Ranked by reported Q3 2025 13F market value
Share of total reported institutional value in MURA held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | ORBIMED ADVISORS LLC | 589K | $1.2M | 0.0% | 3.399% | 0.03% |
| 2 | Newtyn Management, LLC | 523K | $1.1M | -8.3% | 3.018% | 0.13% |
| 3 | OMERS ADMINISTRATION Corp | 511K | $1.1M | β | 2.950% | 0.01% |
| 4 | VANGUARD GROUP INC | 455K | $941K | -41.2% | 2.625% | 0.00% |
| 5 | Rangeley Capital, LLC | 305K | $631K | +555.7% | 1.760% | 0.59% |
| 6 | BlackRock, Inc. | 288K | $595K | +0.4% | 1.660% | 0.00% |
| 7 | RBF Capital, LLC | 284K | $588K | 0.0% | 1.639% | 0.03% |
| 8 | MILLENNIUM MANAGEMENT LLC | 258K | $535K | -18.2% | 1.492% | 0.00% |
| 9 | DELTEC ASSET MANAGEMENT LLC | 179K | $371K | β | 1.034% | 0.06% |
| 10 | GEODE CAPITAL MANAGEMENT, LLC | 175K | $363K | +0.2% | 1.011% | 0.00% |
| 11 | TORNO CAPITAL, LLC | 170K | $352K | β | 0.981% | 9.96% |
| 12 | Yakira Capital Management, Inc. | 164K | $339K | β | 0.946% | 0.13% |
| 13 | RENAISSANCE TECHNOLOGIES LLC | 146K | $302K | +1137.3% | 0.843% | 0.00% |
| 14 | MORGAN STANLEY | 102K | $211K | +395.5% | 0.590% | 0.00% |
| 15 | PRIMECAP MANAGEMENT CO/CA/ | 93K | $192K | 0.0% | 0.536% | 0.00% |
| 16 | STATE STREET CORP | 85K | $176K | 0.0% | 0.490% | 0.00% |
| 17 | PenderFund Capital Management Ltd. | 83K | $171K | β | 0.478% | 0.03% |
| 18 | BML Capital Management, LLC | 58K | $119K | β | 0.332% | 0.11% |
| 19 | Shay Capital LLC | 45K | $93K | β | 0.260% | 0.01% |
| 20 | JANE STREET GROUP, LLC | 41K | $84K | β | 0.234% | 0.00% |
| 21 | DIMENSIONAL FUND ADVISORS LP | 40K | $82K | -12.7% | 0.230% | 0.00% |
| 22 | GOLDMAN SACHS GROUP INC | 38K | $78K | +67.1% | 0.218% | 0.00% |
| 23 | NORTHERN TRUST CORP | 33K | $69K | -9.4% | 0.192% | 0.00% |
| 24 | RAYMOND JAMES FINANCIAL INC | 18K | $38K | -15.4% | 0.105% | 0.00% |
| 25 | LMR Partners LLP | 16K | $34K | -96.8% | 0.095% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). β% of Fundβ shows how much of that investorβs total 13F portfolio is invested in MURA β a direct measure of their conviction.
Filings activity in MURA during Q3 2025, grouped by how each filer changed its position.
Institutions that opened a new MURA position in Q3 2025
Institutions that fully closed their MURA position in Q3 2025
7 quarters of 13F filings Β· Ξ columns show change vs prior quarter
| Quarter | Inst. Holders | Ξ Holders | Ownership % | Ξ Ownership | Total 13F Value | Ξ Value |
|---|---|---|---|---|---|---|
| Q3 2025 | 57 | 11% | 27.94% | 32.91 pp | $10M | 54% |
| Q2 2025 | 64 | 3.0% | 60.85% | +31.30 pp | $22M | +106% |
| Q1 2025 | 66 | 14% | 29.55% | 52.18 pp | $10M | 64% |
| Q4 2024 | 77 | +6.9% | 81.73% | +2.93 pp | $29M | +3.7% |
| Q3 2024 | 72 | 13% | 78.80% | 12.51 pp | $28M | 14% |
| Q2 2024 | 83 | 14% | 91.31% | 67.27 pp | $32M | 42% |
| Q1 2024 | 97 | β | 158.58% | β | $56M | β |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Ξ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying MURA stock.
Based on Q3 2025 13F filings, institutional ownership of Mural Oncology plc stands at 27.9%, held across 57 reporting institutions.
ORBIMED ADVISORS LLC is the largest reported institutional holder of MURA, with approximately 588,800 shares worth $0.00B as of Q3 2025.
Yes β 3 widely-followed marquee investors appear among the top 25 institutional holders of MURA, including MILLENNIUM MANAGEMENT LLC, RENAISSANCE TECHNOLOGIES LLC, JANE STREET GROUP, LLC.
Our composite Smart Money Score for MURA is 44 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
14 institutions opened new positions in MURA during Q3 2025, while 21 fully exited. 6 added to existing positions and 31 trimmed.
MURA institutional ownership fell by 32.91 percentage points quarter-over-quarter, with a net change of -7 holders.
The top 10 institutions account for 74.8% of all reported 13F value in MURA, and the top 25 account for 98.5%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.