Last 36 quarters of trend data · Healthcare · Biotechnology
Quarterly valuation ratios — annualised for comparability. YoY Δ shows same-quarter-prior-year change.
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P/E Ratio → | -7.60 | 1.98 | — | 10.46 | — | — | — | — | — | — | — | 5.48 | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| P/S Ratio | 12.28 | 0.99 | 600.74 | 2.14 | 406.22 | 35.59 | 69.55 | 4.97 | 6.84 | 240.27 | 139.48 | 54.72 | 14.32 | 26.27 | 18.86 | — | 19.51 | 7.86 | 27.35 | 12.46 | 20.95 |
| — | -97.2% | +763.7% | -57.0% | +5834.7% | -85.2% | -50.1% | -90.9% | -52.2% | +814.7% | +639.7% | — | -26.6% | +234.3% | -31.1% | — | -6.9% | -76.5% | -20.8% | -66.5% | -13.4% | |
| P/B Ratio | — | 5.87 | — | — | — | 177.51 | 16.19 | 6.27 | 3.12 | 3.39 | 3.19 | 3.23 | 3.18 | 3.01 | 2.79 | 2.44 | 3.06 | 2.38 | 3.82 | 5.66 | 3.10 |
| — | -96.7% | — | — | — | +5142.1% | +406.8% | +94.0% | -1.9% | +12.5% | +14.6% | +32.2% | +3.8% | +26.4% | -27.1% | -56.8% | -1.1% | -28.4% | +33.0% | +139.4% | +12.6% | |
| P/FCF | — | — | 11.14 | 4.04 | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBITDA | — | 0.96 | — | 5.63 | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| EV / EBIT | — | 0.96 | — | 9.20 | — | — | — | — | — | — | — | 4.29 | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
Quarterly margins and returns. Watch for margin compression across consecutive quarters.
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 94.0% | 97.8% | -994.2% | 99.4% | 23.7% | 27.5% | 28.5% | 44.8% | -9.9% | 100.0% | -369.9% | -91.8% | 100.0% | 8.3% | 7.3% | 100.0% | 57.9% | 80.6% | 62.4% | 90.2% | 100.0% |
| — | +255.5% | -3594.2% | +121.8% | +340.1% | -72.5% | +107.7% | +148.8% | -109.9% | +1108.2% | -5195.7% | -191.8% | +72.7% | -89.7% | -88.4% | +10.9% | -42.1% | -19.4% | -37.6% | -9.8% | 0.0% | |
| Operating Margin | -130.2% | 76.0% | -13930.7% | 35.1% | -11232.0% | -1213.6% | -2159.7% | -147.2% | -367.0% | -16279.8% | -6710.5% | -2144.8% | -642.0% | -813.1% | -952.6% | 776.4% | -473.6% | -220.8% | -510.1% | -38.6% | -324.6% |
| — | +106.3% | -545.0% | +123.9% | -2960.4% | +92.5% | +67.8% | +93.1% | +42.8% | -1902.1% | -604.4% | -376.3% | -35.6% | -268.2% | -86.7% | +2111.0% | -45.9% | +44.8% | -6.4% | +88.9% | -96.1% | |
| Net Margin | -140.3% | 50.0% | -15806.5% | 20.0% | -12320.2% | -1051.1% | -2075.9% | -184.2% | -360.5% | -17241.1% | -2932.9% | 990.9% | -868.1% | -835.6% | -910.7% | 516.5% | -774.2% | -315.8% | -551.1% | -47.1% | -373.5% |
| — | +104.8% | -661.4% | +110.9% | -3317.6% | +93.9% | +29.2% | -118.6% | +58.5% | -1963.3% | -222.0% | +91.9% | -12.1% | -164.6% | -65.3% | +1196.5% | -107.3% | +19.6% | -7.2% | +82.9% | -195.7% |
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | -368.2% | 203.9% | — | — | — | -215.2% | -79.2% | -48.2% | -44.8% | -48.2% | -15.7% | 17.6% | -41.1% | -27.7% | -29.2% | -22.7% | -28.2% | -22.4% | -17.9% | -5.3% | -13.2% |
| — | +194.8% | — | — | — | -346.5% | -403.7% | -374.1% | -8.8% | -74.1% | +46.1% | +177.3% | -46.0% | -23.5% | -63.1% | -327.8% | -113.7% | -137.9% | -74.2% | -6.0% | -260.6% | |
| ROA | -44.4% | 50.1% | -18.9% | 7.0% | -26.0% | -18.4% | -16.2% | -13.8% | -13.9% | -16.9% | -5.3% | 5.6% | -15.3% | -9.9% | -10.0% | -8.8% | -13.5% | -12.6% | -10.2% | -3.2% | -8.2% |
| — | +373.2% | -16.9% | +150.2% | -87.3% | -8.7% | -204.0% | -348.4% | +9.4% | -70.8% | +46.8% | +163.2% | -14.0% | +21.4% | +2.0% | -177.3% | -63.5% | -108.7% | -52.1% | +0.2% | -273.6% | |
| ROIC | -241.1% | 256.8% | — | 80.0% | -82.3% | -68.1% | -64.7% | -43.5% | -47.2% | -43.4% | -37.2% | -30.3% | -20.4% | -18.4% | -22.9% | -31.7% | -17.8% | -21.7% | -30.1% | -8.7% | -26.5% |
| — | +477.2% | — | +283.9% | -74.3% | -56.7% | -74.1% | -43.6% | -131.2% | -136.6% | -62.0% | +4.3% | -14.9% | +15.3% | +23.7% | -264.4% | +33.0% | +27.5% | +13.2% | +69.2% | +63.0% |
Quarterly solvency trend — watch for debt spikes or covenant pressure.
| Metric | TTM | Q2 '26 | Q1 '26 | Q4 '25 | Q3 '25 | Q2 '25 | Q1 '25 | Q4 '24 | Q3 '24 | Q2 '24 | Q1 '24 | Q4 '23 | Q3 '23 | Q2 '23 | Q1 '23 | Q4 '22 | Q3 '22 | Q2 '22 | Q1 '22 | Q4 '21 | Q3 '21 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | — | 0.52 | — | — | — | 27.19 | 2.44 | 1.25 | 0.91 | 1.09 | 0.73 | 0.65 | 0.98 | 0.74 | 1.02 | 0.78 | 0.75 | 0.16 | 0.15 | 0.13 | 0.13 |
| — | -98.1% | — | — | — | +2384.9% | +236.6% | +93.5% | -7.7% | +48.2% | -28.6% | -17.5% | +30.9% | +361.8% | +572.4% | +512.1% | +473.8% | +28.8% | +46.7% | +37.3% | +21.6% | |
| Debt / EBITDA | — | 0.35 | — | 2.99 | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — |
| — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | — | |
| Current Ratio | 0.75 | 3.76 | 0.55 | 0.75 | 0.22 | 0.88 | 1.53 | 2.03 | 2.34 | 2.36 | 3.14 | 2.38 | 1.63 | 1.99 | 1.50 | 1.88 | 2.14 | 1.55 | 2.18 | 2.69 | 2.97 |
| — | +326.5% | -64.2% | -63.2% | -90.5% | -62.6% | -51.4% | -14.6% | +43.6% | +18.2% | +109.7% | +26.5% | -23.9% | +28.9% | -31.4% | -30.1% | -27.8% | -57.2% | -49.3% | -46.6% | -36.5% | |
| Quick Ratio | 0.75 | 3.76 | 0.55 | 0.75 | 0.22 | 0.88 | 1.51 | 2.03 | 2.34 | 2.36 | 3.14 | 2.38 | 1.52 | 1.99 | 1.50 | 1.78 | 2.14 | 1.55 | 2.18 | 2.69 | 2.97 |
| — | +329.4% | -63.9% | -63.0% | -90.5% | -62.9% | -51.8% | -14.9% | +54.0% | +18.2% | +109.7% | +33.6% | -29.1% | +28.9% | -31.4% | -33.8% | -27.8% | -57.2% | -49.3% | -46.6% | -36.5% | |
| Interest Coverage | -8.36 | 92.05 | -15.26 | 5.94 | -15.48 | -11.79 | -12.14 | -10.55 | -10.72 | -13.94 | -5.29 | 6.86 | -12.10 | -7.82 | -8.92 | -14.18 | -18.71 | -413.30 | -402.18 | -82.29 | -438.75 |
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Includes 30+ ratios · 36 years · Updated daily
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Quick answers to the most common questions about buying MGTX stock.
MeiraGTx Holdings plc's current P/E is -7.6x. The average P/E over the last 2 quarters is 6.2x. Quarterly P/E ratios can vary due to seasonal revenue patterns and one-time charges.
MeiraGTx Holdings plc's current operating margin is -130.2%. Margins have been expanding over recent quarters. Quarterly margins are particularly useful for identifying trend inflections that annual data smooths over.
Quarterly financial ratios reveal short-term trend shifts — margin compression, debt spikes, or valuation re-ratings — that annual figures smooth over. They're essential for active investors tracking MeiraGTx Holdings plc's business trajectory between earnings reports.