, appears to be a recent capital infusion that has significantly bolstered the company's liquidity profile. This cash pile is critical given the prior analysis of sustained operating losses and negative free cash flow. The strong current ratio suggests ample short-term solvency, but the quality of this liquidity is entirely dependent on continued access to capital markets, as the core operations are not generating cash.
Equity Base Inflated by External Capital
Shareholders' equity has more than doubled from $56.6M in 2024Q1 to $130.4M in 2026Q2, yet this growth masks a deepening accumulated deficit of -$138.0M, indicating the equity increase is driven by paid-in capital, not operational profitability.
The composition of equity reveals a significant quality issue. The negative retained earnings balance, which has worsened over the period, confirms that cumulative losses have far exceeded any historical profits. The growth in total equity is therefore a function of investor funding, not business performance. This dynamic means the equity base is vulnerable to market sentiment and future capital raises, as the company cannot currently replenish equity through earnings.
Minimal Leverage Highlights Equity Dependence
Gyre maintains a negligible debt load with a debt-to-equity ratio of just 0.02 in 2026Q2, and total debt of only $3.4M against $43.3M in cash, suggesting a strategic choice to avoid leverage while funding operations through equity.
The near-zero leverage is a direct consequence of the company's operational profile and funding strategy. With persistent operating losses, taking on debt would likely be prohibitively expensive or unavailable, making equity the only viable funding source. This lack of debt provides financial flexibility and avoids refinancing risk, but it also means the company is fully exposed to equity dilution. The minimal debt appears to be a necessity-driven posture rather than a strategic choice from a position of strength.
Equity Base Vulnerable to Capital Market Access
The most significant balance sheet risk is the company's complete reliance on external equity financing to fund operations and grow assets, as the negative retained earnings of -$138.0M prove the business cannot self-fund.
While the headline balance sheet appears healthy with strong liquidity and low debt, this is an artificial construct. The core risk is that the entire financial structure depends on the company's ability to continuously raise equity capital. Any deterioration in market conditions, biotech sentiment, or company-specific milestones could severely impair this access. The negative retained earnings are a stark indicator that the current business model is not economically viable on a standalone basis, making the balance sheet's strength contingent on factors outside management's direct control.