Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in GYRE held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | VANGUARD CAPITAL MANAGEMENT LLC | 984K | $6.9M | — | 1.015% | 0.00% |
| 2 | BlackRock, Inc. | 759K | $5.3M | +5.3% | 0.782% | 0.00% |
| 3 | GEODE CAPITAL MANAGEMENT, LLC | 431K | $3.0M | +1.9% | 0.445% | 0.00% |
| 4 | STATE STREET CORP | 216K | $1.5M | +7.0% | 0.223% | 0.00% |
| 5 | SBI Securities Co., Ltd. | 171K | $1.2M | +4.9% | 0.176% | 0.03% |
| 6 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 165K | $1.2M | -2.3% | 0.170% | 0.00% |
| 7 | VANGUARD FIDUCIARY TRUST CO | 138K | $960K | — | 0.142% | 0.00% |
| 8 | NORTHERN TRUST CORP | 134K | $933K | +3.9% | 0.138% | 0.00% |
| 9 | GOLDMAN SACHS GROUP INC | 73K | $510K | +135.1% | 0.075% | 0.00% |
| 10 | VANGUARD PORTFOLIO MANAGEMENT LLC | 70K | $487K | — | 0.072% | 0.00% |
| 11 | Bank of New York Mellon Corp | 43K | $301K | +4.7% | 0.044% | 0.00% |
| 12 | DIMENSIONAL FUND ADVISORS LP | 25K | $176K | +131.8% | 0.026% | 0.00% |
| 13 | ALLIANCEBERNSTEIN L.P. | 22K | $154K | 0.0% | 0.022% | 0.00% |
| 14 | STRS OHIO | 21K | $147K | 0.0% | 0.022% | 0.00% |
| 15 | UBS Group AG | 21K | $147K | +120.0% | 0.022% | 0.00% |
| 16 | FMR LLC | 19K | $130K | +81.7% | 0.019% | 0.00% |
| 17 | Brevan Howard Capital Management LP | 14K | $96K | — | 0.014% | 0.00% |
| 18 | RHUMBLINE ADVISERS | 13K | $91K | -6.5% | 0.013% | 0.00% |
| 19 | DEUTSCHE BANK AG\ | 11K | $74K | 0.0% | 0.011% | 0.00% |
| 20 | BANK OF AMERICA CORP /DE/ | 11K | $73K | +8.0% | 0.011% | 0.00% |
| 21 | Vanguard Global Advisers, LLC | 10K | $70K | — | 0.010% | 0.00% |
| 22 | MORGAN STANLEY | 9K | $60K | -84.1% | 0.009% | 0.00% |
| 23 | Tower Research Capital LLC (TRC) | 6K | $40K | +177.5% | 0.006% | 0.00% |
| 24 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 6K | $39K | +2.5% | 0.006% | 0.00% |
| 25 | ROYAL BANK OF CANADA | 6K | $39K | -56.1% | 0.006% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in GYRE — a direct measure of their conviction.
Filings activity in GYRE during Q1 2026, grouped by how each filer changed its position.
Institutions that opened a new GYRE position in Q1 2026
Institutions that fully closed their GYRE position in Q1 2026
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 54 | +23% | 4.12% | +0.02 pp | $24M | +0.5% |
| Q4 2025 | 44 | 8.3% | 4.10% | +0.09 pp | $24M | +2.3% |
| Q3 2025 | 48 | +0.0% | 4.01% | 0.31 pp | $23M | 7.3% |
| Q2 2025 | 48 | +4.3% | 4.32% | +0.83 pp | $25M | +24% |
| Q1 2025 | 46 | +12% | 3.49% | 0.24 pp | $20M | 6.6% |
| Q4 2024 | 41 | +11% | 3.73% | +0.24 pp | $21M | +7.1% |
| Q3 2024 | 37 | +19% | 3.49% | +0.91 pp | $20M | +35% |
| Q2 2024 | 31 | — | 2.58% | — | $15M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying GYRE stock.
Based on Q1 2026 13F filings, institutional ownership of Gyre Therapeutics, Inc. stands at 4.1%, held across 54 reporting institutions.
VANGUARD CAPITAL MANAGEMENT LLC is the largest reported institutional holder of GYRE, with approximately 984,204 shares worth $0.01B as of Q1 2026.
No marquee "smart money" managers (Berkshire, Burry, ARK, Tiger Global, Pershing Square, Baupost, etc.) currently appear among the top 25 institutional holders of GYRE.
Our composite Smart Money Score for GYRE is 45 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
14 institutions opened new positions in GYRE during Q1 2026, while 4 fully exited. 14 added to existing positions and 22 trimmed.
GYRE institutional ownership rose by 0.02 percentage points quarter-over-quarter, with a net change of +10 holders.
The top 10 institutions account for 92.4% of all reported 13F value in GYRE, and the top 25 account for 99.4%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Gyre Therapeutics, Inc. (GYRE) Institutional Ownership