Ranked by reported Q2 2026 13F market value
Share of total reported institutional value in INSM held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 16.1M | $1.72B | +22.7% | 7.448% | 0.07% |
| 2 | BlackRock, Inc. | 15.8M | $1.69B | -5.2% | 7.293% | 0.03% |
| 3 | VANGUARD PORTFOLIO MANAGEMENT LLC | 10.4M | $1.11B | +0.4% | 4.802% | 0.05% |
| 4 | JPMORGAN CHASE & CO | 10.4M | $1.09B | -56.8% | 4.811% | 0.06% |
| 5 | VANGUARD CAPITAL MANAGEMENT LLC | 9.8M | $1.04B | +1.5% | 4.517% | 0.02% |
| 6 | BAKER BROS. ADVISORS LP | 8.8M | $937.8M | +18.5% | 4.058% | 4.70% |
| 7 | Capital International Investors | 8.2M | $878.3M | +47.2% | 3.801% | 0.18% |
| 8 | Darwin Global Management, Ltd. | 6.4M | $673.6M | -61.7% | 2.967% | 17.91% |
| 9 | AMERIPRISE FINANCIAL INC | 6.2M | $658.9M | +102.1% | 2.851% | 0.13% |
| 10 | Orbis Allan Gray Ltd | 6.1M | $647.9M | +224.5% | 2.803% | 2.23% |
| 11 | STATE STREET CORP | 6.1M | $645.3M | +9.0% | 2.792% | 0.01% |
| 12 | D. E. Shaw & Co., Inc. | 5.9M | $633.1M | +5.2% | 2.740% | 0.30% |
| 13 | Artisan Partners Limited Partnership | 5.4M | $580.2M | -16.6% | 2.511% | 0.92% |
| 14 | RTW INVESTMENTS, LP | 4.8M | $516.3M | 0.0% | 2.234% | 4.41% |
| 15 | GEODE CAPITAL MANAGEMENT, LLC | 4.2M | $448.8M | -5.2% | 1.947% | 0.02% |
| 16 | NORGES BANK | 3.4M | $360.1M | — | 1.558% | 0.04% |
| 17 | CITADEL ADVISORS LLC | 3.2M | $339.9M | +22.0% | 1.471% | 0.02% |
| 18 | MILLENNIUM MANAGEMENT LLC | 2.9M | $312.2M | +126.1% | 1.351% | 0.11% |
| 19 | Jupiter Topco LLC | 2.6M | $277.8M | — | 1.202% | 0.11% |
| 20 | UBS Group AG | 2.6M | $275.8M | +48.9% | 1.193% | 0.04% |
| 21 | FRANKLIN RESOURCES INC | 2.3M | $242.4M | -13.1% | 1.049% | 0.05% |
| 22 | GOLDMAN SACHS GROUP INC | 2.3M | $241.1M | +139.9% | 1.043% | 0.02% |
| 23 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 2.2M | $230.7M | +100.6% | 0.998% | 0.02% |
| 24 | MAVERICK CAPITAL LTD | 2.2M | $229.3M | — | 0.992% | 2.03% |
| 25 | Qube Research & Technologies Ltd | 1.7M | $179.4M | +1032.8% | 0.776% | 0.17% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in INSM — a direct measure of their conviction.
Filings activity in INSM during Q2 2026, grouped by how each filer changed its position.
Institutions that opened a new INSM position in Q2 2026
Institutions that fully closed their INSM position in Q2 2026
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q2 2026 | 671 | 0.4% | 106.96% | +3.60 pp | $23.53B | 32% |
| Q1 2026 | 674 | +0.3% | 103.36% | 0.35 pp | $34.73B | 5.4% |
| Q4 2025 | 672 | +20% | 103.71% | 0.02 pp | $36.70B | +24% |
| Q3 2025 | 559 | +11% | 103.73% | +2.34 pp | $29.53B | +52% |
| Q2 2025 | 502 | +16% | 101.39% | 8.55 pp | $19.41B | +44% |
| Q1 2025 | 432 | +3.1% | 109.94% | +1.36 pp | $13.49B | +14% |
| Q4 2024 | 419 | +5.0% | 108.58% | +2.76 pp | $11.82B | 2.7% |
| Q3 2024 | 399 | — | 105.82% | — | $12.15B | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying INSM stock.
Based on Q2 2026 13F filings, institutional ownership of Insmed Incorporated stands at 107.0%, held across 671 reporting institutions.
FMR LLC is the largest reported institutional holder of INSM, with approximately 16,143,583 shares worth $1.72B as of Q2 2026.
Yes — 3 widely-followed marquee investors appear among the top 25 institutional holders of INSM, including CITADEL ADVISORS LLC, MILLENNIUM MANAGEMENT LLC, SUSQUEHANNA INTERNATIONAL GROUP, LLP.
Our composite Smart Money Score for INSM is 66 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
104 institutions opened new positions in INSM during Q2 2026, while 114 fully exited. 110 added to existing positions and 438 trimmed.
INSM institutional ownership rose by 3.60 percentage points quarter-over-quarter, with a net change of -3 holders.
The top 10 institutions account for 44.4% of all reported 13F value in INSM, and the top 25 account for 67.8%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Insmed Incorporated (INSM) Institutional Ownership