Insmed Incorporated (INSM) Financial Ratios
27 years of historical data (1999–2025) · Healthcare · Medical - Pharmaceuticals
EV/EBITDA
N/A
—
5yr avg: N/A
P/FCF
N/A
—
5yr avg: N/A
P/B Ratio
↑
27.70
↓-12% vs avg
5yr avg: 31.35
30Y Low0.4·High50.3
ROE
↓
-249.3%
-12% vs avg
5yr avg: -222.3%
30Y Low-461%·High195%
Debt/EBITDA
N/A
—
5yr avg: N/A
Percentile shows where the current value sits in 30-year historical distribution. Sparklines show 5-year trend.
INSM Valuation Multiples
Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow
Insmed Incorporated currently has a negative P/E ratio, indicating the company is operating at a loss on a trailing-twelve-month basis.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Market Cap | $20.8B | $37.2B | $11.3B | $4.4B | $2.5B | $3.1B | $3.2B | $2.0B | $1.0B | $2.1B | $819M |
| Enterprise Value | $21.0B | $37.4B | $12.1B | $5.1B | $2.6B | $2.9B | $3.1B | $1.9B | $830M | $1.8B | $711M |
| P/E Ratio → | -14.95 | — | — | — | — | — | — | — | — | — | — |
| P/S Ratio | 34.24 | 61.31 | 31.14 | 14.26 | 10.02 | 16.20 | 19.76 | 14.80 | 102.57 | — | — |
| P/B Ratio | 27.70 | 50.31 | 39.69 | — | 27.95 | 7.44 | 11.78 | 7.72 | 4.84 | 5.75 | 5.30 |
| P/FCF | — | — | — | — | — | — | — | — | — | — | — |
| P/OCF | — | — | — | — | — | — | — | — | — | — | — |
P/E links to full P/E history page with 30-year chart
INSM EV Ratios
Enterprise-value multiples — capital-structure-neutral measures of total business value
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| EV / Revenue | — | 61.74 | 33.23 | 16.62 | 10.44 | 15.65 | 18.98 | 14.13 | 84.42 | — | — |
| EV / EBITDA | — | — | — | — | — | — | — | — | — | — | — |
| EV / EBIT | — | — | — | — | — | — | — | — | — | — | — |
| EV / FCF | — | — | — | — | — | — | — | — | — | — | — |
INSM Profitability
Margins and return-on-capital ratios measuring operating efficiency
Insmed Incorporated earns an operating margin of -194.0%. Operating margins have expanded from -232.5% to -194.0% over the past 3 years, signaling improving operational efficiency. A negative ROE of -249.3% indicates the company is currently destroying shareholder equity.
Margins
Full margin charts and quarterly trend are on the Earnings History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 79.4% | 79.4% | 76.4% | 78.5% | 77.5% | 76.6% | 75.7% | 82.3% | 75.4% | — | — |
| Operating Margin | -194.0% | -194.0% | -241.5% | -232.5% | -186.4% | -199.0% | -161.3% | -172.4% | -3124.9% | — | — |
| Net Profit Margin | -210.5% | -210.5% | -251.2% | -245.6% | -196.3% | -230.6% | -178.9% | -186.4% | -3297.2% | — | — |
Return on Capital
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -249.3% | -249.3% | -320.2% | — | -193.2% | -126.7% | -109.4% | -108.2% | -113.9% | -74.7% | -75.6% |
| ROA | -59.5% | -59.5% | -54.5% | -50.2% | -33.2% | -42.6% | -38.2% | -37.8% | -60.8% | -55.0% | -59.3% |
| ROIC | -86.5% | -86.5% | -91.9% | -183.1% | -137.8% | -124.0% | -124.6% | -175.5% | -706.9% | -345.0% | -258.4% |
| ROCE | -66.8% | -66.8% | -62.0% | -55.2% | -35.5% | -42.0% | -39.8% | -39.8% | -65.2% | -60.2% | -63.7% |
INSM Leverage & Debt
Solvency and debt-coverage ratios — lower is generally safer
Net debt stands at $258M ($768M total debt minus $510M cash).
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 1.04 | 1.04 | 4.60 | — | 13.39 | 1.49 | 1.47 | 1.52 | 1.52 | 0.15 | 0.35 |
| Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — |
| Net Debt / Equity | — | 0.35 | 2.66 | — | 1.18 | -0.25 | -0.46 | -0.35 | -0.86 | -0.90 | -0.70 |
| Net Debt / EBITDA | — | — | — | — | — | — | — | — | — | — | — |
| Debt / FCF | — | — | — | — | — | — | — | — | — | — | — |
| Interest Coverage | -14.18 | -14.18 | -9.77 | -8.21 | -17.31 | -9.83 | -8.95 | -8.20 | -11.78 | -31.56 | -49.36 |
INSM Liquidity & Efficiency
Short-term solvency ratios and asset-utilisation metrics
Insmed Incorporated's current ratio of 3.83x is well above the 1.0 safety threshold, indicating strong short-term liquidity with ample room to cover current liabilities. The current ratio has declined from 4.12x to 3.83x over the past 3 years.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 3.83 | 3.83 | 5.45 | 4.12 | 6.69 | 6.19 | 5.24 | 6.51 | 6.51 | 8.72 | 6.02 |
| Quick Ratio | 3.54 | 3.54 | 5.12 | 3.75 | 6.33 | 5.70 | 4.83 | 6.18 | 6.42 | 8.72 | 6.02 |
| Cash Ratio | 3.05 | 3.05 | 4.82 | 3.46 | 6.04 | 5.30 | 4.48 | 5.72 | 6.21 | 8.54 | 5.81 |
| Asset Turnover | — | 0.27 | 0.18 | 0.23 | 0.15 | 0.15 | 0.21 | 0.18 | 0.02 | — | — |
| Inventory Turnover | 0.95 | 0.95 | 0.87 | 0.79 | 0.79 | 0.66 | 0.80 | 0.86 | 0.34 | — | — |
| Days Sales Outstanding | — | 84.78 | 52.20 | 49.26 | 44.20 | 47.16 | 36.77 | 51.44 | 204.67 | — | — |
INSM Shareholder Yields
Earnings, FCF, buyback, and dividend yields — total returns to shareholders
Insmed Incorporated does not currently pay a dividend and has no material buyback yield, reinvesting earnings back into the business.
Dividends
Full dividend history and growth charts are on the Dividend History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Dividend Yield | — | — | — | — | — | — | — | — | — | — | — |
| Payout Ratio | — | — | — | — | — | — | — | — | — | — | — |
Total Shareholder Return Metrics
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Earnings Yield | — | — | — | — | — | — | — | — | — | — | — |
| FCF Yield | — | — | — | — | — | — | — | — | — | — | — |
| Buyback Yield | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
| Total Shareholder Yield | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
| Shares Outstanding | — | $214M | $164M | $140M | $123M | $112M | $98M | $85M | $77M | $67M | $62M |
Peer Comparison
Compare INSM with 10 similar companies in its peer group
| Company | Market Cap | P/E | EV/EBITDA | P/FCF | Gross Margin | Op Margin | ROE | ROIC | Debt/EBITDA |
|---|---|---|---|---|---|---|---|---|---|
 INSMYou | $21B | -14.9 | — | — | 79.4% | -194.0% | -249.3% | -86.5% | — |
 RARE | $3B | -4.7 | — | — | 83.8% | -79.5% | -607.5% | -89.4% | — |
 ALNY | $37B | 119.4 | 65.9 | 79.7 | 81.8% | 13.5% | 73.3% | 33.4% | 2.3 |
 BMRN | $11B | 30.4 | 16.1 | 14.5 | 77.1% | 16.6% | 5.9% | 7.4% | 1.0 |
 SRPT | $2B | -2.5 | — | — | 59.9% | -29.9% | -53.5% | -31.4% | — |
 IONS | $12B | -31.1 | — | — | 98.3% | -40.5% | -70.7% | -12.8% | — |
 ACAD | $4B | 9.4 | 25.7 | 35.2 | 91.7% | 9.8% | 39.9% | 10.0% | 0.4 |
 PRAX | $8B | -20.9 | — | — | — | — | -45.8% | -65.0% | — |
 ARWR | $12B | -6706.6 | 95.4 | 73.5 | 100.0% | 11.9% | -0.5% | 9.3% | 3.0 |
 KRYS | $10B | 50.9 | 58.2 | 54.3 | 92.6% | 41.5% | 18.9% | 18.0% | 0.1 |
 FOLD | $5B | -164.8 | 114.9 | 152.4 | 87.3% | 5.4% | -11.6% | 5.3% | 11.5 |
| Healthcare Median | — | 22.1 | 14.2 | 18.5 | 63.9% | -4.3% | -32.6% | -11.6% | 3.2 |
Peer selection based on competitive and market overlap. Compare multiple stocks →
Download Financial Ratios Data
Includes 30+ ratios · 27 years · Updated daily
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INSM — Frequently Asked Questions
Quick answers to the most common questions about buying INSM stock.
What is Insmed Incorporated's P/E ratio?
Insmed Incorporated's current P/E ratio is -14.9x. The historical average is 0.8x.
What is Insmed Incorporated's ROE?
Insmed Incorporated's return on equity (ROE) is -249.3%. The historical average is -134.5%.
Is INSM stock overvalued?
Based on historical data, Insmed Incorporated is trading at a P/E of -14.9x. Compare with industry peers and growth rates for a complete picture.
What are Insmed Incorporated's profit margins?
Insmed Incorporated has 79.4% gross margin and -194.0% operating margin.