Ranked by reported Q1 2026 13F market value
Share of total reported institutional value in NAUT held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | a16z Capital Management, L.L.C. | 17.7M | $68.5M | 0.0% | 13.892% | 5.31% |
| 2 | PERCEPTIVE ADVISORS LLC | 12.6M | $48.9M | 0.0% | 9.910% | 0.97% |
| 3 | Cercano Management LLC | 7.2M | $27.8M | 0.0% | 5.644% | 1.20% |
| 4 | VANGUARD CAPITAL MANAGEMENT LLC | 2.5M | $9.9M | — | 2.003% | 0.00% |
| 5 | Clearstead Advisors, LLC | 2.3M | $9.0M | — | 1.833% | 0.08% |
| 6 | Comprehensive Financial Management LLC | 2.2M | $8.6M | 0.0% | 1.737% | 0.28% |
| 7 | AMAZON COM INC | 1.5M | $5.7M | 0.0% | 1.147% | 0.21% |
| 8 | MILLENNIUM MANAGEMENT LLC | 1.3M | $4.9M | +24.8% | 1.002% | 0.00% |
| 9 | Tikvah Management LLC | 727K | $2.8M | 0.0% | 0.572% | 0.87% |
| 10 | GEODE CAPITAL MANAGEMENT, LLC | 604K | $2.3M | +7.6% | 0.475% | 0.00% |
| 11 | GOLDMAN SACHS GROUP INC | 391K | $1.5M | +31.4% | 0.307% | 0.00% |
| 12 | DIMENSIONAL FUND ADVISORS LP | 329K | $1.3M | +15.3% | 0.259% | 0.00% |
| 13 | MARSHALL WACE, LLP | 320K | $1.2M | +173.3% | 0.252% | 0.00% |
| 14 | VANGUARD FIDUCIARY TRUST CO | 306K | $1.2M | — | 0.240% | 0.00% |
| 15 | RENAISSANCE TECHNOLOGIES LLC | 266K | $1.0M | +2.2% | 0.209% | 0.00% |
| 16 | STATE STREET CORP | 216K | $839K | +7.5% | 0.170% | 0.00% |
| 17 | HILLMAN CO | 200K | $776K | 0.0% | 0.157% | 0.30% |
| 18 | BlackRock, Inc. | 188K | $728K | -0.9% | 0.148% | 0.00% |
| 19 | Crewe Advisors LLC | 136K | $528K | 0.0% | 0.107% | 0.05% |
| 20 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 130K | $504K | 0.0% | 0.102% | 0.01% |
| 21 | Corient Private Wealth LLC | 115K | $445K | 0.0% | 0.090% | 0.00% |
| 22 | NORTHERN TRUST CORP | 107K | $415K | 0.0% | 0.084% | 0.00% |
| 23 | Point72 Asset Management, L.P. | 83K | $322K | +36.5% | 0.065% | 0.00% |
| 24 | Qube Research & Technologies Ltd | 80K | $309K | -35.3% | 0.063% | 0.00% |
| 25 | BARCLAYS PLC | 73K | $285K | +52.0% | 0.058% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in NAUT — a direct measure of their conviction.
Filings activity in NAUT during Q1 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q1 2026 | 80 | +18% | 71.71% | +36.97 pp | $204M | +106% |
| Q4 2025 | 68 | +3.0% | 34.74% | +19.50 pp | $99M | +128% |
| Q3 2025 | 66 | 2.9% | 15.24% | +1.94 pp | $43M | +15% |
| Q2 2025 | 68 | 21% | 13.30% | 3.68 pp | $38M | 22% |
| Q1 2025 | 86 | 2.3% | 16.98% | 16.88 pp | $48M | 50% |
| Q4 2024 | 88 | +6.0% | 33.86% | 23.84 pp | $96M | 41% |
| Q3 2024 | 83 | +6.4% | 57.70% | +10.41 pp | $164M | +22% |
| Q2 2024 | 78 | — | 47.29% | — | $135M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying NAUT stock.
Based on Q1 2026 13F filings, institutional ownership of Nautilus Biotechnology, Inc. stands at 71.7%, held across 80 reporting institutions.
a16z Capital Management, L.L.C. is the largest reported institutional holder of NAUT, with approximately 17,653,917 shares worth $0.07B as of Q1 2026.
Yes — 3 widely-followed marquee investors appear among the top 25 institutional holders of NAUT, including MILLENNIUM MANAGEMENT LLC, RENAISSANCE TECHNOLOGIES LLC, Point72 Asset Management, L.P..
Our composite Smart Money Score for NAUT is 76 out of 100 (Bullish). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
25 institutions opened new positions in NAUT during Q1 2026, while 13 fully exited. 45 added to existing positions and 7 trimmed.
NAUT institutional ownership rose by 36.97 percentage points quarter-over-quarter, with a net change of +12 holders.
The top 10 institutions account for 92.3% of all reported 13F value in NAUT, and the top 25 account for 97.9%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Nautilus Biotechnology, Inc. (NAUT) Institutional Ownership