Karyopharm Therapeutics Inc. (KPTI) Stock Price History
Historical prices from 2013 to 2026
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KPTI Historical Performance
Short-Term Returns
KPTI Stock Price Trajectory (2013–2026)
As of May 8, 2026, Karyopharm Therapeutics Inc. (KPTI) trades at $8.85, representing a +44.8% return over the past year. The stock has delivered a -93.0% total return over five years (-41.2% CAGR), reflecting challenging market conditions.
The stock reached its all-time high of $734.40 on December 8, 2014. From this peak, KPTI has corrected -98.8%, currently trading 31% above its 200-day moving average, indicating continued institutional support.
When compared to Healthcare sector peers PTCT (+58.2% 1Y), FOLD (+137.9% 1Y), and MGNX (+97.3% 1Y), KPTI has underperformed the peer group average. Compare KPTI vs PTCT →
KPTI Historical Price Data (2025–2026)
Showing 30 of 3,144 recordsLoading full history…
| Date | Open | High | Low | Close | Volume | Change % |
|---|---|---|---|---|---|---|
| 2026-05-07 | 9.15 | 9.15 | 8.68 | 8.85 | 165K | -1.88% |
| 2026-05-06 | 9.54 | 9.54 | 9.02 | 9.02 | 179K | -4.14% |
| 2026-05-05 | 9.31 | 9.53 | 9.21 | 9.41 | 190K | +1.18% |
| 2026-05-04 | 8.75 | 9.55 | 8.67 | 9.30 | 186K | +6.04% |
| 2026-05-01 | 8.35 | 8.81 | 8.25 | 8.77 | 229K | +5.54% |
| 2026-04-30 | 8.44 | 8.65 | 8.17 | 8.31 | 303K | -1.07% |
| 2026-04-29 | 8.59 | 8.59 | 8.11 | 8.40 | 265K | -2.33% |
| 2026-04-28 | 8.71 | 8.93 | 8.50 | 8.60 | 220K | -0.69% |
| 2026-04-27 | 8.99 | 9.22 | 8.60 | 8.66 | 459K | 0.00% |
| 2026-04-24 | 8.77 | 8.77 | 8.41 | 8.66 | 268K | -1.03% |
| 2026-04-23 | 9.61 | 9.61 | 8.72 | 8.75 | 514K | -8.38% |
| 2026-04-22 | 9.31 | 9.66 | 9.11 | 9.55 | 479K | +4.14% |
| 2026-04-21 | 8.87 | 9.60 | 8.73 | 9.17 | 952K | +2.57% |
| 2026-04-20 | 8.54 | 9.00 | 8.26 | 8.94 | 186K | +3.83% |
| 2026-04-17 | 8.89 | 8.89 | 8.46 | 8.61 | 165K | -0.58% |
| 2026-04-16 | 8.58 | 8.94 | 8.51 | 8.66 | 225K | +1.17% |
| 2026-04-15 | 8.60 | 8.81 | 8.40 | 8.56 | 347K | +1.30% |
| 2026-04-14 | 8.40 | 8.57 | 8.30 | 8.45 | 560K | +2.05% |
| 2026-04-13 | 8.10 | 8.87 | 8.04 | 8.28 | 1.02M | +3.50% |
| 2026-04-10 | 8.16 | 8.24 | 7.81 | 8.00 | 450K | -1.96% |
| 2026-04-09 | 7.31 | 8.25 | 7.19 | 8.16 | 1.20M | +12.55% |
| 2026-04-08 | 7.30 | 7.72 | 7.08 | 7.25 | 486K | +0.55% |
| 2026-04-07 | 6.22 | 7.25 | 5.96 | 7.21 | 1.03M | +14.08% |
| 2026-04-06 | 5.90 | 6.55 | 5.85 | 6.32 | 536K | +7.30% |
| 2026-04-02 | 5.63 | 6.10 | 5.50 | 5.89 | 182K | +1.20% |
| 2026-04-01 | 5.61 | 5.86 | 5.39 | 5.82 | 586K | +4.49% |
| 2026-03-31 | 5.31 | 5.75 | 5.31 | 5.57 | 505K | +5.09% |
| 2026-03-30 | 5.40 | 5.53 | 5.25 | 5.30 | 819K | -3.28% |
| 2026-03-27 | 5.51 | 5.77 | 5.40 | 5.48 | 840K | -1.62% |
| 2026-03-26 | 5.08 | 5.61 | 5.00 | 5.57 | 4.20M | +6.91% |
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Start ComparisonKPTI — Frequently Asked Questions
Quick answers to the most common questions about buying KPTI stock.
How has KPTI stock performed recently?
KPTI returned +44.8% over the past year, beating its 5-year annualized CAGR of -41.2%. The stock trades above its 200-day moving average, confirming the uptrend.
What is KPTI's all-time high price?
Karyopharm Therapeutics Inc. reached $734.40 on 2014-12-08. The 52-week high is $10.99. Current 1-year return of +44.8% places the stock closer to historical peaks.
Where can I download KPTI historical price data?
This page provides KPTI daily OHLCV data with 50-day MA, 200-day MA, and RSI indicators. Data spans 2013-2026, downloadable in CSV format.