Karyopharm Therapeutics Inc. (KPTI) quarterly income statement — complete revenue, gross profit & net income history
Karyopharm Therapeutics Inc. (KPTI) annual income statement — 15-year revenue, gross profit & net income history
| Metric | Q2'26 | Q1'26 | Q4'25 | Q3'25 | Q2'25 | Q1'25 | Q4'24 | Q3'24 | Q2'24 | Q1'24 | Q4'23 | Q3'23 | Q2'23 | Q1'23 | Q4'22 | Q3'22 | Q2'22 | Q1'22 | Q4'21 | Q3'21 |
|---|
| Sales/Revenue | 33.43M | 35.07M | 34.08M | 44.04M | 37.93M | 30.02M | 30.54M | 38.78M | 42.79M | 33.13M | 33.75M | 36.01M | 37.58M | 38.7M | 33.58M | 36.15M | 39.68M | 47.67M | 126.27M | 37.69M |
| Revenue Growth % | -11.86% | 16.83% | 11.58% | 13.57% | -11.35% | -9.39% | -9.5% | 7.7% | 13.86% | -14.4% | 0.5% | -0.38% | -5.29% | -18.82% | -73.41% | -4.1% | 75.56% | 104.94% | 259.74% | 76.67% |
| Cost of Goods Sold | 1.08M | 1.36M | 1.48M | 2.11M | 1.05M | 1.3M | 1.33M | 1.3M | 1.56M | 2M | 1.56M | 911K | 1.19M | 1.35M | 1.87M | 980K | 939K | 1.43M | 742K | 589K |
| COGS % of Revenue | 3.25% | 3.87% | 4.35% | 4.8% | 2.77% | 4.33% | 4.36% | 3.35% | 3.64% | 6.03% | 4.63% | 2.53% | 3.18% | 3.49% | 5.56% | 2.71% | 2.37% | 2.99% | 0.59% | 1.56% |
| Gross Profit | 32.35M | 33.71M | 32.59M | 41.93M | 36.88M | 28.71M | 29.21M | 37.48M | 41.23M | 31.13M | 32.18M | 35.1M | 36.38M | 37.35M | 31.71M | 35.16M | 38.74M | 46.24M | 125.53M | 37.1M |
| Gross Margin % | 96.75% | 96.13% | 95.65% | 95.2% | 97.23% | 95.67% | 95.64% | 96.65% | 96.36% | 93.97% | 95.37% | 97.47% | 96.82% | 96.51% | 94.44% | 97.29% | 97.63% | 97.01% | 99.41% | 98.44% |
| Gross Profit Growth % | -12.29% | 17.4% | 11.58% | 11.87% | -10.56% | -7.76% | -9.24% | 6.8% | 13.32% | -16.65% | 1.49% | -0.19% | -6.08% | -19.24% | -74.74% | -5.22% | 80.5% | 107.12% | 268.68% | 77.55% |
| Operating Expenses | 54.87M | 60.47M | 50.44M | 57.15M | 61.27M | 61.97M | 60.49M | 63.77M | 69.35M | 64.89M | 69.99M | 66.36M | 65.96M | 68.25M | 65.58M | 66M | 81.65M | 80.83M | 78.56M | 80.91M |
| OpEx % of Revenue | 164.13% | 172.44% | 148.01% | 129.76% | 161.53% | 206.46% | 198.06% | 164.42% | 162.09% | 195.89% | 207.4% | 184.28% | 175.52% | 176.36% | 195.3% | 182.61% | 205.77% | 169.56% | 62.22% | 214.68% |
| Selling, General & Admin | 25.92M | 26.68M | 22.77M | 26.61M | 28.48M | 27.35M | 27.19M | 27.63M | 31.07M | 29.55M | 30.69M | 30.8M | 34.48M | 35.91M | 34.65M | 34.65M | 37.34M | 38.77M | 34.56M | 35.1M |
| SG&A % of Revenue | 77.52% | 76.1% | 66.82% | 60.41% | 75.08% | 91.13% | 89.02% | 71.25% | 72.62% | 89.2% | 90.94% | 85.55% | 91.76% | 92.79% | 103.18% | 95.85% | 94.1% | 81.33% | 27.37% | 93.14% |
| Research & Development | 29.95M | 33.78M | 27.67M | 30.54M | 32.79M | 34.62M | 33.3M | 36.13M | 38.28M | 35.34M | 39.3M | 35.55M | 31.48M | 32.34M | 30.93M | 31.36M | 44.31M | 42.06M | 44M | 45.81M |
| R&D % of Revenue | 89.57% | 96.35% | 81.18% | 69.35% | 86.45% | 115.34% | 109.04% | 93.17% | 89.47% | 106.68% | 116.47% | 98.73% | 83.76% | 83.57% | 92.11% | 86.76% | 111.67% | 88.24% | 34.85% | 121.54% |
| Other Operating Expenses | -988K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Operating Income | -22.53M | -26.76M | -17.84M | -15.22M | -24.39M | -33.26M | -31.28M | -26.28M | -28.12M | -33.76M | -37.81M | -31.26M | -29.57M | -30.9M | -33.87M | -30.84M | -42.91M | -34.59M | 46.96M | -43.81M |
| Operating Margin % | -67.38% | -76.31% | -52.36% | -34.56% | -64.3% | -110.8% | -102.42% | -67.77% | -65.72% | -101.91% | -112.03% | -86.81% | -78.7% | -79.85% | -100.86% | -85.32% | -108.14% | -72.55% | 37.19% | -116.25% |
| Operating Income Growth % | 7.63% | 19.53% | 42.96% | 42.09% | 13.28% | 1.49% | 17.26% | 15.92% | 4.91% | -9.26% | -11.63% | -1.37% | 31.08% | 10.66% | -172.12% | 29.61% | 12.52% | 33.96% | 226.7% | 7% |
| EBITDA | -22.53M | -26.75M | -17.82M | -15.1M | -24.31M | -33.18M | -31.2M | -26.2M | -28.03M | -33.67M | -37.73M | -31.18M | -29.49M | -30.61M | -33.76M | -30.66M | -42.76M | -34.41M | 47.1M | -43.63M |
| EBITDA Margin % | -67.39% | -76.28% | -52.3% | -34.28% | -64.09% | -110.54% | -102.15% | -67.56% | -65.51% | -101.65% | -111.81% | -86.59% | -78.47% | -79.1% | -100.52% | -84.82% | -107.76% | -72.18% | 37.3% | -115.75% |
| EBITDA Growth % | 7.32% | 19.38% | 42.87% | 42.37% | 13.27% | 1.47% | 17.31% | 15.97% | 4.95% | -10.01% | -11.78% | -1.71% | 31.03% | 11.04% | -171.67% | 29.73% | 12.41% | 34% | 227.96% | 6.93% |
| D&A (Non-Cash Add-back) | -3K | 12K | 19K | 121K | 78K | 78K | 81K | 83K | 91K | 85K | 77K | 80K | 83K | 290K | 113K | 182K | 149K | 177K | 139K | 186K |
| EBIT | -53.88M | -9.84M | -89.65M | -22.64M | -25.98M | -12.43M | -19.68M | -20.66M | 32.81M | -31.41M | -35.5M | -28.42M | -26.72M | -28.31M | -32.55M | -30.16M | -42.63M | -34.59M | 46.54M | -43.7M |
| Net Interest Income | -12.42M | -12.04M | -12.01M | -10.46M | -10.62M | -9.99M | -9.72M | -9.55M | -7.02M | -3.73M | -3.69M | -3.32M | -2.96M | -2.91M | -4.55M | -5.46M | -6.02M | -6.61M | -7.88M | -7.91M |
| Interest Income | 722K | 511K | 607K | 553K | 613K | 1M | 1.48M | 1.83M | 1.93M | 2.16M | 2.52M | 2.75M | 2.82M | 2.85M | 1.33M | 658K | 293K | 74K | 55K | 98K |
| Interest Expense | 13.14M | 12.55M | 12.62M | 11.01M | 11.23M | 10.99M | 11.2M | 11.38M | 8.95M | 5.88M | 6.21M | 6.07M | 5.78M | 5.76M | 5.88M | 6.11M | 6.31M | 6.68M | 7.94M | 8.01M |
| Other Income/Expense | -44.5M | 4.37M | -84.42M | -17.87M | -12.82M | 9.83M | 392K | -5.76M | 51.98M | -3.53M | -3.9M | -3.23M | -2.93M | -3.17M | -4.56M | -5.44M | -6.03M | -6.68M | -8.36M | -7.89M |
| Pretax Income | -67.02M | -22.39M | -102.27M | -33.09M | -37.21M | -23.43M | -30.89M | -32.04M | 23.86M | -37.29M | -41.71M | -34.49M | -32.5M | -34.07M | -38.43M | -36.28M | -48.94M | -41.27M | 38.6M | -51.71M |
| Pretax Margin % | -200.48% | -63.85% | -300.08% | -75.14% | -98.11% | -78.05% | -101.14% | -82.62% | 55.76% | -112.57% | -123.59% | -95.79% | -86.49% | -88.05% | -114.45% | -100.37% | -123.34% | -86.57% | 30.57% | -137.19% |
| Income Tax | 0 | 1K | -67K | 34K | 40K | 36K | -109K | 28K | 67K | 71K | 130K | 12K | 127K | 54K | 73K | 45K | 121K | 130K | -121K | 106K |
| Effective Tax Rate % | 0% | -0% | 0.07% | -0.1% | -0.11% | -0.15% | 0.35% | -0.09% | 0.28% | -0.19% | -0.31% | -0.03% | -0.39% | -0.16% | -0.19% | -0.12% | -0.25% | -0.32% | -0.31% | -0.21% |
| Net Income | -67.02M | -22.39M | -102.2M | -33.13M | -37.25M | -23.46M | -30.78M | -32.07M | 23.79M | -37.36M | -41.84M | -34.51M | -32.63M | -34.13M | -38.51M | -36.32M | -49.06M | -41.4M | 38.72M | -51.81M |
| Net Margin % | -200.48% | -63.86% | -299.89% | -75.21% | -98.22% | -78.17% | -100.78% | -82.7% | 55.61% | -112.79% | -123.97% | -95.83% | -86.83% | -88.19% | -114.67% | -100.5% | -123.65% | -86.84% | 30.66% | -137.47% |
| Net Income Growth % | -79.92% | 4.56% | -232.03% | -3.29% | -256.57% | 37.2% | 26.43% | 7.05% | 172.91% | -9.48% | -8.65% | 5% | 33.49% | 17.57% | -199.45% | 29.89% | 8.44% | 27.89% | 189.17% | 3.15% |
| Net Income (Continuing) | -67.02M | -22.39M | -102.2M | -33.13M | -37.25M | -23.46M | -30.78M | -32.07M | 23.79M | -37.36M | -41.84M | -34.51M | -32.63M | -34.13M | -38.51M | -36.32M | -49.06M | -41.4M | 38.72M | -51.81M |
| Discontinued Operations | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| EPS (Diluted) | -2.32 | -1.24 | -5.69 | -3.82 | -4.32 | -2.77 | 2.81 | -3.85 | -2.97 | -4.85 | -5.47 | -4.52 | -0.29 | -4.51 | -0.43 | -0.45 | -0.62 | -0.53 | 0.46 | -0.69 |
| EPS Growth % | 46.3% | 55.23% | -302.49% | 0.78% | -45.45% | 42.89% | 151.37% | 14.82% | -924.14% | -7.52% | -1172.09% | -904.44% | 53.23% | -751.09% | -193.48% | 34.78% | 12.68% | 31.17% | 177.97% | 93.68% |
| EPS (Basic) | -2.32 | -1.02 | -15.16 | -3.82 | -4.32 | -2.77 | 2.81 | -3.85 | -3.79 | -4.85 | -5.47 | -4.52 | -0.29 | -4.51 | -0.43 | -0.45 | -0.62 | -0.53 | 0.51 | -0.69 |
| Diluted Shares Outstanding | 28.94M | 24.71M | 18.21M | 8.67M | 8.62M | 8.47M | 8.39M | 8.33M | 10.29M | 7.7M | 7.65M | 7.63M | 114.21M | 7.57M | 89.93M | 80.21M | 79.65M | 77.57M | 86.88M | 75.46M |
| Basic Shares Outstanding | 28.94M | 22.01M | 6.74M | 8.67M | 8.62M | 8.47M | 8.39M | 8.33M | 8.07M | 7.7M | 7.65M | 7.63M | 114.21M | 7.57M | 89.93M | 80.21M | 79.65M | 77.57M | 75.67M | 75.46M |
| Dividend Payout Ratio | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |