Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in LIXT held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | SCOTIA CAPITAL INC. | 283K | $869K | +9.4% | 2.600% | 0.00% |
| 2 | RENAISSANCE TECHNOLOGIES LLC | 93K | $286K | -13.5% | 0.854% | 0.00% |
| 3 | Federation des caisses Desjardins du Quebec | 64K | $198K | -30.9% | 0.592% | 0.00% |
| 4 | GEODE CAPITAL MANAGEMENT, LLC | 59K | $181K | +12.8% | 0.540% | 0.00% |
| 5 | CITADEL ADVISORS LLC | 57K | $174K | +301.3% | 0.519% | 0.00% |
| 6 | VANGUARD CAPITAL MANAGEMENT LLC | 49K | $152K | — | 0.454% | 0.00% |
| 7 | VANGUARD FIDUCIARY TRUST CO | 35K | $108K | — | 0.322% | 0.00% |
| 8 | Ethos Financial Group, LLC | 25K | $76K | 0.0% | 0.228% | 0.01% |
| 9 | XTX Topco Ltd | 23K | $72K | +61.2% | 0.215% | 0.00% |
| 10 | STATE STREET CORP | 17K | $53K | 0.0% | 0.160% | 0.00% |
| 11 | Atlas Legacy Advisors, LLC | 14K | $42K | 0.0% | 0.127% | 0.01% |
| 12 | Tower Research Capital LLC (TRC) | 973 | $3K | — | 0.009% | 0.00% |
| 13 | SBI Securities Co., Ltd. | 190 | $583 | 0.0% | 0.002% | 0.00% |
| 14 | HRT FINANCIAL LP | 11K | $34 | — | 0.104% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in LIXT — a direct measure of their conviction.
Filings activity in LIXT during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 14 | 13% | 3.28% | 0.81 pp | $2M | 20% |
| Q4 2025 | 16 | +6.7% | 4.09% | +1.18 pp | $3M | +40% |
| Q3 2025 | 15 | +36% | 2.91% | +2.69 pp | $2M | +1226% |
| Q2 2025 | 11 | +10% | 0.22% | 0.16 pp | $0M | 42% |
| Q1 2025 | 10 | 9.1% | 0.38% | 0.40 pp | $0M | 51% |
| Q4 2024 | 11 | +38% | 0.78% | +0.38 pp | $1M | +94% |
| Q3 2024 | 8 | +14% | 0.40% | +0.04 pp | $0M | +10% |
| Q2 2024 | 7 | — | 0.36% | — | $0M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying LIXT stock.
Based on Q1 2026 13F filings, institutional ownership of Lixte Biotechnology Holdings, Inc. stands at 3.3%, held across 14 reporting institutions.
SCOTIA CAPITAL INC. is the largest reported institutional holder of LIXT, with approximately 283,162 shares worth $0.00B as of Q1 2026.
Yes — 2 widely-followed marquee investors appear among the top 25 institutional holders of LIXT, including RENAISSANCE TECHNOLOGIES LLC, CITADEL ADVISORS LLC.
Our composite Smart Money Score for LIXT is 43 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
4 institutions opened new positions in LIXT during Q1 2026, while 6 fully exited. 2 added to existing positions and 8 trimmed.
LIXT institutional ownership fell by 0.81 percentage points quarter-over-quarter, with a net change of -2 holders.
The top 10 institutions account for 97.9% of all reported 13F value in LIXT, and the top 25 account for 100.0%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Lixte Biotechnology Holdings, Inc. (LIXT) Institutional Ownership