Ranked by reported Q2 2026 13F market value
Share of total reported institutional value in NAUT held by the largest 10 / 25 filers.
| # | Institution | Shares Held | Market Value | QoQ Change | Ownership % | % of Fund |
|---|---|---|---|---|---|---|
| 1 | PERCEPTIVE ADVISORS LLC | 11.6M | $21.8M | -7.6% | 9.142% | 0.33% |
| 2 | a16z Capital Management, L.L.C. | 9.1M | $16.9M | -48.7% | 7.122% | 0.12% |
| 3 | Cercano Management LLC | 7.2M | $13.4M | 0.0% | 5.637% | 0.75% |
| 4 | BlackRock, Inc. | 2.7M | $5.0M | +1331.9% | 2.112% | 0.00% |
| 5 | VANGUARD CAPITAL MANAGEMENT LLC | 2.5M | $4.8M | +0.2% | 2.004% | 0.00% |
| 6 | Comprehensive Financial Management LLC | 2.2M | $4.1M | 0.0% | 1.735% | 0.14% |
| 7 | CITADEL ADVISORS LLC | 1.9M | $3.6M | — | 1.520% | 0.00% |
| 8 | GEODE CAPITAL MANAGEMENT, LLC | 1.3M | $2.4M | +109.7% | 0.995% | 0.00% |
| 9 | Clearstead Advisors, LLC | 893K | $1.7M | -61.7% | 0.702% | 0.02% |
| 10 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 891K | $1.7M | +1710.9% | 0.700% | 0.00% |
| 11 | BARCLAYS PLC | 725K | $1.4M | +889.2% | 0.570% | 0.00% |
| 12 | RENAISSANCE TECHNOLOGIES LLC | 691K | $1.3M | +159.9% | 0.543% | 0.00% |
| 13 | JPMORGAN CHASE & CO | 614K | $1.1M | — | 0.483% | 0.00% |
| 14 | STATE STREET CORP | 560K | $1.0M | +158.7% | 0.440% | 0.00% |
| 15 | DIMENSIONAL FUND ADVISORS LP | 476K | $889K | +44.6% | 0.374% | 0.00% |
| 16 | NORTHERN TRUST CORP | 381K | $713K | +256.3% | 0.300% | 0.00% |
| 17 | VANGUARD FIDUCIARY TRUST CO | 353K | $660K | +15.6% | 0.278% | 0.00% |
| 18 | VANGUARD PORTFOLIO MANAGEMENT LLC | 338K | $632K | — | 0.265% | 0.00% |
| 19 | MARSHALL WACE, LLP | 266K | $497K | -17.0% | 0.209% | 0.00% |
| 20 | Qube Research & Technologies Ltd | 257K | $481K | +223.2% | 0.202% | 0.00% |
| 21 | GOLDMAN SACHS GROUP INC | 253K | $473K | -35.3% | 0.199% | 0.00% |
| 22 | HILLMAN CO | 200K | $374K | 0.0% | 0.157% | 0.13% |
| 23 | MILLENNIUM MANAGEMENT LLC | 189K | $353K | -85.2% | 0.148% | 0.00% |
| 24 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 180K | $337K | +38.5% | 0.141% | 0.01% |
| 25 | Corient Private Wealth LP | 165K | $308K | +43.6% | 0.130% | 0.00% |
denotes a marquee investor (Buffett, Burry, ARK, Tiger Global, Pershing Square, Baupost and other widely-followed managers). “% of Fund” shows how much of that investor’s total 13F portfolio is invested in NAUT — a direct measure of their conviction.
Filings activity in NAUT during Q2 2026, grouped by how each filer changed its position.
8 quarters of 13F filings · Δ columns show change vs prior quarter
| Quarter | Inst. Holders | Δ Holders | Ownership % | Δ Ownership | Total 13F Value | Δ Value |
|---|---|---|---|---|---|---|
| Q2 2026 | 93 | +12% | 39.44% | 3.36 pp | $89M | 56% |
| Q1 2026 | 83 | +22% | 42.80% | 3.25 pp | $204M | +107% |
| Q4 2025 | 68 | +3.0% | 46.05% | +0.23 pp | $99M | +128% |
| Q3 2025 | 66 | 2.9% | 45.82% | 0.76 pp | $43M | +15% |
| Q2 2025 | 68 | 21% | 46.58% | 3.09 pp | $38M | 22% |
| Q1 2025 | 86 | 2.3% | 49.67% | 0.96 pp | $48M | 50% |
| Q4 2024 | 88 | +6.0% | 50.63% | 0.42 pp | $96M | 41% |
| Q3 2024 | 83 | — | 51.05% | — | $164M | — |
Source: SEC 13F institutional filings. Ownership % requires market cap data and will show once linked. Δ columns compare to the immediately prior filed quarter.
Quick answers to the most common questions about buying NAUT stock.
Based on Q2 2026 13F filings, institutional ownership of Nautilus Biotechnolgy, Inc. stands at 39.4%, held across 93 reporting institutions.
PERCEPTIVE ADVISORS LLC is the largest reported institutional holder of NAUT, with approximately 11,634,211 shares worth $0.02B as of Q2 2026.
Yes — 4 widely-followed marquee investors appear among the top 25 institutional holders of NAUT, including CITADEL ADVISORS LLC, SUSQUEHANNA INTERNATIONAL GROUP, LLP, RENAISSANCE TECHNOLOGIES LLC, MILLENNIUM MANAGEMENT LLC.
Our composite Smart Money Score for NAUT is 55 out of 100 (Neutral). It combines net institutional buying activity, ownership shift, marquee investor presence, and holder-count growth.
29 institutions opened new positions in NAUT during Q2 2026, while 18 fully exited. 13 added to existing positions and 48 trimmed.
NAUT institutional ownership fell by 3.36 percentage points quarter-over-quarter, with a net change of +10 holders.
The top 10 institutions account for 84.3% of all reported 13F value in NAUT, and the top 25 account for 96.1%.
All data is sourced from SEC Form 13F filings, which institutional investment managers with at least $100M in assets are required to file each quarter. We process every 13F filing from EDGAR and recompute the aggregates after each cycle. Insider transactions are sourced from Form 4 filings.
Nautilus Biotechnolgy, Inc. (NAUT) Institutional Ownership