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INSM logoInsmed Incorporated (INSM) Earnings History

Annual and quarterly earnings data from 1999 to 2025

TTM Net Income
-$1.28B
Net Loss
TTM EPS
$-5.98
Diluted
YoY EPS Growth
-15.1%
Declining
Net Margin
-210.5%
Profitability
Operating Margin-194.0%
Gross Margin79.4%
ROE-249.3%
ROA-59.5%
Highest Annual Net Income$118M (2009)
Highest Quarterly EPS$9.60 (Q1 2009)
Consecutive Profitable Years0 years
Q4 2025
Net Income-$328M
EPS$-1.54
QoQ Growth+11.2%Strong

Loading earnings history...

INSM EPS Growth (CAGR)

Compound annual growth rate of diluted earnings per share

1-Year
N/A
N/M
3-Year
N/A
N/M
5-Year
N/A
N/M
10-Year
N/A
N/M

CAGR (Compound Annual Growth Rate) shows the annualized growth rate of EPS over the specified period. A higher CAGR indicates stronger earnings momentum.

INSM Profitability Analysis

Margin trends over time

View revenue breakdown →
YearGross MarginOperating MarginNet Margin
202579.4%-194.0%-210.5%
202476.4%-241.5%-251.2%
202378.5%-232.5%-245.6%
202277.5%-186.4%-196.3%
202176.6%-199.0%-230.6%
Gross Margin = Gross Profit ÷ Revenue
Operating Margin = Operating Income ÷ Revenue
Net Margin = Net Income ÷ Revenue

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Insmed Incorporated (INSM) Earnings Overview

As of May 8, 2026, Insmed Incorporated (INSM) reported trailing twelve-month net income of -$1.28B, reflecting -15.1% year-over-year growth. The company earned $-5.98 per diluted share over the past four quarters, with a net profit margin of -210.5%.

Looking at the long-term picture, INSM's historical earnings data spans multiple years. The company achieved its highest annual net income of $118M in fiscal 2009.

Insmed Incorporated is currently reporting a net loss, though operating performance should be evaluated in the context of growth investments and industry dynamics View revenue history →

Compared to peers including RARE (-$609M net income, -85.4% margin), ALNY ($577M net income, 8.4% margin), BMRN ($269M net income, 10.8% margin), INSM has room to improve margins relative to the peer group. Compare INSM vs RARE →

INSM Earnings vs Peers

Earnings metrics vs comparable public companies

CompanyTTM Net IncomeTTM EPSNet MarginROEYoY GrowthCompare
INSM logoINSMCurrent
-$1.3B$-5.98-210.5%-249.3%-15.1%—
RARE logoRARE
-$609M$-6.06-85.4%-607.5%+7.3%
ALNY logoALNY
$577M$4.188.4%73.3%+206.9%
BMRN logoBMRN
$269M$1.3610.8%5.9%-18.6%
SRPT logoSRPT
$65M$0.53-32.5%-53.5%-404.7%
IONS logoIONS
-$327M$-1.98-40.4%-70.7%+21.7%
Best in group
Lowest in group

INSM Historical Earnings Data (1999–2025)

27 years
Fiscal Year Net Income YoY % Operating Income EPS (Diluted) Net Margin Op. Margin
2025-$1.28B-39.7%-$1.18B$-6.41-210.5%-194.0%
2024-$914M-21.9%-$878M$-5.57-251.2%-241.5%
2023-$750M-55.7%-$710M$-5.34-245.6%-232.5%
2022-$482M-10.8%-$457M$-3.91-196.3%-186.4%
2021-$435M-47.8%-$375M$-3.88-230.6%-199.0%
2020-$294M-15.6%-$265M$-3.01-178.9%-161.3%
2019-$254M+21.6%-$235M$-3.01-186.4%-172.4%
2018-$324M-68.3%-$307M$-4.22-3297.2%-3124.9%
2017-$193M-9.3%-$189M$-2.89--
2016-$176M-49.2%-$173M$-2.85--

Full INSM Stock Analysis

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Compare INSM vs DBVT

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INSM — Frequently Asked Questions

Quick answers to the most common questions about buying INSM stock.

Is INSM growing earnings?

INSM EPS fell to $-5.98, with earnings declining -15.1%. This contrasts with the 5-year CAGR of N/A. TTM net income dropped to $-1.3B.

What are INSM's profit margins?

Insmed Incorporated net margin is -210.5%, with operating margin at -194.0%. Below-average margins reflect competitive or cost pressures.

How consistent are INSM's earnings?

INSM earnings data spans 1999-2025. The declining earnings trend is -15.1% YoY. Historical data enables comparison across business cycles.

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INSM Earnings Over Time (2014–2025)

Net income and EPS trends